<?xml version="1.0" encoding="utf-8"?>
<!--Created on: 27/08/2010 12:31:59-->
<sbml xmlns="http://www.sbml.org/sbml/level2" xmlns:html="http://www.w3.org/1999/xhtml" level="2" version="1">
    <model id="MODELID_1461534" name="E. coli iJR904">
        <annotation xmlns="">
            <fba:fluxBalance xmlns:fba="http://www.sbml.org/sbml/level3/version1/fba/version1">
                <fba:listOfConstraints>
                    <fba:constraint fba:reaction="R_12PPDt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_12PPDt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_2DGLCNRx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_2DGLCNRx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_2DGLCNRy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_2DGLCNRy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_2DGULRx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_2DGULRx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_2DGULRy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_2DGULRy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_3HCINNMH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_3HCINNMH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_3HPPPNH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_3HPPPNH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_4HTHRS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_4HTHRS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_5DGLCNR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_5DGLCNR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_A5PISO" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_A5PISO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AACPS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AACPS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AACPS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AACPS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AACPS3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AACPS3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AACPS4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AACPS4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AACPS5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AACPS5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AADDGT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AADDGT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AB6PGH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AB6PGH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ABTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ABTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ABUTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ABUTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ABUTt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ABUTt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACACCT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACACCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACACT1r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACACT1r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACACt2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACACt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACALDi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACALDi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACALDt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACALDt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACBIPGT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACBIPGT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACCOACr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACCOACr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACCOAL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACCOAL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACGAMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACGAMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACGApts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACGApts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACGK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACGK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACGS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACGS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACHBS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACHBS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACKr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACKr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACLS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACLS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACMAMUT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACMAMUT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACMANApts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACMANApts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACNAMt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACNAMt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACNML" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACNML" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACOATA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACOATA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACODA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACODA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACONMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACONMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACONT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACONT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACOTA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACOTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACPS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACPS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ACS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ACt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ACt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADCL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADCL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADCS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADCS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADEt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADEt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADHEr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADHEr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADK1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADK3" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADK3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADK4" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADK4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADMDCr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADMDCr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADNCYC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADNCYC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADNK1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADNK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADOCBIK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADOCBIK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADOCBLS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADOCBLS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADSK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADSK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADSL1r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADSL1r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADSL2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ADSL2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ADSS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ADSS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AGDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AGDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AGMHE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AGMHE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AGMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AGMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AGPR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AGPR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AHC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AHC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AHCYSNS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AHCYSNS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AICART" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AICART" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AIRC2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AIRC2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AIRC3" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AIRC3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AKGDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AKGDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AKGt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AKGt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALAALAr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALAALAr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALAR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALAR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALATA_D2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALATA_D2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALATA_L" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALATA_L" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALATA_L2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALATA_L2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALAabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALAabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALAt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALAt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALCD19" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALCD19" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALDD19x" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALDD19x" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALDD2x" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALDD2x" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALLTAH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALLTAH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALLTN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALLTN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALLTNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ALLTNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ALTRH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ALTRH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMALT1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMALT1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMALT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMALT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMALT3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMALT3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMALT4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMALT4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMANAPE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMANAPE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMANK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMANK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMAOTr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AMAOTr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMMQT8_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMMQT8_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMPMS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMPMS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AMPN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AMPN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ANPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ANPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ANS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ANS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AOXSr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_AOXSr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AP4AH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AP4AH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AP5AH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AP5AH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_APRAUR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_APRAUR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARAI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ARAI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARBabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ARBabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARBt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ARBt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARGDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ARGDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARGORNt7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ARGORNt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARGSL" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ARGSL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARGSS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ARGSS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ARGabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ARGabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASAD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ASAD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASNN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASNN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASNS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASNS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASNS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASNS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASNabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASNabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ASNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASP1DC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASP1DC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPCT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPK" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ASPK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPO3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPO3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPO4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPO4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPO5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPO5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPO6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPO6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPTA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ASPTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPt2_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPt2_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ASPt2_3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ASPt2_3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_AST" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_AST" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ATPM" fba:operation="greater" fba:value="7.6" />
                    <fba:constraint fba:reaction="R_ATPM" fba:operation="less" fba:value="7.6" />
                    <fba:constraint fba:reaction="R_ATPPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ATPPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ATPS4r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ATPS4r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BETALDHx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BETALDHx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BETALDHy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BETALDHy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BPNT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BPNT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BSORx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BSORx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BSORy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BSORy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BTS2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_BTS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BUTCT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_BUTCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_BUTt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_BUTt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C120SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C120SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C140SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C140SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C141SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C141SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C160SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C160SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C161SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C161SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_C181SN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_C181SN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CADVt" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CADVt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CBIAT_DELETE" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CBIAT_DELETE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CBL1abc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CBL1abc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CBLAT_DELETE" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CBLAT_DELETE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CBMK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CBMK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CBPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CBPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CDAPPA_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CDAPPA_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CDPMEK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CDPMEK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CHLabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CHLabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CHLt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CHLt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CHORM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CHORM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CHORS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CHORS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CHRPL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CHRPL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CINNDO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CINNDO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CITL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CITL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CITt7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CITt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CLPNS_EC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CLPNS_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CMPN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CMPN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CO2t" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CO2t" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CPPPGO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CPPPGO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CRNBTCT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CRNBTCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CRNCBCT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CRNCBCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CRNCDH" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CRNCDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CRNt7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CRNt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CSND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CSND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CSNt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CSNt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CTPS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CTPS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYANST" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYANST" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYNTAH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYNTAH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYNTt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYNTt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYSDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYSDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYSS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYSS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYSTL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYSTL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYSabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYSabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTBD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYTBD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTBO3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYTBO3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTDK2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_CYTDK2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTDt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CYTDt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTK1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CYTK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_CYTK2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_CYTK2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DAAD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DAAD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DADA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DADA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DADK" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DADK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DADNt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DADNt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DAGK_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DAGK_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DALAt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DALAt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DAPDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DAPDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DAPE" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DAPE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DAPabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DAPabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DASYN_EC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DASYN_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DB4PS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DB4PS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DBTSr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DBTSr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DCTPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DCTPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DCYTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DCYTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DCYTt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DCYTt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DDGALK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DDGALK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DDGLCNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DDGLCNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DDGLK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DDGLK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DDPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DDPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DDPGALA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DDPGALA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DGK1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DGK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DGSNt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DGSNt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHAD1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHAD1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHAD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHAD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHAPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHAPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHAt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHAt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHBD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHBD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHBSr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHBSr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHCIND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHCIND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHCINDO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHCINDO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHDPRy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHDPRy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHFR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHFR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHFS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHFS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHNAOT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHNAOT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHNPA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHNPA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHORD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHORD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHORD5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHORD5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHORTS" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHORTS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHPPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHPPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHPPDA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHPPDA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHPS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHPS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHPTDCs" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHPTDCs" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHQD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DHQD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DHQS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DHQS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DINSt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DINSt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DKGLCNR1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DKGLCNR1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DKGLCNR2x" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DKGLCNR2x" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DKGLCNR2y" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DKGLCNR2y" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DKMPPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DKMPPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DKMPPD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DKMPPD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMATT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMATT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMPPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMPPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMQMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMQMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMSOR1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMSOR1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMSOR1e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMSOR1e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMSOR2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMSOR2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DMSOR2e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DMSOR2e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DNMPPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DNMPPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DNTPPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DNTPPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DOGULNR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DOGULNR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DPCOAK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DPCOAK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DPR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DPR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DRPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DRPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DSERt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DSERt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DTMPK" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DTMPK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DURIK1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DURIK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DURIPP" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_DURIPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DURIt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DURIt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DUTPDP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DUTPDP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DXPRIi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DXPRIi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DXPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DXPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_DXYLK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_DXYLK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_D_LACt2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_D_LACt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_E4PD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_E4PD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ECAP_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ECAP_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDTXS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDTXS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDTXS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDTXS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDTXS3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDTXS3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EDTXS4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EDTXS4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ENO" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ENO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ENTCS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ENTCS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ETHAAL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ETHAAL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ETOHt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ETOHt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_12ppd_S_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_12ppd_S_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_15dap_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_15dap_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_26dap_M_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_26dap_M_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_2ddglcn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_2ddglcn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_3hcinnm_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_3hcinnm_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_3hpppn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_3hpppn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_4abut_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_4abut_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ac_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ac_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_acac_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_acac_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_acald_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_acald_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_acgam_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_acgam_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_acmana_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_acmana_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_acnam_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_acnam_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ade_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ade_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_adn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_adn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_akg_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_akg_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ala_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ala_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ala_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ala_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_alltn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_alltn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_amp_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_amp_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_arab_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_arab_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_arg_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_arg_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_asn_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_asn_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_asp_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_asp_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_but_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_but_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_cbl1_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_cbl1_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_chol_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_chol_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_cit_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_cit_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_co2_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_co2_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_crn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_crn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_csn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_csn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_cynt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_cynt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_cys_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_cys_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_cytd_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_cytd_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dad_2_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dad_2_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dcyt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dcyt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dgsn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dgsn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dha_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dha_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_din_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_din_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dms_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dms_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_dmso_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_dmso_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_duri_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_duri_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_etoh_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_etoh_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_fe2_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_fe2_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_for_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_for_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_fru_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_fru_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_fuc1p_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_fuc1p_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_fuc_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_fuc_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_fum_e" fba:operation="greater" fba:value="-39.3295283958333360" />
                    <fba:constraint fba:reaction="R_EX_fum_e" fba:operation="less" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_g6p_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_g6p_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gal_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gal_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_galct_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_galct_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_galctn_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_galctn_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_galt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_galt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_galur_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_galur_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gam_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gam_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gbbtn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gbbtn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glc_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glc_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glcn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glcn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glcr_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glcr_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glcur_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glcur_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gln_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gln_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glu_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glu_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gly_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gly_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glyald_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glyald_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glyb_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glyb_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glyc3p_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glyc3p_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glyc_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glyc_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_glyclt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_glyclt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gsn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gsn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_gua_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_gua_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_h2o_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_h2o_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_h_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_h_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_hdca_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_hdca_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_his_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_his_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_hxan_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_hxan_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_idon_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_idon_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ile_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ile_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_indole_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_indole_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ins_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ins_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_k_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_k_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_lac_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_lac_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_lac_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_lac_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_lcts_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_lcts_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_leu_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_leu_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_lys_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_lys_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_mal_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_mal_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_malt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_malt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_malthx_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_malthx_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_maltpt_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_maltpt_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_malttr_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_malttr_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_maltttr_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_maltttr_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_man6p_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_man6p_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_man_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_man_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_melib_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_melib_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_met_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_met_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_met_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_met_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_mnl_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_mnl_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_na1_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_na1_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_nac_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_nac_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_nad_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_nad_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_nh4_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_nh4_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_nmn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_nmn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_no2_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_no2_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_no3_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_no3_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_o2_e" fba:operation="greater" fba:value="-20" />
                    <fba:constraint fba:reaction="R_EX_o2_e" fba:operation="less" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ocdca_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ocdca_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_orn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_orn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_phe_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_phe_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_pi_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_pi_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_pnto_R_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_pnto_R_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_pppn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_pppn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_pro_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_pro_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ptrc_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ptrc_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_pyr_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_pyr_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_rib_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_rib_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_rmn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_rmn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_sbt_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_sbt_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ser_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ser_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ser_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ser_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_so4_e" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_EX_so4_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_spmd_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_spmd_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_succ_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_succ_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_sucr_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_sucr_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tartr_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tartr_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_taur_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_taur_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_thm_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_thm_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_thr_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_thr_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_thymd_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_thymd_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tma_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tma_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tmao_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tmao_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tre_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tre_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_trp_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_trp_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tsul_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tsul_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ttdca_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ttdca_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_tyr_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_tyr_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_ura_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_ura_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_urea_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_urea_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_uri_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_uri_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_val_L_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_val_L_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_xan_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_xan_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_xtsn_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_xtsn_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_EX_xyl_D_e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_EX_xyl_D_e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_F6PA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_F6PA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FAO1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FAO1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FAO2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FAO2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FAO3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FAO3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FAO4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FAO4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FBA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FBA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FBP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FBP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FCI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FCI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FCLK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FCLK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FCLPA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FCLPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FCLT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FCLT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FDH2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FDH2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FDH3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FDH3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FE2abc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FE2abc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FFSD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FFSD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FHL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FHL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FMNAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FMNAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FORt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FORt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FRD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FRD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FRD3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FRD3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FRUK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FRUK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FRUpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FRUpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FRUpts2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FRUpts2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FTHFD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FTHFD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FUCPt6_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FUCPt6_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FUCt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FUCt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FUM" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_FUM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FUMt2_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FUMt2_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_FUMt2_3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_FUMt2_3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G1PACT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G1PACT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G1PP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G1PP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G1PTT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G1PTT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G1SATi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G1SATi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G3PD2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_G3PD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G3PD5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G3PD5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G3PD6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G3PD6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G3PD7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G3PD7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G5SADs" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G5SADs" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G5SD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G5SD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G6PDA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G6PDA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G6PDH2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_G6PDH2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_G6Pt6_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_G6Pt6_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALCTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALCTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALCTND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALCTND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALCTNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GALCTNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALCTt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GALCTt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALKr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GALKr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALS3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALS3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALTpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALTpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALU" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GALU" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALURt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GALURt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GALt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GALt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GAMpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GAMpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GAPD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GAPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GARFT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GARFT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GART" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GART" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GCALDD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GCALDD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GDMANE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GDMANE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GF6PTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GF6PTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GHMT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GHMT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GK1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCDe" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCDe" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLCNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCRAL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCRAL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCRD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCRD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCRt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLCRt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCURt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLCURt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLCt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLCt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLGC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLGC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLNS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLNS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLNabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLNabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLTPD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLTPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLU5K" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLU5K" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUABUTt7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLUABUTt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUCYS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUCYS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUDy" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLUDy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLUR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUSy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUSy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUTRR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUTRR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUTRS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUTRS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLUt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLUt4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLUt4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLXCL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLXCL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYALDt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLYALDt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYATi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYATi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYBabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYBabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYBt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLYBt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYC3Pabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYC3Pabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYC3Pt6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYC3Pt6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCDx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCDx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCLTDx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCLTDx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCLTDy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCLTDy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCLTt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLYCLTt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCTO2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCTO2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCTO3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCTO3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCTO4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYCTO4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYCt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLYCt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYOX" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GLYOX" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GLYt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GLYt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMAND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMAND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMHEPAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMHEPAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMHEPK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMHEPK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMHEPPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMHEPPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMPR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMPR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GMPS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GMPS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GNK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GNK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GOFUCR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GOFUCR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GP4GH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GP4GH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GPDDA1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GPDDA1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GPDDA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GPDDA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GPDDA3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GPDDA3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GPDDA4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GPDDA4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GPDDA5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GPDDA5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GRTT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GRTT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GSNK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GSNK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GSNt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GSNt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GSPMDA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GSPMDA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GSPMDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GSPMDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GTHOr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GTHOr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GTHS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GTHS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GTPCI" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GTPCI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GTPCII2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GTPCII2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUAD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GUAD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUAPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GUAPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUAt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GUAt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUAt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_GUAt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUI1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GUI1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_GUI2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_GUI2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_H2Ot" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_H2Ot" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HBZOPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HBZOPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HCINNMt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HCINNMt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HCO3E" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HCO3E" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HDCAt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HDCAt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HEMEOS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HEMEOS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HETZK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HETZK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HEX1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HEX1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HISTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HISTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HISTP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HISTP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HISabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HISabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HISt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HISt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HKNDDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HKNDDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HKNTDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HKNTDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HMBS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HMBS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HMPK1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HMPK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HOPNTAL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HOPNTAL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPPK2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HPPK2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPPPNDO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HPPPNDO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPPPNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HPPPNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPYRI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HPYRI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPYRRx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HPYRRx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HPYRRy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HPYRRy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HSDy" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HSDy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HSK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HSK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HSST" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HSST" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HSTPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HSTPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HXPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HXPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HYD1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HYD1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HYD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HYD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HYD3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HYD3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HYPOE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_HYPOE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_HYXNt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_HYXNt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ICDHyr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ICDHyr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ICHORSi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ICHORSi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ICHORT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ICHORT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ICL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ICL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IDOND" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_IDOND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IDOND2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IDOND2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IDONt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_IDONt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IG3PS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IG3PS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IGPDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IGPDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IGPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IGPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ILETA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ILETA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ILEabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ILEabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ILEt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ILEt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IMPC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_IMPC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IMPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IMPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_INDOLEt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_INDOLEt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_INSK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_INSK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_INSt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_INSt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPDDIi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IPDDIi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IPDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPMD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IPMD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPPMIa" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_IPPMIa" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPPMIb" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_IPPMIb" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_IPPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_IPPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KARA1i" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KARA1i" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KARA2i" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KARA2i" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KAS14" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KAS14" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KAS15" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KAS15" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KAS16" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KAS16" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KDOCT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KDOCT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KDOPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KDOPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KDOPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KDOPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_KG6PDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_KG6PDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_Kabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_Kabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_Kt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_Kt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LACZ" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LACZ" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LCAD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LCAD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LCARS" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LCARS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LCTSt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LCTSt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LDH_D" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LDH_D" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LDH_D2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LDH_D2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LEUTAi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LEUTAi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LEUabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LEUabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LEUt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LEUt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LGTHL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LGTHL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPADSS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPADSS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPLIPA6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPLIPA6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LPSSYN_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LPSSYN_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LYSDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LYSDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LYSabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_LYSabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_LYSt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_LYSt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_L_LACD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_L_LACD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_L_LACD3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_L_LACD3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_L_LACt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_L_LACt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_M1PD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_M1PD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MACPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MACPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTHXabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTHXabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTPTabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTPTabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTTRabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTTRabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTTTRabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTTTRabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALTpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALTpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALt2_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALt2_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MALt2_3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MALt2_3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MAN1PT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MAN1PT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MAN6PI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MAN6PI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MAN6Pt6_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MAN6Pt6_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MANAO" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MANAO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MANpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MANpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MCITD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MCITD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MCITL2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MCITL2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MCITS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MCITS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MCOATA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MCOATA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MDH" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MDH2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MDH2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MDH3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MDH3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MDRPD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MDRPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ME1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ME1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ME2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ME2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MECDPDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MECDPDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MECDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MECDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MELIBt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MELIBt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MEPCT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MEPCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_METAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_METAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_METDabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_METDabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_METS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_METS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_METabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_METabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MGSA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MGSA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MI1PP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MI1PP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MICITD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MICITD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTG1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MLTG1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTG2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MLTG2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTG3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MLTG3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTG4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MLTG4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTG5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MLTG5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTP1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MLTP1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTP2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MLTP2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MLTP3" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MLTP3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MMCD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MMCD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MME" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MME" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MMM2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MMM2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MNLpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MNLpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MNNH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MNNH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MOAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MOAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MOAT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MOAT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MOHMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MOHMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTAN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MTAN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTHFC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MTHFC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTHFD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MTHFD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTHFR2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MTHFR2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTRI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_MTRI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_MTRK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_MTRK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NACODA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NACODA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NACUP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NACUP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADDP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADDP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADDPe" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADDPe" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH10" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH10" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH8" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH8" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADH9" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADH9" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADPPPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADPPPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NADTRHD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NADTRHD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NAMNPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NAMNPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NAt3_1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NAt3_1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NAt3_15" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NAt3_15" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NAt3_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NAt3_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK3" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK4" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK5" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK6" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NDPK8" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NDPK8" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NH4t" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NH4t" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NMNAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NMNAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NMNDA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NMNDA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NMNN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NMNN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NMNP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NMNP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NMNt7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NMNt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NNAM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NNAM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NNAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NNAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NNDMBRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NNDMBRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NNDPR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NNDPR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NO2t2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_NO2t2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NO3R1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NO3R1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NO3R2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NO3R2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NO3t7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NO3t7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NPHS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NPHS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD10" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD10" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD11" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD11" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD8" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD8" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTD9" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTD9" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP5" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP6" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP7" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPP8" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPP8" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPTP1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPTP1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTPTP2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTPTP2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_NTRIR2x" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_NTRIR2x" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_O2t" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_O2t" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OBTFL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OBTFL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OCBT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_OCBT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OCDCAt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OCDCAt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OCTDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OCTDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OHPBAT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_OHPBAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OHPHM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OHPHM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OMBZLM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OMBZLM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OMCDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OMCDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OMMBLHX" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OMMBLHX" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OMPDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OMPDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OMPHHX" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OMPHHX" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OP4ENH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OP4ENH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OPHBDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OPHBDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OPHHX" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OPHHX" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ORNDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ORNDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ORNTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ORNTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ORNabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_ORNabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_ORPT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_ORPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_OXGDC2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_OXGDC2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_P5CD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_P5CD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_P5CR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_P5CR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PACCOAL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PACCOAL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PANTS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PANTS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PAPA_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PAPA_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PAPPT3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PAPPT3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PAPSR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PAPSR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PASYN_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PASYN_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PDX5PO" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PDX5PO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PDX5PS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PDX5PS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PDXPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PDXPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PEAMNO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PEAMNO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PEPT_EC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PEPT_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PERD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PERD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PFK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PFK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PFK_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PFK_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PFL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PFL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGAMT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGAMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGCD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PGCD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGK" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PGL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGLYCP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PGLYCP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGM" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGMT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGPP_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PGPP_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PGSA_EC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PGSA_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PHETA1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PHETA1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PHEt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PHEt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PIabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PIabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PIt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PIt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PLIPA1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PLIPA1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PLIPA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PLIPA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PLIPA3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PLIPA3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PMANM" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PMANM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PMDPHT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PMDPHT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PMPK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PMPK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PNTK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PNTK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PNTOt4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PNTOt4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_POX" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_POX" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPAKr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PPAKr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPBNGS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPBNGS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPCDC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPCDC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPCK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPCK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPCSCT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPCSCT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPM" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PPM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPM2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PPM2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPNCL2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPNCL2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPND" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPND" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPNDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPNDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPPGO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPPGO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPPNDO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPPNDO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPPNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PPPNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PPTGS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PPTGS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRAGSr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PRAGSr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRAIS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRAIS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRAIi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRAIi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRAMPC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRAMPC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRASCS" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PRASCS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRATPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRATPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRFGS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRFGS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRMICIi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PRMICIi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PROD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PROD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PROabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PROabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PROt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PROt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PROt4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PROt4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PRPPS" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PRPPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PSCVT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PSCVT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PSD_EC" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PSD_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PSERT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PSERT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PSP_L" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PSP_L" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PSSA_EC" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PSSA_EC" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTA2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PTA2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTAr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PTAr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTPATi" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PTPATi" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTRCORNt7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PTRCORNt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTRCTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PTRCTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTRCabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PTRCabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PTRCt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PTRCt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP3" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP4" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP5" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP5" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP6" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP6" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PUNP7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PUNP7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYAM5PO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYAM5PO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYDAMK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYDAMK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYDXK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYDXK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYDXNK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYDXNK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYDXPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYDXPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_PYK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYNP2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PYNP2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_PYRt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_PYRt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_QULNS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_QULNS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBFK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RBFK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBFSa" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RBFSa" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBFSb" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RBFSb" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RBK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBK_L1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RBK_L1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RBP4E" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_RBP4E" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RHCCE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RHCCE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RIBabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RIBabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RMI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_RMI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RMK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RMK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RMNt" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RMNt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RMPA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_RMPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNDR1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNDR1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNDR2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNDR2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNDR3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNDR3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNDR4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNDR4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNTR1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNTR1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNTR2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNTR2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNTR3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNTR3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RNTR4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RNTR4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RPE" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_RPE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RPI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_RPI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_RZ5PP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_RZ5PP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_S7PI" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_S7PI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SADH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SADH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SADT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SADT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SBTPD" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SBTPD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SBTpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SBTpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SDPDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SDPDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SDPTA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SDPTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SELNPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SELNPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERASr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SERASr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERAT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SERAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERD_D" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SERD_D" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERD_L" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SERD_L" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SERt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SERt4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SERt4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SGDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SGDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SGSAD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SGSAD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHCHCS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SHCHCS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHCHD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SHCHD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHCHF" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SHCHF" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHK3Dr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SHK3Dr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHKK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SHKK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SHSL1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SHSL1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SOTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SOTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SPMDAT1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SPMDAT1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SPMDAT2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SPMDAT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SPMDabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SPMDabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SPMS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SPMS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SPODM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SPODM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SSALx" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SSALx" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SSALy" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SSALy" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCBZL" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCBZL" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCBZS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCBZS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCCabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCCabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCCt2_2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCCt2_2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCCt2_3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCCt2_3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCCt2b" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCCt2b" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCD1i" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCD1i" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCD4" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SUCD4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCFUMt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SUCFUMt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCOAS" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SUCOAS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SUCpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SUCpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SULR" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_SULR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_SULabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_SULabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TAGURr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TAGURr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TALA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TALA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TARTD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TARTD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TARTRt7" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TARTRt7" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TAUDO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TAUDO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TAURabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TAURabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDPADGAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDPADGAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDPAGTA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDPAGTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDPDRE" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDPDRE" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDPDRR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDPDRR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDPGDH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDPGDH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TDSK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TDSK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TGBPA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TGBPA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THD2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THD2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THMDt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_THMDt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THMabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THMabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRAr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_THRAr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THRD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRD_L" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THRD_L" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THRS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THRabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_THRt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THRt4" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THRt4" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_THZPSN" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_THZPSN" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TKT1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TKT1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TKT2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TKT2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMAOR1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMAOR1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMAOR1e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMAOR1e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMAOR2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMAOR2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMAOR2e" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMAOR2e" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMDK1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMDK1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMDPP" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TMDPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMKr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TMKr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMPKr" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TMPKr" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TMPPP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TMPPP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TPI" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TPI" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRDR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRDR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRE6PH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRE6PH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRE6PP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRE6PP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRE6PS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRE6PS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TREH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TREH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TREHe" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TREHe" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TREpts" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TREpts" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRPAS2" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TRPAS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRPS1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRPS1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRPS2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRPS2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRPS3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRPS3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRPt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TRPt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TRSAR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TRSAR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TSULabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TSULabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TTDCAt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_TTDCAt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TYRTA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TYRTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_TYRt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_TYRt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_U23GAAT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_U23GAAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAAGDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAAGDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UACMAMO" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UACMAMO" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAG2Ei" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAG2Ei" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAGAAT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_UAGAAT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAGCVT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAGCVT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAGDP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAGDP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAGPT3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAGPT3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAMAGS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAMAGS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAMAS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAMAS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UAPGR" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UAPGR" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UDCPDP" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UDCPDP" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UDCPDPS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UDCPDPS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UDPG4E" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_UDPG4E" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UDPGALM" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UDPGALM" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UDPGD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UDPGD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UGLT" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_UGLT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UGLYCH" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UGLYCH" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UGMDDS" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UGMDDS" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UHGADA" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UHGADA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UMPK" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_UMPK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UNK3" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UNK3" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UPP3MT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UPP3MT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UPP3S" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UPP3S" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UPPDC1" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UPPDC1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UPPRT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_UPPRT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_URAt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_URAt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_UREAt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_UREAt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_URIDK2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_URIDK2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_URIK2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_URIK2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_URIt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_URIt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_USHD" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_USHD" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_VALTA" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_VALTA" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_VALabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_VALabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_VALt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_VALt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_VPAMT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_VPAMT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_X5PL3E" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_X5PL3E" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XANt" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_XANt" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XANt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XANt2" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XPPT" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XPPT" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XTSNt2r" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_XTSNt2r" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XYLI1" fba:operation="greater" fba:value="-999999" />
                    <fba:constraint fba:reaction="R_XYLI1" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XYLI2i" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XYLI2i" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XYLK" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XYLK" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XYLabc" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XYLabc" fba:operation="less" fba:value="999999" />
                    <fba:constraint fba:reaction="R_XYLt2" fba:operation="greater" fba:value="0" />
                    <fba:constraint fba:reaction="R_XYLt2" fba:operation="less" fba:value="999999" />
                </fba:listOfConstraints>
                <fba:listOfObjectives fba:activeObjective="obj1">
                    <fba:objective id="obj1" fba:type="maximize">
                        <fba:listOfFluxes>
                            <fba:fluxObjective fba:reaction="R_BiomassEcoli" fba:coefficient="1" />
                        </fba:listOfFluxes>
                    </fba:objective>
                </fba:listOfObjectives>
            </fba:fluxBalance>
        </annotation>
        <listOfUnitDefinitions>
            <unitDefinition id="mmol_per_gDW_per_hr">
                <listOfUnits>
                    <unit kind="mole" scale="-3" />
                    <unit kind="gram" exponent="-1" />
                    <unit kind="second" exponent="-1" multiplier="0.00027777" />
                </listOfUnits>
            </unitDefinition>
        </listOfUnitDefinitions>
        <listOfCompartments>
            <compartment id="Cytosol" outside="Extraorganism" />
            <compartment id="Extraorganism" />
        </listOfCompartments>
        <listOfSpecies>
            <species id="M_10fthf_c" name="_10-Formyltetrahydrofolate_C20H21N7O7" compartment="Cytosol" charge="-2" />
            <species id="M_12dgr_EC_c" name="_1,2-Diacylglycerol  (E.coli)_C1836H3448O250" compartment="Cytosol" charge="0" />
            <species id="M_12ppd_S_c" name="(S)-Propane-1,2-diol_C3H8O2" compartment="Cytosol" charge="0" />
            <species id="M_12ppd_S_e" name="(S)-Propane-1,2-diol_C3H8O2" compartment="Extraorganism" charge="0" />
            <species id="M_13dpg_c" name="_3-Phospho-D-glyceroyl phosphate_C3H4O10P2" compartment="Cytosol" charge="-4" />
            <species id="M_15dap_c" name="_1,5-Diaminopentane_C5H16N2" compartment="Cytosol" charge="2" />
            <species id="M_15dap_e" name="_1,5-Diaminopentane_C5H16N2" compartment="Extraorganism" charge="2" />
            <species id="M_1pyr5c_c" name="_1-Pyrroline-5-carboxylate_C5H6NO2" compartment="Cytosol" charge="-1" />
            <species id="M_23ddhb_c" name="_2,3-Dihydro-2,3-dihydroxybenzoate_C7H7O4" compartment="Cytosol" charge="-1" />
            <species id="M_23dhb_c" name="_2,3-Dihydroxybenzoate_C7H5O4" compartment="Cytosol" charge="-1" />
            <species id="M_23dhba_c" name="(2,3-Dihydroxybenzoyl)adenylate_C17H16N5O10P" compartment="Cytosol" charge="-2" />
            <species id="M_23dhdp_c" name="_2,3-Dihydrodipicolinate_C7H5NO4" compartment="Cytosol" charge="-2" />
            <species id="M_23dhmb_c" name="(R)-2,3-Dihydroxy-3-methylbutanoate_C5H9O4" compartment="Cytosol" charge="-1" />
            <species id="M_23dhmp_c" name="(R)-2,3-Dihydroxy-3-methylpentanoate_C6H11O4" compartment="Cytosol" charge="-1" />
            <species id="M_23doguln_c" name="_2,3-Dioxo-L-gulonate_C6H7O7" compartment="Cytosol" charge="-1" />
            <species id="M_25aics_c" name="(S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P" compartment="Cytosol" charge="-4" />
            <species id="M_25dkglcn_c" name="_2,5-diketo-D-gluconate_C6H7O7" compartment="Cytosol" charge="-1" />
            <species id="M_25drapp_c" name="_2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate_C9H14N5O8P" compartment="Cytosol" charge="-2" />
            <species id="M_26dap_LL_c" name="LL-2,6-Diaminoheptanedioate_C7H14N2O4" compartment="Cytosol" charge="0" />
            <species id="M_26dap_M_c" name="meso-2,6-Diaminoheptanedioate_C7H14N2O4" compartment="Cytosol" charge="0" />
            <species id="M_26dap_M_e" name="meso-2,6-Diaminoheptanedioate_C7H14N2O4" compartment="Extraorganism" charge="0" />
            <species id="M_2ahbut_c" name="(S)-2-Aceto-2-hydroxybutanoate_C6H9O4" compartment="Cytosol" charge="-1" />
            <species id="M_2aobut_c" name="L-2-Amino-3-oxobutanoate_C4H7NO3" compartment="Cytosol" charge="0" />
            <species id="M_2cpr5p_c" name="_1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate_C12H13NO9P" compartment="Cytosol" charge="-3" />
            <species id="M_2dda7p_c" name="_2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate_C7H10O10P" compartment="Cytosol" charge="-3" />
            <species id="M_2ddg6p_c" name="_2-Dehydro-3-deoxy-D-gluconate 6-phosphate_C6H8O9P" compartment="Cytosol" charge="-3" />
            <species id="M_2ddglcn_c" name="_2-Dehydro-3-deoxy-D-gluconate_C6H9O6" compartment="Cytosol" charge="-1" />
            <species id="M_2ddglcn_e" name="_2-Dehydro-3-deoxy-D-gluconate_C6H9O6" compartment="Extraorganism" charge="-1" />
            <species id="M_2dh3dgal6p_c" name="_2-Dehydro-3-deoxy-D-galactonate 6-phosphate_C6H8O9P" compartment="Cytosol" charge="-3" />
            <species id="M_2dh3dgal_c" name="_2-Dehydro-3-deoxy-D-galactonate_C6H9O6" compartment="Cytosol" charge="-1" />
            <species id="M_2dhglcn_c" name="_2-Dehydro-D-gluconate_C6H9O7" compartment="Cytosol" charge="-1" />
            <species id="M_2dhguln_c" name="_2-Dehydro-L-gulonate_C6H9O7" compartment="Cytosol" charge="-1" />
            <species id="M_2dhp_c" name="_2-Dehydropantoate_C6H9O4" compartment="Cytosol" charge="-1" />
            <species id="M_2dmmq8_c" name="_2-Demethylmenaquinone 8_C50H70O2" compartment="Cytosol" charge="0" />
            <species id="M_2dmmql8_c" name="_2-Demethylmenaquinol 8_C50H72O2" compartment="Cytosol" charge="0" />
            <species id="M_2dr1p_c" name="_2-Deoxy-D-ribose 1-phosphate_C5H9O7P" compartment="Cytosol" charge="-2" />
            <species id="M_2dr5p_c" name="_2-Deoxy-D-ribose 5-phosphate_C5H9O7P" compartment="Cytosol" charge="-2" />
            <species id="M_2h3oppan_c" name="_2-Hydroxy-3-oxopropanoate_C3H3O4" compartment="Cytosol" charge="-1" />
            <species id="M_2ippm_c" name="_2-Isopropylmaleate_C7H8O4" compartment="Cytosol" charge="-2" />
            <species id="M_2kmb_c" name="_2-keto-4-methylthiobutyrate_C5H7O3S" compartment="Cytosol" charge="-1" />
            <species id="M_2mahmp_c" name="_2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate_C6H8N3O7P2" compartment="Cytosol" charge="-3" />
            <species id="M_2mcacn_c" name="cis-2-Methylaconitate_C7H5O6" compartment="Cytosol" charge="-3" />
            <species id="M_2mcit_c" name="_2-Methylcitrate_C7H7O7" compartment="Cytosol" charge="-3" />
            <species id="M_2me4p_c" name="_2-C-methyl-D-erythritol 4-phosphate_C5H11O7P" compartment="Cytosol" charge="-2" />
            <species id="M_2mecdp_c" name="_2-C-methyl-D-erythritol 2,4-cyclodiphosphate_C5H10O9P2" compartment="Cytosol" charge="-2" />
            <species id="M_2obut_c" name="_2-Oxobutanoate_C4H5O3" compartment="Cytosol" charge="-1" />
            <species id="M_2ohph_c" name="_2-Octaprenyl-6-hydroxyphenol_C46H70O2" compartment="Cytosol" charge="0" />
            <species id="M_2ombzl_c" name="_2-Octaprenyl-6-methoxy-1,4-benzoquinol_C47H72O3" compartment="Cytosol" charge="0" />
            <species id="M_2omhmbl_c" name="_2-Octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol_C48H74O4" compartment="Cytosol" charge="0" />
            <species id="M_2ommbl_c" name="_2-Octaprenyl-3-methyl-6-methoxy- 1,4-benzoquinol_C48H74O3" compartment="Cytosol" charge="0" />
            <species id="M_2omph_c" name="_2-Octaprenyl-6-methoxyphenol_C47H72O2" compartment="Cytosol" charge="0" />
            <species id="M_2oph_c" name="_2-Octaprenylphenol_C46H70O" compartment="Cytosol" charge="0" />
            <species id="M_2p4c2me_c" name="_2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol_C14H22N3O17P3" compartment="Cytosol" charge="-4" />
            <species id="M_2pg_c" name="D-Glycerate 2-phosphate_C3H4O7P" compartment="Cytosol" charge="-3" />
            <species id="M_2pglyc_c" name="_2-Phosphoglycolate_C2H2O6P" compartment="Cytosol" charge="-3" />
            <species id="M_2shchc_c" name="_2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate_C11H10O6" compartment="Cytosol" charge="-2" />
            <species id="M_34hpp_c" name="_3-(4-Hydroxyphenyl)pyruvate_C9H7O4" compartment="Cytosol" charge="-1" />
            <species id="M_3c2hmp_c" name="_3-Carboxy-2-hydroxy-4-methylpentanoate_C7H10O5" compartment="Cytosol" charge="-2" />
            <species id="M_3c3hmp_c" name="_3-Carboxy-3-hydroxy-4-methylpentanoate_C7H10O5" compartment="Cytosol" charge="-2" />
            <species id="M_3c4mop_c" name="_3-Carboxy-4-methyl-2-oxopentanoate_C7H8O5" compartment="Cytosol" charge="-2" />
            <species id="M_3dhguln_c" name="_3-Dehydro-L-gulonate_C6H9O7" compartment="Cytosol" charge="-1" />
            <species id="M_3dhgulnp_c" name="_3-keto-L-gulonate-6-phosphate_C6H8O10P" compartment="Cytosol" charge="-3" />
            <species id="M_3dhq_c" name="_3-Dehydroquinate_C7H9O6" compartment="Cytosol" charge="-1" />
            <species id="M_3dhsk_c" name="_3-Dehydroshikimate_C7H7O5" compartment="Cytosol" charge="-1" />
            <species id="M_3hcinnm_c" name="_3-hydroxycinnamic acid_C9H7O3" compartment="Cytosol" charge="-1" />
            <species id="M_3hcinnm_e" name="_3-hydroxycinnamic acid_C9H7O3" compartment="Extraorganism" charge="-1" />
            <species id="M_3hmrsACP_c" name="(R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]_C25H47N2O9PRS" compartment="Cytosol" charge="-1" />
            <species id="M_3hpppn_c" name="_3-(3-hydroxy-phenyl)propionate_C9H9O3" compartment="Cytosol" charge="-1" />
            <species id="M_3hpppn_e" name="_3-(3-hydroxy-phenyl)propionate_C9H9O3" compartment="Extraorganism" charge="-1" />
            <species id="M_3ig3p_c" name="C'-(3-Indolyl)-glycerol 3-phosphate_C11H12NO6P" compartment="Cytosol" charge="-2" />
            <species id="M_3mob_c" name="_3-Methyl-2-oxobutanoate_C5H7O3" compartment="Cytosol" charge="-1" />
            <species id="M_3mop_c" name="(S)-3-Methyl-2-oxopentanoate_C6H9O3" compartment="Cytosol" charge="-1" />
            <species id="M_3ophb_c" name="_3-Octaprenyl-4-hydroxybenzoate_C47H69O3" compartment="Cytosol" charge="-1" />
            <species id="M_3pg_c" name="_3-Phospho-D-glycerate_C3H4O7P" compartment="Cytosol" charge="-3" />
            <species id="M_3php_c" name="_3-Phosphohydroxypyruvate_C3H2O7P" compartment="Cytosol" charge="-3" />
            <species id="M_3psme_c" name="_5-O-(1-Carboxyvinyl)-3-phosphoshikimate_C10H9O10P" compartment="Cytosol" charge="-4" />
            <species id="M_4abut_c" name="_4-Aminobutanoate_C4H9NO2" compartment="Cytosol" charge="0" />
            <species id="M_4abut_e" name="_4-Aminobutanoate_C4H9NO2" compartment="Extraorganism" charge="0" />
            <species id="M_4abutn_c" name="_4-Aminobutanal_C4H10NO" compartment="Cytosol" charge="1" />
            <species id="M_4abz_c" name="_4-Aminobenzoate_C7H6NO2" compartment="Cytosol" charge="-1" />
            <species id="M_4adcho_c" name="_4-amino-4-deoxychorismate_C10H10NO5" compartment="Cytosol" charge="-1" />
            <species id="M_4ahmmp_c" name="_4-Amino-5-hydroxymethyl-2-methylpyrimidine_C6H9N3O" compartment="Cytosol" charge="0" />
            <species id="M_4ampm_c" name="_4-Amino-2-methyl-5-phosphomethylpyrimidine_C6H8N3O4P" compartment="Cytosol" charge="-2" />
            <species id="M_4c2me_c" name="_4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol_C14H23N3O14P2" compartment="Cytosol" charge="-2" />
            <species id="M_4h2opntn_c" name="_4-Hydroxy-2-oxopentanoate_C5H7O4" compartment="Cytosol" charge="-1" />
            <species id="M_4hba_c" name="_4-Hydroxy-benzyl alcohol_C7H8O2" compartment="Cytosol" charge="0" />
            <species id="M_4hbz_c" name="_4-Hydroxybenzoate_C7H5O3" compartment="Cytosol" charge="-1" />
            <species id="M_4hthr_c" name="_4-Hydroxy-L-threonine_C4H9NO4" compartment="Cytosol" charge="0" />
            <species id="M_4mhetz_c" name="_4-Methyl-5-(2-hydroxyethyl)-thiazole_C6H9NOS" compartment="Cytosol" charge="0" />
            <species id="M_4mop_c" name="_4-Methyl-2-oxopentanoate_C6H9O3" compartment="Cytosol" charge="-1" />
            <species id="M_4mpetz_c" name="_4-Methyl-5-(2-phosphoethyl)-thiazole_C6H8NO4PS" compartment="Cytosol" charge="-2" />
            <species id="M_4pasp_c" name="_4-Phospho-L-aspartate_C4H6NO7P" compartment="Cytosol" charge="-2" />
            <species id="M_4per_c" name="_4-Phospho-D-erythronate_C4H6O8P" compartment="Cytosol" charge="-3" />
            <species id="M_4ppan_c" name="D-4'-Phosphopantothenate_C9H15NO8P" compartment="Cytosol" charge="-3" />
            <species id="M_4ppcys_c" name="N-((R)-4-Phosphopantothenoyl)-L-cysteine_C12H20N2O9PS" compartment="Cytosol" charge="-3" />
            <species id="M_4r5au_c" name="_4-(1-D-Ribitylamino)-5-aminouracil_C9H16N4O6" compartment="Cytosol" charge="0" />
            <species id="M_5aizc_c" name="_5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P" compartment="Cytosol" charge="-3" />
            <species id="M_5aop_c" name="_5-Amino-4-oxopentanoate_C5H9NO3" compartment="Cytosol" charge="0" />
            <species id="M_5aprbu_c" name="_5-Amino-6-(5'-phosphoribitylamino)uracil_C9H15N4O9P" compartment="Cytosol" charge="-2" />
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            <species id="M_gal_b" name="D-Galactose_C6H12O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_galct_D_b" name="D-Galactarate_C6H8O8" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_galctn_D_b" name="D-Galactonate_C6H11O7" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_galt_b" name="Galactitol_C6H14O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_galur_b" name="D-Galacturonate_C6H9O7" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_gam_b" name="D-Glucosamine_C6H14NO5" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_gbbtn_b" name="gamma-butyrobetaine_C7H15NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glc_D_b" name="D-Glucose_C6H12O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glcn_b" name="D-Gluconate_C6H11O7" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_glcr_b" name="D-Glucarate_C6H8O8" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_glcur_b" name="D-Glucuronate_C6H9O7" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_gln_L_b" name="L-Glutamine_C5H10N2O3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glu_L_b" name="L-Glutamate_C5H8NO4" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_gly_b" name="Glycine_C2H5NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glyald_b" name="D-Glyceraldehyde_C3H6O3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glyb_b" name="Glycine betaine_C5H11NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glyc3p_b" name="Glycerol 3-phosphate_C3H7O6P" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_glyc_b" name="Glycerol_C3H8O3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_glyclt_b" name="Glycolate_C2H3O3" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_gsn_b" name="Guanosine_C10H13N5O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_gua_b" name="Guanine_C5H5N5O" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_h2o_b" name="H2O_H2O" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_h_b" name="H+_H" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_hdca_b" name="Hexadecanoate (n-C16:0)_C16H31O2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_his_L_b" name="L-Histidine_C6H9N3O2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_hxan_b" name="Hypoxanthine_C5H4N4O" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_idon_L_b" name="L-Idonate_C6H11O7" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_ile_L_b" name="L-Isoleucine_C6H13NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_indole_b" name="Indole_C8H7N" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ins_b" name="Inosine_C10H12N4O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_k_b" name="potassium_K" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_lac_D_b" name="D-Lactate_C3H5O3" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_lac_L_b" name="L-Lactate_C3H5O3" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_lcts_b" name="Lactose_C12H22O11" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_leu_L_b" name="L-Leucine_C6H13NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_lys_L_b" name="L-Lysine_C6H15N2O2" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_mal_L_b" name="L-Malate_C4H4O5" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_malt_b" name="Maltose_C12H22O11" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_malthx_b" name="Maltohexaose_C36H62O31" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_maltpt_b" name="Maltopentaose_C30H52O26" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_malttr_b" name="Maltotriose_C18H32O16" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_maltttr_b" name="Maltotetraose_C24H42O21" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_man6p_b" name="D-Mannose 6-phosphate_C6H11O9P" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_man_b" name="D-Mannose_C6H12O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_melib_b" name="Melibiose_C12H22O11" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_met_D_b" name="D-Methionine_C5H10NO2S" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_met_L_b" name="L-Methionine_C5H11NO2S" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_mnl_b" name="D-Mannitol_C6H14O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_na1_b" name="Sodium_Na" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_nac_b" name="Nicotinate_C6H4NO2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_nad_b" name="Nicotinamide adenine dinucleotide_C21H26N7O14P2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_nh4_b" name="Ammonium_H4N" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_nmn_b" name="NMN_C11H14N2O8P" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_no2_b" name="Nitrite_NO2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_no3_b" name="Nitrate_NO3" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_o2_b" name="O2_O2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ocdca_b" name="octadecanoate (n-C18:0)_C18H35O2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_orn_b" name="Ornithine_C5H13N2O2" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_phe_L_b" name="L-Phenylalanine_C9H11NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_pi_b" name="Phosphate_HO4P" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_pnto_R_b" name="(R)-Pantothenate_C9H16NO5" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_pppn_b" name="Phenylpropanoate_C9H9O2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_pro_L_b" name="L-Proline_C5H9NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ptrc_b" name="Putrescine_C4H14N2" compartment="Extraorganism" boundaryCondition="true" charge="2" />
            <species id="M_pyr_b" name="Pyruvate_C3H3O3" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_rib_D_b" name="D-Ribose_C5H10O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_rmn_b" name="L-Rhamnose_C6H12O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_sbt_D_b" name="D-Sorbitol_C6H14O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ser_D_b" name="D-Serine_C3H7NO3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ser_L_b" name="L-Serine_C3H7NO3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_so4_b" name="Sulfate_O4S" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_spmd_b" name="Spermidine_C7H22N3" compartment="Extraorganism" boundaryCondition="true" charge="3" />
            <species id="M_succ_b" name="Succinate_C4H4O4" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_sucr_b" name="Sucrose_C12H22O11" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_tartr_L_b" name="L-tartrate_C4H4O6" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_taur_b" name="Taurine_C2H7NO3S" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_thm_b" name="Thiamin_C12H17N4OS" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_thr_L_b" name="L-Threonine_C4H9NO3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_thymd_b" name="Thymidine_C10H14N2O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_tma_b" name="trimethylamine_C3H10N" compartment="Extraorganism" boundaryCondition="true" charge="1" />
            <species id="M_tmao_b" name="Trimethylamine N-oxide_C3H9NO" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_tre_b" name="Trehalose_C12H22O11" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_trp_L_b" name="L-Tryptophan_C11H12N2O2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_tsul_b" name="Thiosulfate_O3S2" compartment="Extraorganism" boundaryCondition="true" charge="-2" />
            <species id="M_ttdca_b" name="tetradecanoate (n-C14:0)_C14H27O2" compartment="Extraorganism" boundaryCondition="true" charge="-1" />
            <species id="M_tyr_L_b" name="L-Tyrosine_C9H11NO3" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_ura_b" name="Uracil_C4H4N2O2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_urea_b" name="Urea_CH4N2O" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_uri_b" name="Uridine_C9H12N2O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_val_L_b" name="L-Valine_C5H11NO2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_xan_b" name="Xanthine_C5H4N4O2" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_xtsn_b" name="Xanthosine_C10H12N4O6" compartment="Extraorganism" boundaryCondition="true" charge="0" />
            <species id="M_xyl_D_b" name="D-Xylose_C5H10O5" compartment="Extraorganism" boundaryCondition="true" charge="0" />
        </listOfSpecies>
        <listOfReactions>
            <reaction id="R_12PPDt" name="S-Propane-1,2-diol facilitated transport">
                <notes>
                    <html:p>Abbreviation: R_12PPDt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: _12ppd-S[e] &lt;==&gt; 12ppd-S[c]</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_12ppd_S_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_12ppd_S_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_2DGLCNRx" name="_2-dehydro-D-gluconate reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_2DGLCNRx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dhglcn + h + nadh --&gt; glcn + nad</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dhglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_2DGLCNRy" name="_2-dehydro-D-gluconate reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_2DGLCNRy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.215</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dhglcn + h + nadph --&gt; glcn + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dhglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_2DGULRx" name="_2-dehydro-L-gulonate reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_2DGULRx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dhguln + h + nadh --&gt; idon-L + nad</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dhguln_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_idon_L_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_2DGULRy" name="_2-dehydro-L-gulonate reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_2DGULRy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dhguln + h + nadph --&gt; idon-L + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dhguln_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_idon_L_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_3HCINNMH" name="_3-hydroxycinnamate hydroxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_3HCINNMH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 3hcinnm + h + nadh + o2 --&gt; dhcinnm + h2o + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- see PMID:9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0347#ABBREVIATION:mhpA#ECNUMBERS:1.14.13.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-(3-hydroxy-phenyl)propionate hydroxylase#ABBREVIATION:MhpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0347)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hcinnm_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhcinnm_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_3HPPPNH" name="_3-(3-hydroxy-phenyl)propionate hydroxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_3HPPPNH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 3hpppn + h + nadh + o2 --&gt; dhpppn + h2o + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- see PMID 9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0347#ABBREVIATION:mhpA#ECNUMBERS:1.14.13.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-(3-hydroxy-phenyl)propionate hydroxylase#ABBREVIATION:MhpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0347)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hpppn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhpppn_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_4HTHRS" name="_4-Hydroxy-L-threonine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_4HTHRS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + phthr --&gt; 4hthr + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0004#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Threonine synthase#ABBREVIATION:ThrC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0004)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_phthr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4hthr_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_5DGLCNR" name="_5-dehydro-D-gluconate reductase">
                <notes>
                    <html:p>Abbreviation: R_5DGLCNR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.69</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 5dglcn + h + nadph &lt;==&gt; glcn + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4266#ABBREVIATION:idnO#ECNUMBERS:1.1.1.69#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5-keto-D-gluconate reductase#ABBREVIATION:IdnO#</html:p>
                    <html:p>GENE ASSOCIATION: (b4266)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5dglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_A5PISO" name="arabinose-5-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_A5PISO</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 5.3.1.13</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : ru5p-D &lt;==&gt; ara5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ru5p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ara5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AACPS1" name="acyl-[acyl-carrier-protein] synthetase (n-C14:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AACPS1</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ACP + atp + ttdca --&gt; amp + myrsACP + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2836#ABBREVIATION:aas#ECNUMBERS:2.3.1.40,-!-,6.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acyl-ACp synthase#ABBREVIATION:Aas#</html:p>
                    <html:p>GENE ASSOCIATION: (b2836)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ttdca_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_myrsACP_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AACPS2" name="acyl-[acyl-carrier-protein] synthetase  (n-C14:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AACPS2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ACP + atp + ttdcea --&gt; amp + ppi + tdeACP</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2836#ABBREVIATION:aas#ECNUMBERS:2.3.1.40,-!-,6.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acyl-ACp synthase#ABBREVIATION:Aas#</html:p>
                    <html:p>GENE ASSOCIATION: (b2836)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ttdcea_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_tdeACP_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AACPS3" name="acyl-[acyl-carrier-protein] synthetase  (n-C16:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AACPS3</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ACP + atp + hdca --&gt; amp + palmACP + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2836#ABBREVIATION:aas#ECNUMBERS:2.3.1.40,-!-,6.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acyl-ACp synthase#ABBREVIATION:Aas#</html:p>
                    <html:p>GENE ASSOCIATION: (b2836)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_hdca_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_palmACP_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AACPS4" name="acyl-[acyl-carrier-protein] synthetase  (n-C16:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AACPS4</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ACP + atp + hdcea --&gt; amp + hdeACP + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2836#ABBREVIATION:aas#ECNUMBERS:2.3.1.40,-!-,6.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acyl-ACp synthase#ABBREVIATION:Aas#</html:p>
                    <html:p>GENE ASSOCIATION: (b2836)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_hdcea_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_hdeACP_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AACPS5" name="acyl-[acyl-carrier-protein] synthetase  (n-C18:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AACPS5</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ACP + atp + ocdcea --&gt; amp + octeACP + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2836#ABBREVIATION:aas#ECNUMBERS:2.3.1.40,-!-,6.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acyl-ACp synthase#ABBREVIATION:Aas#</html:p>
                    <html:p>GENE ASSOCIATION: (b2836)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ocdcea_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_octeACP_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AADDGT" name="dTDP-N-4-acetamido-4,6-dideoxy-D-galactose transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AADDGT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dtdp4aaddg + unagamu --&gt; dtdp + h + unagamuf</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3793#ABBREVIATION:wzyE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-N-4-acetamido-4,6-dideoxy-D-galactose transferase#ABBREVIATION:WecF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3793)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtdp4aaddg_c" />
                    <speciesReference species="M_unagamu_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtdp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_unagamuf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AB6PGH" name="Arbutin 6-phosphate glucohydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AB6PGH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.1.86</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : arbt6p + h2o --&gt; g6p + hqn</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg R05133)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2901#ABBREVIATION:bglA#ECNUMBERS:3.2.1.86#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_6-phospho-beta-glucosidase A#ABBREVIATION:BglA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2901)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arbt6p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_hqn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ABTA" name="_4-aminobutyrate transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ABTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.19</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 4abut + akg --&gt; glu-L + sucsal</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1302#ABBREVIATION:puuE#ECNUMBERS:2.6.1.19#</html:p>
                    <html:p>LOCUS:b2662#ABBREVIATION:gabT#ECNUMBERS:2.6.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_4-aminobutyrate aminotransferase I#ABBREVIATION:GabT#</html:p>
                    <html:p>NAME:_4-aminobutyrate aminotransferase II#ABBREVIATION:PuuE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2662) or (b1302)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abut_c" />
                    <speciesReference species="M_akg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_sucsal_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ABUTD" name="Aminobutyraldehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ABUTD</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.2.1.19</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 4abutn + h2o + nad --&gt; 4abut + (2) h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abutn_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abut_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ABUTt2" name="_4-aminobutyrate transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ABUTt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: _4abut[e] + h[e] --&gt; 4abut[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2663#ABBREVIATION:gabP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, GABA proton symport#ABBREVIATION:GabP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2663)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abut_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abut_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACACCT" name="acetyl-CoA:acetoacetyl-CoA transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACACCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : acac + accoa --&gt; aacoa + ac</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2221#ABBREVIATION:atoD#ECNUMBERS:2.8.3.8#</html:p>
                    <html:p>LOCUS:b2222#ABBREVIATION:atoA#ECNUMBERS:2.8.3.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetyl-CoA: acetoacetyl -CoA transferase#ABBREVIATION:AtoADec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2222 and b2221)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acac_c" />
                    <speciesReference species="M_accoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aacoa_c" />
                    <speciesReference species="M_ac_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACACT1r" name="acetyl-CoA C-acetyltransferase">
                <notes>
                    <html:p>Abbreviation: R_ACACT1r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.9</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : (2) accoa &lt;==&gt; aacoa + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible form of ACACT1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2224#ABBREVIATION:atoB#ECNUMBERS:2.3.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetyl-CoA acetyltransferase#ABBREVIATION:AtoBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2224)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aacoa_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACACt2" name="acetoacetate transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ACACt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: acac[e] + h[e] &lt;==&gt; acac[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>originally named AACTP
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2223#ABBREVIATION:atoE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative short chain fatty acid transporter#ABBREVIATION:AtoE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2223)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acac_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acac_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACALDi" name="acetaldehyde dehydrogenase (acetylating)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACALDi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.10</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : acald + coa + nad --&gt; accoa + h + nadh</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- irreversible form of ACALD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0351#ABBREVIATION:mhpF#ECNUMBERS:1.2.1.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetaldehyde-CoA dehydrogenase II#ABBREVIATION:MhpF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0351)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACALDt" name="acetaldehyde reversible transport">
                <notes>
                    <html:p>Abbreviation: R_ACALDt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: acald[e] &lt;==&gt; acald[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acald_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACBIPGT" name="Adenosyl cobinamide phosphate guanyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACBIPGT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : adocbip + gtp + h --&gt; agdpcbi + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg Rxn R05222)
EC 2.7.7.62</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1993#ABBREVIATION:cobU#ECNUMBERS:?#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Cobinamide kinase and cobinamide phosphate guanyltransferase#ABBREVIATION:CobU#</html:p>
                    <html:p>GENE ASSOCIATION: (b1993)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adocbip_c" />
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_agdpcbi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACCOACr" name="acetyl-CoA carboxylase, reversible reaction">
                <notes>
                    <html:p>Abbreviation: R_ACCOACr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.4.1.2</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + atp + hco3 &lt;==&gt; adp + h + malcoa + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0185#ABBREVIATION:accA#ECNUMBERS:6.4.1.2#</html:p>
                    <html:p>LOCUS:b2316#ABBREVIATION:accD#ECNUMBERS:6.4.1.2#</html:p>
                    <html:p>LOCUS:b3255#ABBREVIATION:accB#</html:p>
                    <html:p>LOCUS:b3256#ABBREVIATION:accC#ECNUMBERS:6.3.4.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:AcetylCoA carboxylase#ABBREVIATION:Acc#</html:p>
                    <html:p>GENE ASSOCIATION: (b0185 and b3255 and b3256 and b2316)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_hco3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malcoa_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACCOAL" name="acetate-CoA ligase (ADP-forming)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACCOAL</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.2.1.13</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + coa + ppa --&gt; adp + pi + ppcoa</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR- also acts on propanoate</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0335#ABBREVIATION:prpE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Propionyl-CoA synthetase #ABBREVIATION:PrpE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0335)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_ppa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppcoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACGAMT" name="UDP-N-acetylglucosamine:undecaprenylphosphate N-acetylglucosamine -1-phosphate transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACGAMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : uacgam + udcpp --&gt; ump + unaga</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3784#ABBREVIATION:rfe#ECNUMBERS:2.4.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylglucosamine:undecaprenylphosphate N-acetylglucosamine -1-phosphate transferase#ABBREVIATION:WecA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3784)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uacgam_c" />
                    <speciesReference species="M_udcpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ump_c" />
                    <speciesReference species="M_unaga_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACGApts" name="N-Acetyl-D-glucosamine transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACGApts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: acgam[e] + pep[c] --&gt; acgam6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0679#ABBREVIATION:nagE#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1101#ABBREVIATION:ptsG#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2417#ABBREVIATION:crr#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, Glucose/Trehalose/Maltose IIA#ABBREVIATION:Crr#</html:p>
                    <html:p>NAME:PTS, glucose IIBC#ABBREVIATION:PtsG#</html:p>
                    <html:p>NAME:PTS, N-acetylglucosamine IIABC#ABBREVIATION:NagE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2417) and (b2416) and (b1101) or (b2415) and (b2416) and (b0679)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acgam_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acgam6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACGK" name="acetylglutamate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACGK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.8</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : acglu + atp --&gt; acg5p + adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3959#ABBREVIATION:argB#ECNUMBERS:2.7.2.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetylglutamate kinase#ABBREVIATION:ArgB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3959)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acglu_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acg5p_c" />
                    <speciesReference species="M_adp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACGS" name="N-acetylglutamate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACGS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.1</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + glu-L --&gt; acglu + coa + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2818#ABBREVIATION:argA#ECNUMBERS:2.3.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglutamate synthase#ABBREVIATION:ArgA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2818)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acglu_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACHBS" name="_2-aceto-2-hydroxybutanoate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACHBS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 2obut + h + pyr --&gt; 2ahbut + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- I think the EC is 4.1.3.18</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0077#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b0078#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3670#ABBREVIATION:ilvN#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3671#ABBREVIATION:ilvB#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3767#ABBREVIATION:ilvG_1#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3768#ABBREVIATION:ilvG_2#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3769#ABBREVIATION:ilvM#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetolactate synthase I#ABBREVIATION:IlvB#</html:p>
                    <html:p>NAME:acetolatcate synthase II#ABBREVIATION:IlvG#</html:p>
                    <html:p>NAME:acetolactate synthase III#ABBREVIATION:IlvH#</html:p>
                    <html:p>GENE ASSOCIATION: (b3670 and b3671) or (b0077 and b0078) or (b3768 and b3769 and b3767)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2obut_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ahbut_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACKr" name="acetate kinase">
                <notes>
                    <html:p>Abbreviation: R_ACKr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.1</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : ac + atp &lt;==&gt; actp + adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- This is the reversible form of ACK.  The reaction already exists in the database, but it is listed as ACK_do not use.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1849#ABBREVIATION:purT#ECNUMBERS:2.7.2.1#</html:p>
                    <html:p>LOCUS:b2296#ABBREVIATION:ackA#ECNUMBERS:2.7.2.-,-!-,2.7.2.1#</html:p>
                    <html:p>LOCUS:b3115#ABBREVIATION:tdcD#ECNUMBERS:2.7.2.1,-!-,2.7.2.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Acetate kinase#ABBREVIATION:AckA#</html:p>
                    <html:p>NAME:phosribosylglycinamide formyltransferase II#ABBREVIATION:PurT#</html:p>
                    <html:p>NAME:propionate kinase and acetate kinase II#ABBREVIATION:TdcD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2296) or (b3115) or (b1849)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_actp_c" />
                    <speciesReference species="M_adp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACLS" name="acetolactate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACLS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.18</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : h + (2) pyr --&gt; alac-S + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>A flavoprotein. Requires thiamine diphosphate; also catalyses the formation of 2-aceto-2-hydroxybutanoate (see ACHBS).
Also EC 2.2.1.6 - NCD
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0077#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b0078#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3670#ABBREVIATION:ilvN#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3671#ABBREVIATION:ilvB#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3767#ABBREVIATION:ilvG_1#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3768#ABBREVIATION:ilvG_2#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>LOCUS:b3769#ABBREVIATION:ilvM#ECNUMBERS:2.2.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetolactate synthase I#ABBREVIATION:IlvB#</html:p>
                    <html:p>NAME:acetolatcate synthase II#ABBREVIATION:IlvG#</html:p>
                    <html:p>NAME:acetolactate synthase III#ABBREVIATION:IlvH#</html:p>
                    <html:p>GENE ASSOCIATION: (b3670 and b3671) or (b0077 and b0078) or (b3768 and b3769 and b3767)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_alac_S_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACMAMUT" name="UDP-N-acetyl-D-mannosaminuronic acid transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACMAMUT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : uacmamu + unaga --&gt; h + udp + unagamu</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3794#ABBREVIATION:rffM#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetyl-D-mannosaminuronate transferase#ABBREVIATION:WecG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3794)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uacmamu_c" />
                    <speciesReference species="M_unaga_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_udp_c" />
                    <speciesReference species="M_unagamu_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACMANApts" name="N-acetyl-D-mannosamine transport via PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACMANApts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: acmana[e] + pep[c] --&gt; acmanap[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1817#ABBREVIATION:manX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1818#ABBREVIATION:manY#</html:p>
                    <html:p>LOCUS:b1819#ABBREVIATION:manZ#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, mannose IIA#ABBREVIATION:ManX#</html:p>
                    <html:p>NAME:PTS, mannose IIC#ABBREVIATION:ManY#</html:p>
                    <html:p>NAME:PTS, mannose IID#ABBREVIATION:ManZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b1818) and (b1817) and (b1819)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acmana_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acmanap_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACNAMt2" name="N-acetylneuraminate proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACNAMt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: acnam[e] + h[e] --&gt; acnam[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3224#ABBREVIATION:nanT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, sialic acid H symporter#ABBREVIATION:NanT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3224)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acnam_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acnam_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACNML" name="N-Acetylneuraminate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACNML</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.3</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : acnam --&gt; acmana + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3225#ABBREVIATION:nanA#ECNUMBERS:4.1.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylneuraminate lyase#ABBREVIATION:NanA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3225)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acnam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acmana_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACOATA" name="Acetyl-CoA ACP transacylase">
                <notes>
                    <html:p>Abbreviation: R_ACOATA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.38</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : ACP + accoa &lt;==&gt; acACP + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
rxn is now charge balanced; removed h - NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1091#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1091)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_accoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acACP_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACODA" name="acetylornithine deacetylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACODA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.16</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : acorn + h2o --&gt; ac + orn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3957#ABBREVIATION:argE#ECNUMBERS:3.5.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetylornithine deacetylase#ABBREVIATION:ArgE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3957)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acorn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_orn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACONMT" name="Trans-aconitate methyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACONMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : acon-T + amet --&gt; aconm + ahcys</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1519#ABBREVIATION:tam#ECNUMBERS:2.1.1.144#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trans-aconitate methyltransferase#ABBREVIATION:Tam#</html:p>
                    <html:p>GENE ASSOCIATION: (b1519)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acon_T_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aconm_c" />
                    <speciesReference species="M_ahcys_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACONT" name="aconitase">
                <notes>
                    <html:p>Abbreviation: R_ACONT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.3</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : cit &lt;==&gt; icit</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0118#ABBREVIATION:acnB#ECNUMBERS:4.2.1.3,-!-,4.2.1.99#</html:p>
                    <html:p>LOCUS:b1276#ABBREVIATION:acnA#ECNUMBERS:4.2.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aconitase A#ABBREVIATION:AcnA#</html:p>
                    <html:p>NAME:aconitase B#ABBREVIATION:AcnB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1276) or (b0118)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cit_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_icit_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACOTA" name="acetylornithine transaminase">
                <notes>
                    <html:p>Abbreviation: R_ACOTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.11</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : acorn + akg &lt;==&gt; acg5sa + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3359#ABBREVIATION:argD#ECNUMBERS:2.6.1.11,-!-,2.6.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetylornithine transaminase#ABBREVIATION:ArgD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3359)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acorn_c" />
                    <speciesReference species="M_akg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acg5sa_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACPS1" name="acyl-carrier protein synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACPS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.8.7</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : apoACP + coa --&gt; ACP + h + pap</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2563#ABBREVIATION:acpS#ECNUMBERS:2.7.8.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Holo-acp synthase#ABBREVIATION:AcpS#</html:p>
                    <html:p>GENE ASSOCIATION: (b2563)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_apoACP_c" />
                    <speciesReference species="M_coa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pap_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACS" name="acetyl-CoA synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ACS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.2.1.1</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : ac + atp + coa --&gt; accoa + amp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4069#ABBREVIATION:acs#ECNUMBERS:6.2.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetyl-CoA synthetase#ABBREVIATION:Acs#</html:p>
                    <html:p>GENE ASSOCIATION: (b4069)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ACt2r" name="acetate reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ACt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: ac[e] + h[e] &lt;==&gt; ac[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ac_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADA" name="Adenosine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.4</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : adn + h + h2o --&gt; ins + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Added EC- JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1623#ABBREVIATION:add#ECNUMBERS:3.5.4.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:adenosine deaminase#ABBREVIATION:Add#</html:p>
                    <html:p>GENE ASSOCIATION: (b1623)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ins_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADCL" name="_4-aminobenzoate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADCL</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4adcho --&gt; 4abz + h + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Not in IUBMB. No EC
EC: 4.1.3.38 IT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1096#ABBREVIATION:pabC#ECNUMBERS:4.1.3.38#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aminodeoxychorismate lyase#ABBREVIATION:PabC#</html:p>
                    <html:p>GENE ASSOCIATION: (b1096)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4adcho_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abz_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADCS" name="_4-amino-4-deoxychorismate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADCS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : chor + gln-L --&gt; 4adcho + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Not in IUBMB. No EC</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1812#ABBREVIATION:pabB#ECNUMBERS:6.3.5.8#</html:p>
                    <html:p>LOCUS:b3360#ABBREVIATION:pabA#ECNUMBERS:6.3.5.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:p-aminobenzoate synthetase, component II#ABBREVIATION:PabA#</html:p>
                    <html:p>NAME:p-aminobenzoate synthetase, component I#ABBREVIATION:PabBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3360) and (b1812)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chor_c" />
                    <speciesReference species="M_gln_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4adcho_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADD" name="adenine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ade + h + h2o --&gt; hxan + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>note:  reaction also occures spontaneously - oxidative deaminination  (MKA)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3665#ABBREVIATION:ade#ECNUMBERS:3.5.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative adenine deaminase#ABBREVIATION:YicP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3665)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hxan_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADEt2r" name="adenine transport via proton symport (reversible)">
                <notes>
                    <html:p>Abbreviation: R_ADEt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: ade[e] + h[e] &lt;==&gt; ade[c] + h[c]</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3654#ABBREVIATION:yicE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative puring/xanthine transport, NCS2#ABBREVIATION:YicE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3654)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ade_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADHEr" name="Acetaldehyde dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_ADHEr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + (2) h + (2) nadh &lt;==&gt; coa + etoh + (2) nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - added the reversible form of ADHE2.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1241#ABBREVIATION:adhE#ECNUMBERS:1.2.1.10,-!-,1.1.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Acetaldehyde-CoA dehydrogenase#ABBREVIATION:AdhE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1241)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_etoh_c" />
                    <speciesReference species="M_nad_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADK1" name="adenylate kinase">
                <notes>
                    <html:p>Abbreviation: R_ADK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.3</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : amp + atp &lt;==&gt; (2) adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Inorganic triphosphate can also act as donor</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0474#ABBREVIATION:adk#ECNUMBERS:2.7.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate kinase#ABBREVIATION:Adk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0474)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADK3" name="adentylate kinase (GTP)">
                <notes>
                    <html:p>Abbreviation: R_ADK3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : amp + gtp &lt;==&gt; adp + gdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0474#ABBREVIATION:adk#ECNUMBERS:2.7.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate kinase#ABBREVIATION:Adk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0474)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_gtp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADK4" name="adentylate kinase (ITP)">
                <notes>
                    <html:p>Abbreviation: R_ADK4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : amp + itp &lt;==&gt; adp + idp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0474#ABBREVIATION:adk#ECNUMBERS:2.7.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate kinase#ABBREVIATION:Adk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0474)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_itp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_idp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADMDCr" name="Adenosylmethionine decarboxylase">
                <notes>
                    <html:p>Abbreviation: R_ADMDCr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.50</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : amet + h &lt;==&gt; ametam + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of ADMDC</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0120#ABBREVIATION:speD#ECNUMBERS:4.1.1.50#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:S-adenosylmethionine decarboxylase#ABBREVIATION:SpeD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0120)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amet_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ametam_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADNCYC" name="adenylate cyclase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADNCYC</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 4.6.1.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp --&gt; camp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3806#ABBREVIATION:cyaA#ECNUMBERS:4.6.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate cyclase#ABBREVIATION:CyaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3806)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_camp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADNK1" name="adenosine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADNK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.20</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : adn + atp --&gt; adp + amp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>_2-Aminoadenosine can also act as acceptor</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0474#ABBREVIATION:adk#ECNUMBERS:2.7.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate kinase#ABBREVIATION:Adk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0474)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADNt2r" name="adenosine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_ADNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: adn[e] + h[e] &lt;==&gt; adn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADOCBIK" name="Adenosyl cobinamide kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADOCBIK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : adocbi + atp --&gt; adocbip + adp + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg Rxn R05221)
EC 2.7.1.156</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1993#ABBREVIATION:cobU#ECNUMBERS:?#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Cobinamide kinase and cobinamide phosphate guanyltransferase#ABBREVIATION:CobU#</html:p>
                    <html:p>GENE ASSOCIATION: (b1993)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adocbi_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adocbip_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADOCBLS" name="Adenosylcobalamin 5'-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADOCBLS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : agdpcbi + rdmbzi --&gt; adocbl + gmp + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg RXN R05223)
EC 2.7.8.26</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1992#ABBREVIATION:cobS#ECNUMBERS:2.-.-.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cobalamine 5'-phosphate synthase#ABBREVIATION:CobS#</html:p>
                    <html:p>GENE ASSOCIATION: (b1992)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agdpcbi_c" />
                    <speciesReference species="M_rdmbzi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adocbl_c" />
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADPT" name="adenine phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.7</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ade + prpp --&gt; amp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0469#ABBREVIATION:apt#ECNUMBERS:2.4.2.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenine phosphoribosyltransferase#ABBREVIATION:Apt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0469)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADSK" name="adenylyl-sulfate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADSK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.25</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : aps + atp --&gt; adp + h + paps</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2750#ABBREVIATION:cysC#ECNUMBERS:2.7.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:adenosine 5'-phosphosulfate kinase#ABBREVIATION:CysC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2750)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_aps_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_paps_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADSL1r" name="adenylsuccinate lyase">
                <notes>
                    <html:p>Abbreviation: R_ADSL1r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.2.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : dcamp &lt;==&gt; amp + fum</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of ADSL1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1131#ABBREVIATION:purB#ECNUMBERS:4.3.2.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylosuccinate lyase#ABBREVIATION:PurB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1131)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dcamp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_fum_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADSL2r" name="adenylosuccinate lyase">
                <notes>
                    <html:p>Abbreviation: R_ADSL2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.2.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : 25aics &lt;==&gt; aicar + fum</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of ADSL2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1131#ABBREVIATION:purB#ECNUMBERS:4.3.2.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylosuccinate lyase#ABBREVIATION:PurB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1131)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_25aics_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aicar_c" />
                    <speciesReference species="M_fum_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ADSS" name="adenylosuccinate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ADSS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.4.4</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + gtp + imp --&gt; dcamp + gdp + (2) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4177#ABBREVIATION:purA#ECNUMBERS:6.3.4.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylosuccinate synthetase#ABBREVIATION:PurA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4177)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_imp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcamp_c" />
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AGDC" name="N-acetylglucosamine-6-phosphate deacetylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AGDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : acgam6p + h2o --&gt; ac + gam6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>acetylglucosamine phosphate deacetylase; 
acetylaminodeoxyglucosephosphate acetylhydrolase; 
2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0677#ABBREVIATION:nagA#ECNUMBERS:3.5.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglucosamine-6-phosphate deacetylase#ABBREVIATION:NagA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0677)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acgam6p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_gam6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AGMHE" name="ADP-D-glycero-D-manno-heptose epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AGMHE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.3.20</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : adphep-DD --&gt; adphep-LD</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3619#ABBREVIATION:rfaD#ECNUMBERS:5.1.3.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ADP-L-glycero-D-mannoheptose-6-epimerase#ABBREVIATION:RfaD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3619)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adphep_DD_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adphep_LD_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AGMT" name="agmatinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AGMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.3.11</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : agm + h2o --&gt; ptrc + urea</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2937#ABBREVIATION:speB#ECNUMBERS:3.5.3.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:agmatinase#ABBREVIATION:SpeB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2937)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agm_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ptrc_c" />
                    <speciesReference species="M_urea_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AGPR" name="N-acetyl-g-glutamyl-phosphate reductase">
                <notes>
                    <html:p>Abbreviation: R_AGPR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.38</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : acg5sa + nadp + pi &lt;==&gt; acg5p + h + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3958#ABBREVIATION:argC#ECNUMBERS:1.2.1.38#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglutamate phosphate reductase#ABBREVIATION:ArgC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3958)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acg5sa_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acg5p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AHC" name="adenosylhomocysteinase">
                <notes>
                    <html:p>Abbreviation: R_AHC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.3.1.1</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : ahcys + h2o &lt;==&gt; adn + hcys-L</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_hcys_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AHCYSNS" name="S-adenosylhomocysteine nucleosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AHCYSNS</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 3.2.2.9</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : ahcys + h2o --&gt; ade + rhcys</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0159#ABBREVIATION:pfs#ECNUMBERS:3.2.2.9,-!-,3.2.2.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Methylthioadenosine nucleosidase#ABBREVIATION:Mtn#</html:p>
                    <html:p>GENE ASSOCIATION: (b0159)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_rhcys_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AICART" name="phosphoribosylaminoimidazolecarboxamide formyltransferase">
                <notes>
                    <html:p>Abbreviation: R_AICART</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.1.2.3</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : 10fthf + aicar &lt;==&gt; fprica + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4006#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH#</html:p>
                    <html:p>GENE ASSOCIATION: (b4006)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_10fthf_c" />
                    <speciesReference species="M_aicar_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fprica_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AIRC2" name="phosphoribosylaminoimidazole carboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AIRC2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : air + atp + hco3 --&gt; 5caiz + adp + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reaction according to Neidhardt pg 563 and 569.  According to Meyer et al. Biochemistry 38: 3012-3018pp, this pathway is used in prokaryotes and uses hco3 instead of co2. </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0522#ABBREVIATION:purK#ECNUMBERS:4.1.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosylaminoimidazole carboxylase I#ABBREVIATION:PurK#</html:p>
                    <html:p>GENE ASSOCIATION: (b0522)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_air_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_hco3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5caiz_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AIRC3" name="phosphoribosylaminoimidazole carboxylase (mutase rxn)">
                <notes>
                    <html:p>Abbreviation: R_AIRC3</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : 5aizc &lt;==&gt; 5caiz</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- E.coli uses a two enzymes in the phosphoribosylaminoimidazole carboxylase step to generate 5aizc</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0523#ABBREVIATION:purE#ECNUMBERS:4.1.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosylaminoimidazole carboxylase II#ABBREVIATION:PurE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0523)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5aizc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5caiz_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AKGDH" name="_2-Oxogluterate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AKGDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : akg + coa + nad --&gt; co2 + nadh + succoa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Changed from TEST_AKGDH
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0116#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4#</html:p>
                    <html:p>LOCUS:b0726#ABBREVIATION:sucA#ECNUMBERS:1.2.4.2#</html:p>
                    <html:p>LOCUS:b0727#ABBREVIATION:sucB#ECNUMBERS:2.3.1.61#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA#</html:p>
                    <html:p>NAME:a-ketoglutarate dehydrogenase, A#ABBREVIATION:SucAec#</html:p>
                    <html:p>NAME:a-ketoglutarate, B#ABBREVIATION:SucBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0727) and (b0116) and (b0726)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_succoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AKGt2r" name="_2-oxoglutarate reversible transport via symport">
                <notes>
                    <html:p>Abbreviation: R_AKGt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: akg[e] + h[e] &lt;==&gt; akg[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2587#ABBREVIATION:kgtP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, a-ketoglutarate H symporter#ABBREVIATION:KgtPec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2587)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALAALAr" name="D-alanine-D-alanine ligase (reversible)">
                <notes>
                    <html:p>Abbreviation: R_ALAALAr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.4</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (2) ala-D + atp &lt;==&gt; adp + alaala + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of ALAALA</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0092#ABBREVIATION:ddlB#ECNUMBERS:6.3.2.4#</html:p>
                    <html:p>LOCUS:b0381#ABBREVIATION:ddlA#ECNUMBERS:6.3.2.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-alanine-D-alanine ligase A#ABBREVIATION:DdlA#</html:p>
                    <html:p>NAME:D-alanine-D-alanine ligase B#ABBREVIATION:DdlB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0381) or (b0092)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_D_c" stoichiometry="2" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_alaala_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALAR" name="alanine racemase">
                <notes>
                    <html:p>Abbreviation: R_ALAR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.1.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : ala-L &lt;==&gt; ala-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4053#ABBREVIATION:alr#ECNUMBERS:5.1.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:alanine racemase I#ABBREVIATION:Alrec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4053)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALATA_D2" name="D-alanine transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALATA_D2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ala-D + pydx5p --&gt; pyam5p + pyr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2551#ABBREVIATION:glyA#ECNUMBERS:2.1.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine Hydroxymethyltransferase#ABBREVIATION:GlyA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_D_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyam5p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALATA_L" name="L-alanine transaminase">
                <notes>
                    <html:p>Abbreviation: R_ALATA_L</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.2</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : akg + ala-L &lt;==&gt; glu-L + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_ala_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALATA_L2" name="alanine transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALATA_L2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ala-L + pydx5p --&gt; pyam5p + pyr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2551#ABBREVIATION:glyA#ECNUMBERS:2.1.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine Hydroxymethyltransferase#ABBREVIATION:GlyA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyam5p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALAabc" name="L-alanine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALAabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: ala-L[e] + atp[c] + h2o[c] --&gt; adp[c] + ala-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3454#ABBREVIATION:livF#</html:p>
                    <html:p>LOCUS:b3455#ABBREVIATION:livG#</html:p>
                    <html:p>LOCUS:b3456#ABBREVIATION:livM#</html:p>
                    <html:p>LOCUS:b3457#ABBREVIATION:livH#</html:p>
                    <html:p>LOCUS:b3460#ABBREVIATION:livJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivJ#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivF#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivG#</html:p>
                    <html:p>NAME:ABC, branced chain AA (membrane)#ABBREVIATION:LivH#</html:p>
                    <html:p>NAME:ABC, branced chain AA #ABBREVIATION:LivM#</html:p>
                    <html:p>GENE ASSOCIATION: (b3455) and (b3457) and (b3454) and (b3460) and (b3456)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALAt2r" name="L-alanine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ALAt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: ala-L[e] + h[e] &lt;==&gt; ala-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0007#ABBREVIATION:yaaJ#</html:p>
                    <html:p>LOCUS:b4208#ABBREVIATION:cycA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, D-ala/D-ser/glycine transport#ABBREVIATION:CycAec#</html:p>
                    <html:p>NAME:putative alanine/glycine transporter, AGCS#ABBREVIATION:YaaJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0007) or (b4208)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALCD19" name="alcohol dehydrogenase (glycerol)">
                <notes>
                    <html:p>Abbreviation: R_ALCD19</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.1.1.1</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glyald + h + nadh &lt;==&gt; glyc + nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0356#ABBREVIATION:frmA#ECNUMBERS:1.1.1.1,-!-,1.2.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Putative alcohol dehdrogenase III#ABBREVIATION:AdhC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0356)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyald_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALDD19x" name="aldehyde dehydrogenase (phenylacetaldehyde, NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALDD19x</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.39</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + nad + pacald --&gt; (2) h + nadh + pac</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1385#ABBREVIATION:feaB#ECNUMBERS:1.2.1.39#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phenylacetaldehyde dehydrogenase#ABBREVIATION:FeaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1385)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_pacald_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_pac_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALDD2x" name="aldehyde dehydrogenase (acetaldehyde, NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALDD2x</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.3</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : acald + h2o + nad --&gt; ac + (2) h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Only acetaldehyde considered for now. See also 1.2.1.4. Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. Formerly EC 1.1.1.70</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1300#ABBREVIATION:puuC#ECNUMBERS:1.2.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aldehyde dehdrogenase#ABBREVIATION:AldH#</html:p>
                    <html:p>GENE ASSOCIATION: (b1300)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALLTAH" name="Allantoate amidinohydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALLTAH</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 3.5.3.4</html:p>
                    <html:p>SUBSYSTEM: Nitrogen Metabolism</html:p>
                    <html:p>Equation: [c] : alltt + h2o --&gt; urdglyc + urea</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0516#ABBREVIATION:allC#ECNUMBERS:3.5.3.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:allantoate amidohydrolase#ABBREVIATION:AllC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0516)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alltt_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_urdglyc_c" />
                    <speciesReference species="M_urea_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALLTN" name="allantoinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALLTN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.2.5</html:p>
                    <html:p>SUBSYSTEM: Nitrogen Metabolism</html:p>
                    <html:p>Equation: [c] : alltn + h2o --&gt; alltt + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0512#ABBREVIATION:allB#ECNUMBERS:3.5.2.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:allantoinase#ABBREVIATION:AllB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0512)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alltn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_alltt_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALLTNt2r" name="allantoin transport in via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ALLTNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: alltn[e] + h[e] &lt;==&gt; alltn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0511#ABBREVIATION:ybbW#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative allantoin transporter, NCS1#ABBREVIATION:AllP#</html:p>
                    <html:p>GENE ASSOCIATION: (b0511)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alltn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_alltn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ALTRH" name="altronate hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ALTRH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.7</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : altrn --&gt; 2ddglcn + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3091#ABBREVIATION:uxaA#ECNUMBERS:4.2.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:altronate hydrolase#ABBREVIATION:UxaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3091)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_altrn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddglcn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMALT1" name="Amylomaltase (maltotriose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMALT1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malt + malttr --&gt; glc-D + maltttr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3416#ABBREVIATION:malQ#ECNUMBERS:2.4.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:amylomaltase#ABBREVIATION:MalQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b3416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_c" />
                    <speciesReference species="M_malttr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_maltttr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMALT2" name="Amylomaltase (maltotetraose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMALT2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malt + maltttr --&gt; glc-D + maltpt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3416#ABBREVIATION:malQ#ECNUMBERS:2.4.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:amylomaltase#ABBREVIATION:MalQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b3416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_c" />
                    <speciesReference species="M_maltttr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_maltpt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMALT3" name="Amylomaltase (maltopentaose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMALT3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malt + maltpt --&gt; glc-D + malthx</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3416#ABBREVIATION:malQ#ECNUMBERS:2.4.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:amylomaltase#ABBREVIATION:MalQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b3416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_c" />
                    <speciesReference species="M_maltpt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_malthx_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMALT4" name="Amylomaltase (maltohexaose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMALT4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malt + malthx --&gt; glc-D + malthp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3416#ABBREVIATION:malQ#ECNUMBERS:2.4.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:amylomaltase#ABBREVIATION:MalQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b3416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_c" />
                    <speciesReference species="M_malthx_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_malthp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMANAPE" name="N-acetylmannosamine 6-phosphate epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMANAPE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative</html:p>
                    <html:p>Equation: [c] : acmanap --&gt; acgam6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3223#ABBREVIATION:nanE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetyl-D-mannosamine-6-phosphate epimerase#ABBREVIATION:NanE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3223)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acmanap_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acgam6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMANK" name="N-acetyl-D-mannosamine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMANK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.60</html:p>
                    <html:p>SUBSYSTEM: Putative</html:p>
                    <html:p>Equation: [c] : acmana + atp --&gt; acmanap + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - Kegg R02705</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3222#ABBREVIATION:nanK#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetyl-D-mannosamine kinase#ABBREVIATION:NanK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3222)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acmana_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acmanap_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMAOTr" name="adenosylmethionine-8-amino-7-oxononanoate transaminase">
                <notes>
                    <html:p>Abbreviation: R_AMAOTr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.62</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 8aonn + amet &lt;==&gt; amob + dann</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible version of AMAOT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0774#ABBREVIATION:bioA#ECNUMBERS:2.6.1.62#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenosylmethionine-8-amino-7-oxonanoate aminotransferase#ABBREVIATION:BioAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0774)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_8aonn_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amob_c" />
                    <speciesReference species="M_dann_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMMQT8_2" name="S-adenosylmethione:2-demethylmenaquinone methyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMMQT8_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2dmmq8 + amet --&gt; ahcys + h + mqn8</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added similar reaction to AMMQT8 except that it produces menaquinone not menaquinol</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3929#ABBREVIATION:rraA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:S-adenosylmethionine-2-DMK methyltransferase#ABBREVIATION:MenG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3929)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMPMS" name="_4-amino-2-methyl-5-phosphomethylpyrimidine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMPMS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : air + h2o --&gt; 4ampm + (2) for + (4) h</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR- not sure about byproduct
AMF- reaction unbalanced</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3994#ABBREVIATION:thiC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ThiC protein-4-amino-5-hydroxymethyl-2-methylpyrimidine-P synthesis#ABBREVIATION:ThiC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3994)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_air_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4ampm_c" />
                    <speciesReference species="M_for_c" stoichiometry="2" />
                    <speciesReference species="M_h_c" stoichiometry="4" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AMPN" name="AMP nucleosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AMPN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.2.4</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : amp + h2o --&gt; ade + r5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1982#ABBREVIATION:amn#ECNUMBERS:3.2.2.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:AMP nucleosidase#ABBREVIATION:Amn#</html:p>
                    <html:p>GENE ASSOCIATION: (b1982)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ANPRT" name="anthranilate phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ANPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.18</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : anth + prpp --&gt; ppi + pran</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1263#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anthranilate synthase II#ABBREVIATION:TrpDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1263)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_anth_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_pran_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ANS" name="anthranilate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ANS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.27</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : chor + gln-L --&gt; anth + glu-L + h + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1263#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18#</html:p>
                    <html:p>LOCUS:b1264#ABBREVIATION:trpE#ECNUMBERS:4.1.3.27#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anthranilate synthase II#ABBREVIATION:TrpDec#</html:p>
                    <html:p>NAME:Anthranilate synthase I#ABBREVIATION:TrpEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1264) and (b1263)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chor_c" />
                    <speciesReference species="M_gln_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_anth_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AOXSr" name="_8-amino-7-oxononanoate synthase">
                <notes>
                    <html:p>Abbreviation: R_AOXSr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.47</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ala-L + h + pmcoa &lt;==&gt; 8aonn + co2 + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible version of AOXS</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0776#ABBREVIATION:bioF#ECNUMBERS:2.3.1.47#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_8-amino-7-oxononanoate synthase#ABBREVIATION:BioF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0776)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pmcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_8aonn_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AP4AH" name="Ap4A hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AP4AH</html:p>
                    <html:p>Synonyms: _9</html:p>
                    <html:p>EC Number: 3.6.1.41</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ap4a + h2o --&gt; (2) adp + (2) h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0049#ABBREVIATION:apaH#ECNUMBERS:3.6.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:diadenosine tetraphosphatase#ABBREVIATION:ApaH#</html:p>
                    <html:p>GENE ASSOCIATION: (b0049)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ap4a_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" stoichiometry="2" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AP5AH" name="Ap5A hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AP5AH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ap5a + h2o --&gt; adp + atp + (2) h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0049#ABBREVIATION:apaH#ECNUMBERS:3.6.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:diadenosine tetraphosphatase#ABBREVIATION:ApaH#</html:p>
                    <html:p>GENE ASSOCIATION: (b0049)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ap5a_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_APRAUR" name="_5-amino-6-(5-phosphoribosylamino)uracil reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_APRAUR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.193</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 5apru + h + nadph --&gt; 5aprbu + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0414#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0414)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5apru_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5aprbu_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARAI" name="L-arabinose isomerase">
                <notes>
                    <html:p>Abbreviation: R_ARAI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.4</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : arab-L &lt;==&gt; rbl-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0062#ABBREVIATION:araA#ECNUMBERS:5.3.1.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-arabinose isomerase#ABBREVIATION:AraA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0062)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arab_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_rbl_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARBabc" name="L-arabinose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ARBabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: arab-L[e] + atp[c] + h2o[c] --&gt; adp[c] + arab-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1898#ABBREVIATION:OBSOLETE (AraH_2)#</html:p>
                    <html:p>LOCUS:b1899#ABBREVIATION:OBSOLETE (AraH_1)#</html:p>
                    <html:p>LOCUS:b1900#ABBREVIATION:araG#</html:p>
                    <html:p>LOCUS:b1901#ABBREVIATION:araF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, L-arabinose (periplasm)#ABBREVIATION:AraF#</html:p>
                    <html:p>NAME:ABC, L-arabinose (atp)#ABBREVIATION:AraG#</html:p>
                    <html:p>NAME:ABC, L-arabinose (membrane)#ABBREVIATION:AraH#</html:p>
                    <html:p>GENE ASSOCIATION: (b1900) and (b1898 and b1899) and (b1901)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arab_L_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_arab_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARBt2r" name="L-arabinose transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ARBt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: arab-L[e] + h[e] &lt;==&gt; arab-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2841#ABBREVIATION:araE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, L-arabinose proton symporter#ABBREVIATION:AraE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2841)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arab_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_arab_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARGDC" name="arginine decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ARGDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.19</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : arg-L + h --&gt; agm + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2938#ABBREVIATION:speA#ECNUMBERS:4.1.1.19#</html:p>
                    <html:p>LOCUS:b4117#ABBREVIATION:adiA#ECNUMBERS:4.1.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Arginine decarboxylase#ABBREVIATION:SpeA#</html:p>
                    <html:p>NAME:arginine decarboxylase#ABBREVIATION:AdiA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2938) or (b4117)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arg_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_agm_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARGORNt7" name="arginine/ornithine antiporter">
                <notes>
                    <html:p>Abbreviation: R_ARGORNt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: arg-L[e] + orn[c] &lt;==&gt; arg-L[c] + orn[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1605#ABBREVIATION:ydgI#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative arginine/ornithine antiporter, APC#ABBREVIATION:ArcD#</html:p>
                    <html:p>GENE ASSOCIATION: (b1605)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arg_L_e" />
                    <speciesReference species="M_orn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_arg_L_c" />
                    <speciesReference species="M_orn_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARGSL" name="argininosuccinate lyase">
                <notes>
                    <html:p>Abbreviation: R_ARGSL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.2.1</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : argsuc &lt;==&gt; arg-L + fum</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3960#ABBREVIATION:argH#ECNUMBERS:4.3.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:argininosuccinate lyase#ABBREVIATION:ArgH#</html:p>
                    <html:p>GENE ASSOCIATION: (b3960)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_argsuc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_arg_L_c" />
                    <speciesReference species="M_fum_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARGSS" name="argininosuccinate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ARGSS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.4.5</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : asp-L + atp + citr-L --&gt; amp + argsuc + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3172#ABBREVIATION:argG#ECNUMBERS:6.3.4.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:argininosuccinate synthetase#ABBREVIATION:ArgG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3172)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_citr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_argsuc_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ARGabc" name="L-arginine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ARGabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: arg-L[e] + atp[c] + h2o[c] --&gt; adp[c] + arg-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0860#ABBREVIATION:artJ#</html:p>
                    <html:p>LOCUS:b0861#ABBREVIATION:artM#</html:p>
                    <html:p>LOCUS:b0862#ABBREVIATION:artQ#</html:p>
                    <html:p>LOCUS:b0864#ABBREVIATION:artP#</html:p>
                    <html:p>LOCUS:b2306#ABBREVIATION:hisP#</html:p>
                    <html:p>LOCUS:b2307#ABBREVIATION:hisM#</html:p>
                    <html:p>LOCUS:b2308#ABBREVIATION:hisQ#</html:p>
                    <html:p>LOCUS:b2310#ABBREVIATION:argT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, arginine (periplasm)#ABBREVIATION:ArtJ#</html:p>
                    <html:p>NAME:ABC, arginine (membrane)#ABBREVIATION:ArtQ#</html:p>
                    <html:p>NAME:ABC, arginine (atp&amp;membrane)#ABBREVIATION:ArtP#</html:p>
                    <html:p>NAME:ABC, arginine (membrane)#ABBREVIATION:ArtM#</html:p>
                    <html:p>NAME:ABC, lys/arg/ornithine (periplasm)#ABBREVIATION:ArgT#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/orn (membrane)#ABBREVIATION:HisM#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (atp)#ABBREVIATION:HisP#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (membrane)#ABBREVIATION:HisQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2310) and (b2307) and (b2308) and (b2306) or (b0860) and (b0861) and (b0864) and (b0862)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arg_L_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_arg_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASAD" name="aspartate-semialdehyde dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_ASAD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.11</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : aspsa + nadp + pi &lt;==&gt; 4pasp + h + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3433#ABBREVIATION:asd#ECNUMBERS:1.2.1.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate-semialdehyde dehydrogenase#ABBREVIATION:Asd#</html:p>
                    <html:p>GENE ASSOCIATION: (b3433)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_aspsa_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4pasp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASNN" name="L-asparaginase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASNN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : asn-L + h2o --&gt; asp-L + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0828#ABBREVIATION:iaaA#ECNUMBERS:3.5.1.1#</html:p>
                    <html:p>LOCUS:b1767#ABBREVIATION:ansA#ECNUMBERS:3.5.1.1#</html:p>
                    <html:p>LOCUS:b2957#ABBREVIATION:ansB#ECNUMBERS:3.5.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-asparaginase II#ABBREVIATION:AnsB#</html:p>
                    <html:p>NAME:L-asparaginase I#ABBREVIATION:AnsA#</html:p>
                    <html:p>NAME:putative asparaginase#ABBREVIATION:YbiK#</html:p>
                    <html:p>GENE ASSOCIATION: (b1767) or (b2957) or (b0828)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asn_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASNS1" name="asparagine synthase (glutamine-hydrolysing)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASNS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.5.4</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : asp-L + atp + gln-L + h2o --&gt; amp + asn-L + glu-L + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0674#ABBREVIATION:asnB#ECNUMBERS:6.3.5.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:asparagine synthetase B#ABBREVIATION:AsnB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0674)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_asn_L_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASNS2" name="asparagine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASNS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.1.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : asp-L + atp + nh4 --&gt; amp + asn-L + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3744#ABBREVIATION:asnA#ECNUMBERS:6.3.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:asparagine synthetase A#ABBREVIATION:AsnA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3744)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_asn_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASNabc" name="L-asparagine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASNabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asn-L[e] + atp[c] + h2o[c] --&gt; adp[c] + asn-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asn_L_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_asn_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASNt2r" name="L-asparagine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ASNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asn-L[e] + h[e] &lt;==&gt; asn-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asn_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asn_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASP1DC" name="aspartate 1-decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASP1DC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.11</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + h --&gt; ala-B + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>The E. coli enzyme contains a pyruvoyl group.
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0131#ABBREVIATION:panD#ECNUMBERS:4.1.1.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate 1-decarboxylase#ABBREVIATION:PanD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0131)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_B_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPCT" name="aspartate carbamoyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.1.3.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + cbp --&gt; cbasp + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4244#ABBREVIATION:pyrI#</html:p>
                    <html:p>LOCUS:b4245#ABBREVIATION:pyrB#ECNUMBERS:2.1.3.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate carbamoyltransferase#ABBREVIATION:PyrBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4244 and b4245)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_cbp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cbasp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPK" name="aspartate kinase">
                <notes>
                    <html:p>Abbreviation: R_ASPK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.4</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : asp-L + atp &lt;==&gt; 4pasp + adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0002#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3#</html:p>
                    <html:p>LOCUS:b3940#ABBREVIATION:metL#ECNUMBERS:2.7.2.4,-!-,1.1.1.3#</html:p>
                    <html:p>LOCUS:b4024#ABBREVIATION:lysC#ECNUMBERS:2.7.2.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Homoserine dehydrogenase#ABBREVIATION:MetL#</html:p>
                    <html:p>NAME:Aspartate kinase I#ABBREVIATION:ThrA#</html:p>
                    <html:p>NAME:Aspartokinase III#ABBREVIATION:LysCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0002) or (b4024) or (b3940)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4pasp_c" />
                    <speciesReference species="M_adp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPO3" name="L-aspartate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPO3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + q8 --&gt; iasp + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2574#ABBREVIATION:nadB#ECNUMBERS:1.4.3.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate oxidase#ABBREVIATION:NadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2574)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_iasp_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPO4" name="L-aspartate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPO4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + mqn8 --&gt; iasp + mql8</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2574#ABBREVIATION:nadB#ECNUMBERS:1.4.3.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate oxidase#ABBREVIATION:NadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2574)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_iasp_c" />
                    <speciesReference species="M_mql8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPO5" name="L-aspartate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPO5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + fum --&gt; iasp + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2574#ABBREVIATION:nadB#ECNUMBERS:1.4.3.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate oxidase#ABBREVIATION:NadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2574)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_fum_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_iasp_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPO6" name="L-aspartate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPO6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : asp-L + o2 --&gt; h2o2 + iasp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2574#ABBREVIATION:nadB#ECNUMBERS:1.4.3.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate oxidase#ABBREVIATION:NadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2574)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o2_c" />
                    <speciesReference species="M_iasp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPT" name="L-aspartase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.1.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : asp-L --&gt; fum + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4139#ABBREVIATION:aspA#ECNUMBERS:4.3.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Aspartate ammonia-lyase#ABBREVIATION:AspA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4139)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPTA" name="aspartate transaminase">
                <notes>
                    <html:p>Abbreviation: R_ASPTA</html:p>
                    <html:p>Synonyms: _29</html:p>
                    <html:p>EC Number: 2.6.1.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : akg + asp-L &lt;==&gt; glu-L + oaa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0928#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aspartate aminotransferase#ABBREVIATION:AspC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0928)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_asp_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPabc" name="L-aspartate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asp-L[e] + atp[c] + h2o[c] --&gt; adp[c] + asp-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0652#ABBREVIATION:gltL#</html:p>
                    <html:p>LOCUS:b0653#ABBREVIATION:gltK#</html:p>
                    <html:p>LOCUS:b0654#ABBREVIATION:gltJ#</html:p>
                    <html:p>LOCUS:b0655#ABBREVIATION:gltI#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (periplasm)#ABBREVIATION:GltI#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (membrane)#ABBREVIATION:GltJ#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (membrane)#ABBREVIATION:GltK#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (atp)#ABBREVIATION:GltL#</html:p>
                    <html:p>GENE ASSOCIATION: (b0653) and (b0654) and (b0655) and (b0652)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPt2" name="L-aspartate transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asp-L[e] + h[e] --&gt; asp-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4077#ABBREVIATION:gltP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP#</html:p>
                    <html:p>GENE ASSOCIATION: (b4077)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPt2_2" name="Aspartate transport via proton symport (2 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPt2_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asp-L[e] + (2) h[e] --&gt; asp-L[c] + (2) h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3528#ABBREVIATION:dctA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3528)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_e" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ASPt2_3" name="L-asparate transport via proton symport (3 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ASPt2_3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: asp-L[e] + (3) h[e] --&gt; asp-L[c] + (3) h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4123#ABBREVIATION:dcuB#</html:p>
                    <html:p>LOCUS:b4138#ABBREVIATION:dcuA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Anaerobic C4-dicarboxylate transporter protein#ABBREVIATION:DcuA#</html:p>
                    <html:p>NAME:anaerobic C4-dicarboxylate transporter#ABBREVIATION:DcuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4123) or (b4138)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_e" />
                    <speciesReference species="M_h_e" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                </listOfProducts>
            </reaction>
            <reaction id="R_AST" name="Arginine succinyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_AST</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.109</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : arg-L + succoa --&gt; coa + h + sucarg</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (R00832)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1747#ABBREVIATION:astA#ECNUMBERS:2.3.1.109#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Arginine succinyltransferase#ABBREVIATION:AstA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1747)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arg_L_c" />
                    <speciesReference species="M_succoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_sucarg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ATPM" name="ATP maintenance requirement" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ATPM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : atp + h2o --&gt; adp + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ATPPRT" name="ATP phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ATPPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.17</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + prpp --&gt; ppi + prbatp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2019#ABBREVIATION:hisG#ECNUMBERS:2.4.2.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ATP phosphoribosyltransferase#ABBREVIATION:HisG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2019)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_prbatp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ATPS4r" name="ATP synthase (four protons for one ATP)">
                <notes>
                    <html:p>Abbreviation: R_ATPS4r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.3.14</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: adp[c] + (4) h[e] + pi[c] &lt;==&gt; atp[c] + (3) h[c] + h2o[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of ATPS4 reactioin</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3731#ABBREVIATION:atpC#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3732#ABBREVIATION:atpD#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3733#ABBREVIATION:atpG#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3734#ABBREVIATION:atpA#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3735#ABBREVIATION:atpH#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3736#ABBREVIATION:atpF#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3737#ABBREVIATION:atpE#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3738#ABBREVIATION:atpB#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>LOCUS:b3739#ABBREVIATION:atpI#ECNUMBERS:3.6.3.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ATP synthase F1#ABBREVIATION:AtpF1#</html:p>
                    <html:p>NAME:ATP synthase F0#ABBREVIATION:AtpF0#</html:p>
                    <html:p>NAME:ATP synthase F1-F0-type proton-ATPase#ABBREVIATION:AtpI#</html:p>
                    <html:p>GENE ASSOCIATION: (b3739) and (b3737 and b3736 and b3738) and (b3735 and b3734 and b3733 and b3732 and b3731)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_e" stoichiometry="4" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BETALDHx" name="betaine-aldehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BETALDHx</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 1.2.1.8</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : betald + h2o + nad --&gt; glyb + (2) h + nadh</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0312#ABBREVIATION:betB#ECNUMBERS:1.2.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:betaine aldehyde dehydrogenase#ABBREVIATION:BetB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0312)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_betald_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyb_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BETALDHy" name="betaine-aldehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BETALDHy</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 1.2.1.8</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : betald + h2o + nadp --&gt; glyb + (2) h + nadph</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0312#ABBREVIATION:betB#ECNUMBERS:1.2.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:betaine aldehyde dehydrogenase#ABBREVIATION:BetB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0312)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_betald_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyb_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BPNT" name="_3',5'-bisphosphate nucleotidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BPNT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.7</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + pap --&gt; amp + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pap_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BSORx" name="Biotin sulfoxide reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BSORx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : btnso + h + nadh --&gt; btn + h2o + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3551#ABBREVIATION:bisC#ECNUMBERS:1.-.-.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:biotin sulfoxide reductase#ABBREVIATION:BisC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_btnso_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_btn_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BSORy" name="Biotin sulfoxide reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BSORy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : btnso + h + nadph --&gt; btn + h2o + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3551#ABBREVIATION:bisC#ECNUMBERS:1.-.-.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:biotin sulfoxide reductase#ABBREVIATION:BisC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_btnso_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_btn_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BTS2" name="biotin synthase (ala-L producing)">
                <notes>
                    <html:p>Abbreviation: R_BTS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : cys-L + dtbt &lt;==&gt; ala-L + btn + (2) h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- based on article (Biochemistry 2002, 41, 9145-9152)
AMf- reaction charge inbalanced</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0775#ABBREVIATION:bioB#ECNUMBERS:2.8.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Biotin synthase#ABBREVIATION:BioBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0775)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_dtbt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_btn_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BUTCT" name="Acetyl-CoA:butyrate-CoA transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BUTCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.8.3.8</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + but --&gt; ac + btcoa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (R01179)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2221#ABBREVIATION:atoD#ECNUMBERS:2.8.3.8#</html:p>
                    <html:p>LOCUS:b2222#ABBREVIATION:atoA#ECNUMBERS:2.8.3.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetyl-CoA: acetoacetyl -CoA transferase#ABBREVIATION:AtoADec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2222 and b2221)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_but_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_btcoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BUTt2r" name="Butyrate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_BUTt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: but[e] + h[e] &lt;==&gt; but[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2223#ABBREVIATION:atoE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative short chain fatty acid transporter#ABBREVIATION:AtoE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2223)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_but_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_but_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_BiomassEcoli" name="BiomassEcoli" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_BiomassEcoli</html:p>
                    <html:p>Equation: [c] : (0.05) 5mthf + (0.00005) accoa + (0.488) ala-L + (0.001) amp + (0.281) arg-L + (0.229) asn-L + (0.229) asp-L + (45.7318) atp + (0.000129) clpn_EC + (0.000006) coa + (0.126) ctp + (0.087) cys-L + (0.0247) datp + (0.0254) dctp + (0.0254) dgtp + (0.0247) dttp + (0.00001) fad + (0.25) gln-L + (0.25) glu-L + (0.582) gly + (0.154) glycogen + (0.203) gtp + (45.5608) h2o + (0.09) his-L + (0.276) ile-L + (0.428) leu-L + (0.0084) lps_EC + (0.326) lys-L + (0.146) met-L + (0.00215) nad + (0.00005) nadh + (0.00013) nadp + (0.0004) nadph + (0.001935) pe_EC + (0.0276) peptido_EC + (0.000464) pg_EC + (0.176) phe-L + (0.21) pro-L + (0.000052) ps_EC + (0.035) ptrc + (0.205) ser-L + (0.007) spmd + (0.000003) succoa + (0.241) thr-L + (0.054) trp-L + (0.131) tyr-L + (0.003) udpg + (0.136) utp + (0.402) val-L --&gt; (45.5608) adp + (45.56035) h + (45.5628) pi + (0.7302) ppi</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mthf_c" stoichiometry="0.05" />
                    <speciesReference species="M_accoa_c" stoichiometry="5e-005" />
                    <speciesReference species="M_ala_L_c" stoichiometry="0.488" />
                    <speciesReference species="M_amp_c" stoichiometry="0.001" />
                    <speciesReference species="M_arg_L_c" stoichiometry="0.281" />
                    <speciesReference species="M_asn_L_c" stoichiometry="0.229" />
                    <speciesReference species="M_asp_L_c" stoichiometry="0.229" />
                    <speciesReference species="M_atp_c" stoichiometry="45.7318" />
                    <speciesReference species="M_clpn_EC_c" stoichiometry="0.000129" />
                    <speciesReference species="M_coa_c" stoichiometry="6e-006" />
                    <speciesReference species="M_ctp_c" stoichiometry="0.126" />
                    <speciesReference species="M_cys_L_c" stoichiometry="0.087" />
                    <speciesReference species="M_datp_c" stoichiometry="0.0247" />
                    <speciesReference species="M_dctp_c" stoichiometry="0.0254" />
                    <speciesReference species="M_dgtp_c" stoichiometry="0.0254" />
                    <speciesReference species="M_dttp_c" stoichiometry="0.0247" />
                    <speciesReference species="M_fad_c" stoichiometry="1e-005" />
                    <speciesReference species="M_gln_L_c" stoichiometry="0.25" />
                    <speciesReference species="M_glu_L_c" stoichiometry="0.25" />
                    <speciesReference species="M_gly_c" stoichiometry="0.582" />
                    <speciesReference species="M_glycogen_c" stoichiometry="0.154" />
                    <speciesReference species="M_gtp_c" stoichiometry="0.203" />
                    <speciesReference species="M_h2o_c" stoichiometry="45.5608" />
                    <speciesReference species="M_his_L_c" stoichiometry="0.09" />
                    <speciesReference species="M_ile_L_c" stoichiometry="0.276" />
                    <speciesReference species="M_leu_L_c" stoichiometry="0.428" />
                    <speciesReference species="M_lps_EC_c" stoichiometry="0.0084" />
                    <speciesReference species="M_lys_L_c" stoichiometry="0.326" />
                    <speciesReference species="M_met_L_c" stoichiometry="0.146" />
                    <speciesReference species="M_nad_c" stoichiometry="0.00215" />
                    <speciesReference species="M_nadh_c" stoichiometry="5e-005" />
                    <speciesReference species="M_nadp_c" stoichiometry="0.00013" />
                    <speciesReference species="M_nadph_c" stoichiometry="0.0004" />
                    <speciesReference species="M_pe_EC_c" stoichiometry="0.001935" />
                    <speciesReference species="M_peptido_EC_c" stoichiometry="0.0276" />
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.000464" />
                    <speciesReference species="M_phe_L_c" stoichiometry="0.176" />
                    <speciesReference species="M_pro_L_c" stoichiometry="0.21" />
                    <speciesReference species="M_ps_EC_c" stoichiometry="5.2e-005" />
                    <speciesReference species="M_ptrc_c" stoichiometry="0.035" />
                    <speciesReference species="M_ser_L_c" stoichiometry="0.205" />
                    <speciesReference species="M_spmd_c" stoichiometry="0.007" />
                    <speciesReference species="M_succoa_c" stoichiometry="3e-006" />
                    <speciesReference species="M_thr_L_c" stoichiometry="0.241" />
                    <speciesReference species="M_trp_L_c" stoichiometry="0.054" />
                    <speciesReference species="M_tyr_L_c" stoichiometry="0.131" />
                    <speciesReference species="M_udpg_c" stoichiometry="0.003" />
                    <speciesReference species="M_utp_c" stoichiometry="0.136" />
                    <speciesReference species="M_val_L_c" stoichiometry="0.402" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" stoichiometry="45.5608" />
                    <speciesReference species="M_h_c" stoichiometry="45.56035" />
                    <speciesReference species="M_pi_c" stoichiometry="45.5628" />
                    <speciesReference species="M_ppi_c" stoichiometry="0.7302" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C120SN" name="Fatty acid biosynthesis (n-C12:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C120SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (14) h + (4) malACP + (10) nadph --&gt; (4) ACP + (4) co2 + ddcaACP + (5) h2o + (10) nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>TV, JR
Neidhard pg. 615</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0180) and (b1095) and (b1288) and (b1093) or (b2323) and (b0180) and (b1093) and (b1288) or (b2323) and (b0954) and (b1093) and (b1288) or (b0954) and (b1095) and (b1093) and (b1288)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="14" />
                    <speciesReference species="M_malACP_c" stoichiometry="4" />
                    <speciesReference species="M_nadph_c" stoichiometry="10" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="4" />
                    <speciesReference species="M_co2_c" stoichiometry="4" />
                    <speciesReference species="M_ddcaACP_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="5" />
                    <speciesReference species="M_nadp_c" stoichiometry="10" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C140SN" name="Fatty acid biosynthesis (n-C14:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C140SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (17) h + (5) malACP + (12) nadph --&gt; (5) ACP + (5) co2 + (6) h2o + myrsACP + (12) nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
Neidhardt</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0180) and (b2323) and (b1093) and (b1288) or (b2323) and (b0954) and (b1093) and (b1288) or (b0954) and (b1095) and (b1093) and (b1288) or (b0180) and (b1095) and (b1288) and (b1093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="17" />
                    <speciesReference species="M_malACP_c" stoichiometry="5" />
                    <speciesReference species="M_nadph_c" stoichiometry="12" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="5" />
                    <speciesReference species="M_co2_c" stoichiometry="5" />
                    <speciesReference species="M_h2o_c" stoichiometry="6" />
                    <speciesReference species="M_myrsACP_c" />
                    <speciesReference species="M_nadp_c" stoichiometry="12" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C141SN" name="Fatty acid biosynthesis (n-C14:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C141SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (16) h + (5) malACP + (11) nadph --&gt; (5) ACP + (5) co2 + (6) h2o + (11) nadp + tdeACP</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2323) and (b0180) and (b0954) and (b1288) and (b1093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="16" />
                    <speciesReference species="M_malACP_c" stoichiometry="5" />
                    <speciesReference species="M_nadph_c" stoichiometry="11" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="5" />
                    <speciesReference species="M_co2_c" stoichiometry="5" />
                    <speciesReference species="M_h2o_c" stoichiometry="6" />
                    <speciesReference species="M_nadp_c" stoichiometry="11" />
                    <speciesReference species="M_tdeACP_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C160SN" name="Fatty acid biosynthesis (n-C16:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C160SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (20) h + (6) malACP + (14) nadph --&gt; (6) ACP + (6) co2 + (7) h2o + (14) nadp + palmACP</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0180) and (b1095) and (b1288) and (b1093) or (b2323) and (b0180) and (b1288) and (b1093) or (b2323) and (b0954) and (b1288) and (b1093) or (b0954) and (b1095) and (b1288) and (b1093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="20" />
                    <speciesReference species="M_malACP_c" stoichiometry="6" />
                    <speciesReference species="M_nadph_c" stoichiometry="14" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="6" />
                    <speciesReference species="M_co2_c" stoichiometry="6" />
                    <speciesReference species="M_h2o_c" stoichiometry="7" />
                    <speciesReference species="M_nadp_c" stoichiometry="14" />
                    <speciesReference species="M_palmACP_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C161SN" name="Fatty acid biosynthesis (n-C16:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C161SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (19) h + (6) malACP + (13) nadph --&gt; (6) ACP + (6) co2 + (7) h2o + hdeACP + (13) nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2323) and (b0180) and (b0954) and (b1093) and (b1288)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="19" />
                    <speciesReference species="M_malACP_c" stoichiometry="6" />
                    <speciesReference species="M_nadph_c" stoichiometry="13" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="6" />
                    <speciesReference species="M_co2_c" stoichiometry="6" />
                    <speciesReference species="M_h2o_c" stoichiometry="7" />
                    <speciesReference species="M_hdeACP_c" />
                    <speciesReference species="M_nadp_c" stoichiometry="13" />
                </listOfProducts>
            </reaction>
            <reaction id="R_C181SN" name="Fatty acid biosynthesis (n-C18:1)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_C181SN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : actACP + (22) h + (7) malACP + (15) nadph --&gt; (7) ACP + (7) co2 + (8) h2o + (15) nadp + octeACP</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0180#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>LOCUS:b0954#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60#</html:p>
                    <html:p>LOCUS:b1288#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9#</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ#</html:p>
                    <html:p>NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2323) and (b0180) and (b0954) and (b1095) and (b1093) and (b1288)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="22" />
                    <speciesReference species="M_malACP_c" stoichiometry="7" />
                    <speciesReference species="M_nadph_c" stoichiometry="15" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="7" />
                    <speciesReference species="M_co2_c" stoichiometry="7" />
                    <speciesReference species="M_h2o_c" stoichiometry="8" />
                    <speciesReference species="M_nadp_c" stoichiometry="15" />
                    <speciesReference species="M_octeACP_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CADVt" name="Lysine/Cadaverine antiporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CADVt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: _15dap[c] + h[e] + lys-L[e] --&gt; 15dap[e] + h[c] + lys-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Depletion of proton gradient is not for sure</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4132#ABBREVIATION:cadB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, lysine cadaverine antiporter#ABBREVIATION:CadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4132)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_15dap_c" />
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_lys_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_15dap_e" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lys_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CAT" name="catalase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CAT</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 1.11.1.6</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : (2) h2o2 --&gt; (2) h2o + o2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1732#ABBREVIATION:katE#ECNUMBERS:1.11.1.6#</html:p>
                    <html:p>LOCUS:b3942#ABBREVIATION:katG#ECNUMBERS:1.11.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:catalase#ABBREVIATION:KatE#</html:p>
                    <html:p>NAME:catalase#ABBREVIATION:KatG#</html:p>
                    <html:p>GENE ASSOCIATION: (b1732) or (b3942)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o2_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_o2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CBIAT_DELETE" name="Cobinamide adenyltransferase">
                <notes>
                    <html:p>Abbreviation: R_CBIAT_DELETE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + cbi + h2o &lt;==&gt; adocbi + pi + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (EC 2.5.1--)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1270#ABBREVIATION:btuR#ECNUMBERS:2.5.1.-,-!-,2.5.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cob(1)alamin and cobinamide adenosyltransferase#ABBREVIATION:BtuR#</html:p>
                    <html:p>GENE ASSOCIATION: (b1270)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cbi_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adocbi_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CBL1abc" name="Cob(1)alamin transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CBL1abc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + cbl1[e] + h2o[c] --&gt; adp[c] + cbl1[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0158#ABBREVIATION:btuF#</html:p>
                    <html:p>LOCUS:b1709#ABBREVIATION:btuD#ECNUMBERS:3.6.3.33#</html:p>
                    <html:p>LOCUS:b1711#ABBREVIATION:btuC#</html:p>
                    <html:p>LOCUS:b3966#ABBREVIATION:btuB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:outer porin transporter for B12/cobalamin#ABBREVIATION:BtuB#</html:p>
                    <html:p>NAME:ABC vitamin B12 transporter (membrane)#ABBREVIATION:BtuC#</html:p>
                    <html:p>NAME:ABC vitamin B12 transporter (atp_bind)#ABBREVIATION:BtuD#</html:p>
                    <html:p>NAME:ABC vitamin B12 transporter (peri_bind)#ABBREVIATION:BtuF#</html:p>
                    <html:p>GENE ASSOCIATION: (b1709) and (b0158) and (b3966) and (b1711)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cbl1_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_cbl1_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CBLAT_DELETE" name="cob(I)alamin adenosyltransferase">
                <notes>
                    <html:p>Abbreviation: R_CBLAT_DELETE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.17</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + cbl1 + h2o &lt;==&gt; adocbl + pi + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1270#ABBREVIATION:btuR#ECNUMBERS:2.5.1.-,-!-,2.5.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cob(1)alamin and cobinamide adenosyltransferase#ABBREVIATION:BtuR#</html:p>
                    <html:p>GENE ASSOCIATION: (b1270)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cbl1_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adocbl_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CBMK" name="Carbamate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CBMK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.2</html:p>
                    <html:p>SUBSYSTEM: Putative</html:p>
                    <html:p>Equation: [c] : atp + co2 + nh4 --&gt; adp + cbp + (2) h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0521#ABBREVIATION:ybcF#</html:p>
                    <html:p>LOCUS:b0323#ABBREVIATION:yahI#</html:p>
                    <html:p>LOCUS:b2874#ABBREVIATION:yqeA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative carbamate kinase#ABBREVIATION:YahI#</html:p>
                    <html:p>NAME:putative carbamate kinase#ABBREVIATION:YqeA#</html:p>
                    <html:p>NAME:putative carbamate kinase#ABBREVIATION:ArcCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0521) or (b0323) or (b2874)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_cbp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CBPS" name="carbamoyl-phosphate synthase (glutamine-hydrolysing)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CBPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.5.5</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : (2) atp + gln-L + h2o + hco3 --&gt; (2) adp + cbp + glu-L + (2) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0032#ABBREVIATION:carA#ECNUMBERS:6.3.5.5#</html:p>
                    <html:p>LOCUS:b0033#ABBREVIATION:carB#ECNUMBERS:6.3.5.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:carbamoyl-phosphate synthetase#ABBREVIATION:Car#</html:p>
                    <html:p>GENE ASSOCIATION: (b0032 and b0033)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" stoichiometry="2" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_hco3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" stoichiometry="2" />
                    <speciesReference species="M_cbp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CDAPPA_EC" name="CDP-Diacylglycerol pyrophostatase (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CDAPPA_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.26</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : (0.02) cdpdag_EC + h2o --&gt; cmp + (2) h + (0.02) pa_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3918#ABBREVIATION:cdh#ECNUMBERS:3.6.1.26#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:CDP-diacyglycerol pyrophosphatase#ABBREVIATION:Cdhec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3918)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pa_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CDPMEK" name="_4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CDPMEK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4c2me + atp --&gt; 2p4c2me + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC 2.7.1.148</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1208#ABBREVIATION:ispE#ECNUMBERS:2.7.1.148#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_4-diphosphocytidyl-2C-methyl-erythritol kinase#ABBREVIATION:IspE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1208)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4c2me_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2p4c2me_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CHLabc" name="choline transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CHLabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: atp[c] + chol[e] + h2o[c] --&gt; adp[c] + chol[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2128#ABBREVIATION:yehW#</html:p>
                    <html:p>LOCUS:b2129#ABBREVIATION:yehX#</html:p>
                    <html:p>LOCUS:b2130#ABBREVIATION:yehY#</html:p>
                    <html:p>LOCUS:b2131#ABBREVIATION:yehZ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (membrane)#ABBREVIATION:YehW#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (atp_bind)#ABBREVIATION:YehX#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (membrane)#ABBREVIATION:YehY#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (peri_bind)#ABBREVIATION:YehZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2128) and (b2130) and (b2131) and (b2129)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_chol_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_chol_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CHLt2r" name="choline transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_CHLt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: chol[e] + h[e] &lt;==&gt; chol[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0314#ABBREVIATION:betT#</html:p>
                    <html:p>LOCUS:b1801#ABBREVIATION:yeaV#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:BCCT, choline transporter#ABBREVIATION:BetT#</html:p>
                    <html:p>NAME:putative betaine/choline/glycine transporter, BCCT#ABBREVIATION:YeaV#</html:p>
                    <html:p>GENE ASSOCIATION: (b0314) or (b1801)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chol_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_chol_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CHORM" name="chorismate mutase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CHORM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.99.5</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : chor --&gt; pphn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2599#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51#</html:p>
                    <html:p>LOCUS:b2600#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Chorismate mutase P#ABBREVIATION:PheA#</html:p>
                    <html:p>NAME:Chorismate mutase T#ABBREVIATION:TyrAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2600) or (b2599)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chor_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pphn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CHORS" name="chorismate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CHORS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.3.5</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 3psme --&gt; chor + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previously EC 4.6.1.4. Now EC 4.2.3.5</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2329#ABBREVIATION:aroC#ECNUMBERS:4.2.3.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Chorismate synthase#ABBREVIATION:AroC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2329)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3psme_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_chor_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CHRPL" name="Chorismate pyruvate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CHRPL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : chor --&gt; 4hbz + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR (EC 4.1.3.-)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4039#ABBREVIATION:ubiC#ECNUMBERS:4.1.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:chorismate pyruvate lyase#ABBREVIATION:UbiC#</html:p>
                    <html:p>GENE ASSOCIATION: (b4039)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chor_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4hbz_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CINNDO" name="Cinnamate dioxygenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CINNDO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : cinnm + h + nadh + o2 --&gt; cenchddd + nad</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR- see PMID 9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2538#ABBREVIATION:hcaE#ECNUMBERS:1.14.1.-#</html:p>
                    <html:p>LOCUS:b2539#ABBREVIATION:hcaF#ECNUMBERS:1.14.1.-#</html:p>
                    <html:p>LOCUS:b2540#ABBREVIATION:hcaC#</html:p>
                    <html:p>LOCUS:b2542#ABBREVIATION:hcaD#ECNUMBERS:1.18.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-phenylpropionate dioxygenase#ABBREVIATION:HcaCDEF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2542 and b2539 and b2538 and b2540)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cinnm_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cenchddd_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CITL" name="Citrate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CITL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.6</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : cit --&gt; ac + oaa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0615#ABBREVIATION:citF#ECNUMBERS:4.1.3.6,-!-,2.8.3.10#</html:p>
                    <html:p>LOCUS:b0616#ABBREVIATION:citE#ECNUMBERS:4.1.3.6,-!-,4.1.3.34#</html:p>
                    <html:p>LOCUS:b0617#ABBREVIATION:citD#ECNUMBERS:4.1.3.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Citrate lyase#ABBREVIATION:CitDEF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0616 and b0615 and b0617)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cit_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CITt7" name="Citrate transport via succinate antiport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CITt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: cit[e] + succ[c] --&gt; cit[c] + succ[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0612#ABBREVIATION:citT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DASS citrate:succinate antiporter#ABBREVIATION:CitT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0612)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cit_e" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cit_c" />
                    <speciesReference species="M_succ_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CLPNS_EC" name="Cardiolipin Synthase (E.coli)">
                <notes>
                    <html:p>Abbreviation: R_CLPNS_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : (0.04) pg_EC &lt;==&gt; (0.02) clpn_EC + glyc</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reaction and metabolites are based on fatty acid composition of E. coli (EC 2.7.8.-)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1249#ABBREVIATION:cls#ECNUMBERS:2.7.8.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cardiolipin synthase#ABBREVIATION:Cls#</html:p>
                    <html:p>GENE ASSOCIATION: (b1249)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.04" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_clpn_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_glyc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CMPN" name="CMP nucleosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CMPN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.2.10</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : cmp + h2o --&gt; csn + r5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - also acts on dUMP, dCMP,dTMP, and presumably TMP and UMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_csn_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CO2t" name="CO2 transporter via diffusion">
                <notes>
                    <html:p>Abbreviation: R_CO2t</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: co2[e] &lt;==&gt; co2[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
renamed from CO2TPr to CO2t
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_co2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CPPPGO" name="coproporphyrinogen oxidase (O2 required)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CPPPGO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.3.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : cpppg3 + (2) h + o2 --&gt; (2) co2 + (2) h2o + pppg9</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2436#ABBREVIATION:hemF#ECNUMBERS:1.3.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:coproporphyrinogen III oxidase#ABBREVIATION:HemF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2436)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cpppg3_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_pppg9_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CRNBTCT" name="gamma-butyrobetainyl-CoA: carnitine CoA transferase">
                <notes>
                    <html:p>Abbreviation: R_CRNBTCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : bbtcoa + crn &lt;==&gt; crncoa + gbbtn</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0038#ABBREVIATION:caiB#ECNUMBERS:2.8.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:gamma-butyrobetainyl-CoA: L-carnitine CoA transferase#ABBREVIATION:CaiB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0038)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_bbtcoa_c" />
                    <speciesReference species="M_crn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_crncoa_c" />
                    <speciesReference species="M_gbbtn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CRNCBCT" name="crotonobetainyl-CoA: carnitine CoA transferase">
                <notes>
                    <html:p>Abbreviation: R_CRNCBCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : crn + ctbtcoa &lt;==&gt; crncoa + ctbt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0038#ABBREVIATION:caiB#ECNUMBERS:2.8.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:gamma-butyrobetainyl-CoA: L-carnitine CoA transferase#ABBREVIATION:CaiB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0038)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_crn_c" />
                    <speciesReference species="M_ctbtcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_crncoa_c" />
                    <speciesReference species="M_ctbt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CRNCDH" name="Carnityl-CoA dehydratse">
                <notes>
                    <html:p>Abbreviation: R_CRNCDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : crncoa &lt;==&gt; ctbtcoa + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0036#ABBREVIATION:caiD#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:carnitine-CoA dehydratase#ABBREVIATION:CaiD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0036)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_crncoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ctbtcoa_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CRNt7" name="Carnitine/butyrobetaine antiporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CRNt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: crn[e] + gbbtn[c] --&gt; crn[c] + gbbtn[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0040#ABBREVIATION:caiT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:BCCT, carnitine/butyrobetaine antiporter#ABBREVIATION:CaiT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0040)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_crn_e" />
                    <speciesReference species="M_gbbtn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_crn_c" />
                    <speciesReference species="M_gbbtn_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CS" name="citrate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : accoa + h2o + oaa --&gt; cit + coa + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>old EC number (4.1.3.7) is obsolete -- transferred to 2.3.3.1
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0720#ABBREVIATION:gltA#ECNUMBERS:2.3.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:citrate synthase#ABBREVIATION:GltA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0720)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cit_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CSND" name="Cytosine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CSND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : csn + h + h2o --&gt; nh4 + ura</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0337#ABBREVIATION:codA#ECNUMBERS:3.5.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytosine deaminase#ABBREVIATION:CodA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0337)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_csn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_ura_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CSNt2" name="cytosine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CSNt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: csn[e] + h[e] --&gt; csn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0336#ABBREVIATION:codB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytosine H symporter#ABBREVIATION:CodB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0336)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_csn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_csn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CTPS2" name="CTP synthase (glutamine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CTPS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.4.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + gln-L + h2o + utp --&gt; adp + ctp + glu-L + (2) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2780#ABBREVIATION:pyrG#ECNUMBERS:6.3.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:CTP synthetase#ABBREVIATION:PyrG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2780)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_utp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYANST" name="Cyanide sulfurtransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYANST</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 2.8.1.1</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : cyan + tsul --&gt; h + so3 + tcynt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3425#ABBREVIATION:glpE#ECNUMBERS:2.8.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thiosulfate/cyanide sulfurtransferase#ABBREVIATION:GlpE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3425)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cyan_c" />
                    <speciesReference species="M_tsul_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_so3_c" />
                    <speciesReference species="M_tcynt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYNTAH" name="Cyanate aminohydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYNTAH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nitrogen Metabolism</html:p>
                    <html:p>Equation: [c] : cynt + (3) h + hco3 --&gt; (2) co2 + nh4</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0340#ABBREVIATION:cynS#ECNUMBERS:4.2.1.104#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cyanate aminohydrolase#ABBREVIATION:CynS#</html:p>
                    <html:p>GENE ASSOCIATION: (b0340)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cynt_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_hco3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" stoichiometry="2" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYNTt2" name="Cyanate transport via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYNTt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: cynt[e] + h[e] --&gt; cynt[c] + h[c]</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0341#ABBREVIATION:cynX#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, putative cyanate transport#ABBREVIATION:CynX#</html:p>
                    <html:p>GENE ASSOCIATION: (b0341)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cynt_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cynt_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYSDS" name="Cysteine Desulfhydrase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYSDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.99.1</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : cys-L + h2o --&gt; h2s + nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- also acts on L-tryptophan and L-serine
EC 4.4.1.1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3708#ABBREVIATION:tnaA#ECNUMBERS:4.1.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tryptophan deaminase#ABBREVIATION:TnaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3708)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2s_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYSS" name="cysteine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYSS</html:p>
                    <html:p>Synonyms: _8</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : acser + h2s --&gt; ac + cys-L + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC changed to 2.5.1.47 from 4.2.99.8</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2414#ABBREVIATION:cysK#ECNUMBERS:2.5.1.47#</html:p>
                    <html:p>LOCUS:b2421#ABBREVIATION:cysM#ECNUMBERS:2.5.1.47#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Cysteine synthase A#ABBREVIATION:CysKec#</html:p>
                    <html:p>NAME:Cysteine Synthase B#ABBREVIATION:CysM#</html:p>
                    <html:p>GENE ASSOCIATION: (b2414) or (b2421)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acser_c" />
                    <speciesReference species="M_h2s_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYSTL" name="cystathionine b-lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYSTL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.4.1.8</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : cyst-L + h2o --&gt; hcys-L + nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1622#ABBREVIATION:malY#ECNUMBERS:4.4.1.8#</html:p>
                    <html:p>LOCUS:b3008#ABBREVIATION:metC#ECNUMBERS:4.4.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cystathionine beta-lyase#ABBREVIATION:MetC#</html:p>
                    <html:p>NAME:beta-cystathionase#ABBREVIATION:MalY#</html:p>
                    <html:p>GENE ASSOCIATION: (b3008) or (b1622)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cyst_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hcys_L_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYSabc" name="L-cysteine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYSabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + cys-L[e] + h2o[c] --&gt; adp[c] + cys-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cys_L_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTBD" name="cytochrome oxidase bd (ubiquinol-8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYTBD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[c] + (0.5) o2[c] + q8h2[c] --&gt; (2) h[e] + h2o[c] + q8[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR
EC 1.10.2.2 and 1.9.3.1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0733#ABBREVIATION:cydA#ECNUMBERS:1.9.3.-#</html:p>
                    <html:p>LOCUS:b0734#ABBREVIATION:cydB#ECNUMBERS:1.9.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytochrome oxidase bd#ABBREVIATION:CydA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0733 and b0734)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_o2_c" stoichiometry="0.5" />
                    <speciesReference species="M_q8h2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_q8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTBO3" name="cytochrome oxidase bo3 (ubiquinol-8: 2.5 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYTBO3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2.5) h[c] + (0.5) o2[c] + q8h2[c] --&gt; (2.5) h[e] + h2o[c] + q8[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR
EC 1.10.2.2 and 1.9.3.1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0429#ABBREVIATION:cyoD#ECNUMBERS:1.10.3.-#</html:p>
                    <html:p>LOCUS:b0430#ABBREVIATION:cyoC#ECNUMBERS:1.10.3.-#</html:p>
                    <html:p>LOCUS:b0431#ABBREVIATION:cyoB#ECNUMBERS:1.10.3.-#</html:p>
                    <html:p>LOCUS:b0432#ABBREVIATION:cyoA#ECNUMBERS:1.10.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytochrome oxidase bo3#ABBREVIATION:CyoA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0432 and b0431 and b0429 and b0430)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2.5" />
                    <speciesReference species="M_o2_c" stoichiometry="0.5" />
                    <speciesReference species="M_q8h2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2.5" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_q8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTD" name="cytidine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYTD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : cytd + h + h2o --&gt; nh4 + uri</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2143#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2143)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cytd_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_uri_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTDK2" name="cytidine kinase (GTP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_CYTDK2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : cytd + gtp --&gt; cmp + gdp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2066#ABBREVIATION:udk#ECNUMBERS:2.7.1.48#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uridine/cytidine kinase#ABBREVIATION:Udk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2066)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cytd_c" />
                    <speciesReference species="M_gtp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>

            <reaction id="R_CYTDt2r" name="cytidine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_CYTDt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: cytd[e] + h[e] &lt;==&gt; cytd[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cytd_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cytd_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTK1" name="cytidylate kinase (CMP)">
                <notes>
                    <html:p>Abbreviation: R_CYTK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.14</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + cmp &lt;==&gt; adp + cdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0910#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0910)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_cdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_CYTK2" name="cytidylate kinase (dCMP)">
                <notes>
                    <html:p>Abbreviation: R_CYTK2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.14</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dcmp &lt;==&gt; adp + dcdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0910#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0910)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dcmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dcdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DAAD" name="D-Amino acid dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DAAD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.99.1</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : ala-D + fad + h2o --&gt; fadh2 + nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1189#ABBREVIATION:dadA#ECNUMBERS:1.4.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-amino acid dehydrogenase#ABBREVIATION:DadA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1189)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_D_c" />
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fadh2_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DADA" name="Deoxyadenosine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DADA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dad-2 + h + h2o --&gt; din + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1623#ABBREVIATION:add#ECNUMBERS:3.5.4.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:adenosine deaminase#ABBREVIATION:Add#</html:p>
                    <html:p>GENE ASSOCIATION: (b1623)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dad_2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_din_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DADK" name="deoxyadenylate kinase">
                <notes>
                    <html:p>Abbreviation: R_DADK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.11</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + damp &lt;==&gt; adp + dadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>AMP can also act as acceptor</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0474#ABBREVIATION:adk#ECNUMBERS:2.7.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Adenylate kinase#ABBREVIATION:Adk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0474)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_damp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DADNt2" name="deoxyadenosine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DADNt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: dad-2[e] + h[e] --&gt; dad-2[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2393#ABBREVIATION:nupC#</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>NAME:NUP, nucleoside H symporter#ABBREVIATION:NupCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964) or (b2393)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dad_2_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dad_2_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DAGK_EC" name="Diacylglycerol kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DAGK_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.107</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) 12dgr_EC + atp --&gt; adp + h + (0.02) pa_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4042#ABBREVIATION:dgkA#ECNUMBERS:2.7.1.107#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Diacylglycerol kinase#ABBREVIATION:DgkA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4042)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_12dgr_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pa_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DALAt2r" name="D-alanine transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_DALAt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: ala-D[e] + h[e] &lt;==&gt; ala-D[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4208#ABBREVIATION:cycA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, D-ala/D-ser/glycine transport#ABBREVIATION:CycAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4208)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_D_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_D_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DAPDC" name="diaminopimelate decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DAPDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.20</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : 26dap-M + h --&gt; co2 + lys-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2838#ABBREVIATION:lysA#ECNUMBERS:4.1.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Diaminopimelate decarboxylase#ABBREVIATION:LysA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2838)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_26dap_M_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_lys_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DAPE" name="diaminopimelate epimerase">
                <notes>
                    <html:p>Abbreviation: R_DAPE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.1.7</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : 26dap-LL &lt;==&gt; 26dap-M</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3809#ABBREVIATION:dapF#ECNUMBERS:5.1.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Diaminopimelate epimerase#ABBREVIATION:DapF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3809)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_26dap_LL_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_26dap_M_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DAPabc" name="M-diaminopimelic acid ABC transport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DAPabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: _26dap-M[e] + atp[c] + h2o[c] --&gt; 26dap-M[c] + adp[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_26dap_M_e" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_26dap_M_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DASYN_EC" name="CDP-Diacylglycerol synthetase (Ecoli)">
                <notes>
                    <html:p>Abbreviation: R_DASYN_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.41</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : ctp + h + (0.02) pa_EC &lt;==&gt; (0.02) cdpdag_EC + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0175#ABBREVIATION:cdsA#ECNUMBERS:2.7.7.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:CDP-diglyceride synthetase#ABBREVIATION:CdsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0175)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pa_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DB4PS" name="_3,4-Dihydroxy-2-butanone-4-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DB4PS</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ru5p-D --&gt; db4p + for + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>No EC number: ribA in B. subtilis catalyzes two reactions (GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3041#ABBREVIATION:ribB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3,4 dihydroxy-2-butanone-4-phosphate synthase#ABBREVIATION:RibBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3041)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ru5p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_db4p_c" />
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DBTSr" name="dethiobiotin synthase">
                <notes>
                    <html:p>Abbreviation: R_DBTSr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.3.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + co2 + dann &lt;==&gt; adp + dtbt + (3) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible version of DBTS</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0778#ABBREVIATION:bioD#ECNUMBERS:6.3.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dethiobiotin synthase#ABBREVIATION:BioDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0778)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_dann_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dtbt_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DCTPD" name="dCTP deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DCTPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.13</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dctp + h + h2o --&gt; dutp + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2065#ABBREVIATION:dcd#ECNUMBERS:3.5.4.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Deoxycytidine triphosphate deaminase#ABBREVIATION:Dcd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2065)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dctp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dutp_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DCYTD" name="deoxycytidine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DCYTD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.14</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dcyt + h + h2o --&gt; duri + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2143#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2143)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dcyt_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_duri_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DCYTt2" name="deoxycytidine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DCYTt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: dcyt[e] + h[e] --&gt; dcyt[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2393#ABBREVIATION:nupC#</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>NAME:NUP, nucleoside H symporter#ABBREVIATION:NupCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964) or (b2393)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dcyt_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcyt_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DDGALK" name="_2-dehydro-3-deoxygalactonokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DDGALK</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 2.7.1.58</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dh3dgal + atp --&gt; 2dh3dgal6p + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3693#ABBREVIATION:dgoK#ECNUMBERS:2.7.1.58#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-oxo-3-deoxygalactonate kinase#ABBREVIATION:DgoK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3693)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dh3dgal_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dh3dgal6p_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DDGLCNt2r" name="_2-dehydro-3-deoxy-D-gluconate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_DDGLCNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: _2ddglcn[e] + h[e] &lt;==&gt; 2ddglcn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3909#ABBREVIATION:kdgT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-keto-3-deoxy-D-gluconate transporter#ABBREVIATION:KdgT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3909)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ddglcn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddglcn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DDGLK" name="_2-dehydro-3-deoxygluconokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DDGLK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.45</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2ddglcn + atp --&gt; 2ddg6p + adp + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3526#ABBREVIATION:kdgK#ECNUMBERS:2.7.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ketodeoxygluconokinase#ABBREVIATION:KdgK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3526)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ddglcn_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddg6p_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DDPA" name="_3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DDPA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.15</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : e4p + h2o + pep --&gt; 2dda7p + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0754#ABBREVIATION:aroG#ECNUMBERS:2.5.1.54#</html:p>
                    <html:p>LOCUS:b1704#ABBREVIATION:aroH#ECNUMBERS:2.5.1.54#</html:p>
                    <html:p>LOCUS:b2601#ABBREVIATION:aroF#ECNUMBERS:2.5.1.54#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-dehydro-3-deoxyphosphoheptonate aldolase F#ABBREVIATION:AroF#</html:p>
                    <html:p>NAME:_2-dehydro-3-deoxyphosphoheptonate aldolase G#ABBREVIATION:AroGec#</html:p>
                    <html:p>NAME:_2-dehydro-3-deoxyphosphoheptonate aldolase H#ABBREVIATION:AroH#</html:p>
                    <html:p>GENE ASSOCIATION: (b2601) or (b1704) or (b0754)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_e4p_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dda7p_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DDPGALA" name="_2-dehydro-3-deoxy-6-phosphogalactonate aldolase">
                <notes>
                    <html:p>Abbreviation: R_DDPGALA</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 4.1.2.21</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dh3dgal6p &lt;==&gt; g3p + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3692#ABBREVIATION:OBSOLETE (DgoA)#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-dehydro-3-deoxygalactonate 6-phosphate aldolase#ABBREVIATION:DgoA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3692)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dh3dgal6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DGK1" name="deoxyguanylate kinase (dGMP:ATP)">
                <notes>
                    <html:p>Abbreviation: R_DGK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.8</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dgmp &lt;==&gt; adp + dgdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Added EC- JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3648#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Guanylate kinase#ABBREVIATION:Gmkec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3648)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dgmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dgdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DGSNt2" name="deoxyguanosine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DGSNt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: dgsn[e] + h[e] --&gt; dgsn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgsn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgsn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHAD1" name="dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHAD1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.9</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 23dhmb --&gt; 3mob + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3771#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3771)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23dhmb_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3mob_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHAD2" name="Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHAD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 23dhmp --&gt; 3mop + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3771#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3771)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23dhmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3mop_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHAPT" name="Dihydroxyacetone phosphotransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHAPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : dha + pep --&gt; dhap + pyr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1198#ABBREVIATION:dhaH#</html:p>
                    <html:p>LOCUS:b1199#ABBREVIATION:dhaL#</html:p>
                    <html:p>LOCUS:b1200#ABBREVIATION:dhaK#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:Dihydroxyacetone phosphotransferase Component#ABBREVIATION:DhaM#</html:p>
                    <html:p>NAME:Dihydroxyacetone phosphotransferase Component#ABBREVIATION:DhaL#</html:p>
                    <html:p>NAME:Dihydroxyacetone phosphotransferase Component#ABBREVIATION:DhaK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b1200) and (b1199) and (b2416) and (b1198)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dha_c" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHAt" name="Dihydroxyacetone transport via facilitated diffusion">
                <notes>
                    <html:p>Abbreviation: R_DHAt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: dha[e] &lt;==&gt; dha[c]</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dha_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dha_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHBD" name="_2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_DHBD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.1.28</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 23ddhb + nad &lt;==&gt; 23dhb + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0596#ABBREVIATION:entA#ECNUMBERS:1.3.1.28#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase#ABBREVIATION:EntA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0596)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23ddhb_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23dhb_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHBSr" name="_2,3-dihydroxybenzoate adenylate synthase">
                <notes>
                    <html:p>Abbreviation: R_DHBSr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.58</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 23dhb + atp &lt;==&gt; 23dhba [deleted 07/14/2004  09:51:42 AM] + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible form of DHBS</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0594#ABBREVIATION:entE#ECNUMBERS:2.7.7.58#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydroxybenzoate-AMP ligase#ABBREVIATION:EntE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0594)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23dhb_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23dhba_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHCIND" name="_2,3-dihydroxycinnamate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHCIND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : cenchddd + nad --&gt; dhcinnm + h + nadh</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR - see PMID:9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2541#ABBREVIATION:hcaB#ECNUMBERS:1.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase#ABBREVIATION:HcaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2541)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cenchddd_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhcinnm_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHCINDO" name="_2,3-dihydroxycinnamate 1,2-dioxygenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHCINDO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : dhcinnm + o2 --&gt; hkntd</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- see PMID: 9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0348#ABBREVIATION:mhpB#ECNUMBERS:1.13.11.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydroxyphenylpropionate 1,2-dioxygenase#ABBREVIATION:MhpB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0348)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhcinnm_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hkntd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHDPRy" name="dihydrodipicolinate reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHDPRy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.1.26</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : 23dhdp + h + nadph --&gt; nadp + thdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0031#ABBREVIATION:dapB#ECNUMBERS:1.3.1.26#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydrodipicolinate reductase#ABBREVIATION:DapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0031)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23dhdp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_thdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHDPS" name="dihydrodipicolinate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.52</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : aspsa + pyr --&gt; 23dhdp + h + (2) h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2478#ABBREVIATION:dapA#ECNUMBERS:4.2.1.52#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydrodipicolinate synthetase#ABBREVIATION:DapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2478)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_aspsa_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23dhdp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHFR" name="dihydrofolate reductase">
                <notes>
                    <html:p>Abbreviation: R_DHFR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.5.1.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhf + h + nadph &lt;==&gt; nadp + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0048#ABBREVIATION:folA#ECNUMBERS:1.5.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihydrofolate reductase#ABBREVIATION:FolA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0048)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhf_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHFS" name="dihydrofolate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHFS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.12</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + dhpt + glu-L --&gt; adp + dhf + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2315#ABBREVIATION:folC#ECNUMBERS:6.3.2.12,-!-,6.3.2.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:folypolyglutamate synthase and dihydrofolate synthase#ABBREVIATION:FolCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2315)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dhpt_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dhf_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHNAOT" name="_1,4-dihydroxy-2-naphthoate octaprenyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHNAOT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhna + octdp --&gt; 2dmmq8 + co2 + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC 2.5.1-; menA
Reaction is uncharged the loss of 2H (conversion from quinol to quinone form is thought to be spontaneous).</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3930#ABBREVIATION:menA#ECNUMBERS:2.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_1,4 dihydroxy-2-napthoate octaprenyltransferase#ABBREVIATION:MenA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3930)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhna_c" />
                    <speciesReference species="M_octdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHNPA2" name="dihydroneopterin aldolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHNPA2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhnpt --&gt; 6hmhpt + gcald</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- similar to DHNPA except the &amp;apos;pterin product is different</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3058#ABBREVIATION:folB#ECNUMBERS:4.1.2.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihydroneopterin aldolase#ABBREVIATION:FolB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3058)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhnpt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_6hmhpt_c" />
                    <speciesReference species="M_gcald_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHORD2" name="dihydoorotic acid dehydrogenase (quinone8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHORD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.3.1</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhor-S + q8 --&gt; orot + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0945#ABBREVIATION:pyrD#ECNUMBERS:1.3.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydroorotate dehydrogenase#ABBREVIATION:PyrD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0945)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhor_S_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_orot_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHORD5" name="dihydroorotic acid (menaquinone-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHORD5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.3.1</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhor-S + mqn8 --&gt; mql8 + orot</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0945#ABBREVIATION:pyrD#ECNUMBERS:1.3.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydroorotate dehydrogenase#ABBREVIATION:PyrD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0945)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhor_S_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_orot_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHORTS" name="dihydroorotase">
                <notes>
                    <html:p>Abbreviation: R_DHORTS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.2.3</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhor-S + h2o &lt;==&gt; cbasp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1062#ABBREVIATION:pyrC#ECNUMBERS:3.5.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydroorotase#ABBREVIATION:PyrC#</html:p>
                    <html:p>GENE ASSOCIATION: (b1062)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhor_S_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cbasp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHPPD" name="_2,3-dihydroxyphenylpropionate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHPPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : cechddd + nad --&gt; dhpppn + h + nadh</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR -see PMID 9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2541#ABBREVIATION:hcaB#ECNUMBERS:1.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase#ABBREVIATION:HcaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2541)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cechddd_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhpppn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHPPDA2" name="diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHPPDA2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.26</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 25drapp + h + h2o --&gt; 5apru + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Riboflavin-specific deaminase
AR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0414#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0414)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_25drapp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5apru_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHPS2" name="dihydropteroate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHPS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4abz + 6hmhptpp --&gt; dhpt + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- similar to DHPS except uses 6hmhptpp (has ketone rather than OH)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3177#ABBREVIATION:folP#ECNUMBERS:2.5.1.15#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Dihydropteroate synthase#ABBREVIATION:FolP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3177)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abz_c" />
                    <speciesReference species="M_6hmhptpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhpt_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHPTDCs" name="_4,5-dihydroxy-2,3-pentanedione cyclization (spontaneous)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHPTDCs</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : dhptd --&gt; h2o + hmfurn</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhptd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_hmfurn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHQD" name="_3-dehydroquinate dehydratase">
                <notes>
                    <html:p>Abbreviation: R_DHQD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.10</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 3dhq &lt;==&gt; 3dhsk + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1693#ABBREVIATION:aroD#ECNUMBERS:4.2.1.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-dehydroquinate dehydratase#ABBREVIATION:AroD#</html:p>
                    <html:p>GENE ASSOCIATION: (b1693)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3dhq_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3dhsk_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DHQS" name="_3-dehydroquinate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DHQS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.3.4</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 2dda7p --&gt; 3dhq + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previously EC 4.6.1.3. now EC 4.2.3.4, 3-dehydroquinate synthase
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3389#ABBREVIATION:aroB#ECNUMBERS:4.6.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-dehydroquinate synthase#ABBREVIATION:AroB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3389)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dda7p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3dhq_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DINSt2" name="deoxyinosine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DINSt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: din[e] + h[e] --&gt; din[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_din_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_din_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DKGLCNR1" name="_2,5-diketo-D-gluconate reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DKGLCNR1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 25dkglcn + h + nadph --&gt; 2dhguln + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0207#ABBREVIATION:dkgB#ECNUMBERS:1.1.1.274#</html:p>
                    <html:p>LOCUS:b3012#ABBREVIATION:dkgA#ECNUMBERS:1.1.1.274#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,5-diketo-D-gluconate reductase B#ABBREVIATION:DkgB#</html:p>
                    <html:p>NAME:_2,5-diketo-D-gluconate reductase A#ABBREVIATION:DkgA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0207) or (b3012)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_25dkglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dhguln_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DKGLCNR2x" name="_2,5-diketo-D-gluconate reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DKGLCNR2x</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 25dkglcn + h + nadh --&gt; 5dglcn + nad</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_25dkglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5dglcn_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DKGLCNR2y" name="_2,5-diketo-D-gluconate reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DKGLCNR2y</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 25dkglcn + h + nadph --&gt; 5dglcn + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_25dkglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5dglcn_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DKMPPD" name="_2,3-diketo-5-methylthio-1-phosphopentane degradation reaction" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DKMPPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : dkmpp + h2o + o2 --&gt; 2kmb + for + (2) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- based on B. subtilis and K. pneumoniae reactions (not sure about the h2o and h)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dkmpp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2kmb_c" />
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DKMPPD2" name="_2,3-diketo-5-methylthio-1-phosphopentane degradation reaction" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DKMPPD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : dkmpp + (3) h2o --&gt; 2kmb + for + (6) h + pi</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR- Added H2O to left side so that oxygen requirement (as in reaction DKMPPD) isn&amp;apos;t there</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dkmpp_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2kmb_c" />
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" stoichiometry="6" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMATT" name="dimethylallyltranstransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMATT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dmpp + ipdp --&gt; grdp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0421#ABBREVIATION:ispA#ECNUMBERS:2.5.1.10,-!-,2.5.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Geranyltransferase#ABBREVIATION:IspA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0421)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmpp_c" />
                    <speciesReference species="M_ipdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_grdp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMPPS" name="_1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (dmpp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMPPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h + h2mb4p + nadh --&gt; dmpp + h2o + nad</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR- unsure about cofactor stoichiometry</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0029#ABBREVIATION:ispH#ECNUMBERS:1.17.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isoprenyl-pyrophosphate synthase and dimethylallyl diphosphate#ABBREVIATION:LytB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0029)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2mb4p_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dmpp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMQMT" name="_3-Dimethylubiquinonol 3-methyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMQMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2omhmbl + amet --&gt; ahcys + h + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2232#ABBREVIATION:ubiG#ECNUMBERS:2.1.1.64#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-demethylubiquinone-9 3-methytransferase and 2-octaprenyl-6-hydroxyphenol methylase#ABBREVIATION:UbiG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2232)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2omhmbl_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMSOR1" name="Dimethyl sulfoxide reductase (Menaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMSOR1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : dmso + mql8 --&gt; dms + h2o + mqn8</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0894#ABBREVIATION:dmsA#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0895#ABBREVIATION:dmsB#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0896#ABBREVIATION:dmsC#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anaerobic dimethyl sulfoxide reductase#ABBREVIATION:DmsABC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0894 and b0896 and b0895)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmso_c" />
                    <speciesReference species="M_mql8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dms_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMSOR1e" name="Dimethyl sulfoxide reductase (Menaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMSOR1e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: dmso[e] + mql8[c] --&gt; dms[e] + h2o[e] + mqn8[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1872#ABBREVIATION:torZ#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1873#ABBREVIATION:torY#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorZ#</html:p>
                    <html:p>NAME:cytochrome c-type protein in TMAO reductase system III#ABBREVIATION:TorY#</html:p>
                    <html:p>GENE ASSOCIATION: (b1873) and (b1872)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmso_e" />
                    <speciesReference species="M_mql8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dms_e" />
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_mqn8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMSOR2" name="Dimethyl sulfoxide reductase (Demethylmenaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMSOR2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : 2dmmql8 + dmso --&gt; 2dmmq8 + dms + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0894#ABBREVIATION:dmsA#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0895#ABBREVIATION:dmsB#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0896#ABBREVIATION:dmsC#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anaerobic dimethyl sulfoxide reductase#ABBREVIATION:DmsABC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0894 and b0896 and b0895)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_dmso_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_dms_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DMSOR2e" name="Dimethyl sulfoxide reductase (Demethylmenaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DMSOR2e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: _2dmmql8[c] + dmso[e] --&gt; 2dmmq8[c] + dms[e] + h2o[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1872#ABBREVIATION:torZ#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1873#ABBREVIATION:torY#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorZ#</html:p>
                    <html:p>NAME:cytochrome c-type protein in TMAO reductase system III#ABBREVIATION:TorY#</html:p>
                    <html:p>GENE ASSOCIATION: (b1873) and (b1872)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_dmso_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_dms_e" />
                    <speciesReference species="M_h2o_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DNMPPA" name="Dihydroneopterin monophosphate dephosphorylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DNMPPA</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhpmp + h2o --&gt; dhnpt + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Neidhardt page 667</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhpmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhnpt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DNTPPA" name="Dihydroneopterin triphosphate pyrophosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DNTPPA</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ahdt + h2o --&gt; dhpmp + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Neidhardt pg 667</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0099#ABBREVIATION:mutT#ECNUMBERS:3.6.1.-#</html:p>
                    <html:p>LOCUS:b1865#ABBREVIATION:nudB#ECNUMBERS:3.6.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleoside triphosphatase#ABBREVIATION:MutT#</html:p>
                    <html:p>NAME:Dihydroneopterin triphosphate pyrophosphorylase#ABBREVIATION:NtpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0099) or (b1865)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ahdt_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhpmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DOGULNR" name="_2,3 dioxo-L-gulonate reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DOGULNR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 23doguln + h + nadh --&gt; 3dhguln + nad</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3575#ABBREVIATION:yiaK#ECNUMBERS:1.1.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3 diketogulonate dehydrogenase (putative)#ABBREVIATION:YiaK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3575)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23doguln_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3dhguln_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DPCOAK" name="dephospho-CoA kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DPCOAK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.24</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + dpcoa --&gt; adp + coa + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dpcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DPR" name="_2-dehydropantoate 2-reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DPR</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 1.1.1.169</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2dhp + h + nadph --&gt; nadp + pant-R</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0425#ABBREVIATION:panE#ECNUMBERS:1.1.1.169#</html:p>
                    <html:p>LOCUS:b3774#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvCec#</html:p>
                    <html:p>NAME:_2-dehydropantoate reductase#ABBREVIATION:PanE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0425) or (b3774)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dhp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_pant_R_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DRPA" name="deoxyribose-phosphate aldolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DRPA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.4</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dr5p --&gt; acald + g3p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4381#ABBREVIATION:deoC#ECNUMBERS:4.1.2.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deoxyribose-5-phosphate aldolase#ABBREVIATION:DeoC#</html:p>
                    <html:p>GENE ASSOCIATION: (b4381)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dr5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DSERt2r" name="D-serine transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_DSERt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ser-D[e] &lt;==&gt; h[c] + ser-D[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4208#ABBREVIATION:cycA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, D-ala/D-ser/glycine transport#ABBREVIATION:CycAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4208)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ser_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ser_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DTMPK" name="dTMP kinase">
                <notes>
                    <html:p>Abbreviation: R_DTMPK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.9</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dtmp &lt;==&gt; adp + dtdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1098#ABBREVIATION:tmk#ECNUMBERS:2.7.4.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Thymidylate kinase#ABBREVIATION:Tmk#</html:p>
                    <html:p>GENE ASSOCIATION: (b1098)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dtmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dtdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DURIK1" name="deoxyuridine kinase (ATP:Deoxyuridine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DURIK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + duri --&gt; adp + dump + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1238#ABBREVIATION:tdk#ECNUMBERS:2.7.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thimidine kinase#ABBREVIATION:Tdk#</html:p>
                    <html:p>GENE ASSOCIATION: (b1238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_duri_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dump_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DURIPP" name="deoxyuridine phosphorylase">
                <notes>
                    <html:p>Abbreviation: R_DURIPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : duri + pi &lt;==&gt; 2dr1p + ura</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4382#ABBREVIATION:deoA#ECNUMBERS:2.4.2.4#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:thymidine phosphorylase#ABBREVIATION:DeoA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4382) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_duri_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr1p_c" />
                    <speciesReference species="M_ura_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DURIt2" name="deoxyuridine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DURIt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: duri[e] + h[e] --&gt; duri[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2393#ABBREVIATION:nupC#</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>NAME:NUP, nucleoside H symporter#ABBREVIATION:NupCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964) or (b2393)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_duri_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_duri_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DUTPDP" name="dUTP diphosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DUTPDP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.23</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dutp + h2o --&gt; dump + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3640#ABBREVIATION:dut#ECNUMBERS:3.6.1.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dUTP pyrophosphatase#ABBREVIATION:Dutec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3640)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dutp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dump_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DXPRIi" name="_1-deoxy-D-xylulose reductoisomerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DXPRIi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dxyl5p + h + nadph --&gt; 2me4p + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added irreversible form of DXPRI.  EC 1.1.1.267</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0173#ABBREVIATION:dxr#ECNUMBERS:1.1.1.267#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_1-deoxy-D-xylulose 5-phosphate reductoisomerase#ABBREVIATION:Dxr#</html:p>
                    <html:p>GENE ASSOCIATION: (b0173)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dxyl5p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2me4p_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DXPS" name="_1-deoxy-D-xylulose 5-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DXPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3p + h + pyr --&gt; co2 + dxyl5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC 4.1.3.37 transferred to:
EC 2.2.1.7
NJ</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0420#ABBREVIATION:dxs#ECNUMBERS:2.2.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_1-deoxyxylulose-5-phosphate synthase#ABBREVIATION:Dxs#</html:p>
                    <html:p>GENE ASSOCIATION: (b0420)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_dxyl5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_DXYLK" name="_1-Deoxy-D-xylulose kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_DXYLK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + dxyl --&gt; adp + dxyl5p + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3564#ABBREVIATION:xylB#ECNUMBERS:2.7.1.17,-!-,2.7.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:xylulokinase#ABBREVIATION:XylB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3564)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dxyl_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dxyl5p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_D_LACt2" name="D-lactate transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_D_LACt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + lac-D[e] &lt;==&gt; h[c] + lac-D[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2975#ABBREVIATION:yghK#</html:p>
                    <html:p>LOCUS:b3603#ABBREVIATION:lldP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:LctP transporter, L-lactate/D-lactate/Glycolate H symporter#ABBREVIATION:LldP#</html:p>
                    <html:p>NAME:putative L-lactate permease, LctP family#ABBREVIATION:GlcA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2975) or (b3603)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_lac_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lac_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_E4PD" name="Erythrose 4-phosphate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_E4PD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : e4p + h2o + nad &lt;==&gt; 4per + (2) h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Reaction from KEGG R01825</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2927#ABBREVIATION:epd#ECNUMBERS:1.2.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Erythrose-4-phosphate dehydrogenase#ABBREVIATION:Epd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2927)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_e4p_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4per_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ECAP_EC" name="ECA polymerization (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ECAP_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : unagamuf --&gt; eca_EC + h + udcpdp</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_unagamuf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_eca_EC_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_udcpdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDA" name="_2-dehydro-3-deoxy-phosphogluconate aldolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.14</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : 2ddg6p --&gt; g3p + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1850#ABBREVIATION:eda#ECNUMBERS:4.1.2.16,-!-,4.1.1.3,-!-,4.1.2.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-keto-3-deoxy-6-phosphogluconate aldolase#ABBREVIATION:Eda#</html:p>
                    <html:p>GENE ASSOCIATION: (b1850)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ddg6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDD" name="_6-phosphogluconate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.12</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : 6pgc --&gt; 2ddg6p + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv, jp
it (EC number)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1851#ABBREVIATION:edd#ECNUMBERS:4.2.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_6-phosphogluconate dehydratase#ABBREVIATION:Edd#</html:p>
                    <html:p>GENE ASSOCIATION: (b1851)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_6pgc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddg6p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDTXS1" name="Endotoxin Synthesis (lauroyl transferase)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDTXS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ddcaACP + kdo2lipid4 --&gt; ACP + kdo2lipid4L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1054#ABBREVIATION:lpxL#ECNUMBERS:2.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lauroyl transferase#ABBREVIATION:LpxL#</html:p>
                    <html:p>GENE ASSOCIATION: (b1054)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ddcaACP_c" />
                    <speciesReference species="M_kdo2lipid4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_kdo2lipid4L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDTXS2" name="Endotoxin Synthesis (myristoyl transferase)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDTXS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : kdo2lipid4L + myrsACP --&gt; ACP + lipa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 1043</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1855#ABBREVIATION:lpxM#ECNUMBERS:2.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:myristoyl transferase#ABBREVIATION:MsbB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1855)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_kdo2lipid4L_c" />
                    <speciesReference species="M_myrsACP_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_lipa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDTXS3" name="Endotoxin Synthesis (palmitoleoyl ACP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDTXS3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : hdeACP + kdo2lipid4 --&gt; ACP + kdo2lipid4p</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR-see PMID 10092655</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2378#ABBREVIATION:ddg#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:palmitoleoyl-ACP acyltransferase#ABBREVIATION:LpxP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2378)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hdeACP_c" />
                    <speciesReference species="M_kdo2lipid4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_kdo2lipid4p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EDTXS4" name="Endotoxin Synthesis (myristoyl transferase)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_EDTXS4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : kdo2lipid4p + myrsACP --&gt; ACP + lipa_cold</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR see PMID 10092655</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1855#ABBREVIATION:lpxM#ECNUMBERS:2.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:myristoyl transferase#ABBREVIATION:MsbB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1855)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_kdo2lipid4p_c" />
                    <speciesReference species="M_myrsACP_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_lipa_cold_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ENO" name="enolase">
                <notes>
                    <html:p>Abbreviation: R_ENO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.11</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : 2pg &lt;==&gt; h2o + pep</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2779#ABBREVIATION:eno#ECNUMBERS:4.2.1.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:enolase#ABBREVIATION:Eno#</html:p>
                    <html:p>GENE ASSOCIATION: (b2779)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2pg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pep_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ENTCS" name="enterochelin synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ENTCS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (3) 23dhba [deleted 07/14/2004  09:51:42 AM] + (3) seramp --&gt; (6) amp + enter + (6) h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0583#ABBREVIATION:entD#ECNUMBERS:2.7.8.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:enterochelin synthetase#ABBREVIATION:EntD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0583)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_23dhba_c" stoichiometry="3" />
                    <speciesReference species="M_seramp_c" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" stoichiometry="6" />
                    <speciesReference species="M_enter_c" />
                    <speciesReference species="M_h_c" stoichiometry="6" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ETHAAL" name="Ethanolamine ammonia-lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ETHAAL</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.3.1.7</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : etha --&gt; acald + nh4</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2440#ABBREVIATION:eutC#ECNUMBERS:4.3.1.7#</html:p>
                    <html:p>LOCUS:b2441#ABBREVIATION:eutB#ECNUMBERS:4.3.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ethanolamine ammonia-lyase#ABBREVIATION:EutBC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2441 and b2440)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_etha_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ETOHt2r" name="ethanol reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ETOHt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: etoh[e] + h[e] &lt;==&gt; etoh[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_etoh_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_etoh_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_12ppd_S_e" name="(S)-Propane-1,2-diol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_12ppd_S_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 12ppd-S &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_12ppd_S_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_12ppd_S_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_15dap_e" name="_1,5-Diaminopentane exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_15dap_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 15dap &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_15dap_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_15dap_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_26dap_M_e" name="meso-2,6-Diaminoheptanedioate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_26dap_M_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 26dap-M &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_26dap_M_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_26dap_M_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_2ddglcn_e" name="_2-Dehydro-3-deoxy-D-gluconate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_2ddglcn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 2ddglcn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ddglcn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddglcn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_3hcinnm_e" name="_3-hydroxycinnamic acid exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_3hcinnm_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 3hcinnm &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hcinnm_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3hcinnm_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_3hpppn_e" name="_3-(3-hydroxy-phenyl)propionate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_3hpppn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 3hpppn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hpppn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3hpppn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_4abut_e" name="_4-Aminobutanoate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_4abut_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : 4abut &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abut_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abut_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ac_e" name="Acetate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ac_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ac &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ac_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_acac_e" name="Acetoacetate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_acac_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : acac &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acac_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acac_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_acald_e" name="Acetaldehyde exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_acald_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : acald &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acald_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_acgam_e" name="N-Acetyl-D-glucosamine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_acgam_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : acgam &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acgam_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acgam_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_acmana_e" name="N-Acetyl-D-mannosamine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_acmana_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : acmana &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acmana_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acmana_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_acnam_e" name="N-Acetylneuraminate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_acnam_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : acnam &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acnam_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acnam_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ade_e" name="Adenine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ade_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ade &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ade_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ade_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_adn_e" name="Adenosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_adn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : adn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_akg_e" name="_2-Oxoglutarate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_akg_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : akg &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ala_D_e" name="D-Alanine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ala_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ala-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ala_L_e" name="L-Alanine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ala_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ala-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ala_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_alltn_e" name="Allantoin exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_alltn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : alltn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alltn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_alltn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_amp_e" name="AMP exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_amp_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : amp &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_arab_L_e" name="L-Arabinose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_arab_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : arab-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arab_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_arab_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_arg_L_e" name="L-Arginine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_arg_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : arg-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_arg_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_arg_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_asn_L_e" name="L-Asparagine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_asn_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : asn-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asn_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asn_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_asp_L_e" name="L-Aspartate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_asp_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : asp-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_asp_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_asp_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_but_e" name="Butyrate (n-C4:0) exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_but_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : but &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_but_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_but_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_cbl1_e" name="Cob(I)alamin exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_cbl1_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : cbl1 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cbl1_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cbl1_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_chol_e" name="Choline exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_chol_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : chol &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chol_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_chol_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_cit_e" name="Citrate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_cit_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : cit &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cit_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cit_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_co2_e" name="CO2 exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_co2_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : co2 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_co2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_crn_e" name="L-Carnitine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_crn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : crn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_crn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_crn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_csn_e" name="Cytosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_csn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : csn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_csn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_csn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_cynt_e" name="Cyanate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_cynt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : cynt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cynt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cynt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_cys_L_e" name="L-Cysteine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_cys_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : cys-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cys_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cys_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_cytd_e" name="Cytidine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_cytd_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : cytd &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cytd_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cytd_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dad_2_e" name="Deoxyadenosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dad_2_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dad-2 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dad_2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dad_2_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dcyt_e" name="Deoxycytidine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dcyt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dcyt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dcyt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcyt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dgsn_e" name="Deoxyguanosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dgsn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dgsn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgsn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgsn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dha_e" name="Dihydroxyacetone exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dha_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dha &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dha_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dha_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_din_e" name="Deoxyinosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_din_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : din &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_din_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_din_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dms_e" name="Dimethyl sulfide exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dms_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dms &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dms_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dms_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_dmso_e" name="Dimethyl sulfoxide exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_dmso_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : dmso &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmso_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dmso_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_duri_e" name="Deoxyuridine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_duri_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : duri &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_duri_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_duri_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_etoh_e" name="Ethanol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_etoh_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : etoh &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_etoh_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_etoh_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_fe2_e" name="Fe2+ exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_fe2_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : fe2 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fe2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fe2_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_for_e" name="Formate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_for_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : for &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_for_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_for_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_fru_e" name="D-Fructose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_fru_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : fru &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fru_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fru_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_fuc1p_L_e" name="L-Fucose 1-phosphate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_fuc1p_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : fuc1p-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fuc1p_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fuc1p_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_fuc_L_e" name="L-Fucose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_fuc_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : fuc-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fuc_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fuc_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_fum_e" name="Fumarate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_fum_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : fum &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_g6p_e" name="D-Glucose 6-phosphate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_g6p_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : g6p &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g6p_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gal_e" name="D-Galactose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gal_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gal &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gal_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gal_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_galct_D_e" name="D-Galactarate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_galct_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : galct-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galct_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galct_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_galctn_D_e" name="D-Galactonate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_galctn_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : galctn-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galctn_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galctn_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_galt_e" name="Galactitol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_galt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : galt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_galur_e" name="D-Galacturonate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_galur_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : galur &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galur_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galur_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gam_e" name="D-Glucosamine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gam_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gam &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gam_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gam_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gbbtn_e" name="gamma-butyrobetaine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gbbtn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gbbtn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gbbtn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gbbtn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glc_e" name="D-Glucose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glc_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glc-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glc_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glcn_e" name="D-Gluconate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glcn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glcn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glcr_e" name="D-Glucarate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glcr_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glcr &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcr_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glcur_e" name="D-Glucuronate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glcur_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glcur &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcur_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcur_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gln_L_e" name="L-Glutamine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gln_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gln-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gln_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gln_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glu_L_e" name="L-Glutamate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glu_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glu-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gly_e" name="Glycine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gly_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gly &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gly_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gly_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glyald_e" name="D-Glyceraldehyde exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glyald_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glyald &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyald_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyald_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glyb_e" name="Glycine betaine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glyb_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glyb &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyb_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyb_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glyc3p_e" name="Glycerol 3-phosphate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glyc3p_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glyc3p &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc3p_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glyc_e" name="Glycerol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glyc_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glyc &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_glyclt_e" name="Glycolate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_glyclt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : glyclt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyclt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gsn_e" name="Guanosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gsn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gsn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gsn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gsn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_gua_e" name="Guanine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_gua_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : gua &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gua_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gua_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_h2o_e" name="H2O exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_h2o_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : h2o &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_h_e" name="H+ exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_h_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : h &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_hdca_e" name="Hexadecanoate (n-C16:0) exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_hdca_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : hdca &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hdca_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_his_L_e" name="L-Histidine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_his_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : his-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_his_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_his_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_hxan_e" name="Hypoxanthine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_hxan_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : hxan &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hxan_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hxan_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_idon_L_e" name="L-Idonate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_idon_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : idon-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_idon_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_idon_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ile_L_e" name="L-Isoleucine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ile_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ile-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ile_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ile_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_indole_e" name="Indole exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_indole_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : indole &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_indole_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_indole_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ins_e" name="Inosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ins_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ins &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ins_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ins_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_k_e" name="K+ exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_k_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : k &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_k_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_k_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_lac_D_e" name="D-lactate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_lac_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : lac-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_lac_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_lac_L_e" name="L-Lactate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_lac_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : lac-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_lac_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_lcts_e" name="Lactose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_lcts_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : lcts &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lcts_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_lcts_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_leu_L_e" name="L-Leucine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_leu_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : leu-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_leu_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_leu_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_lys_L_e" name="L-Lysine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_lys_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : lys-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lys_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_lys_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_mal_L_e" name="L-Malate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_mal_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : mal-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mal_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_malt_e" name="Maltose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_malt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : malt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_malt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_malthx_e" name="Maltohexaose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_malthx_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : malthx &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malthx_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_malthx_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_maltpt_e" name="Maltopentaose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_maltpt_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : maltpt &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_maltpt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_maltpt_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_malttr_e" name="Maltotriose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_malttr_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : malttr &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malttr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_malttr_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_maltttr_e" name="Maltotetraose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_maltttr_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : maltttr &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_maltttr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_maltttr_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_man6p_e" name="D-Mannose 6-phosphate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_man6p_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : man6p &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man6p_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_man6p_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_man_e" name="D-Mannose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_man_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : man &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_man_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_melib_e" name="Melibiose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_melib_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : melib &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_melib_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_melib_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_met_D_e" name="D-Methionine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_met_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : met-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_met_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_met_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_met_L_e" name="L-Methionine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_met_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : met-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_met_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_met_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_mnl_e" name="D-Mannitol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_mnl_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : mnl &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mnl_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mnl_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_na1_e" name="Sodium exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_na1_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : na1 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_na1_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_na1_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_nac_e" name="Nicotinate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_nac_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : nac &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nac_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nac_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_nad_e" name="Nicotinamide adenine dinucleotide exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_nad_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : nad &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nad_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nad_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_nh4_e" name="Ammonia exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_nh4_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : nh4 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nh4_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_nmn_e" name="NMN exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_nmn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : nmn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nmn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nmn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_no2_e" name="Nitrite exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_no2_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : no2 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_no2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_no2_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_no3_e" name="Nitrate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_no3_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : no3 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_no3_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_no3_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_o2_e" name="O2 exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_o2_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : o2 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_o2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_o2_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ocdca_e" name="octadecanoate (n-C18:0) exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ocdca_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ocdca &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ocdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ocdca_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_orn_e" name="Ornithine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_orn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : orn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_orn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_orn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_phe_L_e" name="L-Phenylalanine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_phe_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : phe-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_phe_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_phe_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_pi_e" name="Phosphate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_pi_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : pi &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pi_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_pnto_R_e" name="(R)-Pantothenate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_pnto_R_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : pnto-R &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pnto_R_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pnto_R_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_pppn_e" name="Phenylpropanoate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_pppn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : pppn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pppn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pppn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_pro_L_e" name="L-Proline exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_pro_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : pro-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pro_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pro_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ptrc_e" name="Putrescine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ptrc_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ptrc &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ptrc_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ptrc_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_pyr_e" name="Pyruvate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_pyr_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : pyr &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pyr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_rib_D_e" name="D-Ribose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_rib_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : rib-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_rib_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_rib_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_rmn_e" name="L-Rhamnose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_rmn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : rmn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_rmn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_rmn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_sbt_D_e" name="D-Sorbitol exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_sbt_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : sbt-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_sbt_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_sbt_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ser_D_e" name="D-Serine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ser_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ser-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ser_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ser_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ser_L_e" name="L-Serine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ser_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ser-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ser_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ser_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_so4_e" name="Sulfate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_so4_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : so4 &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_so4_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_so4_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_spmd_e" name="Spermidine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_spmd_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : spmd &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_spmd_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_spmd_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_succ_e" name="Succinate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_succ_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : succ &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_succ_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_succ_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_sucr_e" name="Sucrose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_sucr_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : sucr &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_sucr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_sucr_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tartr_L_e" name="L-tartrate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tartr_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tartr-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tartr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tartr_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_taur_e" name="Taurine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_taur_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : taur &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_taur_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_taur_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_thm_e" name="Thiamin exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_thm_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : thm &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_thm_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_thm_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_thr_L_e" name="L-Threonine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_thr_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : thr-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_thr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_thr_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_thymd_e" name="Thymidine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_thymd_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : thymd &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_thymd_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_thymd_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tma_e" name="Trimethylamine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tma_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tma &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tma_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tma_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tmao_e" name="Trimethylamine N-oxide exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tmao_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tmao &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tmao_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tmao_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tre_e" name="Trehalose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tre_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tre &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tre_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tre_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_trp_L_e" name="L-Tryptophan exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_trp_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : trp-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_trp_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_trp_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tsul_e" name="Thiosulfate exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tsul_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tsul &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tsul_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tsul_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ttdca_e" name="tetradecanoate (n-C14:0) exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ttdca_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ttdca &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ttdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ttdca_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_tyr_L_e" name="L-Tyrosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_tyr_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : tyr-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tyr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tyr_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_ura_e" name="Uracil exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_ura_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : ura &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ura_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ura_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_urea_e" name="Urea exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_urea_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : urea &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_urea_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_urea_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_uri_e" name="Uridine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_uri_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : uri &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uri_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_uri_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_val_L_e" name="L-Valine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_val_L_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : val-L &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_val_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_val_L_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_xan_e" name="Xanthine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_xan_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : xan &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xan_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xan_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_xtsn_e" name="Xanthosine exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_xtsn_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : xtsn &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xtsn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xtsn_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_EX_xyl_D_e" name="D-Xylose exchange">
                <notes>
                    <html:p>Abbreviation: R_EX_xyl_D_e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>Equation: [e] : xyl-D &lt;==&gt;</html:p>
                    <html:p>Confidence Level: </html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xyl_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xyl_D_b" />
                </listOfProducts>
            </reaction>
            <reaction id="R_F6PA" name="fructose 6-phosphate aldolase">
                <notes>
                    <html:p>Abbreviation: R_F6PA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : f6p &lt;==&gt; dha + g3p</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0825#ABBREVIATION:fsaA#ECNUMBERS:4.1.2.-#</html:p>
                    <html:p>LOCUS:b3946#ABBREVIATION:fsaB#ECNUMBERS:4.1.2.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Fructose 6-phosphate aldolase#ABBREVIATION:Fsa#</html:p>
                    <html:p>NAME:fructose 6-phosphate aldolase#ABBREVIATION:TalC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0825) or (b3946)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_f6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dha_c" />
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FAO1" name="Fatty acid oxidation (tetradecanoate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FAO1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : atp + (7) coa + (6) fad + (6) h2o + (6) nad + ttdca --&gt; (7) accoa + amp + (6) fadh2 + (6) h + (6) nadh + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0221#ABBREVIATION:fadE#ECNUMBERS:1.3.99.3#</html:p>
                    <html:p>LOCUS:b1805#ABBREVIATION:fadD#ECNUMBERS:6.2.1.3#</html:p>
                    <html:p>LOCUS:b3845#ABBREVIATION:fadA#ECNUMBERS:2.3.1.16#</html:p>
                    <html:p>LOCUS:b3846#ABBREVIATION:fadB#ECNUMBERS:5.3.3.8,-!-,4.2.1.17,-!-,5.1.2.3,-!-,1.1.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Long-chain-fatty-acid--CoA ligase#ABBREVIATION:FadD#</html:p>
                    <html:p>NAME:_3-ketoacyl-CoA thiolase#ABBREVIATION:FadA#</html:p>
                    <html:p>NAME:_3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA-isomerase and enoyl-Coa Hydratase#ABBREVIATION:FadB#</html:p>
                    <html:p>NAME:acyl-coA dehydrogenase#ABBREVIATION:FadE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1805) and (b3845) and (b0221) and (b3846)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" stoichiometry="7" />
                    <speciesReference species="M_fad_c" stoichiometry="6" />
                    <speciesReference species="M_h2o_c" stoichiometry="6" />
                    <speciesReference species="M_nad_c" stoichiometry="6" />
                    <speciesReference species="M_ttdca_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" stoichiometry="7" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_fadh2_c" stoichiometry="6" />
                    <speciesReference species="M_h_c" stoichiometry="6" />
                    <speciesReference species="M_nadh_c" stoichiometry="6" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FAO2" name="Fatty acid oxidation (n-C16:0)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FAO2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : atp + (8) coa + (7) fad + (7) h2o + hdca + (7) nad --&gt; (8) accoa + amp + (7) fadh2 + (7) h + (7) nadh + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0221#ABBREVIATION:fadE#ECNUMBERS:1.3.99.3#</html:p>
                    <html:p>LOCUS:b1805#ABBREVIATION:fadD#ECNUMBERS:6.2.1.3#</html:p>
                    <html:p>LOCUS:b3845#ABBREVIATION:fadA#ECNUMBERS:2.3.1.16#</html:p>
                    <html:p>LOCUS:b3846#ABBREVIATION:fadB#ECNUMBERS:5.3.3.8,-!-,4.2.1.17,-!-,5.1.2.3,-!-,1.1.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Long-chain-fatty-acid--CoA ligase#ABBREVIATION:FadD#</html:p>
                    <html:p>NAME:_3-ketoacyl-CoA thiolase#ABBREVIATION:FadA#</html:p>
                    <html:p>NAME:_3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA-isomerase and enoyl-Coa Hydratase#ABBREVIATION:FadB#</html:p>
                    <html:p>NAME:acyl-coA dehydrogenase#ABBREVIATION:FadE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1805) and (b3845) and (b0221) and (b3846)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" stoichiometry="8" />
                    <speciesReference species="M_fad_c" stoichiometry="7" />
                    <speciesReference species="M_h2o_c" stoichiometry="7" />
                    <speciesReference species="M_hdca_c" />
                    <speciesReference species="M_nad_c" stoichiometry="7" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" stoichiometry="8" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_fadh2_c" stoichiometry="7" />
                    <speciesReference species="M_h_c" stoichiometry="7" />
                    <speciesReference species="M_nadh_c" stoichiometry="7" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FAO3" name="Fatty acid oxidation (octadecanoate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FAO3</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : atp + (9) coa + (8) fad + (8) h2o + (8) nad + ocdca --&gt; (9) accoa + amp + (8) fadh2 + (8) h + (8) nadh + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0221#ABBREVIATION:fadE#ECNUMBERS:1.3.99.3#</html:p>
                    <html:p>LOCUS:b1805#ABBREVIATION:fadD#ECNUMBERS:6.2.1.3#</html:p>
                    <html:p>LOCUS:b3845#ABBREVIATION:fadA#ECNUMBERS:2.3.1.16#</html:p>
                    <html:p>LOCUS:b3846#ABBREVIATION:fadB#ECNUMBERS:5.3.3.8,-!-,4.2.1.17,-!-,5.1.2.3,-!-,1.1.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Long-chain-fatty-acid--CoA ligase#ABBREVIATION:FadD#</html:p>
                    <html:p>NAME:_3-ketoacyl-CoA thiolase#ABBREVIATION:FadA#</html:p>
                    <html:p>NAME:_3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA-isomerase and enoyl-Coa Hydratase#ABBREVIATION:FadB#</html:p>
                    <html:p>NAME:acyl-coA dehydrogenase#ABBREVIATION:FadE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1805) and (b3845) and (b0221) and (b3846)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" stoichiometry="9" />
                    <speciesReference species="M_fad_c" stoichiometry="8" />
                    <speciesReference species="M_h2o_c" stoichiometry="8" />
                    <speciesReference species="M_nad_c" stoichiometry="8" />
                    <speciesReference species="M_ocdca_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" stoichiometry="9" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_fadh2_c" stoichiometry="8" />
                    <speciesReference species="M_h_c" stoichiometry="8" />
                    <speciesReference species="M_nadh_c" stoichiometry="8" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FAO4" name="fatty acid oxidation (Butanoyl-CoA )" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FAO4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : btcoa + fad + h2o + nad --&gt; aacoa + fadh2 + h + nadh</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0221#ABBREVIATION:fadE#ECNUMBERS:1.3.99.3#</html:p>
                    <html:p>LOCUS:b3846#ABBREVIATION:fadB#ECNUMBERS:5.3.3.8,-!-,4.2.1.17,-!-,5.1.2.3,-!-,1.1.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA-isomerase and enoyl-Coa Hydratase#ABBREVIATION:FadB#</html:p>
                    <html:p>NAME:acyl-coA dehydrogenase#ABBREVIATION:FadE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0221) and (b3846)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_btcoa_c" />
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aacoa_c" />
                    <speciesReference species="M_fadh2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FBA" name="fructose-bisphosphate aldolase">
                <notes>
                    <html:p>Abbreviation: R_FBA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.13</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : fdp &lt;==&gt; dhap + g3p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1773#ABBREVIATION:ydjI#</html:p>
                    <html:p>LOCUS:b2097#ABBREVIATION:fbaB#ECNUMBERS:4.1.2.13#</html:p>
                    <html:p>LOCUS:b2925#ABBREVIATION:fbaA#ECNUMBERS:4.1.2.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:fructose-bisphosphate aldolase II#ABBREVIATION:FbaA#</html:p>
                    <html:p>NAME:fructose-bisphosphate aldolase#ABBREVIATION:FbaB#</html:p>
                    <html:p>NAME:putative fructose-bisphosphate aldolase#ABBREVIATION:B1773#</html:p>
                    <html:p>GENE ASSOCIATION: (b1773) or (b2097) or (b2925)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FBP" name="fructose-bisphosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FBP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.11</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : fdp + h2o --&gt; f6p + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4232#ABBREVIATION:fbp#ECNUMBERS:3.1.3.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:fructose-1,6-bisphophatase#ABBREVIATION:Fbp#</html:p>
                    <html:p>GENE ASSOCIATION: (b4232)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fdp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FCI" name="L-fucose isomerase">
                <notes>
                    <html:p>Abbreviation: R_FCI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.25</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : fuc-L &lt;==&gt; fcl-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2802#ABBREVIATION:fucI#ECNUMBERS:5.3.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-fucose isomerase#ABBREVIATION:FucI#</html:p>
                    <html:p>GENE ASSOCIATION: (b2802)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fuc_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fcl_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FCLK" name="L-fuculokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FCLK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.51</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + fcl-L --&gt; adp + fc1p + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- had to add a proton to make it balance</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2803#ABBREVIATION:fucK#ECNUMBERS:2.7.1.51#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-fuculokinase#ABBREVIATION:FucK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2803)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_fcl_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fc1p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FCLPA" name="L-fuculose 1-phosphate aldolase">
                <notes>
                    <html:p>Abbreviation: R_FCLPA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.17</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : fc1p &lt;==&gt; dhap + lald-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2800#ABBREVIATION:fucA#ECNUMBERS:4.1.2.17#</html:p>
                    <html:p>LOCUS:b2738#ABBREVIATION:ygbL#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-fuculose-1-phosphate aldolase#ABBREVIATION:FucA#</html:p>
                    <html:p>NAME:putative fuculose phosphate aldolase#ABBREVIATION:YgbL#</html:p>
                    <html:p>GENE ASSOCIATION: (b2800) or (b2738)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fc1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_lald_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FCLT" name="Ferrochelatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FCLT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.99.1.1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : fe2 + ppp9 --&gt; (2) h + pheme</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
added Fe2+ to reactants and 2H+ to products</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0475#ABBREVIATION:hemH#ECNUMBERS:4.99.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ferrochelatase#ABBREVIATION:HemH#</html:p>
                    <html:p>GENE ASSOCIATION: (b0475)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fe2_c" />
                    <speciesReference species="M_ppp9_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pheme_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FDH2" name="formate dehydrogenase (quinone-8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FDH2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.2.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: for[c] + (3) h[c] + q8[c] --&gt; co2[c] + (2) h[e] + q8h2[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1474#ABBREVIATION:fdnG#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>LOCUS:b1475#ABBREVIATION:fdnH#</html:p>
                    <html:p>LOCUS:b1476#ABBREVIATION:fdnI#</html:p>
                    <html:p>LOCUS:b3892#ABBREVIATION:fdoI#</html:p>
                    <html:p>LOCUS:b3893#ABBREVIATION:fdoH#</html:p>
                    <html:p>LOCUS:b3894#ABBREVIATION:fdoG#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>LOCUS:b4079#ABBREVIATION:fdhF#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:formate dehydrogenase N#ABBREVIATION:Fdn#</html:p>
                    <html:p>NAME:formate dehydrogenase O#ABBREVIATION:Fdoec#</html:p>
                    <html:p>NAME:formate dehydrogenase H#ABBREVIATION:FdhF#</html:p>
                    <html:p>GENE ASSOCIATION: (b1476 and b1474 and b1475) or (b4079) or (b3892 and b3894 and b3893)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FDH3" name="Formate Dehydrogenase (menaquinone-8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FDH3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.2.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: for[c] + (3) h[c] + mqn8[c] --&gt; co2[c] + (2) h[e] + mql8[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1474#ABBREVIATION:fdnG#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>LOCUS:b1475#ABBREVIATION:fdnH#</html:p>
                    <html:p>LOCUS:b1476#ABBREVIATION:fdnI#</html:p>
                    <html:p>LOCUS:b3892#ABBREVIATION:fdoI#</html:p>
                    <html:p>LOCUS:b3893#ABBREVIATION:fdoH#</html:p>
                    <html:p>LOCUS:b3894#ABBREVIATION:fdoG#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:formate dehydrogenase N#ABBREVIATION:Fdn#</html:p>
                    <html:p>NAME:formate dehydrogenase O#ABBREVIATION:Fdoec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3892 and b3894 and b3893) or (b1476 and b1474 and b1475)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_mql8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FE2abc" name="iron (II) transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FE2abc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + fe2[e] + h2o[c] --&gt; adp[c] + fe2[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3409#ABBREVIATION:feoB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Iron(II) transport protein#ABBREVIATION:FeoB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3409)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_fe2_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fe2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FFSD" name="beta-fructofuranosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FFSD</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 3.2.1.26</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + suc6p --&gt; fru + g6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_suc6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fru_c" />
                    <speciesReference species="M_g6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FHL" name="Formate-hydrogen lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FHL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : for + h --&gt; co2 + h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 268</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2719#ABBREVIATION:hycG#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b2720#ABBREVIATION:hycF#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2721#ABBREVIATION:hycE#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2722#ABBREVIATION:hycD#</html:p>
                    <html:p>LOCUS:b2723#ABBREVIATION:hycC#</html:p>
                    <html:p>LOCUS:b2724#ABBREVIATION:hycB#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b4079#ABBREVIATION:fdhF#ECNUMBERS:1.2.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:formate dehydrogenase H#ABBREVIATION:FdhF#</html:p>
                    <html:p>NAME:hydrogenase III#ABBREVIATION:HycB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4079) and (b2721 and b2723 and b2724 and b2722 and b2720 and b2719)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FMNAT" name="FMN adenylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FMNAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.2</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + fmn + h --&gt; fad + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0025#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibFec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0025)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_fmn_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FORt" name="formate transport via diffusion">
                <notes>
                    <html:p>Abbreviation: R_FORt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: for[e] &lt;==&gt; for[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
renamed from FORTR to FORt
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0904#ABBREVIATION:focA#</html:p>
                    <html:p>LOCUS:b2492#ABBREVIATION:focB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:FNT, formate transporter#ABBREVIATION:FocA#</html:p>
                    <html:p>NAME:putative formate transporter, FNT#ABBREVIATION:FocB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2492) or (b0904)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_for_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_for_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FRD2" name="fumarate reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FRD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.99.1</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : fum + mql8 --&gt; mqn8 + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- E.coli uses menaquinone and demethylmenaquinone instead of ubiquinone</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4151#ABBREVIATION:frdD#</html:p>
                    <html:p>LOCUS:b4152#ABBREVIATION:frdC#</html:p>
                    <html:p>LOCUS:b4153#ABBREVIATION:frdB#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>LOCUS:b4154#ABBREVIATION:frdA#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:fumarate reductase#ABBREVIATION:Frd#</html:p>
                    <html:p>GENE ASSOCIATION: (b4151 and b4154 and b4153 and b4152)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_mql8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FRD3" name="fumarate reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FRD3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.99.1</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : 2dmmql8 + fum --&gt; 2dmmq8 + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- E.coli uses menaquinone and demethylmenaquinone instead of ubiquinone</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4151#ABBREVIATION:frdD#</html:p>
                    <html:p>LOCUS:b4152#ABBREVIATION:frdC#</html:p>
                    <html:p>LOCUS:b4153#ABBREVIATION:frdB#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>LOCUS:b4154#ABBREVIATION:frdA#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:fumarate reductase#ABBREVIATION:Frd#</html:p>
                    <html:p>GENE ASSOCIATION: (b4151 and b4154 and b4153 and b4152)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_fum_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FRUK" name="fructose-1-phosphate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FRUK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.56</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + f1p --&gt; adp + fdp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2168#ABBREVIATION:fruK#ECNUMBERS:2.7.1.56#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_1-phosphofructokinase#ABBREVIATION:FruK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2168)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_f1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fdp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FRUpts" name="D-fructose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FRUpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fru[e] + pep[c] --&gt; f1p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2167#ABBREVIATION:fruA#</html:p>
                    <html:p>LOCUS:b2169#ABBREVIATION:fruB#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, fructose-specific IIB'BC#ABBREVIATION:FruAec#</html:p>
                    <html:p>NAME:PTS, fructose specific enzyme IIA/FPr#ABBREVIATION:FruBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b2167) and (b2169)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fru_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f1p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FRUpts2" name="Fructose transport via PEP:Pyr PTS (f6p generating)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FRUpts2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fru[e] + pep[c] --&gt; f6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1817#ABBREVIATION:manX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1818#ABBREVIATION:manY#</html:p>
                    <html:p>LOCUS:b1819#ABBREVIATION:manZ#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, mannose IIA#ABBREVIATION:ManX#</html:p>
                    <html:p>NAME:PTS, mannose IIC#ABBREVIATION:ManY#</html:p>
                    <html:p>NAME:PTS, mannose IID#ABBREVIATION:ManZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b1818) and (b1819) and (b1817)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fru_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FTHFD" name="formyltetrahydrofolate deformylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FTHFD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.10</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : 10fthf + h2o --&gt; for + h + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1232#ABBREVIATION:purU#ECNUMBERS:3.5.1.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Formyltetrahydrofolate deformylase#ABBREVIATION:PurUec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1232)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_10fthf_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FUCPt6_2" name="Fucose 1-phosphate transport via phosphate antiport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FUCPt6_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fuc1p-L[e] + (2) pi[c] --&gt; fuc1p-L[c] + (2) pi[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3666#ABBREVIATION:uhpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, hexose phosphate:phosphate transporter#ABBREVIATION:UhpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3666)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fuc1p_L_e" />
                    <speciesReference species="M_pi_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fuc1p_L_c" />
                    <speciesReference species="M_pi_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FUCt" name="L-fucose transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_FUCt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fuc-L[e] + h[e] &lt;==&gt; fuc-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2801#ABBREVIATION:fucP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, fucose#ABBREVIATION:FucP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2801)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fuc_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fuc_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FUM" name="fumarase">
                <notes>
                    <html:p>Abbreviation: R_FUM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.2</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : fum + h2o &lt;==&gt; mal-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1611#ABBREVIATION:fumC#ECNUMBERS:4.2.1.2#</html:p>
                    <html:p>LOCUS:b1612#ABBREVIATION:fumA#ECNUMBERS:4.2.1.2#</html:p>
                    <html:p>LOCUS:b4122#ABBREVIATION:fumB#ECNUMBERS:4.2.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:fumarase A#ABBREVIATION:FumA#</html:p>
                    <html:p>NAME:fumarase B#ABBREVIATION:FumB#</html:p>
                    <html:p>NAME:fumarase C#ABBREVIATION:FumCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1612) or (b1611) or (b4122)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mal_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FUMt2_2" name="Fumarate transport via proton symport (2 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FUMt2_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fum[e] + (2) h[e] --&gt; fum[c] + (2) h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3528#ABBREVIATION:dctA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3528)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_e" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_FUMt2_3" name="Fumarate transport via proton symport (3 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_FUMt2_3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fum[e] + (3) h[e] --&gt; fum[c] + (3) h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0621#ABBREVIATION:dcuC#</html:p>
                    <html:p>LOCUS:b4123#ABBREVIATION:dcuB#</html:p>
                    <html:p>LOCUS:b4138#ABBREVIATION:dcuA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Anaerobic C4-dicarboxylate transporter protein#ABBREVIATION:DcuA#</html:p>
                    <html:p>NAME:anaerobic C4-dicarboxylate transporter#ABBREVIATION:DcuB#</html:p>
                    <html:p>NAME:dicarboxylate transporter#ABBREVIATION:DcuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b4123) or (b0621) or (b4138)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_e" />
                    <speciesReference species="M_h_e" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_h_c" stoichiometry="3" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G1PACT" name="glucosamine-1-phosphate N-acetyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G1PACT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.157</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : accoa + gam1p --&gt; acgam1p + coa + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3730#ABBREVIATION:glmU#ECNUMBERS:2.7.7.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglucosamine-1-phosphate-uridyltransferase#ABBREVIATION:GlmUec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3730)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_gam1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acgam1p_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G1PP" name="Glucose-1-phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G1PP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.10</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : g1p + h2o --&gt; glc-D + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1002#ABBREVIATION:agp#ECNUMBERS:3.1.3.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucose-1-phosphatase#ABBREVIATION:Agp#</html:p>
                    <html:p>GENE ASSOCIATION: (b1002)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G1PTT" name="glucose-1-phosphate thymidylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G1PTT</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 2.7.7.24</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dttp + g1p + h --&gt; dtdpglu + ppi</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2039#ABBREVIATION:rfbA#ECNUMBERS:2.7.7.24#</html:p>
                    <html:p>LOCUS:b3789#ABBREVIATION:rffH#ECNUMBERS:2.7.7.24#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-glucose pyrophosphorylase#ABBREVIATION:RfbA#</html:p>
                    <html:p>NAME:glucose-1-phosphate thymidylyltransferase#ABBREVIATION:RffH#</html:p>
                    <html:p>GENE ASSOCIATION: (b3789) or (b2039)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dttp_c" />
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtdpglu_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G1SATi" name="glutamate-1-semialdehyde aminotransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G1SATi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.3.8</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : glu1sa --&gt; 5aop</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- irreversible form of G1SAT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0154#ABBREVIATION:hemL#ECNUMBERS:5.4.3.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glutamte-1-semialdehyde aminotransferase#ABBREVIATION:HemLec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0154)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu1sa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5aop_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G3PD2" name="glycerol-3-phosphate dehydrogenase (NADP)">
                <notes>
                    <html:p>Abbreviation: R_G3PD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.94</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glyc3p + nadp &lt;==&gt; dhap + h + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3608#ABBREVIATION:gpsA#ECNUMBERS:1.1.1.94#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerol-3-phosphate dehydrogenase, NAD(P)+ dependent#ABBREVIATION:GpsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3608)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G3PD5" name="glycerol-3-phosphate dehydrogenase (ubiquinone-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G3PD5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.99.5</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : glyc3p + q8 --&gt; dhap + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2242#ABBREVIATION:glpB#</html:p>
                    <html:p>LOCUS:b2243#ABBREVIATION:glpC#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>LOCUS:b2241#ABBREVIATION:glpA#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>LOCUS:b3426#ABBREVIATION:glpD#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycerol-3-phosphate dehydrogenase#ABBREVIATION:GlpD#</html:p>
                    <html:p>NAME:glycerol-3-phosphate dehydrogenase (anaerobic)#ABBREVIATION:GlpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2242 and b2241 and b2243) or (b3426)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G3PD6" name="glycerol-3-phosphate dehydrogenase (menaquinone-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G3PD6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.99.5</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : glyc3p + mqn8 --&gt; dhap + mql8</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2242#ABBREVIATION:glpB#</html:p>
                    <html:p>LOCUS:b2243#ABBREVIATION:glpC#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>LOCUS:b2241#ABBREVIATION:glpA#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycerol-3-phosphate dehydrogenase (anaerobic)#ABBREVIATION:GlpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2242 and b2241 and b2243)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_mql8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G3PD7" name="glycerol-3-phosphate dehydrogenase (demethylmenaquinone-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G3PD7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.99.5</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : 2dmmq8 + glyc3p --&gt; 2dmmql8 + dhap</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2242#ABBREVIATION:glpB#</html:p>
                    <html:p>LOCUS:b2243#ABBREVIATION:glpC#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>LOCUS:b2241#ABBREVIATION:glpA#ECNUMBERS:1.1.99.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycerol-3-phosphate dehydrogenase (anaerobic)#ABBREVIATION:GlpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2242 and b2241 and b2243)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_glyc3p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_dhap_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G5SADs" name="L-glutamate 5-semialdehyde dehydratase (spontaneous)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G5SADs</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : glu5sa --&gt; 1pyr5c + h + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Needed in L-proline biosynthesis</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu5sa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_1pyr5c_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G5SD" name="glutamate-5-semialdehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G5SD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.41</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : glu5p + h + nadph --&gt; glu5sa + nadp + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0243#ABBREVIATION:proA#ECNUMBERS:1.2.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:gamma-glutamylphosphate reductase#ABBREVIATION:ProA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0243)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu5p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu5sa_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G6PDA" name="glucosamine-6-phosphate deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G6PDA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.99.6</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : gam6p + h2o --&gt; f6p + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previously EC 5.3.1.10</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0678#ABBREVIATION:nagB#ECNUMBERS:3.5.99.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucosamine-6-phosphate deaminase#ABBREVIATION:NagB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0678)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gam6p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G6PDH2r" name="glucose 6-phosphate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_G6PDH2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.49</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : g6p + nadp &lt;==&gt; 6pgl + h + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - a reversible reaction that is otherwise identical to ZWF
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1852#ABBREVIATION:zwf#ECNUMBERS:1.1.1.49#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucose-6-phosphate dehydrogenase#ABBREVIATION:Zwf#</html:p>
                    <html:p>GENE ASSOCIATION: (b1852)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_6pgl_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_G6Pt6_2" name="Glucose-6-phosphate transport via phosphate antiport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_G6Pt6_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: g6p[e] + (2) pi[c] --&gt; g6p[c] + (2) pi[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3666#ABBREVIATION:uhpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, hexose phosphate:phosphate transporter#ABBREVIATION:UhpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3666)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g6p_e" />
                    <speciesReference species="M_pi_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_pi_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALCTD" name="galactarate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALCTD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.42</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : galct-D --&gt; 5dh4dglc + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3128#ABBREVIATION:garD#ECNUMBERS:4.2.1.42#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-galactarate dehydratase#ABBREVIATION:GarD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3128)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galct_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5dh4dglc_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALCTND" name="galactonate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALCTND</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.2.1.6</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : galctn-D --&gt; 2dh3dgal + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3692#ABBREVIATION:OBSOLETE (DgoA)#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-dehydro-3-deoxygalactonate 6-phosphate aldolase#ABBREVIATION:DgoA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3692)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galctn_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dh3dgal_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALCTNt2r" name="D-galactonate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GALCTNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: galctn-D[e] + h[e] &lt;==&gt; galctn-D[c] + h[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3691#ABBREVIATION:dgoT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS transporter, predicted D-galactonate transport#ABBREVIATION:DgoT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3691)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galctn_D_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galctn_D_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALCTt2r" name="D-galactarte transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GALCTt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: galct-D[e] + h[e] &lt;==&gt; galct-D[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3127#ABBREVIATION:garP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative, D-glucarate/D-galactarate transporter, MFS#ABBREVIATION:GarP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3127)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galct_D_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galct_D_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALKr" name="galactokinase">
                <notes>
                    <html:p>Abbreviation: R_GALKr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.6</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + gal &lt;==&gt; adp + gal1p + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - added reversible form of GALK</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0757#ABBREVIATION:galK#ECNUMBERS:2.7.1.6#</html:p>
                    <html:p>LOCUS:b2045#ABBREVIATION:wcaK#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:galactokinase#ABBREVIATION:GalK#</html:p>
                    <html:p>NAME:putative galactokinase#ABBREVIATION:WcaK#</html:p>
                    <html:p>GENE ASSOCIATION: (b0757) or (b2045)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gal_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gal1p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALS3" name="a-galactosidase (melibiose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALS3</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 3.2.1.22</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + melib --&gt; gal + glc-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4119#ABBREVIATION:melA#ECNUMBERS:3.2.1.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:alpha-galactosidase#ABBREVIATION:MelA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4119)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_melib_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gal_c" />
                    <speciesReference species="M_glc_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALTpts" name="Galactitol transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALTpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: galt[e] + pep[c] --&gt; galt1p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2092#ABBREVIATION:gatC#</html:p>
                    <html:p>LOCUS:b2093#ABBREVIATION:gatB#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2094#ABBREVIATION:gatA#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, galactitol IIA#ABBREVIATION:GatA#</html:p>
                    <html:p>NAME:PTS, galactitol IIB#ABBREVIATION:GatB#</html:p>
                    <html:p>NAME:PTS, galactitol IIC#ABBREVIATION:GatC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2092) and (b2094) and (b2416) and (b2093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galt_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galt1p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALU" name="UTP-glucose-1-phosphate uridylyltransferase">
                <notes>
                    <html:p>Abbreviation: R_GALU</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.9</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : g1p + h + utp &lt;==&gt; ppi + udpg</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1236#ABBREVIATION:galU#ECNUMBERS:2.7.7.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucose-1-phosphate uridylyltransferase#ABBREVIATION:GalUec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1236)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_utp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_udpg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALURt2r" name="D-galacturonate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GALURt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: galur[e] + h[e] &lt;==&gt; galur[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3093#ABBREVIATION:exuT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS hexuronate transport#ABBREVIATION:ExuT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galur_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_galur_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALabc" name="D-galactose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + gal[e] + h2o[c] --&gt; adp[c] + gal[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2148#ABBREVIATION:mglC#</html:p>
                    <html:p>LOCUS:b2149#ABBREVIATION:mglA#</html:p>
                    <html:p>LOCUS:b2150#ABBREVIATION:mglB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, galactose (atp)#ABBREVIATION:MglA#</html:p>
                    <html:p>NAME:ABC, galactose (periplasm)#ABBREVIATION:MglB#</html:p>
                    <html:p>NAME:ABC, galactose (membrane)#ABBREVIATION:MglC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2148) and (b2150) and (b2149)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gal_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gal_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GALt2" name="D-galactose transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GALt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: gal[e] + h[e] --&gt; gal[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2943#ABBREVIATION:galP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, galactose/glucose proton symporter#ABBREVIATION:GalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2943)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gal_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gal_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GAMpts" name="D-glucosamine transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GAMpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: gam[e] + pep[c] --&gt; gam6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1817#ABBREVIATION:manX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1818#ABBREVIATION:manY#</html:p>
                    <html:p>LOCUS:b1819#ABBREVIATION:manZ#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, mannose IIA#ABBREVIATION:ManX#</html:p>
                    <html:p>NAME:PTS, mannose IIC#ABBREVIATION:ManY#</html:p>
                    <html:p>NAME:PTS, mannose IID#ABBREVIATION:ManZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b1818) and (b1817) and (b1819)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gam_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gam6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GAPD" name="glyceraldehyde-3-phosphate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_GAPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.12</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : g3p + nad + pi &lt;==&gt; 13dpg + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1416#ABBREVIATION:gapC_2#ECNUMBERS:1.2.1.12#</html:p>
                    <html:p>LOCUS:b1417#ABBREVIATION:gapC_1#ECNUMBERS:1.2.1.12#</html:p>
                    <html:p>LOCUS:b1779#ABBREVIATION:gapA#ECNUMBERS:1.2.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glyceraldehyde-3-phosphate dehydrogenase A#ABBREVIATION:GapA#</html:p>
                    <html:p>NAME:glyceraldehyde-3-phosphate dehydrogenase C#ABBREVIATION:GapC#</html:p>
                    <html:p>GENE ASSOCIATION: (b1417 and b1416) or (b1779)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_13dpg_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GARFT" name="phosphoribosylglycinamide formyltransferase">
                <notes>
                    <html:p>Abbreviation: R_GARFT</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.1.2.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : 10fthf + gar &lt;==&gt; fgam + h + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2500#ABBREVIATION:purN#ECNUMBERS:2.1.2.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosylglycinamide formytransferase#ABBREVIATION:PurN#</html:p>
                    <html:p>GENE ASSOCIATION: (b2500)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_10fthf_c" />
                    <speciesReference species="M_gar_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fgam_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GART" name="GAR transformylase-T" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GART</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + for + gar --&gt; adp + fgam + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
JLR- EC is unassigned 2.1.2.-</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1849#ABBREVIATION:purT#ECNUMBERS:2.7.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosribosylglycinamide formyltransferase II#ABBREVIATION:PurT#</html:p>
                    <html:p>GENE ASSOCIATION: (b1849)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_gar_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fgam_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GCALDD" name="Glycolaldehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GCALDD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.21</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : gcald + h2o + nad --&gt; glyclt + (2) h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1415#ABBREVIATION:aldA#ECNUMBERS:1.2.1.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aldehyde dehydrogenase A#ABBREVIATION:AldA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1415)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gcald_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GDMANE" name="GDP-4-dehydro-6-deoxy-D-mannose epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GDMANE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gdpddman --&gt; gdpofuc</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (EC 5.1.3.-  ; reaction number R03400)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2052#ABBREVIATION:fcl#ECNUMBERS:5.1.3.-,-!-,1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GDP-fucose synthetase#ABBREVIATION:Fcl#</html:p>
                    <html:p>GENE ASSOCIATION: (b2052)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gdpddman_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdpofuc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GF6PTA" name="glutamine-fructose-6-phosphate transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GF6PTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.16</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : f6p + gln-L --&gt; gam6p + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3729#ABBREVIATION:glmS#ECNUMBERS:2.6.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glucosamine fructose-6-phosphate aminotransferase (isomerizing)#ABBREVIATION:GlmS#</html:p>
                    <html:p>GENE ASSOCIATION: (b3729)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_gln_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gam6p_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GHMT2" name="glycine hydroxymethyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GHMT2</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 2.1.2.1</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : ser-L + thf --&gt; gly + h2o + mlthf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- GHMT uses methf and it should be mlthf according to LIGAND and ExPASy</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2551#ABBREVIATION:glyA#ECNUMBERS:2.1.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine Hydroxymethyltransferase#ABBREVIATION:GlyA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ser_L_c" />
                    <speciesReference species="M_thf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gly_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mlthf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GK1" name="guanylate kinase (GMP:ATP)">
                <notes>
                    <html:p>Abbreviation: R_GK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.8</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + gmp &lt;==&gt; adp + gdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3648#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Guanylate kinase#ABBREVIATION:Gmkec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3648)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCDe" name="Glucose dehydrogenase (ubiquinone-8 as acceptor)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCDe</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: glc-D[e] + h2o[e] + q8[c] --&gt; glcn[e] + h[e] + q8h2[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR-Combination of 1.1.99.17 and 3.1.1.17</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0124#ABBREVIATION:gcd#ECNUMBERS:1.1.5.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glucose dehydrogenase (periplasmic)#ABBREVIATION:Gcd#</html:p>
                    <html:p>GENE ASSOCIATION: (b0124)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glc_D_e" />
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_e" />
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCNt2r" name="D-gluconate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLCNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glcn[e] + h[e] &lt;==&gt; glcn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3415#ABBREVIATION:gntT#</html:p>
                    <html:p>LOCUS:b4321#ABBREVIATION:gntP#</html:p>
                    <html:p>LOCUS:b4265#ABBREVIATION:idnT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Gluconate H symport #ABBREVIATION:GntT#</html:p>
                    <html:p>NAME:GntP family L-idonate transporter#ABBREVIATION:IdnT#</html:p>
                    <html:p>NAME:GntP family, glucontate transport via proton symport#ABBREVIATION:GntP#</html:p>
                    <html:p>GENE ASSOCIATION: (b4265) or (b3415) or (b4321)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCP" name="glycogen phosphorylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCP</html:p>
                    <html:p>Synonyms: _16</html:p>
                    <html:p>EC Number: 2.4.1.1</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : glycogen + pi --&gt; g1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>AMF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3417#ABBREVIATION:malP#ECNUMBERS:2.4.1.1#</html:p>
                    <html:p>LOCUS:b3428#ABBREVIATION:glgP#ECNUMBERS:2.4.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycogen phosphorylase#ABBREVIATION:GlgP#</html:p>
                    <html:p>NAME:maltodextrin phosphorylase#ABBREVIATION:MalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3428) or (b3417)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glycogen_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCRAL" name="_5-dehydro-4-deoxyglucarate aldolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCRAL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.20</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 5dh4dglc --&gt; 2h3oppan + pyr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3126#ABBREVIATION:garL#ECNUMBERS:4.1.2.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:alpha-dehydro-beta-deoxy-D-glucarate aldolase#ABBREVIATION:GarL#</html:p>
                    <html:p>GENE ASSOCIATION: (b3126)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5dh4dglc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2h3oppan_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCRD" name="glucarate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCRD</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.2.1.40</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glcr --&gt; 5dh4dglc + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2787#ABBREVIATION:gudD#ECNUMBERS:4.2.1.40#</html:p>
                    <html:p>LOCUS:b2788#ABBREVIATION:gudX#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-glucarate dehydratase I#ABBREVIATION:GudD#</html:p>
                    <html:p>NAME:putative D-glucarate dehydratase 2#ABBREVIATION:YgcY#</html:p>
                    <html:p>GENE ASSOCIATION: (b2787) or (b2788)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5dh4dglc_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCRt2r" name="D-glucarate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLCRt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: glcr[e] + h[e] &lt;==&gt; glcr[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2789#ABBREVIATION:gudP#</html:p>
                    <html:p>LOCUS:b3127#ABBREVIATION:garP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative, D-glucarate/D-galactarate transporter, MFS#ABBREVIATION:GarP#</html:p>
                    <html:p>NAME:putative D-glucarate permease, MFS#ABBREVIATION:GudP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3127) or (b2789)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcr_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcr_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCS1" name="glycogen synthase (ADPGlc)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.21</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : adpglc --&gt; adp + glycogen + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3429#ABBREVIATION:glgA#ECNUMBERS:2.4.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycogen synthase#ABBREVIATION:GlgA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3429)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adpglc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glycogen_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCURt2r" name="D-glucuronate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLCURt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glcur[e] + h[e] &lt;==&gt; glcur[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3093#ABBREVIATION:exuT#</html:p>
                    <html:p>LOCUS:b3909#ABBREVIATION:kdgT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS hexuronate transport#ABBREVIATION:ExuT#</html:p>
                    <html:p>NAME:_2-keto-3-deoxy-D-gluconate transporter#ABBREVIATION:KdgT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3909) or (b3093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcur_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glcur_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCpts" name="D-glucose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glc-D[e] + pep[c] --&gt; g6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1101#ABBREVIATION:ptsG#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1817#ABBREVIATION:manX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1818#ABBREVIATION:manY#</html:p>
                    <html:p>LOCUS:b1819#ABBREVIATION:manZ#</html:p>
                    <html:p>LOCUS:b1621#ABBREVIATION:malX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2417#ABBREVIATION:crr#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, Glucose/Trehalose/Maltose IIA#ABBREVIATION:Crr#</html:p>
                    <html:p>NAME:PTS, glucose IIBC#ABBREVIATION:PtsG#</html:p>
                    <html:p>NAME:PTS, mannose IIA#ABBREVIATION:ManX#</html:p>
                    <html:p>NAME:PTS, mannose IIC#ABBREVIATION:ManY#</html:p>
                    <html:p>NAME:PTS, mannose IID#ABBREVIATION:ManZ#</html:p>
                    <html:p>NAME:PTS, Maltose IIC#ABBREVIATION:MalX#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2417) and (b2416) and (b1101) or (b2415) and (b2416) and (b1818) and (b1817) and (b1819) or (b1621) and (b2415) and (b2417) and (b2416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glc_D_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLCt2" name="D-glucose transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLCt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glc-D[e] + h[e] --&gt; glc-D[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2943#ABBREVIATION:galP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, galactose/glucose proton symporter#ABBREVIATION:GalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2943)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glc_D_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLGC" name="glucose-1-phosphate adenylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLGC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.27</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : atp + g1p + h --&gt; adpglc + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3430#ABBREVIATION:glgC#ECNUMBERS:2.7.7.27#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucose-1-phosphate adenyltransferase#ABBREVIATION:GlgC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3430)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adpglc_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLNS" name="glutamine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLNS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.1.2</html:p>
                    <html:p>SUBSYSTEM: Glutamate metabolism</html:p>
                    <html:p>Equation: [c] : atp + glu-L + nh4 --&gt; adp + gln-L + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1297#ABBREVIATION:puuA#</html:p>
                    <html:p>LOCUS:b3870#ABBREVIATION:glnA#ECNUMBERS:6.3.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamine synthetase#ABBREVIATION:GlnA#</html:p>
                    <html:p>NAME:putative glutamine synthetase#ABBREVIATION:YcjK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3870) or (b1297)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLNabc" name="L-glutamine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLNabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + gln-L[e] + h2o[c] --&gt; adp[c] + gln-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0809#ABBREVIATION:glnQ#</html:p>
                    <html:p>LOCUS:b0810#ABBREVIATION:glnP#</html:p>
                    <html:p>LOCUS:b0811#ABBREVIATION:glnH#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, glutamine (periplasm)#ABBREVIATION:GlnHec#</html:p>
                    <html:p>NAME:ABC, glutamine (membrane)#ABBREVIATION:GlnPec#</html:p>
                    <html:p>NAME:ABC, glutamine (atp)#ABBREVIATION:GlnQec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0810) and (b0811) and (b0809)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gln_L_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLTPD" name="Galactitol-1-phosphate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_GLTPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : galt1p + nad &lt;==&gt; h + nadh + tag6p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- EC 1.1.1.251 generates the L-form of tagatose-6-phosphate, used this reaction because EcoCyc indicates that it generates the D-form</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2091#ABBREVIATION:gatD#ECNUMBERS:1.1.1.251#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:galactitol-1-phosphate dehydrogenase#ABBREVIATION:GatD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2091)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galt1p_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_tag6p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLU5K" name="glutamate 5-kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLU5K</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.11</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : atp + glu-L --&gt; adp + glu5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0242#ABBREVIATION:proB#ECNUMBERS:2.7.2.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:gamma-glutamate kinase#ABBREVIATION:ProB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0242)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glu5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUABUTt7" name="_4-aminobutyrate/glutamate antiport">
                <notes>
                    <html:p>Abbreviation: R_GLUABUTt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: _4abut[c] + glu-L[e] &lt;==&gt; 4abut[e] + glu-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1492#ABBREVIATION:gadC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative glutamate:gamma-aminobutyrate antiporter, APC#ABBREVIATION:XasA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1492)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4abut_c" />
                    <speciesReference species="M_glu_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abut_e" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUCYS" name="gamma-glutamylcysteine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUCYS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.2</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + cys-L + glu-L --&gt; adp + glucys + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2688#ABBREVIATION:gshA#ECNUMBERS:6.3.2.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamate cysteine ligase#ABBREVIATION:GshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2688)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glucys_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUDC" name="Glutamate Decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.15</html:p>
                    <html:p>SUBSYSTEM: Glutamate metabolism</html:p>
                    <html:p>Equation: [c] : glu-L + h --&gt; 4abut + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added h to balance</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1493#ABBREVIATION:gadB#ECNUMBERS:4.1.1.15#</html:p>
                    <html:p>LOCUS:b3517#ABBREVIATION:gadA#ECNUMBERS:4.1.1.15#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glutamate decarboxylase A#ABBREVIATION:GadA#</html:p>
                    <html:p>NAME:Glutamate decarboxylase B#ABBREVIATION:GadB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3517) or (b1493)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abut_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUDy" name="glutamate dehydrogenase (NADP)">
                <notes>
                    <html:p>Abbreviation: R_GLUDy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.1.4</html:p>
                    <html:p>SUBSYSTEM: Glutamate metabolism</html:p>
                    <html:p>Equation: [c] : glu-L + h2o + nadp &lt;==&gt; akg + h + nadph + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1761#ABBREVIATION:gdhA#ECNUMBERS:1.4.1.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamate dehydrogenase#ABBREVIATION:GdhA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1761)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUN" name="glutaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.2</html:p>
                    <html:p>SUBSYSTEM: Glutamate metabolism</html:p>
                    <html:p>Equation: [c] : gln-L + h2o --&gt; glu-L + nh4</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0485#ABBREVIATION:ybaS#</html:p>
                    <html:p>LOCUS:b1812#ABBREVIATION:pabB#ECNUMBERS:6.3.5.8#</html:p>
                    <html:p>LOCUS:b1524#ABBREVIATION:yneH#</html:p>
                    <html:p>LOCUS:b2957#ABBREVIATION:ansB#ECNUMBERS:3.5.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-asparaginase II#ABBREVIATION:AnsB#</html:p>
                    <html:p>NAME:putative glutaminase#ABBREVIATION:YneH#</html:p>
                    <html:p>NAME:putative glutaminase#ABBREVIATION:YbaS#</html:p>
                    <html:p>NAME:p-aminobenzoate synthetase, component I#ABBREVIATION:PabBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2957) or (b0485) or (b1812) or (b1524)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUPRT" name="glutamine phosphoribosyldiphosphate amidotransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.14</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : gln-L + h2o + prpp --&gt; glu-L + ppi + pram</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2312#ABBREVIATION:purF#ECNUMBERS:2.4.2.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Amidophosphoribosyltransferase#ABBREVIATION:PurF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2312)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_pram_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUR" name="glutamate racemase">
                <notes>
                    <html:p>Abbreviation: R_GLUR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.1.3</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : glu-D &lt;==&gt; glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3967#ABBREVIATION:murI#ECNUMBERS:5.1.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glutamate racemase#ABBREVIATION:MurI#</html:p>
                    <html:p>GENE ASSOCIATION: (b3967)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUSy" name="glutamate synthase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUSy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.1.13</html:p>
                    <html:p>SUBSYSTEM: Glutamate metabolism</html:p>
                    <html:p>Equation: [c] : akg + gln-L + h + nadph --&gt; (2) glu-L + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3212#ABBREVIATION:gltB#ECNUMBERS:1.4.1.13#</html:p>
                    <html:p>LOCUS:b3213#ABBREVIATION:gltD#ECNUMBERS:1.4.1.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glutamate synthase#ABBREVIATION:GltB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3212 and b3213)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" stoichiometry="2" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUTRR" name="glutamyl-tRNA reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUTRR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : glutrna + h + nadph --&gt; glu1sa + nadp + trnaglu</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1210#ABBREVIATION:hemA#ECNUMBERS:1.2.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamyl-tRNA reductase#ABBREVIATION:HemA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1210)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glutrna_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu1sa_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_trnaglu_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUTRS" name="Glutamyl-tRNA synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUTRS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.1.1.17</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + glu-L + trnaglu --&gt; amp + glutrna + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2400#ABBREVIATION:gltX#ECNUMBERS:6.1.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamyl-tRNA synthetase#ABBREVIATION:GltX#</html:p>
                    <html:p>GENE ASSOCIATION: (b2400)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_trnaglu_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_glutrna_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUabc" name="L-glutamate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + glu-L[e] + h2o[c] --&gt; adp[c] + glu-L[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0652#ABBREVIATION:gltL#</html:p>
                    <html:p>LOCUS:b0653#ABBREVIATION:gltK#</html:p>
                    <html:p>LOCUS:b0654#ABBREVIATION:gltJ#</html:p>
                    <html:p>LOCUS:b0655#ABBREVIATION:gltI#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (periplasm)#ABBREVIATION:GltI#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (membrane)#ABBREVIATION:GltJ#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (membrane)#ABBREVIATION:GltK#</html:p>
                    <html:p>NAME:ABC, glutamate/aspartate transport (atp)#ABBREVIATION:GltL#</html:p>
                    <html:p>GENE ASSOCIATION: (b0653) and (b0654) and (b0655) and (b0652)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glu_L_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUt2r" name="L-glutamate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLUt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glu-L[e] + h[e] &lt;==&gt; glu-L[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4077#ABBREVIATION:gltP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP#</html:p>
                    <html:p>GENE ASSOCIATION: (b4077)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLUt4" name="Na+/glutamate symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLUt4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glu-L[e] + na1[e] --&gt; glu-L[c] + na1[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3653#ABBREVIATION:gltS#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutamate permease#ABBREVIATION:GltS#</html:p>
                    <html:p>GENE ASSOCIATION: (b3653)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_e" />
                    <speciesReference species="M_na1_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_na1_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLXCL" name="glyoxalate carboligase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLXCL</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 4.1.1.47</html:p>
                    <html:p>SUBSYSTEM: Glyoxylate Metabolism</html:p>
                    <html:p>Equation: [c] : (2) glx + h --&gt; 2h3oppan + co2</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0507#ABBREVIATION:gcl#ECNUMBERS:4.1.1.47#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glyoxylate carboligase#ABBREVIATION:Gcl#</html:p>
                    <html:p>GENE ASSOCIATION: (b0507)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glx_c" stoichiometry="2" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2h3oppan_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYALDt" name="Glyceraldehyde facilitated diffusion">
                <notes>
                    <html:p>Abbreviation: R_GLYALDt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glyald[e] &lt;==&gt; glyald[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3927#ABBREVIATION:glpF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3927)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyald_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyald_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYATi" name="glycine C-acetyltransferase (irreversible)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYATi</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.3.1.29</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : 2aobut + coa --&gt; accoa + gly</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - added irreversible form of GLYAT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3617#ABBREVIATION:kbl#ECNUMBERS:2.3.1.29#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-amino-3-ketobutyrate CoA ligase#ABBREVIATION:Kbl#</html:p>
                    <html:p>GENE ASSOCIATION: (b3617)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2aobut_c" />
                    <speciesReference species="M_coa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_gly_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYBabc" name="Glycine betaine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYBabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: atp[c] + glyb[e] + h2o[c] --&gt; adp[c] + glyb[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2128#ABBREVIATION:yehW#</html:p>
                    <html:p>LOCUS:b2129#ABBREVIATION:yehX#</html:p>
                    <html:p>LOCUS:b2130#ABBREVIATION:yehY#</html:p>
                    <html:p>LOCUS:b2131#ABBREVIATION:yehZ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (membrane)#ABBREVIATION:YehW#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (atp_bind)#ABBREVIATION:YehX#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (membrane)#ABBREVIATION:YehY#</html:p>
                    <html:p>NAME:putative ABC choline/betaine transporter (peri_bind)#ABBREVIATION:YehZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2130) and (b2128) and (b2131) and (b2129)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glyb_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glyb_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYBt2r" name="Glycine betaine transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLYBt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: glyb[e] + h[e] &lt;==&gt; glyb[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1801#ABBREVIATION:yeaV#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative betaine/choline/glycine transporter, BCCT#ABBREVIATION:YeaV#</html:p>
                    <html:p>GENE ASSOCIATION: (b1801)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyb_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyb_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYC3Pabc" name="sn-Glycerol 3-phosphate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYC3Pabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + glyc3p[e] + h2o[c] --&gt; adp[c] + glyc3p[c] + h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3450#ABBREVIATION:ugpC#</html:p>
                    <html:p>LOCUS:b3451#ABBREVIATION:ugpE#</html:p>
                    <html:p>LOCUS:b3452#ABBREVIATION:ugpA#</html:p>
                    <html:p>LOCUS:b3453#ABBREVIATION:ugpB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC transporter, glycerol-3-phosphate (membrane)#ABBREVIATION:UgpA#</html:p>
                    <html:p>NAME:ABC transporter, glycerol-3-phosphate (membrane)#ABBREVIATION:UgpE#</html:p>
                    <html:p>NAME:ABC transporter, glycerol-3-phosphate (peri_bind)#ABBREVIATION:UgpB#</html:p>
                    <html:p>NAME:ABC transporter, glycerol-3-phosphate (atp_bind)#ABBREVIATION:UgpC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3451) and (b3453) and (b3452) and (b3450)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glyc3p_e" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYC3Pt6" name="Glycerol-3-phosphate : phosphate antiporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYC3Pt6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glyc3p[e] + pi[c] --&gt; glyc3p[c] + pi[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2240#ABBREVIATION:glpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, glycerol-3-phosphate phosphate antiporter#ABBREVIATION:GlpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b2240)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_e" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_pi_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCDx" name="Glycerol dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCDx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.6</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glyc + nad --&gt; dha + h + nadh</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3945#ABBREVIATION:gldA#ECNUMBERS:1.1.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerol dehydrogenase#ABBREVIATION:GldA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3945)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dha_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCK" name="glycerate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCK</html:p>
                    <html:p>Synonyms: _7</html:p>
                    <html:p>EC Number: 2.7.1.31</html:p>
                    <html:p>SUBSYSTEM: Glyoxylate Metabolism</html:p>
                    <html:p>Equation: [c] : atp + glyc-R --&gt; 3pg + adp + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0514#ABBREVIATION:glxK#ECNUMBERS:2.7.1.31#</html:p>
                    <html:p>LOCUS:b3124#ABBREVIATION:garK#ECNUMBERS:2.7.1.31#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerate Kinase II#ABBREVIATION:GlxK#</html:p>
                    <html:p>NAME:glycerate kinase I#ABBREVIATION:GarK#</html:p>
                    <html:p>GENE ASSOCIATION: (b0514) or (b3124)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glyc_R_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3pg_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCL" name="Glycine Cleavage System" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : gly + nad + thf --&gt; co2 + mlthf + nadh + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - Ecoli</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0116#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4#</html:p>
                    <html:p>LOCUS:b2903#ABBREVIATION:gcvP#ECNUMBERS:1.4.4.2#</html:p>
                    <html:p>LOCUS:b2904#ABBREVIATION:gcvH#</html:p>
                    <html:p>LOCUS:b2905#ABBREVIATION:gcvT#ECNUMBERS:2.1.2.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA#</html:p>
                    <html:p>NAME:glycine cleavage complex, H#ABBREVIATION:GcvH#</html:p>
                    <html:p>NAME:Glycine cleavage complex, P#ABBREVIATION:GcvP#</html:p>
                    <html:p>NAME:Glycine cleavage complex, T#ABBREVIATION:GcvT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0116) and (b2903) and (b2905) and (b2904)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gly_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_thf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_mlthf_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCLTDx" name="Glycolate dehydrogenase (NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCLTDx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Glyoxylate Metabolism</html:p>
                    <html:p>Equation: [c] : glx + h + nadh --&gt; glyclt + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1033#ABBREVIATION:ycdW#ECNUMBERS:1.1.1.79#</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>NAME:_2-ketoacid reductase#ABBREVIATION:YcdW#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553) or (b1033)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCLTDy" name="Glycolate dehydrogenase (NADP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCLTDy</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.1.1.26</html:p>
                    <html:p>SUBSYSTEM: Glyoxylate Metabolism</html:p>
                    <html:p>Equation: [c] : glx + h + nadph --&gt; glyclt + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1033#ABBREVIATION:ycdW#ECNUMBERS:1.1.1.79#</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>NAME:_2-ketoacid reductase#ABBREVIATION:YcdW#</html:p>
                    <html:p>GENE ASSOCIATION: (b3553) or (b1033)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCLTt2r" name="glycolate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_GLYCLTt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glyclt[e] + h[e] &lt;==&gt; glyclt[c] + h[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2975#ABBREVIATION:yghK#</html:p>
                    <html:p>LOCUS:b3603#ABBREVIATION:lldP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:LctP transporter, L-lactate/D-lactate/Glycolate H symporter#ABBREVIATION:LldP#</html:p>
                    <html:p>NAME:putative L-lactate permease, LctP family#ABBREVIATION:GlcA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2975) or (b3603)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyclt_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCTO2" name="Glycolate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCTO2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glyclt + q8 --&gt; glx + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- not sure about electron acceptor</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2978#ABBREVIATION:OBSOLETE (glcF)#</html:p>
                    <html:p>LOCUS:b2979#ABBREVIATION:glcD#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycolate oxidase#ABBREVIATION:GlcDF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2979 and b2978)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCTO3" name="Glycolate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCTO3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glyclt + mqn8 --&gt; glx + mql8</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2978#ABBREVIATION:OBSOLETE (glcF)#</html:p>
                    <html:p>LOCUS:b2979#ABBREVIATION:glcD#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycolate oxidase#ABBREVIATION:GlcDF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2979 and b2978)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_mql8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCTO4" name="Glycolate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYCTO4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dmmq8 + glyclt --&gt; 2dmmql8 + glx</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2978#ABBREVIATION:OBSOLETE (glcF)#</html:p>
                    <html:p>LOCUS:b2979#ABBREVIATION:glcD#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycolate oxidase#ABBREVIATION:GlcDF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2979 and b2978)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_glyclt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_glx_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYCt" name="glycerol transport via channel">
                <notes>
                    <html:p>Abbreviation: R_GLYCt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: glyc[c] &lt;==&gt; glyc[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3927#ABBREVIATION:glpF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3927)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYK" name="glycerol kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.30</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + glyc --&gt; adp + glyc3p + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3926#ABBREVIATION:glpK#ECNUMBERS:2.7.1.30#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glycerol kinase#ABBREVIATION:GlpK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3926)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glyc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYOX" name="hydroxyacylglutathione hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GLYOX</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 3.1.2.6</html:p>
                    <html:p>SUBSYSTEM: Methylglyoxal Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + lgt-S --&gt; gthrd + h + lac-D</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0212#ABBREVIATION:gloB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydroxyacylglutathione hydrolase#ABBREVIATION:GloB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0212)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_lgt_S_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gthrd_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lac_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GLYt2r" name="glycine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_GLYt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: gly[e] + h[e] &lt;==&gt; gly[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0007#ABBREVIATION:yaaJ#</html:p>
                    <html:p>LOCUS:b1801#ABBREVIATION:yeaV#</html:p>
                    <html:p>LOCUS:b4208#ABBREVIATION:cycA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, D-ala/D-ser/glycine transport#ABBREVIATION:CycAec#</html:p>
                    <html:p>NAME:putative betaine/choline/glycine transporter, BCCT#ABBREVIATION:YeaV#</html:p>
                    <html:p>NAME:putative alanine/glycine transporter, AGCS#ABBREVIATION:YaaJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b1801) or (b4208) or (b0007)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gly_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gly_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMAND" name="GDP-D-mannose dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMAND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.47</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gdpmann --&gt; gdpddman + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2053#ABBREVIATION:gmd#ECNUMBERS:4.2.1.47#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GDP-D-mannose dehydratase#ABBREVIATION:Gmd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2053)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gdpmann_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdpddman_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMHEPAT" name="D-glycero-D-manno-hepose 1-phosphate adenyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMHEPAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + gmhep1p + h --&gt; adphep-DD + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR Kegg RXN R05644</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3052#ABBREVIATION:rfaE#ECNUMBERS:2.7.1.-,-!-,2.7.7.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ADP-L-glycero-D-manno-heptose synthase#ABBREVIATION:RfaEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3052)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gmhep1p_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adphep_DD_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMHEPK" name="D-glycero-D-manno-heptose 7-phosphate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMHEPK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + gmhep7p --&gt; adp + gmhep17bp + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- Kegg RXN R05646</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3052#ABBREVIATION:rfaE#ECNUMBERS:2.7.1.-,-!-,2.7.7.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ADP-L-glycero-D-manno-heptose synthase#ABBREVIATION:RfaEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3052)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gmhep7p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gmhep17bp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMHEPPA" name="D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMHEPPA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gmhep17bp + h2o --&gt; gmhep1p + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR Kegg RXN R05647</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0200#ABBREVIATION:gmhB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D,D-heptose 1,7-bisphosphate phosphatase#ABBREVIATION:GmhB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0200)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gmhep17bp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gmhep1p_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMPR" name="GMP reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMPR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.7.1.7</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : gmp + (2) h + nadph --&gt; imp + nadp + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC- changed from 1.7.1.7</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0104#ABBREVIATION:guaC#ECNUMBERS:1.7.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GMP reductase#ABBREVIATION:GuaC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0104)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_imp_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GMPS2" name="GMP synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GMPS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.5.2</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + gln-L + h2o + xmp --&gt; amp + glu-L + gmp + (2) h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2507#ABBREVIATION:guaA#ECNUMBERS:6.3.5.2,-!-,6.3.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GMP synthase#ABBREVIATION:GuaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2507)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_xmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GND" name="phosphogluconate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.44</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : 6pgc + nadp --&gt; co2 + nadph + ru5p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP
Note no proton generation by the the reaction</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2029#ABBREVIATION:gnd#ECNUMBERS:1.1.1.44#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_6-phosphogluconate dehydrogenase, decarboxylating#ABBREVIATION:Gnd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2029)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_6pgc_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_ru5p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GNK" name="gluconokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GNK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.12</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + glcn --&gt; 6pgc + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3437#ABBREVIATION:gntK#ECNUMBERS:2.7.1.12#</html:p>
                    <html:p>LOCUS:b4268#ABBREVIATION:idnK#ECNUMBERS:2.7.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-gluconate kinase#ABBREVIATION:IdnK#</html:p>
                    <html:p>NAME:D-gluconate kinase II#ABBREVIATION:GntK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4268) or (b3437)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glcn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_6pgc_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GOFUCR" name="GDP-4-oxo-L-fucose reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GOFUCR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gdpofuc + h + nadph --&gt; gdpfuc + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (EC 1.-.-.-; Reaction number R01950)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2052#ABBREVIATION:fcl#ECNUMBERS:5.1.3.-,-!-,1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GDP-fucose synthetase#ABBREVIATION:Fcl#</html:p>
                    <html:p>GENE ASSOCIATION: (b2052)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gdpofuc_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdpfuc_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GP4GH" name="Gp4G hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GP4GH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gp4g + h2o --&gt; (2) gdp + (2) h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0049#ABBREVIATION:apaH#ECNUMBERS:3.6.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:diadenosine tetraphosphatase#ABBREVIATION:ApaH#</html:p>
                    <html:p>GENE ASSOCIATION: (b0049)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gp4g_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdp_c" stoichiometry="2" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GPDDA1" name="Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GPDDA1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.4.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3pc + h2o --&gt; chol + glyc3p + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2239#ABBREVIATION:glpQ#ECNUMBERS:3.1.4.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerophosphodiester phosphodiesterase#ABBREVIATION:GlpQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3pc_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_chol_c" />
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GPDDA2" name="Glycerophosphodiester phosphodiesterase (Glycerophosphoethanolamine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GPDDA2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.4.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3pe + h2o --&gt; etha + glyc3p + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2239#ABBREVIATION:glpQ#ECNUMBERS:3.1.4.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerophosphodiester phosphodiesterase#ABBREVIATION:GlpQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3pe_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_etha_c" />
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GPDDA3" name="Glycerophosphodiester phosphodiesterase (Glycerophosphoserine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GPDDA3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.4.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3ps + h2o --&gt; glyc3p + h + ser-L</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2239#ABBREVIATION:glpQ#ECNUMBERS:3.1.4.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerophosphodiester phosphodiesterase#ABBREVIATION:GlpQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3ps_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GPDDA4" name="Glycerophosphodiester phosphodiesterase (Glycerophosphoglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GPDDA4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.4.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3pg + h2o --&gt; glyc + glyc3p + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2239#ABBREVIATION:glpQ#ECNUMBERS:3.1.4.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerophosphodiester phosphodiesterase#ABBREVIATION:GlpQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3pg_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_c" />
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GPDDA5" name="Glycerophosphodiester phosphodiesterase (Glycerophosphoinositol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GPDDA5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.4.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : g3pi + h2o --&gt; glyc3p + h + inost</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2239#ABBREVIATION:glpQ#ECNUMBERS:3.1.4.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glycerophosphodiester phosphodiesterase#ABBREVIATION:GlpQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3pi_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_inost_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GRTT" name="geranyltranstransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GRTT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.10</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : grdp + ipdp --&gt; frdp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0421#ABBREVIATION:ispA#ECNUMBERS:2.5.1.10,-!-,2.5.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Geranyltransferase#ABBREVIATION:IspA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0421)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_grdp_c" />
                    <speciesReference species="M_ipdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_frdp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GSNK" name="guanosine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GSNK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + gsn --&gt; adp + gmp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0477#ABBREVIATION:gsk#ECNUMBERS:2.7.1.73#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Insosine-guanosine kinase#ABBREVIATION:Gsk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0477)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gsn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GSNt2" name="guanosine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GSNt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: gsn[e] + h[e] --&gt; gsn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2964#ABBREVIATION:nupG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, nucleoside transport (G-system)#ABBREVIATION:NupG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2964)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gsn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gsn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GSPMDA" name="Glutathionylspermidine amidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GSPMDA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.78</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : gtspmd + h2o --&gt; gthrd + spmd</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2988#ABBREVIATION:gss#ECNUMBERS:3.5.1.78,-!-,6.3.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutathionylspermidine synthetase and amidase#ABBREVIATION:Gsp#</html:p>
                    <html:p>GENE ASSOCIATION: (b2988)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtspmd_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gthrd_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GSPMDS" name="Glutathionylspermidine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GSPMDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.1.8</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : atp + gthrd + spmd --&gt; adp + gtspmd + h + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2988#ABBREVIATION:gss#ECNUMBERS:3.5.1.78,-!-,6.3.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glutathionylspermidine synthetase and amidase#ABBREVIATION:Gsp#</html:p>
                    <html:p>GENE ASSOCIATION: (b2988)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gthrd_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gtspmd_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GTHOr" name="glutathione oxidoreductase">
                <notes>
                    <html:p>Abbreviation: R_GTHOr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.8.1.7</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : gthox + h + nadph &lt;==&gt; (2) gthrd + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3500#ABBREVIATION:gor#ECNUMBERS:1.8.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)#ABBREVIATION:GAPOR#</html:p>
                    <html:p>GENE ASSOCIATION: (b3500)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gthox_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gthrd_c" stoichiometry="2" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GTHS" name="glutathione synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GTHS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + glucys + gly --&gt; adp + gthrd + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2947#ABBREVIATION:gshB#ECNUMBERS:6.3.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glutathione synthase#ABBREVIATION:GshB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2947)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glucys_c" />
                    <speciesReference species="M_gly_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gthrd_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GTPCI" name="GTP cyclohydrolase I" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GTPCI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.16</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : gtp + h2o --&gt; ahdt + for</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2153#ABBREVIATION:folE#ECNUMBERS:3.5.4.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GTP cyclohydrolase I#ABBREVIATION:FolE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2153)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ahdt_c" />
                    <speciesReference species="M_for_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GTPCII2" name="GTP cyclohydrolase II (25drapp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GTPCII2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : gtp + (3) h2o --&gt; 25drapp + for + (2) h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1277#ABBREVIATION:ribA#ECNUMBERS:3.5.4.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GTP cyclohydrolase II#ABBREVIATION:RibA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1277)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_25drapp_c" />
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUAD" name="guanine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GUAD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.3</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gua + h + h2o --&gt; nh4 + xan</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2883#ABBREVIATION:guaD#ECNUMBERS:3.5.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:guanine deaminase#ABBREVIATION:YgfP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2883)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gua_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_xan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUAPRT" name="guanine phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GUAPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.8</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gua + prpp --&gt; gmp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Guanine and 6-mercaptopurine can replace hypoxanthine

EC added (2.4.2.7 makes the same reaction) IT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0125#ABBREVIATION:hpt#ECNUMBERS:2.4.2.8#</html:p>
                    <html:p>LOCUS:b0238#ABBREVIATION:gpt#ECNUMBERS:2.4.2.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Xanthine guanine phosphoribosyl transferase#ABBREVIATION:Gpt#</html:p>
                    <html:p>NAME:Hypoxanthine phosphoribosyltransferase#ABBREVIATION:Hpt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0238) or (b0125)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gua_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUAt" name="Guanine transport">
                <notes>
                    <html:p>Abbreviation: R_GUAt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: gua[e] &lt;==&gt; gua[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gua_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gua_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUAt2" name="guanine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_GUAt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: gua[e] + h[e] --&gt; gua[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3654#ABBREVIATION:yicE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative puring/xanthine transport, NCS2#ABBREVIATION:YicE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3654)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gua_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gua_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUI1" name="glucuronate isomerase (D-glucuronate)">
                <notes>
                    <html:p>Abbreviation: R_GUI1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.12</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : glcur &lt;==&gt; fruur</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3092#ABBREVIATION:uxaC#ECNUMBERS:5.3.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uronate isomerase#ABBREVIATION:UxaC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3092)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glcur_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fruur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_GUI2" name="glucuronate isomerase (D-galacturonate)">
                <notes>
                    <html:p>Abbreviation: R_GUI2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.12</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : galur &lt;==&gt; tagur</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3092#ABBREVIATION:uxaC#ECNUMBERS:5.3.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uronate isomerase#ABBREVIATION:UxaC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3092)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_galur_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_tagur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_H2Ot" name="H2O transport via diffusion">
                <notes>
                    <html:p>Abbreviation: R_H2Ot</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h2o[e] &lt;==&gt; h2o[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>renamed from H20t5 to H2Ot
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HBZOPT" name="Hydroxybenzoate octaprenyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HBZOPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4hbz + octdp --&gt; 3ophb + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
JLR - EC 2.5.1.-</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4040#ABBREVIATION:ubiA#ECNUMBERS:2.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_4-hydroxybenzoate octaprenyltransferase#ABBREVIATION:UbiA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4040)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4hbz_c" />
                    <speciesReference species="M_octdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3ophb_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HCINNMt2r" name="_3-hydroxycinnamic acid transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_HCINNMt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: _3hcinnm[e] + h[e] &lt;==&gt; 3hcinnm[c] + h[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0353#ABBREVIATION:mhpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative 3-(3-hydroxyphenyl)propionate and 3-hydroxycinnimate transporter, MFS#ABBREVIATION:MhpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0353)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hcinnm_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3hcinnm_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HCO3E" name="HCO3 equilibration reaction">
                <notes>
                    <html:p>Abbreviation: R_HCO3E</html:p>
                    <html:p>Synonyms: _7</html:p>
                    <html:p>EC Number: 4.2.1.1</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : co2 + h2o &lt;==&gt; h + hco3</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0126#ABBREVIATION:can#ECNUMBERS:4.2.1.1#</html:p>
                    <html:p>LOCUS:b0339#ABBREVIATION:cynT#ECNUMBERS:4.2.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:carbonic anhydrase#ABBREVIATION:CynT#</html:p>
                    <html:p>NAME:putative carbonic anhydrase#ABBREVIATION:YadF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0339) or (b0126)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hco3_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HDCAt2" name="Hexadecanoate transport via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HDCAt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + hdca[e] --&gt; h[c] + hdca[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2344#ABBREVIATION:fadL#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:long chain fatty acid transporter#ABBREVIATION:FadL#</html:p>
                    <html:p>GENE ASSOCIATION: (b2344)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_hdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HEMEOS" name="Heme O synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HEMEOS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : frdp + h2o + pheme --&gt; hemeO + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0428#ABBREVIATION:cyoE#ECNUMBERS:2.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Heme O synthase#ABBREVIATION:CyoE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0428)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_frdp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pheme_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hemeO_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HETZK" name="hydroxyethylthiazole kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HETZK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.50</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4mhetz + atp --&gt; 4mpetz + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2104#ABBREVIATION:thiM#ECNUMBERS:2.7.1.50#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydroxyethylthiazole kinase#ABBREVIATION:ThiMec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2104)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4mhetz_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4mpetz_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HEX1" name="hexokinase (D-glucose:ATP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HEX1</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.7.1.1</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : atp + glc-D --&gt; adp + g6p + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>D-Glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. Reaction also associated with EC 2.7.1.2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2388#ABBREVIATION:glk#ECNUMBERS:2.7.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Glucokinase#ABBREVIATION:Glk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2388)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glc_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HISTD" name="histidinol dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HISTD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.23</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + histd + (2) nad --&gt; (3) h + his-L + (2) nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2020#ABBREVIATION:hisD#ECNUMBERS:1.1.1.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Histidinol dehydrogenase#ABBREVIATION:HisD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2020)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_histd_c" />
                    <speciesReference species="M_nad_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_his_L_c" />
                    <speciesReference species="M_nadh_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HISTP" name="histidinol-phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HISTP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.15</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + hisp --&gt; histd + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2022#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2022)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_hisp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_histd_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HISabc" name="L-histidine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HISabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + his-L[e] --&gt; adp[c] + h[c] + his-L[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2306#ABBREVIATION:hisP#</html:p>
                    <html:p>LOCUS:b2307#ABBREVIATION:hisM#</html:p>
                    <html:p>LOCUS:b2308#ABBREVIATION:hisQ#</html:p>
                    <html:p>LOCUS:b2309#ABBREVIATION:hisJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, his and lys/arg/orn (membrane)#ABBREVIATION:HisM#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (atp)#ABBREVIATION:HisP#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (membrane)#ABBREVIATION:HisQ#</html:p>
                    <html:p>NAME:ABC, histidine (periplasm)#ABBREVIATION:HisJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2309) and (b2308) and (b2307) and (b2306)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_his_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_his_L_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HISt2r" name="L-histidine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_HISt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + his-L[e] &lt;==&gt; h[c] + his-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0112#ABBREVIATION:aroP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, aromatic AA proton symporter#ABBREVIATION:AroP#</html:p>
                    <html:p>GENE ASSOCIATION: (b0112)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_his_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_his_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HKNDDH" name="_2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HKNDDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + hkndd --&gt; (2) h + op4en + succ</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- Kegg reaction 02603</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0349#ABBREVIATION:mhpC#ECNUMBERS:3.7.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-hydroxy-6-ketonona-2,3-dienedioic acid hydrolase#ABBREVIATION:MhpC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0349)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_hkndd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_op4en_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HKNTDH" name="_2-hydroxy-6-ketononotrienedioate hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HKNTDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + hkntd --&gt; fum + (2) h + op4en</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- see PMID 9603882 and PMID 9098055</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0349#ABBREVIATION:mhpC#ECNUMBERS:3.7.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-hydroxy-6-ketonona-2,3-dienedioic acid hydrolase#ABBREVIATION:MhpC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0349)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_hkntd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_op4en_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HMBS" name="hydroxymethylbilane synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HMBS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.1.8</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (4) ppbng --&gt; hmbil + (4) nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3805#ABBREVIATION:hemC#ECNUMBERS:4.3.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hydroxymethylbilane synthase#ABBREVIATION:HemCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3805)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ppbng_c" stoichiometry="4" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hmbil_c" />
                    <speciesReference species="M_nh4_c" stoichiometry="4" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HMPK1" name="hydroxymethylpyrimidine kinase (ATP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HMPK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.49</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4ahmmp + atp --&gt; 4ampm + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2103#ABBREVIATION:thiD#ECNUMBERS:2.7.4.7,-!-,2.7.1.49#</html:p>
                    <html:p>LOCUS:b2418#ABBREVIATION:pdxK#ECNUMBERS:2.7.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydroxy-phosphomethylpyrimidine kinase and hydroxy-methylpyrimidine kinase#ABBREVIATION:ThiDec#</html:p>
                    <html:p>NAME:pyridoxal-pyridoxamine kinase and hydroxymethylpyrimidine kinase#ABBREVIATION:PdxK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2103) or (b2418)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4ahmmp_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4ampm_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HOPNTAL" name="_4-hydroxy-2-oxopentanoate aldolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HOPNTAL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 4h2opntn --&gt; acald + pyr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg reaction R00750)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0352#ABBREVIATION:mhpE#ECNUMBERS:4.1.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_4-hydroxy-2-keto-pentanoate aldolase#ABBREVIATION:MhpE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0352)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4h2opntn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPPK2" name="_6-hydroxymethyl-dihydropterin pyrophosphokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HPPK2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 6hmhpt + atp --&gt; 6hmhptpp + amp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Neidhardt pg 667</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0142#ABBREVIATION:folK#ECNUMBERS:2.7.6.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase#ABBREVIATION:FolK#</html:p>
                    <html:p>GENE ASSOCIATION: (b0142)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_6hmhpt_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_6hmhptpp_c" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPPPNDO" name="_2,3-dihydroxypheylpropionate 1,2-dioxygenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HPPPNDO</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 1.13.11.16</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : dhpppn + o2 --&gt; hkndd</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR-</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0348#ABBREVIATION:mhpB#ECNUMBERS:1.13.11.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2,3-dihydroxyphenylpropionate 1,2-dioxygenase#ABBREVIATION:MhpB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0348)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhpppn_c" />
                    <speciesReference species="M_o2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hkndd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPPPNt2r" name="_3-(3-hydroxyphenyl)propionate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_HPPPNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: _3hpppn[e] + h[e] &lt;==&gt; 3hpppn[c] + h[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0353#ABBREVIATION:mhpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative 3-(3-hydroxyphenyl)propionate and 3-hydroxycinnimate transporter, MFS#ABBREVIATION:MhpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0353)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hpppn_e" />
                    <speciesReference species="M_h_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3hpppn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPYRI" name="hydroxypyruvate isomerase">
                <notes>
                    <html:p>Abbreviation: R_HPYRI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.22</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : hpyr &lt;==&gt; 2h3oppan</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0508#ABBREVIATION:hyi#ECNUMBERS:5.3.1.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydroxypyruvate isomerase#ABBREVIATION:Hyi#</html:p>
                    <html:p>GENE ASSOCIATION: (b0508)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hpyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2h3oppan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPYRRx" name="Hydroxypyruvate reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HPYRRx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h + hpyr + nadh --&gt; glyc-R + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1033#ABBREVIATION:ycdW#ECNUMBERS:1.1.1.79#</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>NAME:_2-ketoacid reductase#ABBREVIATION:YcdW#</html:p>
                    <html:p>GENE ASSOCIATION: (b1033) or (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hpyr_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_R_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HPYRRy" name="Hydroxypyruvate reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HPYRRy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h + hpyr + nadph --&gt; glyc-R + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1033#ABBREVIATION:ycdW#ECNUMBERS:1.1.1.79#</html:p>
                    <html:p>LOCUS:b3553#ABBREVIATION:yiaE#ECNUMBERS:1.1.1.79,-!-,1.1.1.215#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-deto-D-gluconate reductase#ABBREVIATION:YiaE#</html:p>
                    <html:p>NAME:_2-ketoacid reductase#ABBREVIATION:YcdW#</html:p>
                    <html:p>GENE ASSOCIATION: (b1033) or (b3553)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hpyr_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_R_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HSDy" name="homoserine dehydrogenase (NADPH)">
                <notes>
                    <html:p>Abbreviation: R_HSDy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.3</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : hom-L + nadp &lt;==&gt; aspsa + h + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0002#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3#</html:p>
                    <html:p>LOCUS:b3940#ABBREVIATION:metL#ECNUMBERS:2.7.2.4,-!-,1.1.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Homoserine dehydrogenase#ABBREVIATION:MetL#</html:p>
                    <html:p>NAME:Aspartate kinase I#ABBREVIATION:ThrA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3940) or (b0002)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hom_L_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aspsa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HSK" name="homoserine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HSK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.39</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + hom-L --&gt; adp + h + phom</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0003#ABBREVIATION:thrB#ECNUMBERS:2.7.1.39#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Homoserine kinase#ABBREVIATION:ThrB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0003)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_hom_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_phom_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HSST" name="homoserine O-succinyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HSST</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.46</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : hom-L + succoa --&gt; coa + suchms</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4013#ABBREVIATION:metA#ECNUMBERS:2.3.1.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:homoserine transsuccinylase#ABBREVIATION:MetA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4013)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hom_L_c" />
                    <speciesReference species="M_succoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_suchms_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HSTPT" name="histidinol-phosphate transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HSTPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.9</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : glu-L + imacp --&gt; akg + hisp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2021#ABBREVIATION:hisC#ECNUMBERS:2.6.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Histidinol phosphate aminotransferase#ABBREVIATION:HisC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2021)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_imacp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_hisp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HXPRT" name="hypoxanthine phosphoribosyltransferase (Hypoxanthine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HXPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.8</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : hxan + prpp --&gt; imp + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Guanine (see GUAPRT) and 6-mercaptopurine can replace hypoxanthine</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0125#ABBREVIATION:hpt#ECNUMBERS:2.4.2.8#</html:p>
                    <html:p>LOCUS:b0238#ABBREVIATION:gpt#ECNUMBERS:2.4.2.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Xanthine guanine phosphoribosyl transferase#ABBREVIATION:Gpt#</html:p>
                    <html:p>NAME:Hypoxanthine phosphoribosyltransferase#ABBREVIATION:Hpt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0238) or (b0125)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hxan_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_imp_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HYD1" name="hydrogenase (ubiquinone-8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HYD1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.18.99.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[c] + h2[c] + q8[c] --&gt; (2) h[e] + q8h2[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- ubiquinone-8 specific</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0972#ABBREVIATION:hyaA#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0973#ABBREVIATION:hyaB#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0974#ABBREVIATION:hyaC#</html:p>
                    <html:p>LOCUS:b2994#ABBREVIATION:hybC#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2997#ABBREVIATION:hybO#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2719#ABBREVIATION:hycG#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b2720#ABBREVIATION:hycF#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2721#ABBREVIATION:hycE#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2722#ABBREVIATION:hycD#</html:p>
                    <html:p>LOCUS:b2723#ABBREVIATION:hycC#</html:p>
                    <html:p>LOCUS:b2724#ABBREVIATION:hycB#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydrogenase I#ABBREVIATION:HyaA#</html:p>
                    <html:p>NAME:hydrogenase II#ABBREVIATION:HybC#</html:p>
                    <html:p>NAME:hydrogenase III#ABBREVIATION:HycB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0974 and b0972 and b0973) or (b2721 and b2723 and b2724 and b2722 and b2720 and b2719) or (b2994 and b2997)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_h2_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HYD2" name="Hydrogenase (menaquinone8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HYD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.18.99.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[c] + h2[c] + mqn8[c] --&gt; (2) h[e] + mql8[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0972#ABBREVIATION:hyaA#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0973#ABBREVIATION:hyaB#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0974#ABBREVIATION:hyaC#</html:p>
                    <html:p>LOCUS:b2994#ABBREVIATION:hybC#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2997#ABBREVIATION:hybO#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydrogenase I#ABBREVIATION:HyaA#</html:p>
                    <html:p>NAME:hydrogenase II#ABBREVIATION:HybC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2994 and b2997) or (b0974 and b0972 and b0973)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_h2_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_mql8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HYD3" name="Hydrogenase (Demethylmenaquinone-8: 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HYD3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.18.99.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: _2dmmq8[c] + (2) h[c] + h2[c] --&gt; 2dmmql8[c] + (2) h[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0972#ABBREVIATION:hyaA#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0973#ABBREVIATION:hyaB#ECNUMBERS:1.12.7.2#</html:p>
                    <html:p>LOCUS:b0974#ABBREVIATION:hyaC#</html:p>
                    <html:p>LOCUS:b2994#ABBREVIATION:hybC#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>LOCUS:b2997#ABBREVIATION:hybO#ECNUMBERS:1.18.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydrogenase I#ABBREVIATION:HyaA#</html:p>
                    <html:p>NAME:hydrogenase II#ABBREVIATION:HybC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0974 and b0972 and b0973) or (b2994 and b2997)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_h2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HYPOE" name="hypothetical enyme" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_HYPOE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + pyam5p --&gt; pi + pydam</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pyam5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_pydam_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_HYXNt" name="Hypoxanthine transport">
                <notes>
                    <html:p>Abbreviation: R_HYXNt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: hxan[e] &lt;==&gt; hxan[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hxan_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hxan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ICDHyr" name="isocitrate dehydrogenase (NADP)">
                <notes>
                    <html:p>Abbreviation: R_ICDHyr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.42</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : icit + nadp &lt;==&gt; akg + co2 + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Two reactions (ICDH1 and ICDH2) for isocitrate dehydrogenase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1136#ABBREVIATION:icd#ECNUMBERS:1.1.1.42#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isocitrate dehydrogenase#ABBREVIATION:Icd#</html:p>
                    <html:p>GENE ASSOCIATION: (b1136)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_icit_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ICHORSi" name="Isochorismate Synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ICHORSi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : chor --&gt; ichor</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added irreversible form of ICHORS</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0593#ABBREVIATION:entC#ECNUMBERS:5.4.4.2#</html:p>
                    <html:p>LOCUS:b2265#ABBREVIATION:menF#ECNUMBERS:5.4.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isochorismate synthase I#ABBREVIATION:MenF#</html:p>
                    <html:p>NAME:isochorismate synthase II#ABBREVIATION:EntC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2265) or (b0593)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_chor_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ichor_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ICHORT" name="isochorismatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ICHORT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.3.2.1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + ichor --&gt; 23ddhb + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0595#ABBREVIATION:entB#ECNUMBERS:3.3.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isochorismatase#ABBREVIATION:EntB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0595)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ichor_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23ddhb_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ICL" name="Isocitrate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ICL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.1</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : icit --&gt; glx + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>IF
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4015#ABBREVIATION:aceA#ECNUMBERS:4.1.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isocitrate lyase#ABBREVIATION:AceA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4015)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_icit_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IDOND" name="L-idonate 5-dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_IDOND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 5dglcn + h + nadh &lt;==&gt; idon-L + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4267#ABBREVIATION:idnD#ECNUMBERS:1.1.1.264#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-idonate 5-dehydrogenase#ABBREVIATION:IdnD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4267)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5dglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_idon_L_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IDOND2" name="L-indonate 5-dehydrogenase (NADP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IDOND2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 5dglcn + h + nadph --&gt; idon-L + nadp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4267#ABBREVIATION:idnD#ECNUMBERS:1.1.1.264#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-idonate 5-dehydrogenase#ABBREVIATION:IdnD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4267)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5dglcn_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_idon_L_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IDONt2r" name="L-idonate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_IDONt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + idon-L[e] &lt;==&gt; h[c] + idon-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4265#ABBREVIATION:idnT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GntP family L-idonate transporter#ABBREVIATION:IdnT#</html:p>
                    <html:p>GENE ASSOCIATION: (b4265)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_idon_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_idon_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IG3PS" name="Imidazole-glycerol-3-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IG3PS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : gln-L + prlp --&gt; aicar + eig3p + glu-L + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Essential in L-histidine synthesis: No definite EC number assigned: EC 2.4.2.-; HisF cyclase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2023#ABBREVIATION:hisH#ECNUMBERS:2.4.2.-#</html:p>
                    <html:p>LOCUS:b2025#ABBREVIATION:hisF#ECNUMBERS:2.4.2.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Imadazoleglycerol phosphate synthase#ABBREVIATION:HisF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2023 and b2025)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_prlp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aicar_c" />
                    <speciesReference species="M_eig3p_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IGPDH" name="imidazoleglycerol-phosphate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IGPDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.19</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : eig3p --&gt; h2o + imacp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2022#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2022)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_eig3p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_imacp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IGPS" name="indole-3-glycerol-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IGPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.48</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 2cpr5p + h --&gt; 3ig3p + co2 + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1262#ABBREVIATION:trpC#ECNUMBERS:5.3.1.24,-!-,4.1.1.48#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosyl anthranilate isomerase#ABBREVIATION:TrpCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1262)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2cpr5p_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3ig3p_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ILETA" name="isoleucine transaminase">
                <notes>
                    <html:p>Abbreviation: R_ILETA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.42</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : akg + ile-L &lt;==&gt; 3mop + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3770#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3770)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_ile_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3mop_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ILEabc" name="L-isoleucine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ILEabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + ile-L[e] --&gt; adp[c] + h[c] + ile-L[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3454#ABBREVIATION:livF#</html:p>
                    <html:p>LOCUS:b3455#ABBREVIATION:livG#</html:p>
                    <html:p>LOCUS:b3456#ABBREVIATION:livM#</html:p>
                    <html:p>LOCUS:b3457#ABBREVIATION:livH#</html:p>
                    <html:p>LOCUS:b3460#ABBREVIATION:livJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivJ#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivF#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivG#</html:p>
                    <html:p>NAME:ABC, branced chain AA (membrane)#ABBREVIATION:LivH#</html:p>
                    <html:p>NAME:ABC, branced chain AA #ABBREVIATION:LivM#</html:p>
                    <html:p>GENE ASSOCIATION: (b3455) and (b3460) and (b3457) and (b3454) and (b3456)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ile_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ile_L_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ILEt2r" name="L-isoleucine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_ILEt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ile-L[e] &lt;==&gt; h[c] + ile-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0401#ABBREVIATION:brnQ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched chain amino acid transport system II carrier protein#ABBREVIATION:BrnQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0401)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ile_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ile_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IMPC" name="IMP cyclohydrolase">
                <notes>
                    <html:p>Abbreviation: R_IMPC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.10</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + imp &lt;==&gt; fprica</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4006#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH#</html:p>
                    <html:p>GENE ASSOCIATION: (b4006)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_imp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fprica_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IMPD" name="IMP dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IMPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.205</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + imp + nad --&gt; h + nadh + xmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2508#ABBREVIATION:guaB#ECNUMBERS:1.1.1.205#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Inosine-5'-monophosphate dehydrogenase#ABBREVIATION:GuaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2508)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_imp_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_xmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_INDOLEt2r" name="Indole transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_INDOLEt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + indole[e] &lt;==&gt; h[c] + indole[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3161#ABBREVIATION:mtr#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:HAAP, tryptophan transport#ABBREVIATION:Mtr#</html:p>
                    <html:p>GENE ASSOCIATION: (b3161)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_indole_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_indole_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_INSK" name="insosine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_INSK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.73</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + ins --&gt; adp + h + imp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0477#ABBREVIATION:gsk#ECNUMBERS:2.7.1.73#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Insosine-guanosine kinase#ABBREVIATION:Gsk#</html:p>
                    <html:p>GENE ASSOCIATION: (b0477)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ins_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_imp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_INSt2r" name="inosine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_INSt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ins[e] &lt;==&gt; h[c] + ins[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ins_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ins_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPDDIi" name="isopentenyl-diphosphate D-isomerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IPDDIi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.3.2</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ipdp --&gt; dmpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added irreversible form of IPDDI</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2889#ABBREVIATION:idi#ECNUMBERS:5.3.3.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isopentenyl diphosphate isomerase#ABBREVIATION:Idi#</html:p>
                    <html:p>GENE ASSOCIATION: (b2889)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ipdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dmpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPDPS" name="_1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (ipdp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IPDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h + h2mb4p + nadh --&gt; h2o + ipdp + nad</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR- unsure about cofactor stoichiometry</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0029#ABBREVIATION:ispH#ECNUMBERS:1.17.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:isoprenyl-pyrophosphate synthase and dimethylallyl diphosphate#ABBREVIATION:LytB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0029)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2mb4p_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ipdp_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPMD" name="_3-isopropylmalate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IPMD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.85</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 3c2hmp + nad --&gt; 3c4mop + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0073#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0073)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3c2hmp_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3c4mop_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPPMIa" name="_3-isopropylmalate dehydratase">
                <notes>
                    <html:p>Abbreviation: R_IPPMIa</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.33</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 3c2hmp &lt;==&gt; 2ippm + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0071#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33#</html:p>
                    <html:p>LOCUS:b0072#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isopropylmalate isomerase#ABBREVIATION:LeuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0072 and b0071)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3c2hmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ippm_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPPMIb" name="_2-isopropylmalate hydratase">
                <notes>
                    <html:p>Abbreviation: R_IPPMIb</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.33</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 2ippm + h2o &lt;==&gt; 3c3hmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Part of IPPMI (3-isopropylmalate dehydrogenase) enzyme
added EC -NCD
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0071#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33#</html:p>
                    <html:p>LOCUS:b0072#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isopropylmalate isomerase#ABBREVIATION:LeuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0072 and b0071)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ippm_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3c3hmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_IPPS" name="_2-isopropylmalate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_IPPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.12</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 3mob + accoa + h2o --&gt; 3c3hmp + coa + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0074#ABBREVIATION:leuA#ECNUMBERS:4.1.3.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isopropylmalate synthase#ABBREVIATION:LeuA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0074)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3mob_c" />
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3c3hmp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KARA1i" name="acetohydroxy acid isomeroreductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KARA1i</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.86</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : alac-S + h + nadph --&gt; 23dhmb + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>used to be named AHAI; renamed for consistency; irreversible form of KARA1i  - NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3774#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3774)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alac_S_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23dhmb_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KARA2i" name="ketol-acid reductoisomerase (2-Aceto-2-hydroxybutanoate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KARA2i</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.86</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 2ahbut + h + nadph --&gt; 23dhmp + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - added irreversible form of KARA2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3774#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3774)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ahbut_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_23dhmp_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KAS14" name="beta-ketoacyl-ACP synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KAS14</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.41</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : acACP + h + malACP --&gt; ACP + actACP + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
AMF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1095) or (b2323)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acACP_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malACP_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KAS15" name="beta-ketoacyl-ACP synthase (2)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KAS15</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + h + malACP --&gt; actACP + co2 + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
AMF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1091#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1091)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malACP_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_actACP_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KAS16" name="_3-hydroxy-myristoyl-ACP synthesis" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KAS16</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : ddcaACP + (2) h + malACP + nadph --&gt; 3hmrsACP + ACP + co2 + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- takes C12:0-ACP fatty acid part way through the elongation cycle.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1093#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100#</html:p>
                    <html:p>LOCUS:b1095#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF#</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabGec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2323) and (b1093) or (b1095) and (b1093)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ddcaACP_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_malACP_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3hmrsACP_c" />
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KDOCT2" name="_3-deoxy-manno-octulosonate cytidylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KDOCT2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.38</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ctp + kdo --&gt; ckdo + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- makes the ring form of kdo</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0918#ABBREVIATION:kdsB#ECNUMBERS:2.7.7.38#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:CMP-3-deoxy-D-manno-octulosonate transferase#ABBREVIATION:KdsBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0918)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_kdo_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ckdo_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KDOPP" name="_3-deoxy-manno-octulosonate-8-phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KDOPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.45</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + kdo8p --&gt; kdo + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_kdo8p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_kdo_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KDOPS" name="_3-deoxy -D-manno-octulosonic -acid 8-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KDOPS</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 4.1.2.16</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ara5p + h2o + pep --&gt; kdo8p + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>TDV (5-31-2004)
new EC from Kegg: 2.5.1.55</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1215#ABBREVIATION:kdsA#ECNUMBERS:2.5.1.55#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-deoxy-d-manno-octulosonic acid 8-phosphate synthetase#ABBREVIATION:KdsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1215)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ara5p_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_kdo8p_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_KG6PDC" name="_3-keto-L-gulonate 6-phosphate decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_KG6PDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 3dhgulnp + h --&gt; co2 + xu5p-L</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3581#ABBREVIATION:sgbH#ECNUMBERS:4.1.2.-#</html:p>
                    <html:p>LOCUS:b4196#ABBREVIATION:ulaD#ECNUMBERS:4.1.2.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-keto-L-gulonate 6-phosphate decarboxylase#ABBREVIATION:SgaH#</html:p>
                    <html:p>NAME:_3-keto-L-gulonate 6-phosphate decarboxylase#ABBREVIATION:SgbH#</html:p>
                    <html:p>GENE ASSOCIATION: (b4196) or (b3581)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3dhgulnp_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_xu5p_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_Kabc" name="Potassium ABC transporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_Kabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + k[e] --&gt; adp[c] + h[c] + k[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0696#ABBREVIATION:kdpC#ECNUMBERS:3.6.3.12#</html:p>
                    <html:p>LOCUS:b0697#ABBREVIATION:kdpB#ECNUMBERS:3.6.3.12#</html:p>
                    <html:p>LOCUS:b0698#ABBREVIATION:kdpA#ECNUMBERS:3.6.3.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:P-type ATPase, K transport#ABBREVIATION:KdpABC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0698 and b0697 and b0696)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_k_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_k_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_Kt2r" name="potassium reversible transport  via proton symport">
                <notes>
                    <html:p>Abbreviation: R_Kt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + k[e] &lt;==&gt; h[c] + k[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1363#ABBREVIATION:trkG#</html:p>
                    <html:p>LOCUS:b3849#ABBREVIATION:trkH#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Potassium uptake#ABBREVIATION:TrkG#</html:p>
                    <html:p>NAME:Potassium H+ symporter#ABBREVIATION:TrkH#</html:p>
                    <html:p>GENE ASSOCIATION: (b1363) or (b3849)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_k_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_k_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LACZ" name="b-galactosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LACZ</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.1.23</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + lcts --&gt; gal + glc-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Some enzymes in this group hydrolyse a-L-arabinosides; some animal enzymes also hydrolyse b-D-fucosides and b-D-glucosides; cf. EC 3.2.1.108 lactase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0344#ABBREVIATION:lacZ#ECNUMBERS:3.2.1.23#</html:p>
                    <html:p>LOCUS:b2132#ABBREVIATION:bglX#ECNUMBERS:3.2.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:beta-D-glucosidase#ABBREVIATION:BglX#</html:p>
                    <html:p>NAME:beta-D-galactosidase#ABBREVIATION:LacZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0344) or (b2132)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_lcts_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gal_c" />
                    <speciesReference species="M_glc_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LCAD" name="lactaldehyde dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_LCAD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.21</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + lald-L + nad &lt;==&gt; (2) h + lac-L + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0356#ABBREVIATION:frmA#ECNUMBERS:1.1.1.1,-!-,1.2.1.1#</html:p>
                    <html:p>LOCUS:b1300#ABBREVIATION:puuC#ECNUMBERS:1.2.1.3#</html:p>
                    <html:p>LOCUS:b1415#ABBREVIATION:aldA#ECNUMBERS:1.2.1.22#</html:p>
                    <html:p>LOCUS:b3588#ABBREVIATION:aldB#ECNUMBERS:1.2.1.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aldehyde dehydrogenase A#ABBREVIATION:AldA#</html:p>
                    <html:p>NAME:aldehyde dehydrogenase B#ABBREVIATION:AldB#</html:p>
                    <html:p>NAME:Putative alcohol dehdrogenase III#ABBREVIATION:AdhC#</html:p>
                    <html:p>NAME:aldehyde dehdrogenase#ABBREVIATION:AldH#</html:p>
                    <html:p>GENE ASSOCIATION: (b1300) or (b1415) or (b0356) or (b3588)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_lald_L_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_lac_L_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LCARS" name="lacaldehyde reductase (S-propane-1,2-diol forming)">
                <notes>
                    <html:p>Abbreviation: R_LCARS</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 1.1.1.77</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h + lald-L + nadh &lt;==&gt; 12ppd-S + nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2799#ABBREVIATION:fucO#ECNUMBERS:1.1.1.77#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-12,-propanediol oxidoreductase#ABBREVIATION:FucO#</html:p>
                    <html:p>GENE ASSOCIATION: (b2799)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lald_L_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_12ppd_S_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LCTSt" name="Lactose transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_LCTSt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + lcts[e] &lt;==&gt; h[c] + lcts[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0343#ABBREVIATION:lacY#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, galactoside permease#ABBREVIATION:LacY#</html:p>
                    <html:p>GENE ASSOCIATION: (b0343)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_lcts_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lcts_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LDH_D" name="D-lactate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_LDH_D</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.28</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : lac-D + nad &lt;==&gt; h + nadh + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>See also LDL_L</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1380#ABBREVIATION:ldhA#ECNUMBERS:1.1.1.28#</html:p>
                    <html:p>LOCUS:b2133#ABBREVIATION:dld#ECNUMBERS:1.1.1.28#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-lactate dehydrogenase#ABBREVIATION:Dld#</html:p>
                    <html:p>NAME:D-lactate dehydrogenase II#ABBREVIATION:Ldh#</html:p>
                    <html:p>GENE ASSOCIATION: (b2133) or (b1380)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_D_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LDH_D2" name="D-lactate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LDH_D2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.2.4</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : lac-D + q8 --&gt; pyr + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2133#ABBREVIATION:dld#ECNUMBERS:1.1.1.28#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-lactate dehydrogenase#ABBREVIATION:Dld#</html:p>
                    <html:p>GENE ASSOCIATION: (b2133)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_D_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LEUTAi" name="leucine transaminase (irreversible)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LEUTAi</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 2.6.1.42</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 4mop + glu-L --&gt; akg + leu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added irreversible form of LEUTA .  Used 2.6.1.42 as the EC instead of 2.6.1.6 (they have the same reaction).</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3770#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42#</html:p>
                    <html:p>LOCUS:b4054#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE#</html:p>
                    <html:p>NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4054) or (b3770)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4mop_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_leu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LEUabc" name="L-leucine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LEUabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + leu-L[e] --&gt; adp[c] + h[c] + leu-L[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3454#ABBREVIATION:livF#</html:p>
                    <html:p>LOCUS:b3455#ABBREVIATION:livG#</html:p>
                    <html:p>LOCUS:b3456#ABBREVIATION:livM#</html:p>
                    <html:p>LOCUS:b3457#ABBREVIATION:livH#</html:p>
                    <html:p>LOCUS:b3458#ABBREVIATION:livK#</html:p>
                    <html:p>LOCUS:b3460#ABBREVIATION:livJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivJ#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivF#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivG#</html:p>
                    <html:p>NAME:ABC, branced chain AA (membrane)#ABBREVIATION:LivH#</html:p>
                    <html:p>NAME:ABC, branced chain AA #ABBREVIATION:LivM#</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3455) and (b3460) and (b3457) and (b3454) and (b3456) or (b3455) and (b3454) and (b3457) and (b3458) and (b3456)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_leu_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_leu_L_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LEUt2r" name="L-leucine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_LEUt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + leu-L[e] &lt;==&gt; h[c] + leu-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0401#ABBREVIATION:brnQ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched chain amino acid transport system II carrier protein#ABBREVIATION:BrnQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0401)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_leu_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_leu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LGTHL" name="lactoylglutathione lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LGTHL</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.4.1.5</html:p>
                    <html:p>SUBSYSTEM: Methylglyoxal Metabolism</html:p>
                    <html:p>Equation: [c] : gthrd + mthgxl --&gt; lgt-S</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1651#ABBREVIATION:gloA#ECNUMBERS:4.4.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glyoxalase#ABBREVIATION:GloA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1651)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gthrd_c" />
                    <speciesReference species="M_mthgxl_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_lgt_S_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPADSS" name="Lipid A disaccaride synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPADSS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.182</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : lipidX + u23ga --&gt; h + lipidAds + udp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0182#ABBREVIATION:lpxB#ECNUMBERS:2.4.1.182#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lipid A disaccharide synthetase#ABBREVIATION:LpxB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0182)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lipidX_c" />
                    <speciesReference species="M_u23ga_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lipidAds_c" />
                    <speciesReference species="M_udp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA1" name="Lysophospholipase L (acyl-glycerophosphoglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpg_EC + h2o --&gt; g3pg + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3pg_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA2" name="Lysophospholipase L (acyl-glycerophosphoethanolamine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpe_EC + h2o --&gt; g3pe + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpe_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3pe_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA3" name="Lysophospholipase L (acyl-glycerophosphocholine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpc_EC + h2o --&gt; g3pc + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpc_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3pc_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA4" name="Lysophospholipase L (acyl transfer to phosphatidylglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpe_EC + (0.02) pg_EC --&gt; (0.02) apg_EC + g3pe</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpe_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_apg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_g3pe_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA5" name="Lysophospholipase L (acyl transfer to phosphatidylglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpc_EC + (0.02) pg_EC --&gt; (0.02) apg_EC + g3pc</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpc_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_apg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_g3pc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPLIPA6" name="Lysophospholipase L (acyl transfer to phosphatidylglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPLIPA6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (0.02) agpg_EC + (0.02) pg_EC --&gt; (0.02) apg_EC + g3pg</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3825#ABBREVIATION:pldB#ECNUMBERS:3.1.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lysophospholipase L(2)#ABBREVIATION:PldB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3825)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_agpg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_apg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_g3pg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LPSSYN_EC" name="Lipopolysaccharide synthesis (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LPSSYN_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : (3) adphep-LD + (2) cdpea + (3) ckdo + lipa + (2) udpg --&gt; (3) adp + (2) cdp + (3) cmp + (10) h + lps_EC + (2) udp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- assumed that each sugar generates a H upon being added to the chain</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3620#ABBREVIATION:rfaF#ECNUMBERS:2.-.-.-#</html:p>
                    <html:p>LOCUS:b3621#ABBREVIATION:rfaC#ECNUMBERS:2.-.-.-#</html:p>
                    <html:p>LOCUS:b3622#ABBREVIATION:rfaL#</html:p>
                    <html:p>LOCUS:b3626#ABBREVIATION:rfaJ#ECNUMBERS:2.4.1.58#</html:p>
                    <html:p>LOCUS:b3627#ABBREVIATION:rfaI#ECNUMBERS:2.4.1.44#</html:p>
                    <html:p>LOCUS:b3631#ABBREVIATION:rfaG#ECNUMBERS:2.4.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Lipopolysaccharide heptosyltransferase-1#ABBREVIATION:RfaC#</html:p>
                    <html:p>NAME:O-antigen ligase#ABBREVIATION:RfaL#</html:p>
                    <html:p>NAME:UDP-D-gluose:(galactosyl)lipopolysaccharide glucosyltransferase#ABBREVIATION:RfaJec#</html:p>
                    <html:p>NAME:UDP-D-galactose:(glucosyl)lipopolysaccharide -alpha-1,3-D-galactosyltransferase#ABBREVIATION:RfaI#</html:p>
                    <html:p>NAME:glucosyltransferase I#ABBREVIATION:RfaG#</html:p>
                    <html:p>NAME:ADP-heptose; LPS heptosyltransferase I#ABBREVIATION:RfaF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3622) and (b3626) and (b3631) and (b3627) and (b3621) and (b3620)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adphep_LD_c" stoichiometry="3" />
                    <speciesReference species="M_cdpea_c" stoichiometry="2" />
                    <speciesReference species="M_ckdo_c" stoichiometry="3" />
                    <speciesReference species="M_lipa_c" />
                    <speciesReference species="M_udpg_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" stoichiometry="3" />
                    <speciesReference species="M_cdp_c" stoichiometry="2" />
                    <speciesReference species="M_cmp_c" stoichiometry="3" />
                    <speciesReference species="M_h_c" stoichiometry="10" />
                    <speciesReference species="M_lps_EC_c" />
                    <speciesReference species="M_udp_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LYSDC" name="lysine decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LYSDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.18</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : h + lys-L --&gt; 15dap + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0186#ABBREVIATION:ldcC#ECNUMBERS:4.1.1.18#</html:p>
                    <html:p>LOCUS:b4131#ABBREVIATION:cadA#ECNUMBERS:4.1.1.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:lysine decarboxylase II#ABBREVIATION:LdcC#</html:p>
                    <html:p>NAME:lysine decarboxylase I#ABBREVIATION:CadA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0186) or (b4131)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lys_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_15dap_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LYSabc" name="L-lysine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_LYSabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + lys-L[e] --&gt; adp[c] + h[c] + lys-L[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2306#ABBREVIATION:hisP#</html:p>
                    <html:p>LOCUS:b2307#ABBREVIATION:hisM#</html:p>
                    <html:p>LOCUS:b2308#ABBREVIATION:hisQ#</html:p>
                    <html:p>LOCUS:b2310#ABBREVIATION:argT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, lys/arg/ornithine (periplasm)#ABBREVIATION:ArgT#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/orn (membrane)#ABBREVIATION:HisM#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (atp)#ABBREVIATION:HisP#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (membrane)#ABBREVIATION:HisQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2310) and (b2307) and (b2308) and (b2306)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_lys_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lys_L_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_LYSt2r" name="L-lysine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_LYSt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + lys-L[e] &lt;==&gt; h[c] + lys-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2156#ABBREVIATION:lysP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, lysine proton symport#ABBREVIATION:LysP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2156)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_lys_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lys_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_L_LACD2" name="L-Lactate dehydrogenase (ubiquinone)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_L_LACD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.2.3</html:p>
                    <html:p>Equation: [c] : lac-L + q8 --&gt; pyr + q8h2</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3605#ABBREVIATION:lldD#ECNUMBERS:1.1.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-lactate dehydrogenase#ABBREVIATION:LldD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3605)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_L_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_L_LACD3" name="L-Lactate dehydrogenase (menaquinone)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_L_LACD3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.2.3</html:p>
                    <html:p>Equation: [c] : lac-L + mqn8 --&gt; mql8 + pyr</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3605#ABBREVIATION:lldD#ECNUMBERS:1.1.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-lactate dehydrogenase#ABBREVIATION:LldD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3605)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_lac_L_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_L_LACt2r" name="L-lactate reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_L_LACt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + lac-L[e] &lt;==&gt; h[c] + lac-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2975#ABBREVIATION:yghK#</html:p>
                    <html:p>LOCUS:b3603#ABBREVIATION:lldP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:LctP transporter, L-lactate/D-lactate/Glycolate H symporter#ABBREVIATION:LldP#</html:p>
                    <html:p>NAME:putative L-lactate permease, LctP family#ABBREVIATION:GlcA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2975) or (b3603)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_lac_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lac_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_M1PD" name="mannitol-1-phosphate 5-dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_M1PD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.17</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : mnl1p + nad &lt;==&gt; f6p + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3600#ABBREVIATION:mtlD#ECNUMBERS:1.1.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:mannitol-1-phosphate dehydrogenase#ABBREVIATION:MtlD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3600)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mnl1p_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MACPD" name="Malonyl-ACP decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MACPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : h + malACP --&gt; acACP + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2323#ABBREVIATION:fabB#ECNUMBERS:2.3.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-oxoacyl-[acyl-carrier-protein] synthase I#ABBREVIATION:FabB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2323)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malACP_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acACP_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALS" name="malate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.2</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : accoa + glx + h2o --&gt; coa + h + mal-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2976#ABBREVIATION:glcB#ECNUMBERS:2.3.3.9#</html:p>
                    <html:p>LOCUS:b4014#ABBREVIATION:aceB#ECNUMBERS:2.3.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:malate synthase A#ABBREVIATION:AceB#</html:p>
                    <html:p>NAME:malate synthase G#ABBREVIATION:GlcB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4014) or (b2976)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mal_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTHXabc" name="maltohexaose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTHXabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + malthx[e] --&gt; adp[c] + h[c] + malthx[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4032#ABBREVIATION:malG#</html:p>
                    <html:p>LOCUS:b4033#ABBREVIATION:malF#</html:p>
                    <html:p>LOCUS:b4034#ABBREVIATION:malE#</html:p>
                    <html:p>LOCUS:b4035#ABBREVIATION:malK#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>NAME:ABC maltose transport (peri_bind)#ABBREVIATION:MalE#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalF#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalG#</html:p>
                    <html:p>NAME:ABC maltose transport (atp_bind)#ABBREVIATION:MalK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4032) and (b4035) and (b4033) and (b4036) and (b4034)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malthx_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malthx_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTPTabc" name="maltopentaose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTPTabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + maltpt[e] --&gt; adp[c] + h[c] + maltpt[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4032#ABBREVIATION:malG#</html:p>
                    <html:p>LOCUS:b4033#ABBREVIATION:malF#</html:p>
                    <html:p>LOCUS:b4034#ABBREVIATION:malE#</html:p>
                    <html:p>LOCUS:b4035#ABBREVIATION:malK#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>NAME:ABC maltose transport (peri_bind)#ABBREVIATION:MalE#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalF#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalG#</html:p>
                    <html:p>NAME:ABC maltose transport (atp_bind)#ABBREVIATION:MalK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4035) and (b4032) and (b4033) and (b4036) and (b4034)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_maltpt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_maltpt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTTRabc" name="Maltotriose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTTRabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + malttr[e] --&gt; adp[c] + h[c] + malttr[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4032#ABBREVIATION:malG#</html:p>
                    <html:p>LOCUS:b4033#ABBREVIATION:malF#</html:p>
                    <html:p>LOCUS:b4034#ABBREVIATION:malE#</html:p>
                    <html:p>LOCUS:b4035#ABBREVIATION:malK#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>NAME:ABC maltose transport (peri_bind)#ABBREVIATION:MalE#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalF#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalG#</html:p>
                    <html:p>NAME:ABC maltose transport (atp_bind)#ABBREVIATION:MalK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4032) and (b4035) and (b4033) and (b4036) and (b4034)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malttr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malttr_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTTTRabc" name="maltotetraose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTTTRabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + maltttr[e] --&gt; adp[c] + h[c] + maltttr[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4032#ABBREVIATION:malG#</html:p>
                    <html:p>LOCUS:b4033#ABBREVIATION:malF#</html:p>
                    <html:p>LOCUS:b4034#ABBREVIATION:malE#</html:p>
                    <html:p>LOCUS:b4035#ABBREVIATION:malK#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>NAME:ABC maltose transport (peri_bind)#ABBREVIATION:MalE#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalF#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalG#</html:p>
                    <html:p>NAME:ABC maltose transport (atp_bind)#ABBREVIATION:MalK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4035) and (b4032) and (b4033) and (b4036) and (b4034)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_maltttr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_maltttr_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTabc" name="maltose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + malt[e] --&gt; adp[c] + h[c] + malt[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4032#ABBREVIATION:malG#</html:p>
                    <html:p>LOCUS:b4033#ABBREVIATION:malF#</html:p>
                    <html:p>LOCUS:b4034#ABBREVIATION:malE#</html:p>
                    <html:p>LOCUS:b4035#ABBREVIATION:malK#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>NAME:ABC maltose transport (peri_bind)#ABBREVIATION:MalE#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalF#</html:p>
                    <html:p>NAME:ABC maltose transport (membrane)#ABBREVIATION:MalG#</html:p>
                    <html:p>NAME:ABC maltose transport (atp_bind)#ABBREVIATION:MalK#</html:p>
                    <html:p>GENE ASSOCIATION: (b4035) and (b4032) and (b4033) and (b4036) and (b4034)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malt_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_malt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALTpts" name="maltose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALTpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: malt[e] + pep[c] --&gt; malt6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1621#ABBREVIATION:malX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2417#ABBREVIATION:crr#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b4036#ABBREVIATION:lamB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, Glucose/Trehalose/Maltose IIA#ABBREVIATION:Crr#</html:p>
                    <html:p>NAME:PTS, Maltose IIC#ABBREVIATION:MalX#</html:p>
                    <html:p>NAME:Maltoporin#ABBREVIATION:LamB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1621) and (b2415) and (b2417) and (b2416) and (b4036)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malt_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_malt6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALt2_2" name="Malate transport via proton symport (2 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALt2_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (2) h[e] + mal-L[e] --&gt; (2) h[c] + mal-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3528#ABBREVIATION:dctA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3528)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_mal_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_mal_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MALt2_3" name="Malate transport via proton symport (3 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MALt2_3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (3) h[e] + mal-L[e] --&gt; (3) h[c] + mal-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4123#ABBREVIATION:dcuB#</html:p>
                    <html:p>LOCUS:b4138#ABBREVIATION:dcuA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Anaerobic C4-dicarboxylate transporter protein#ABBREVIATION:DcuA#</html:p>
                    <html:p>NAME:anaerobic C4-dicarboxylate transporter#ABBREVIATION:DcuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4123) or (b4138)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="3" />
                    <speciesReference species="M_mal_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_mal_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MAN1PT2" name="mannose-1-phosphate guanylyltransferase (GDP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MAN1PT2</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 2.7.7.22</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gdp + h + man1p --&gt; gdpmann + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2049#ABBREVIATION:cpsB#ECNUMBERS:2.7.7.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:mannose 1-phosphate guanyltransferase#ABBREVIATION:ManC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2049)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_man1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdpmann_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MAN6PI" name="mannose-6-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_MAN6PI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.8</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : man6p &lt;==&gt; f6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1613#ABBREVIATION:manA#ECNUMBERS:5.3.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:mannose-6-phosphate isomerase#ABBREVIATION:ManA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1613)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MAN6Pt6_2" name="Mannose-6-phosphate transport via phosphate antiport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MAN6Pt6_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: man6p[e] + (2) pi[c] --&gt; man6p[c] + (2) pi[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3666#ABBREVIATION:uhpT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, hexose phosphate:phosphate transporter#ABBREVIATION:UhpT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3666)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man6p_e" />
                    <speciesReference species="M_pi_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_man6p_c" />
                    <speciesReference species="M_pi_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MANAO" name="Mannonate oxidoreductase">
                <notes>
                    <html:p>Abbreviation: R_MANAO</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 1.1.1.57</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : mana + nad &lt;==&gt; fruur + h + nadh</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4323#ABBREVIATION:uxuB#ECNUMBERS:1.1.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-mannonate oxidoreductase#ABBREVIATION:UxuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4323)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mana_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fruur_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MANpts" name="D-mannose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MANpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: man[e] + pep[c] --&gt; man6p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1817#ABBREVIATION:manX#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b1818#ABBREVIATION:manY#</html:p>
                    <html:p>LOCUS:b1819#ABBREVIATION:manZ#</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, mannose IIA#ABBREVIATION:ManX#</html:p>
                    <html:p>NAME:PTS, mannose IIC#ABBREVIATION:ManY#</html:p>
                    <html:p>NAME:PTS, mannose IID#ABBREVIATION:ManZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b1818) and (b1819) and (b1817)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_man6p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MCITD" name="_2-methylcitrate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MCITD</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.2.1.79</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2mcit --&gt; 2mcacn + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0334#ABBREVIATION:prpD#ECNUMBERS:4.2.1.79#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-methylcitrate dehydratase#ABBREVIATION:PrpD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0334)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2mcit_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2mcacn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MCITL2" name="methylisocitrate lyase">
                <notes>
                    <html:p>Abbreviation: R_MCITL2</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.1.3.30</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : micit &lt;==&gt; pyr + succ</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0331#ABBREVIATION:prpB#ECNUMBERS:4.1.3.30#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-methylisocitrate lyase#ABBREVIATION:PrpB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0331)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_micit_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MCITS" name="_2-methylcitrate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MCITS</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.1.3.31</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + oaa + ppcoa --&gt; 2mcit + coa + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>NCD
new EC is 2.3.3.5 - NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0333#ABBREVIATION:prpC#ECNUMBERS:2.3.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:methylcitrate synthase#ABBREVIATION:PrpC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0333)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_oaa_c" />
                    <speciesReference species="M_ppcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2mcit_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MCOATA" name="Malonyl-CoA-ACP transacylase">
                <notes>
                    <html:p>Abbreviation: R_MCOATA</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 2.3.1.39</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : ACP + malcoa &lt;==&gt; coa + malACP</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1092#ABBREVIATION:fabD#ECNUMBERS:2.3.1.39#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Malonyl coenzyme A-acyl carrier protein transacylase#ABBREVIATION:FabD#</html:p>
                    <html:p>GENE ASSOCIATION: (b1092)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_malcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_malACP_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MDH" name="malate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_MDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.37</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : mal-L + nad &lt;==&gt; h + nadh + oaa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3236#ABBREVIATION:mdh#ECNUMBERS:1.1.1.37#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:malate dehydrogenase#ABBREVIATION:Mdh#</html:p>
                    <html:p>GENE ASSOCIATION: (b3236)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MDH2" name="Malate dehydrogenase (ubiquinone 8 as acceptor)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MDH2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.99.16</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : mal-L + q8 --&gt; oaa + q8h2</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2210#ABBREVIATION:mqo#ECNUMBERS:1.1.99.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Malate dehydrogenase#ABBREVIATION:Mqo#</html:p>
                    <html:p>GENE ASSOCIATION: (b2210)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_oaa_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MDH3" name="Malate dehydrogenase (menaquinone 8 as acceptor)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MDH3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.99.16</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : mal-L + mqn8 --&gt; mql8 + oaa</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2210#ABBREVIATION:mqo#ECNUMBERS:1.1.99.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Malate dehydrogenase#ABBREVIATION:Mqo#</html:p>
                    <html:p>GENE ASSOCIATION: (b2210)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_c" />
                    <speciesReference species="M_mqn8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MDRPD" name="_5-Methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MDRPD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 5mdru1p --&gt; dkmpp + h2o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- Based on reaction given for B. subtilis (Sekowska A and A. Danchin paper(2002) )</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mdru1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dkmpp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ME1" name="malic enzyme (NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ME1</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 1.1.1.38</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : mal-L + nad --&gt; co2 + nadh + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1479#ABBREVIATION:sfcA#ECNUMBERS:1.1.1.38#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:malic enzyme (NAD)#ABBREVIATION:Sfc#</html:p>
                    <html:p>GENE ASSOCIATION: (b1479)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ME2" name="malic enzyme (NADP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ME2</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 1.1.1.40</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : mal-L + nadp --&gt; co2 + nadph + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2463#ABBREVIATION:maeB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Malic enzyme (NADP)#ABBREVIATION:Mae#</html:p>
                    <html:p>GENE ASSOCIATION: (b2463)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mal_L_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MECDPDH" name="_2C-methyl-D-erythritol 2,4 cyclodiphosphate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MECDPDH</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2mecdp + h --&gt; h2mb4p + h2o</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR- involved in ipdp and dmpp biosynthesis.  Not sure of enzyme name or H2O.  Had to add H to mass balance, charge doesn&amp;apos;t balance
EC 1.17.4.3</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2515#ABBREVIATION:ispG#ECNUMBERS:1.17.4.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-C-methyl-D-erythritol 2,4-cyclodiphosphate dehydratase#ABBREVIATION:GcpE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2515)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2mecdp_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2mb4p_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MECDPS" name="_2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MECDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2p4c2me --&gt; 2mecdp + cmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC 4.6.1.12</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2746#ABBREVIATION:ispF#ECNUMBERS:4.6.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2C-methyl-D-erythritol2,4-cyclodiphosphate synthase#ABBREVIATION:IspF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2746)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2p4c2me_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2mecdp_c" />
                    <speciesReference species="M_cmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MELIBt2" name="melibiose transport in via symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MELIBt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + melib[e] --&gt; h[c] + melib[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD	</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4120#ABBREVIATION:melB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:GPH, Melibiose permease II#ABBREVIATION:MelB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4120)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_melib_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_melib_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MEPCT" name="_2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MEPCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2me4p + ctp + h --&gt; 4c2me + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC 2.7.7.60</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2747#ABBREVIATION:ispD#ECNUMBERS:2.7.7.60#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_4-diphosphocytidyl-2C-methyl-D-eryritol synthase#ABBREVIATION:IspD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2747)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2me4p_c" />
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4c2me_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_METAT" name="methionine adenosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_METAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.6</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + h2o + met-L --&gt; amet + pi + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2942#ABBREVIATION:metK#ECNUMBERS:2.5.1.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:methionine adenosyltransferase I#ABBREVIATION:MetK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2942)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_met_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amet_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_METDabc" name="D-methionine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_METDabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + met-D[e] --&gt; adp[c] + h[c] + met-D[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0197#ABBREVIATION:metQ#</html:p>
                    <html:p>LOCUS:b0198#ABBREVIATION:metI#</html:p>
                    <html:p>LOCUS:b0199#ABBREVIATION:metN#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, D-methione (periplasm)#ABBREVIATION:MetQ#</html:p>
                    <html:p>NAME:ABC, DL-methionine (membrane)#ABBREVIATION:MetI#</html:p>
                    <html:p>NAME:ABC, DL-methionine (atp)#ABBREVIATION:MetN#</html:p>
                    <html:p>GENE ASSOCIATION: (b0197) and (b0199) and (b0198)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_met_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_met_D_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_METS" name="methionine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_METS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.1.1.13</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : 5mthf + hcys-L --&gt; met-L + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3829#ABBREVIATION:metE#ECNUMBERS:2.1.1.14#</html:p>
                    <html:p>LOCUS:b4019#ABBREVIATION:metH#ECNUMBERS:2.1.1.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Cobalamin dependent methionine synthase#ABBREVIATION:MetH#</html:p>
                    <html:p>NAME:Cobalamin independent methionine synthase#ABBREVIATION:MetE#</html:p>
                    <html:p>GENE ASSOCIATION: (b4019) or (b3829)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mthf_c" />
                    <speciesReference species="M_hcys_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_met_L_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_METabc" name="L-methionine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_METabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + met-L[e] --&gt; adp[c] + h[c] + met-L[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0197#ABBREVIATION:metQ#</html:p>
                    <html:p>LOCUS:b0198#ABBREVIATION:metI#</html:p>
                    <html:p>LOCUS:b0199#ABBREVIATION:metN#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, D-methione (periplasm)#ABBREVIATION:MetQ#</html:p>
                    <html:p>NAME:ABC, DL-methionine (membrane)#ABBREVIATION:MetI#</html:p>
                    <html:p>NAME:ABC, DL-methionine (atp)#ABBREVIATION:MetN#</html:p>
                    <html:p>GENE ASSOCIATION: (b0197) and (b0199) and (b0198)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_met_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_met_L_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MGSA" name="methylglyoxal synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MGSA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.3.3</html:p>
                    <html:p>SUBSYSTEM: Methylglyoxal Metabolism</html:p>
                    <html:p>Equation: [c] : dhap --&gt; mthgxl + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>Previously EC 4.2.99.11
this rxn represents the enzymatic conversion or non-enzymatic fragmentation of dhap to mthgxl - NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0963#ABBREVIATION:mgsA#ECNUMBERS:4.2.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:methylglyoxal synthase#ABBREVIATION:MgsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0963)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhap_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mthgxl_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MI1PP" name="myo-inositol 1-phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MI1PP</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 3.1.3.25</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + mi1p-D --&gt; inost + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2533#ABBREVIATION:suhB#ECNUMBERS:3.1.3.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:inositol monophosphatase#ABBREVIATION:SuhB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2533)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mi1p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_inost_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MICITD" name="_2-methylisocitrate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MICITD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.99</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2mcacn + h2o --&gt; micit</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0118#ABBREVIATION:acnB#ECNUMBERS:4.2.1.3,-!-,4.2.1.99#</html:p>
                    <html:p>LOCUS:b1276#ABBREVIATION:acnA#ECNUMBERS:4.2.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aconitase A#ABBREVIATION:AcnA#</html:p>
                    <html:p>NAME:aconitase B#ABBREVIATION:AcnB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1276) or (b0118)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2mcacn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_micit_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTG1" name="Maltodextrin glucosidase (maltotriose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MLTG1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + malttr --&gt; glc-D + malt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0403#ABBREVIATION:malZ#ECNUMBERS:3.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin glucosidase#ABBREVIATION:MalZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malttr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_malt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTG2" name="Maltodextrin glucosidase (maltotetraose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MLTG2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + maltttr --&gt; glc-D + malttr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0403#ABBREVIATION:malZ#ECNUMBERS:3.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin glucosidase#ABBREVIATION:MalZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_maltttr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_malttr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTG3" name="Maltodextrin glucosidase (maltopentaose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MLTG3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + maltpt --&gt; glc-D + maltttr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0403#ABBREVIATION:malZ#ECNUMBERS:3.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin glucosidase#ABBREVIATION:MalZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_maltpt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_maltttr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTG4" name="Maltodextrin glucosidase (maltohexaose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MLTG4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + malthx --&gt; glc-D + maltpt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0403#ABBREVIATION:malZ#ECNUMBERS:3.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin glucosidase#ABBREVIATION:MalZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malthx_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_maltpt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTG5" name="Maltodextrin glucosidase (maltoheptaose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MLTG5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + malthp --&gt; glc-D + malthx</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0403#ABBREVIATION:malZ#ECNUMBERS:3.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin glucosidase#ABBREVIATION:MalZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_malthp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                    <speciesReference species="M_malthx_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTP1" name="Maltodextrin phosphorylase (maltopentaose)">
                <notes>
                    <html:p>Abbreviation: R_MLTP1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : maltpt + pi &lt;==&gt; g1p + maltttr</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3417#ABBREVIATION:malP#ECNUMBERS:2.4.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin phosphorylase#ABBREVIATION:MalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3417)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_maltpt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_maltttr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTP2" name="Maltodextrin phosphorylase (maltohexaose)">
                <notes>
                    <html:p>Abbreviation: R_MLTP2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malthx + pi &lt;==&gt; g1p + maltpt</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3417#ABBREVIATION:malP#ECNUMBERS:2.4.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin phosphorylase#ABBREVIATION:MalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3417)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malthx_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_maltpt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MLTP3" name="Maltodextrin phosphorylase (maltoheptaose)">
                <notes>
                    <html:p>Abbreviation: R_MLTP3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : malthp + pi &lt;==&gt; g1p + malthx</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3417#ABBREVIATION:malP#ECNUMBERS:2.4.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:maltodextrin phosphorylase#ABBREVIATION:MalP#</html:p>
                    <html:p>GENE ASSOCIATION: (b3417)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_malthp_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_malthx_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MMCD" name="Methylmalonyl-CoA decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MMCD</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 4.1.1.41</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h + mmcoa-S --&gt; co2 + ppcoa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2919#ABBREVIATION:ygfG#ECNUMBERS:4.1.1.41#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:methylmalonyl-CoA decarboxylase#ABBREVIATION:YgfG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2919)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mmcoa_S_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_ppcoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MME" name="methylmalonyl-CoA epimerase">
                <notes>
                    <html:p>Abbreviation: R_MME</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.99.1</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : mmcoa-R &lt;==&gt; mmcoa-S</html:p>
                    <html:p>Confidence Level: 1</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mmcoa_R_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mmcoa_S_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MMM2" name="Methylmalonyl-CoA mutase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MMM2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.99.2</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : succoa --&gt; mmcoa-R</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2917#ABBREVIATION:yliK#ECNUMBERS:5.4.99.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:methylmalonyl-CoA mutase#ABBREVIATION:Sbm#</html:p>
                    <html:p>GENE ASSOCIATION: (b2917)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_succoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mmcoa_R_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MNLpts" name="mannitol transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MNLpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: mnl[e] + pep[c] --&gt; mnl1p[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b3599#ABBREVIATION:mtlA#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, mannitol IIABC#ABBREVIATION:MtlA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2416) and (b3599)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mnl_e" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mnl1p_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MNNH" name="D-mannonate hydrolyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MNNH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.8</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : mana --&gt; 2ddglcn + h2o</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4322#ABBREVIATION:uxuA#ECNUMBERS:4.2.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:mannonate hydrolase#ABBREVIATION:UxuAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4322)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mana_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ddglcn_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MOAT" name="_3-deoxy-D-manno-octulosonic acid transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MOAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ckdo + lipidA --&gt; cmp + h + kdolipid4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 1043</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3633#ABBREVIATION:kdtA#ECNUMBERS:-2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-deoxy-d-manno-octulosonic acid transferase#ABBREVIATION:KdtA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3633)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ckdo_c" />
                    <speciesReference species="M_lipidA_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_kdolipid4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MOAT2" name="_3-deoxy-D-manno-octulosonic acid transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MOAT2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ckdo + kdolipid4 --&gt; cmp + h + kdo2lipid4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 1043</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3633#ABBREVIATION:kdtA#ECNUMBERS:-2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-deoxy-d-manno-octulosonic acid transferase#ABBREVIATION:KdtA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3633)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ckdo_c" />
                    <speciesReference species="M_kdolipid4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_kdo2lipid4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MOHMT" name="_3-methyl-2-oxobutanoate hydroxymethyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MOHMT</html:p>
                    <html:p>Synonyms: _6</html:p>
                    <html:p>EC Number: 2.1.2.11</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 3mob + h2o + mlthf --&gt; 2dhp + thf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0134#ABBREVIATION:panB#ECNUMBERS:2.1.2.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-methyl-2-oxobutanoate hydroxymethyltransferase#ABBREVIATION:PanB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0134)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3mob_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mlthf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dhp_c" />
                    <speciesReference species="M_thf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTAN" name="methylthioadenosine nucleosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MTAN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.2.16</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 5mta + h2o --&gt; 5mtr + ade</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0159#ABBREVIATION:pfs#ECNUMBERS:3.2.2.9,-!-,3.2.2.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Methylthioadenosine nucleosidase#ABBREVIATION:Mtn#</html:p>
                    <html:p>GENE ASSOCIATION: (b0159)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mta_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5mtr_c" />
                    <speciesReference species="M_ade_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTHFC" name="methenyltetrahydrofolate cyclohydrolase">
                <notes>
                    <html:p>Abbreviation: R_MTHFC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.9</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + methf &lt;==&gt; 10fthf</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0529#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0529)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_methf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_10fthf_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTHFD" name="methylenetetrahydrofolate dehydrogenase (NADP)">
                <notes>
                    <html:p>Abbreviation: R_MTHFD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.5.1.5</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : mlthf + nadp &lt;==&gt; h + methf + nadph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0529#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0529)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_mlthf_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_methf_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTHFR2" name="_5,10-methylenetetrahydrofolate reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MTHFR2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Folate Metabolism</html:p>
                    <html:p>Equation: [c] : h + mlthf + nadh --&gt; 5mthf + nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3941#ABBREVIATION:metF#ECNUMBERS:1.7.99.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Methylenetetrahydrofolate reductase#ABBREVIATION:MetF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3941)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mlthf_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5mthf_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTRI" name="_5-methylthioribose-1-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_MTRI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.23</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 5mdr1p &lt;==&gt; 5mdru1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mdr1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5mdru1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_MTRK" name="_5-methylthioribose kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_MTRK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.100</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 5mtr + atp --&gt; 5mdr1p + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5mtr_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5mdr1p_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NACODA" name="N-acetylornithine deacetylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NACODA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : acg5sa + h2o --&gt; ac + glu5sa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3957#ABBREVIATION:argE#ECNUMBERS:3.5.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetylornithine deacetylase#ABBREVIATION:ArgE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3957)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acg5sa_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_glu5sa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NACUP" name="Nicotinic acid uptake" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NACUP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: nac[e] --&gt; nac[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nac_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nac_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADDP" name="NAD diphosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADDP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.22</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + nad --&gt; amp + (2) h + nmn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>See also EC 3.6.1.9</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2411#ABBREVIATION:ligA#ECNUMBERS:6.5.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DNA ligase#ABBREVIATION:Lig#</html:p>
                    <html:p>GENE ASSOCIATION: (b2411)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nmn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADDPe" name="NAD diphosphatase (extracellular)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADDPe</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.22</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [e] : h2o + nad --&gt; amp + (2) h + nmn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_nad_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_e" />
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_nmn_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH10" name="NADH dehydrogenase (menaquinone-8 &amp; 0 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH10</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : h + mqn8 + nadh --&gt; mql8 + nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1109#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase II#ABBREVIATION:Ndh#</html:p>
                    <html:p>GENE ASSOCIATION: (b1109)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH5" name="NADH dehydrogenase (ubiquinone-8 )" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : h + nadh + q8 --&gt; nad + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added quinone specific reaction, q8</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1109#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase II#ABBREVIATION:Ndh#</html:p>
                    <html:p>GENE ASSOCIATION: (b1109)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH6" name="NADH dehydrogenase (ubiquinone-8 &amp; 3.5 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (4.5) h[c] + nadh[c] + q8[c] --&gt; (3.5) h[e] + nad[c] + q8h2[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2276#ABBREVIATION:nuoN#</html:p>
                    <html:p>LOCUS:b2277#ABBREVIATION:nuoM#</html:p>
                    <html:p>LOCUS:b2278#ABBREVIATION:nuoL#</html:p>
                    <html:p>LOCUS:b2279#ABBREVIATION:nuoK#</html:p>
                    <html:p>LOCUS:b2280#ABBREVIATION:nuoJ#</html:p>
                    <html:p>LOCUS:b2281#ABBREVIATION:nuoI#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2282#ABBREVIATION:nuoH#</html:p>
                    <html:p>LOCUS:b2283#ABBREVIATION:nuoG#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2284#ABBREVIATION:nuoF#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2285#ABBREVIATION:nuoE#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2286#ABBREVIATION:nuoC#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2287#ABBREVIATION:nuoB#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2288#ABBREVIATION:nuoA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase I#ABBREVIATION:Nuo#</html:p>
                    <html:p>GENE ASSOCIATION: (b2285 and b2284 and b2281 and b2287 and b2276 and b2283 and b2288 and b2282 and b2286 and b2277 and b2278 and b2280 and b2279)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="4.5" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="3.5" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH7" name="NADH dehydrogenase (menaquinone-8 &amp; 2 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (3) h[c] + mqn8[c] + nadh[c] --&gt; (2) h[e] + mql8[c] + nad[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2276#ABBREVIATION:nuoN#</html:p>
                    <html:p>LOCUS:b2277#ABBREVIATION:nuoM#</html:p>
                    <html:p>LOCUS:b2278#ABBREVIATION:nuoL#</html:p>
                    <html:p>LOCUS:b2279#ABBREVIATION:nuoK#</html:p>
                    <html:p>LOCUS:b2280#ABBREVIATION:nuoJ#</html:p>
                    <html:p>LOCUS:b2281#ABBREVIATION:nuoI#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2282#ABBREVIATION:nuoH#</html:p>
                    <html:p>LOCUS:b2283#ABBREVIATION:nuoG#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2284#ABBREVIATION:nuoF#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2285#ABBREVIATION:nuoE#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2286#ABBREVIATION:nuoC#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2287#ABBREVIATION:nuoB#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2288#ABBREVIATION:nuoA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase I#ABBREVIATION:Nuo#</html:p>
                    <html:p>GENE ASSOCIATION: (b2285 and b2284 and b2281 and b2287 and b2276 and b2283 and b2288 and b2282 and b2286 and b2277 and b2278 and b2280 and b2279)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH8" name="NADH dehydrogenase (demethylmenaquinone-8 &amp; 2.8 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH8</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: _2dmmq8[c] + (3.8) h[c] + nadh[c] --&gt; 2dmmql8[c] + (2.8) h[e] + nad[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2276#ABBREVIATION:nuoN#</html:p>
                    <html:p>LOCUS:b2277#ABBREVIATION:nuoM#</html:p>
                    <html:p>LOCUS:b2278#ABBREVIATION:nuoL#</html:p>
                    <html:p>LOCUS:b2279#ABBREVIATION:nuoK#</html:p>
                    <html:p>LOCUS:b2280#ABBREVIATION:nuoJ#</html:p>
                    <html:p>LOCUS:b2281#ABBREVIATION:nuoI#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2282#ABBREVIATION:nuoH#</html:p>
                    <html:p>LOCUS:b2283#ABBREVIATION:nuoG#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2284#ABBREVIATION:nuoF#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2285#ABBREVIATION:nuoE#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2286#ABBREVIATION:nuoC#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2287#ABBREVIATION:nuoB#ECNUMBERS:1.6.5.3#</html:p>
                    <html:p>LOCUS:b2288#ABBREVIATION:nuoA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase I#ABBREVIATION:Nuo#</html:p>
                    <html:p>GENE ASSOCIATION: (b2285 and b2284 and b2281 and b2287 and b2276 and b2283 and b2288 and b2282 and b2286 and b2277 and b2278 and b2280 and b2279)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_h_c" stoichiometry="3.8" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_h_e" stoichiometry="2.8" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADH9" name="NADH dehydrogenase (demethylmenaquinone-8 &amp; 0 protons)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADH9</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.6.5.3</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : 2dmmq8 + h + nadh --&gt; 2dmmql8 + nad</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1109#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NADH dehydrogenase II#ABBREVIATION:Ndh#</html:p>
                    <html:p>GENE ASSOCIATION: (b1109)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADK" name="NAD kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.23</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + nad --&gt; adp + h + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2615#ABBREVIATION:yfjB#ECNUMBERS:2.7.1.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NAD kinase#ABBREVIATION:YfjB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2615)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADPPPS" name="NADP phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADPPPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + nadp --&gt; nad + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADS1" name="NAD synthase (nh3)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.1.5</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + dnad + nh4 --&gt; amp + h + nad + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1740#ABBREVIATION:nadE#ECNUMBERS:6.3.5.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Deamido-NAD ammonia ligase or NAD synthetase#ABBREVIATION:NadEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1740)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dnad_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NADTRHD" name="NAD transhydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NADTRHD</html:p>
                    <html:p>Synonyms: _16</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : nad + nadph --&gt; nadh + nadp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>changed from TEST_NADTRHD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1602#ABBREVIATION:pntB#ECNUMBERS:1.6.1.2#</html:p>
                    <html:p>LOCUS:b1603#ABBREVIATION:pntA#ECNUMBERS:1.6.1.2#</html:p>
                    <html:p>LOCUS:b3962#ABBREVIATION:sthA#ECNUMBERS:1.6.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyridine nucleotide transhydrogenase#ABBREVIATION:Pnt#</html:p>
                    <html:p>NAME:Pyridine nucleotide transhydrogenase (soluble)#ABBREVIATION:SthA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1602 and b1603) or (b3962)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NAMNPP" name="nicotinic acid mononucleotide pyrophosphorylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NAMNPP</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.4.2.11</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + h2o + nac + prpp --&gt; adp + nicrnt + pi + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0931#ABBREVIATION:pncB#ECNUMBERS:2.4.2.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nicotinate phosphoribosyltransferase#ABBREVIATION:PncB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0931)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nac_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_nicrnt_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NAt3_1" name="sodium proton antiporter (H:NA is 1:1)">
                <notes>
                    <html:p>Abbreviation: R_NAt3_1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + na1[c] &lt;==&gt; h[c] + na1[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1216#ABBREVIATION:chaA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Sodium-calcium/proton antiporter#ABBREVIATION:ChaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1216)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_na1_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_na1_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NAt3_15" name="sodium proton antiporter (H:NA is 1.5)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NAt3_15</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (3) h[e] + (2) na1[c] --&gt; (3) h[c] + (2) na1[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1186#ABBREVIATION:nhaB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Na/H antiporter#ABBREVIATION:NhaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1186)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="3" />
                    <speciesReference species="M_na1_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_na1_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NAt3_2" name="sodium proton antiporter (H:NA is 2)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NAt3_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (2) h[e] + na1[c] --&gt; (2) h[c] + na1[e]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0019#ABBREVIATION:nhaA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Na+/H+ antiporter#ABBREVIATION:NhaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0019)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_na1_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_na1_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK1" name="nucleoside-diphosphate kinase (ATP:GDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + gdp &lt;==&gt; adp + gtp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gtp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK2" name="nucleoside-diphosphate kinase (ATP:UDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + udp &lt;==&gt; adp + utp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_udp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_utp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK3" name="nucleoside-diphosphate kinase (ATP:CDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + cdp &lt;==&gt; adp + ctp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_ctp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK4" name="nucleoside-diphosphate kinase (ATP:dTDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dtdp &lt;==&gt; adp + dttp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dtdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dttp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK5" name="nucleoside-diphosphate kinase (ATP:dGDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dgdp &lt;==&gt; adp + dgtp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dgdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dgtp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK6" name="nucleoside-diphosphate kinase (ATP:dUDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dudp &lt;==&gt; adp + dutp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dudp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dutp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK7" name="nucleoside-diphosphate kinase (ATP:dCDP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dcdp &lt;==&gt; adp + dctp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dcdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dctp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NDPK8" name="nucleoside-diphosphate kinase (ATP:dADP)">
                <notes>
                    <html:p>Abbreviation: R_NDPK8</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.6</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dadp &lt;==&gt; adp + datp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Many nucleoside diphosphates (eight described) can act as acceptors. 
While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2518#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2518)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_datp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NH4t" name="ammonia reversible transport">
                <notes>
                    <html:p>Abbreviation: R_NH4t</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: nh4[e] &lt;==&gt; nh4[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0451#ABBREVIATION:amtB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ammonium transporter#ABBREVIATION:AmtB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0451)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nh4_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NMNAT" name="nicotinamide-nucleotide adenylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NMNAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + h + nmn --&gt; nad + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0639#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0639)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nmn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NMNDA" name="nicotinamide-nucleotide amidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NMNDA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.42</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + nmn --&gt; nh4 + nicrnt</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nmn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_nicrnt_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NMNN" name="NMN nucleosidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NMNN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.2.14</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + nmn --&gt; h + ncam + r5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nmn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ncam_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NMNP" name="NMN permease" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NMNP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: nmn[e] --&gt; nmn[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0751#ABBREVIATION:pnuC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NMN permease#ABBREVIATION:PnuCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0751)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nmn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nmn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NMNt7" name="NMN transport via NMN glycohydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NMNt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.2.14</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h2o[c] + nmn[e] --&gt; h[c] + ncam[c] + r5p[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nmn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ncam_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NNAM" name="nicotinamidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NNAM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.19</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + ncam --&gt; nac + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1768#ABBREVIATION:pncA#ECNUMBERS:3.5.1.19,-!-,3.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:NCAM amidohydrolase#ABBREVIATION:PncA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1768)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ncam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nac_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NNAT" name="nicotinate-nucleotide adenylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NNAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.18</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + h + nicrnt --&gt; dnad + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0639#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0639)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nicrnt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dnad_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NNDMBRT" name="Nicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NNDMBRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dmbzid + nicrnt --&gt; 5prdmbz + h + nac</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (Kegg R04148)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1991#ABBREVIATION:cobT#ECNUMBERS:2.4.2.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nicotinate-nucleotide dimethylbenzimidazole-P phosphoribosyl transferase#ABBREVIATION:CobT#</html:p>
                    <html:p>GENE ASSOCIATION: (b1991)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmbzid_c" />
                    <speciesReference species="M_nicrnt_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5prdmbz_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nac_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NNDPR" name="nicotinate-nucleotide diphosphorylase (carboxylating)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NNDPR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.19</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (2) h + prpp + quln --&gt; co2 + nicrnt + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0109#ABBREVIATION:nadC#ECNUMBERS:2.4.2.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:quinolate phosphoribosyl transferase#ABBREVIATION:NadCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0109)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_prpp_c" />
                    <speciesReference species="M_quln_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nicrnt_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NO2t2r" name="nitrite transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_NO2t2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + no2[e] &lt;==&gt; h[c] + no2[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1223#ABBREVIATION:narK#</html:p>
                    <html:p>LOCUS:b3367#ABBREVIATION:nirC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS Nitrite, Nitrate transporter#ABBREVIATION:NarKec#</html:p>
                    <html:p>NAME:FNT, nitrite transporter#ABBREVIATION:NirC#</html:p>
                    <html:p>GENE ASSOCIATION: (b1223) or (b3367)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_no2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_no2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NO3R1" name="Nitrate reductase (Ubiquinol-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NO3R1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.7.99.4</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[c] + no3[c] + q8h2[c] --&gt; (2) h[e] + h2o[c] + no2[c] + q8[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (assumed h2o is by-product)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1224#ABBREVIATION:narG#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1225#ABBREVIATION:narH#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1226#ABBREVIATION:narJ#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1227#ABBREVIATION:narI#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nitrate reductase I#ABBREVIATION:NarGHIJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b1225 and b1226 and b1224 and b1227)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_no3_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_no2_c" />
                    <speciesReference species="M_q8_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NO3R2" name="Nitrate reductase (Menaquinol-8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NO3R2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[c] + mql8[c] + no3[c] --&gt; (2) h[e] + h2o[c] + mqn8[c] + no2[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (assumed h2o is by-product)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1224#ABBREVIATION:narG#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1225#ABBREVIATION:narH#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1226#ABBREVIATION:narJ#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>LOCUS:b1227#ABBREVIATION:narI#ECNUMBERS:1.7.99.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nitrate reductase I#ABBREVIATION:NarGHIJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b1225 and b1226 and b1224 and b1227)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_no3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_no2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NO3t7" name="nitrate transport in via nitrite antiport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NO3t7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: no2[c] + no3[e] --&gt; no2[e] + no3[c]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1469#ABBREVIATION:narU#</html:p>
                    <html:p>LOCUS:b1223#ABBREVIATION:narK#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS Nitrite, Nitrate transporter#ABBREVIATION:NarKec#</html:p>
                    <html:p>NAME:MFS, nitrite extrusion and nitrate uptake transport#ABBREVIATION:NarU#</html:p>
                    <html:p>GENE ASSOCIATION: (b1223) or (b1469)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_no2_c" />
                    <speciesReference species="M_no3_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_no2_e" />
                    <speciesReference species="M_no3_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NPHS" name="naphthoate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NPHS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.3.36</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : sbzcoa --&gt; coa + dhna</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2262#ABBREVIATION:menB#ECNUMBERS:4.1.3.36#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Napthoate synthase#ABBREVIATION:MenB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2262)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_sbzcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_dhna_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD1" name="_5'-nucleotidase (dUMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dump + h2o --&gt; duri + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dump_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_duri_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD10" name="_5'-nucleotidase (XMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD10</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : h2o + xmp --&gt; pi + xtsn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_xmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_xtsn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD11" name="_5'-nucleotidase (IMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD11</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : h2o + imp --&gt; ins + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_imp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ins_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD2" name="_5'-nucleotidase (UMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : h2o + ump --&gt; pi + uri</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ump_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_uri_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD3" name="_5'-nucleotidase (dCMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dcmp + h2o --&gt; dcyt + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dcmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcyt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD4" name="_5'-nucleotidase (CMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : cmp + h2o --&gt; cytd + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cytd_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD5" name="_5'-nucleotidase (dTMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dtmp + h2o --&gt; pi + thymd</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_thymd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD6" name="_5'-nucleotidase (dAMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : damp + h2o --&gt; dad-2 + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_damp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dad_2_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD7" name="_5'-nucleotidase (AMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : amp + h2o --&gt; adn + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD8" name="_5'-nucleotidase (dGMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD8</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dgmp + h2o --&gt; dgsn + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgsn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTD9" name="_5'-nucleotidase (GMP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTD9</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.5</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gmp + h2o --&gt; gsn + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Wide specificity for 5&amp;apos;-nucleotides
Also see EC 3.1.3.31</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gsn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP1" name="Nucleoside triphosphate pyrophosphorylase (dgtp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dgtp + h2o --&gt; dgmp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0099#ABBREVIATION:mutT#ECNUMBERS:3.6.1.-#</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleoside triphosphatase#ABBREVIATION:MutT#</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b0099) or (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgtp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP2" name="Nucleoside triphosphate pyrophosphorylase (gtp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gtp + h2o --&gt; gmp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0099#ABBREVIATION:mutT#ECNUMBERS:3.6.1.-#</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleoside triphosphatase#ABBREVIATION:MutT#</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781) or (b0099)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP3" name="Nucleoside triphosphate pyrophosphorylase (dctp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dctp + h2o --&gt; dcmp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dctp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP4" name="Nucleoside triphosphate pyrophosphorylase (ctp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ctp + h2o --&gt; cmp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP5" name="Nucleoside triphosphate pyrophosphorylase (datp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : datp + h2o --&gt; damp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_datp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_damp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP6" name="Nucleoside triphosphate pyrophosphorylase (atp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + h2o --&gt; amp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP7" name="Nucleoside triphosphate pyrophosphorylase (dttp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dttp + h2o --&gt; dtmp + h + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dttp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPP8" name="Nucleoside triphosphate pyrophosphorylase (utp)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPP8</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : h2o + utp --&gt; h + ppi + ump</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2781#ABBREVIATION:mazG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2781)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_utp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPTP1" name="Nucleoside triphosphate tripolyhydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPTP1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.5.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dgtp + h2o --&gt; dgsn + pppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0160#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Deoxyguanosine triphosphate triphosphohydrolase#ABBREVIATION:Dgt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0160)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgtp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgsn_c" />
                    <speciesReference species="M_pppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTPTP2" name="Nucleoside triphosphate tripolyhydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTPTP2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.5.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gtp + h2o --&gt; gsn + pppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0160#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Deoxyguanosine triphosphate triphosphohydrolase#ABBREVIATION:Dgt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0160)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gsn_c" />
                    <speciesReference species="M_pppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_NTRIR2x" name="nitrite Reductase (NADH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_NTRIR2x</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : (5) h + (3) nadh + no2 --&gt; (2) h2o + (3) nad + nh4</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (assumed hydroxide anion and h come together to make water, EC 1.7.1.4)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3365#ABBREVIATION:nirB#ECNUMBERS:1.7.1.4#</html:p>
                    <html:p>LOCUS:b3366#ABBREVIATION:nirD#ECNUMBERS:1.7.1.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:nitrite reductase#ABBREVIATION:NirBD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3365 and b3366)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="5" />
                    <speciesReference species="M_nadh_c" stoichiometry="3" />
                    <speciesReference species="M_no2_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_nad_c" stoichiometry="3" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_O2t" name="o2 transport (diffusion)">
                <notes>
                    <html:p>Abbreviation: R_O2t</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: o2[e] &lt;==&gt; o2[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
renamed from O2TP to O2t to avoid confusion with transport reaction from cytosol to peroxisome
NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_o2_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_o2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OBTFL" name="_2-Oxobutanoate formate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OBTFL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2obut + coa --&gt; for + ppcoa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0902#ABBREVIATION:pflA#ECNUMBERS:1.97.1.4#</html:p>
                    <html:p>LOCUS:b0903#ABBREVIATION:pflB#ECNUMBERS:2.3.1.54#</html:p>
                    <html:p>LOCUS:b3114#ABBREVIATION:tdcE#ECNUMBERS:2.3.1.54#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyruvate formate lyase I#ABBREVIATION:PflA#</html:p>
                    <html:p>NAME:pyruvate formate-lyase and 2-ketobuytrate formate-lyase#ABBREVIATION:TdcE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3114) or (b0902 and b0903)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2obut_c" />
                    <speciesReference species="M_coa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_for_c" />
                    <speciesReference species="M_ppcoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OCBT" name="ornithine carbamoyltransferase">
                <notes>
                    <html:p>Abbreviation: R_OCBT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.1.3.3</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : cbp + orn &lt;==&gt; citr-L + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0273#ABBREVIATION:argF#ECNUMBERS:2.1.3.3#</html:p>
                    <html:p>LOCUS:b4254#ABBREVIATION:argI#ECNUMBERS:2.1.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ornithine carbamoyl transferase II#ABBREVIATION:ArgF#</html:p>
                    <html:p>NAME:Ornithine carbamoyltransferase I#ABBREVIATION:ArgI#</html:p>
                    <html:p>GENE ASSOCIATION: (b4254) or (b0273)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cbp_c" />
                    <speciesReference species="M_orn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_citr_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OCDCAt2" name="Octadecanoate transport via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OCDCAt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ocdca[e] --&gt; h[c] + ocdca[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2344#ABBREVIATION:fadL#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:long chain fatty acid transporter#ABBREVIATION:FadL#</html:p>
                    <html:p>GENE ASSOCIATION: (b2344)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ocdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ocdca_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OCTDPS" name="Octaprenyl pyrophosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OCTDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : frdp + (5) ipdp --&gt; octdp + (5) ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
JLR- EC 2.5.1.-</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3187#ABBREVIATION:ispB#ECNUMBERS:2.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Octaprenyl-diphosphate synthase#ABBREVIATION:IspB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3187)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_frdp_c" />
                    <speciesReference species="M_ipdp_c" stoichiometry="5" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_octdp_c" />
                    <speciesReference species="M_ppi_c" stoichiometry="5" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OHPBAT" name="O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase">
                <notes>
                    <html:p>Abbreviation: R_OHPBAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.52</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : glu-L + ohpb &lt;==&gt; akg + phthr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0907#ABBREVIATION:serC#ECNUMBERS:2.6.1.52#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0907)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_ohpb_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_phthr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OHPHM" name="_2-octaprenyl-6-hydroxyphenol methylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OHPHM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2ohph + amet --&gt; 2omph + ahcys + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- not sure about enzyme name (EC- 2.1.1.-)
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2232#ABBREVIATION:ubiG#ECNUMBERS:2.1.1.64#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-demethylubiquinone-9 3-methytransferase and 2-octaprenyl-6-hydroxyphenol methylase#ABBREVIATION:UbiG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2232)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ohph_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2omph_c" />
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OMBZLM" name="_2-Octaprenyl-6-methoxy-benzoquinol methylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OMBZLM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2ombzl + amet --&gt; 2ommbl + ahcys + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3833#ABBREVIATION:ubiE#ECNUMBERS:2.1.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinonol methylase#ABBREVIATION:UbiE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3833)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ombzl_c" />
                    <speciesReference species="M_amet_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ommbl_c" />
                    <speciesReference species="M_ahcys_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OMCDC" name="_2-Oxo-4-methyl-3-carboxypentanoate decarboxylation" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OMCDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : 3c4mop + h --&gt; 4mop + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Continuation of EC 1.1.1.85 reaction</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0073#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0073)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3c4mop_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4mop_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OMMBLHX" name="_2-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OMMBLHX</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2ommbl + (0.5) o2 --&gt; 2omhmbl</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- not sure about the reaction</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0662#ABBREVIATION:ubiF#ECNUMBERS:1.14.13.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-Octaprenyl3-methyl-6-methoxy-1,4-benzoquinol hydroxylase#ABBREVIATION:UbiF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0662)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2ommbl_c" />
                    <speciesReference species="M_o2_c" stoichiometry="0.5" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2omhmbl_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OMPDC" name="orotidine-5'-phosphate decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OMPDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.23</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : h + orot5p --&gt; co2 + ump</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1281#ABBREVIATION:pyrF#ECNUMBERS:4.1.1.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Orotidine 5'-phosphate decarboxylase#ABBREVIATION:PyrF#</html:p>
                    <html:p>GENE ASSOCIATION: (b1281)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_orot5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OMPHHX" name="_2-octaprenyl-6-methoxyphenol hydroxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OMPHHX</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2omph + (0.5) o2 --&gt; 2ombzl</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- not sure about the reaction (EC 1.14.3.-)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2907#ABBREVIATION:ubiH#ECNUMBERS:1.14.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-octaprenyl-6-methoxyphenol hydroxylase#ABBREVIATION:UbiH#</html:p>
                    <html:p>GENE ASSOCIATION: (b2907)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2omph_c" />
                    <speciesReference species="M_o2_c" stoichiometry="0.5" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ombzl_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OP4ENH" name="_2-oxopent-4-enoate hydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OP4ENH</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.2.1.80</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + op4en --&gt; 4h2opntn</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0350#ABBREVIATION:mhpD#ECNUMBERS:4.2.1.80#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-keto-4-pentenoate hydratase#ABBREVIATION:MhpD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0350)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_op4en_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4h2opntn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OPHBDC" name="Octaprenyl-hydroxybenzoate decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OPHBDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 3ophb + h --&gt; 2oph + co2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR (EC - 4.1.1.-)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2311#ABBREVIATION:ubiX#ECNUMBERS:4.1.1.-#</html:p>
                    <html:p>LOCUS:b3843#ABBREVIATION:ubiD#ECNUMBERS:4.1.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:octaprenyl-hydroxybenzoate decarboxylase#ABBREVIATION:UbiD#</html:p>
                    <html:p>NAME:Octaprenyl4-hydroxybenzoate decarboxylase II#ABBREVIATION:UbiX#</html:p>
                    <html:p>GENE ASSOCIATION: (b3843) or (b2311)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3ophb_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2oph_c" />
                    <speciesReference species="M_co2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OPHHX" name="_2-Octaprenylphenol hydroxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OPHHX</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2oph + (0.5) o2 --&gt; 2ohph</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- not sure about this reaction (EC 1.13.14.-)
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3835#ABBREVIATION:ubiB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_2-octaprenylphenol hydroxylase#ABBREVIATION:UbiB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3835)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2oph_c" />
                    <speciesReference species="M_o2_c" stoichiometry="0.5" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2ohph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ORNDC" name="Ornithine Decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ORNDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.17</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : h + orn --&gt; co2 + ptrc</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added proton to balance</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0693#ABBREVIATION:speF#ECNUMBERS:4.1.1.17#</html:p>
                    <html:p>LOCUS:b2965#ABBREVIATION:speC#ECNUMBERS:4.1.1.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ornithine decarboxylase#ABBREVIATION:SpeC#</html:p>
                    <html:p>NAME:ornithine decarboxylase#ABBREVIATION:SpeF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2965) or (b0693)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_orn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_ptrc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ORNTA" name="ornithine transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ORNTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.13</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : akg + orn --&gt; glu-L + glu5sa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3073#ABBREVIATION:ygjG#ECNUMBERS:2.6.1.29#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:acetylornithine aminotrasferase#ABBREVIATION:YgjG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3073)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_orn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_glu5sa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ORNabc" name="ornithine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_ORNabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + orn[e] --&gt; adp[c] + h[c] + orn[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2306#ABBREVIATION:hisP#</html:p>
                    <html:p>LOCUS:b2307#ABBREVIATION:hisM#</html:p>
                    <html:p>LOCUS:b2308#ABBREVIATION:hisQ#</html:p>
                    <html:p>LOCUS:b2310#ABBREVIATION:argT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, lys/arg/ornithine (periplasm)#ABBREVIATION:ArgT#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/orn (membrane)#ABBREVIATION:HisM#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (atp)#ABBREVIATION:HisP#</html:p>
                    <html:p>NAME:ABC, his and lys/arg/ornithine (membrane)#ABBREVIATION:HisQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2310) and (b2308) and (b2307) and (b2306)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_orn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_orn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_ORPT" name="orotate phosphoribosyltransferase">
                <notes>
                    <html:p>Abbreviation: R_ORPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.10</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : orot5p + ppi &lt;==&gt; orot + prpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3642#ABBREVIATION:pyrE#ECNUMBERS:2.4.2.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Orotate phosphoribosyltransferase#ABBREVIATION:PyrE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3642)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_orot5p_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_orot_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_OXGDC2" name="_2-oxoglutarate decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_OXGDC2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.1.1.71</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : akg + h + thmpp --&gt; co2 + ssaltpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2264#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.5.1.64#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:a-ketoglutarate decarboxylase and SHCHC cynthase#ABBREVIATION:MenD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2264)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thmpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_ssaltpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_P5CD" name="_1-pyrroline-5-carboxylate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_P5CD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.5.1.12</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 1pyr5c + (2) h2o + nad --&gt; glu-L + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Oxidizes other 1-pyrrolines, e.g. 3-hydroxy-1-pyrroline-5-carboxylate forms 4-hydroxyglutamate</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1014#ABBREVIATION:putA#ECNUMBERS:1.5.99.8,-!-,1.5.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Proline dehydrogenase and Pyrroline-5-carboxylate dehydrogenase#ABBREVIATION:PutAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1014)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_1pyr5c_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_P5CR" name="pyrroline-5-carboxylate reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_P5CR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.5.1.2</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 1pyr5c + (2) h + nadph --&gt; nadp + pro-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0386#ABBREVIATION:proC#ECNUMBERS:1.5.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Pyrroline-5-carboxylate reductase#ABBREVIATION:ProC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0386)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_1pyr5c_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_pro_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PACCOAL" name="phenylacetate-CoA ligase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PACCOAL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.2.1.30</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + coa + pac --&gt; amp + phaccoa + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1398#ABBREVIATION:paaK#ECNUMBERS:6.2.1.30#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phenylacetyl-CoA ligase#ABBREVIATION:PaaK#</html:p>
                    <html:p>GENE ASSOCIATION: (b1398)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_pac_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_phaccoa_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PANTS" name="pantothenate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PANTS</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 6.3.2.1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ala-B + atp + pant-R --&gt; amp + h + pnto-R + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0133#ABBREVIATION:panC#ECNUMBERS:6.3.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Pantoate-b-alanine ligase#ABBREVIATION:PanCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0133)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_B_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pant_R_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pnto_R_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PAPA_EC" name="Phosphatidate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PAPA_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.4</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (0.02) pa_EC --&gt; (0.02) 12dgr_EC + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pa_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_12dgr_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PAPPT3" name="phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PAPPT3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.8.13</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : udcpp + ugmda --&gt; uagmda + ump</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0087#ABBREVIATION:mraY#ECNUMBERS:2.7.8.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phospho-N-acetylmuramoyl-pentapeptide transferase#ABBREVIATION:MraY#</html:p>
                    <html:p>GENE ASSOCIATION: (b0087)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_udcpp_c" />
                    <speciesReference species="M_ugmda_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_uagmda_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PAPSR" name="phosphoadenylyl-sulfate reductase (thioredoxin)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PAPSR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.8.4.8</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : paps + trdrd --&gt; (2) h + pap + so3 + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previous EC 1.8.99.4. Now EC 1.8.4.8</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2762#ABBREVIATION:cysH#ECNUMBERS:1.8.4.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3'-phosphoadenosine 5'-phosphosulfate reductase#ABBREVIATION:CysH#</html:p>
                    <html:p>GENE ASSOCIATION: (b2762)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_paps_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pap_c" />
                    <speciesReference species="M_so3_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PASYN_EC" name="Phosphatidic acid synthase (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PASYN_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --&gt; (2) ACP + (0.02) pa_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3018#ABBREVIATION:plsC#ECNUMBERS:2.3.1.51#</html:p>
                    <html:p>LOCUS:b4041#ABBREVIATION:plsB#ECNUMBERS:2.3.1.15#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_1-acyl-glycerol-3-phosphate acyltransferase#ABBREVIATION:PlsC#</html:p>
                    <html:p>NAME:glycerolphosphate acyltransferase#ABBREVIATION:PlsBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3018) and (b4041)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_glyc3p_c" />
                    <speciesReference species="M_hdeACP_c" stoichiometry="0.14" />
                    <speciesReference species="M_myrsACP_c" stoichiometry="0.04" />
                    <speciesReference species="M_octeACP_c" />
                    <speciesReference species="M_palmACP_c" stoichiometry="0.72" />
                    <speciesReference species="M_tdeACP_c" stoichiometry="0.1" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" stoichiometry="2" />
                    <speciesReference species="M_pa_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PDH" name="pyruvate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : coa + nad + pyr --&gt; accoa + co2 + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0114#ABBREVIATION:aceE#ECNUMBERS:1.2.4.1#</html:p>
                    <html:p>LOCUS:b0115#ABBREVIATION:aceF#ECNUMBERS:2.3.1.12#</html:p>
                    <html:p>LOCUS:b0116#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA#</html:p>
                    <html:p>NAME:Pyruvate Dehdrogenase, E#ABBREVIATION:AceEec#</html:p>
                    <html:p>NAME:Pyruvate dehydrogenase, F#ABBREVIATION:AceFec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0114) and (b0116) and (b0115)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PDX5PO" name="pyridoxine 5'-phosphate oxidase">
                <notes>
                    <html:p>Abbreviation: R_PDX5PO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.3.5</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : o2 + pdx5p &lt;==&gt; h2o2 + pydx5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1638#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1638)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_o2_c" />
                    <speciesReference species="M_pdx5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o2_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PDX5PS" name="Pyridoxine 5'-phosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PDX5PS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dxyl5p + nad + phthr --&gt; co2 + h + (2) h2o + nadh + pdx5p + pi</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR- two reactions combined (intermediate of the first is unknown)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0052#ABBREVIATION:pdxA#ECNUMBERS:1.1.1.262#</html:p>
                    <html:p>LOCUS:b2564#ABBREVIATION:pdxJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Pyridoxine 5-phosphate biosynthetic protein#ABBREVIATION:PdxAJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2564 and b0052)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dxyl5p_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_phthr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_pdx5p_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PDXPP" name="Pyridoxine 5-phosphate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PDXPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + pdx5p --&gt; pi + pydxn</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pdx5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_pydxn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PEAMNO" name="Phenethylamine oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PEAMNO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.3.6</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + o2 + peamn --&gt; h2o2 + nh4 + pacald</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- Kegg reaction R02613</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1386#ABBREVIATION:tynA#ECNUMBERS:1.4.3.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tyramine oxidase#ABBREVIATION:TynA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1386)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_o2_c" />
                    <speciesReference species="M_peamn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o2_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pacald_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PEPT_EC" name="ethanolamine phosphotransferase">
                <notes>
                    <html:p>Abbreviation: R_PEPT_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.8.1</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : cmp + h + (0.02) pe_EC &lt;==&gt; (0.02) 12dgr_EC + cdpea</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pe_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_12dgr_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_cdpea_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PERD" name="Erythronate 4-phosphate (4per) dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_PERD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4per + nad &lt;==&gt; h + nadh + ohpb</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2320#ABBREVIATION:pdxB#ECNUMBERS:1.1.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:erythronate-4-phosphate dehydrogenase#ABBREVIATION:PdxB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2320)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4per_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_ohpb_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PFK" name="phosphofructokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PFK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.11</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : atp + f6p --&gt; adp + fdp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1723#ABBREVIATION:pfkB#ECNUMBERS:2.7.1.11#</html:p>
                    <html:p>LOCUS:b3916#ABBREVIATION:pfkA#ECNUMBERS:2.7.1.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphofructokinase#ABBREVIATION:PfkA#</html:p>
                    <html:p>NAME:Phosphofructokinase II#ABBREVIATION:PfkB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3916) or (b1723)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_f6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fdp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PFK_2" name="Phosphofructokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PFK_2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.7.1.11</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + tag6p-D --&gt; adp + h + tagdp-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Also EC 2.7.1.144
JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1723#ABBREVIATION:pfkB#ECNUMBERS:2.7.1.11#</html:p>
                    <html:p>LOCUS:b2168#ABBREVIATION:fruK#ECNUMBERS:2.7.1.56#</html:p>
                    <html:p>LOCUS:b3132#ABBREVIATION:kbaZ#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>LOCUS:b3137#ABBREVIATION:kbaY#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphofructokinase II#ABBREVIATION:PfkB#</html:p>
                    <html:p>NAME:_1-phosphofructokinase#ABBREVIATION:FruK#</html:p>
                    <html:p>NAME:tagatose 6-phosphate aldolase I#ABBREVIATION:AgaZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2168) or (b1723) or (b3137 and b3132)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_tag6p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_tagdp_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PFL" name="pyruvate formate lyase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PFL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : coa + pyr --&gt; accoa + for</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR
E.C. - 2.3.1.54  MM

</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0902#ABBREVIATION:pflA#ECNUMBERS:1.97.1.4#</html:p>
                    <html:p>LOCUS:b0903#ABBREVIATION:pflB#ECNUMBERS:2.3.1.54#</html:p>
                    <html:p>LOCUS:b3114#ABBREVIATION:tdcE#ECNUMBERS:2.3.1.54#</html:p>
                    <html:p>LOCUS:b3951#ABBREVIATION:pflD#</html:p>
                    <html:p>LOCUS:b3952#ABBREVIATION:pflC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyruvate formate lyase I#ABBREVIATION:PflA#</html:p>
                    <html:p>NAME:pyruvate formate lyase II#ABBREVIATION:PflC#</html:p>
                    <html:p>NAME:pyruvate formate-lyase and 2-ketobuytrate formate-lyase#ABBREVIATION:TdcE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3951 and b3952) or (b0902 and b0903) or (b3114)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_for_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGAMT" name="phosphoglucosamine mutase">
                <notes>
                    <html:p>Abbreviation: R_PGAMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.10</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : gam1p &lt;==&gt; gam6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis. </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3176#ABBREVIATION:glmM#ECNUMBERS:5.4.2.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoglucosamine mutase#ABBREVIATION:MrsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3176)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gam1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gam6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGCD" name="phosphoglycerate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PGCD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.95</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : 3pg + nad --&gt; 3php + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2913#ABBREVIATION:serA#ECNUMBERS:1.1.1.95#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoglycerate dehydrogenase#ABBREVIATION:SerA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2913)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3pg_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3php_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGI" name="glucose-6-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_PGI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.9</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : g6p &lt;==&gt; f6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4025#ABBREVIATION:pgi#ECNUMBERS:5.3.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucose-6-phosphate isomerase#ABBREVIATION:Pgi#</html:p>
                    <html:p>GENE ASSOCIATION: (b4025)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGK" name="phosphoglycerate kinase">
                <notes>
                    <html:p>Abbreviation: R_PGK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.3</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : 3pg + atp &lt;==&gt; 13dpg + adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2926#ABBREVIATION:pgk#ECNUMBERS:2.7.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoglycerate kinase#ABBREVIATION:Pgk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2926)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3pg_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_13dpg_c" />
                    <speciesReference species="M_adp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGL" name="_6-phosphogluconolactonase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PGL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.1.31</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : 6pgl + h2o --&gt; 6pgc + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP 
Net reaction same as described in Lehringer 334</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_6pgl_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_6pgc_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGLYCP" name="Phosphoglycolate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PGLYCP</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 3.1.3.18</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2pglyc + h2o --&gt; glyclt + pi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3385#ABBREVIATION:gph#ECNUMBERS:3.1.3.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoglycolate phosphatase#ABBREVIATION:Gph#</html:p>
                    <html:p>GENE ASSOCIATION: (b3385)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2pglyc_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyclt_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGM" name="phosphoglycerate mutase">
                <notes>
                    <html:p>Abbreviation: R_PGM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : 2pg &lt;==&gt; 3pg</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0755#ABBREVIATION:gpmA#ECNUMBERS:5.4.2.1#</html:p>
                    <html:p>LOCUS:b3612#ABBREVIATION:gpmI#ECNUMBERS:5.4.2.1#</html:p>
                    <html:p>LOCUS:b4395#ABBREVIATION:ytjC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoglycerate mutase II#ABBREVIATION:GpmB#</html:p>
                    <html:p>NAME:phosphoglycerate mutase I#ABBREVIATION:GpmA#</html:p>
                    <html:p>NAME:phosphoglycerate mutase III#ABBREVIATION:YibO#</html:p>
                    <html:p>GENE ASSOCIATION: (b0755) or (b4395) or (b3612)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2pg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3pg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGMT" name="phosphoglucomutase">
                <notes>
                    <html:p>Abbreviation: R_PGMT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.2</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : g1p &lt;==&gt; g6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0688#ABBREVIATION:pgm#ECNUMBERS:5.4.2.2#</html:p>
                    <html:p>LOCUS:b2690#ABBREVIATION:yqaB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoglucomutase#ABBREVIATION:Pgmec#</html:p>
                    <html:p>NAME:putative phosphoglucomutase#ABBREVIATION:YqaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0688) or (b2690)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGPP_EC" name="Phosphatidylglycerol phosphate phosphatase (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PGPP_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.27</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + (0.02) pgp_EC --&gt; (0.02) pg_EC + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0418#ABBREVIATION:pgpA#ECNUMBERS:3.1.3.27#</html:p>
                    <html:p>LOCUS:b1278#ABBREVIATION:pgpB#ECNUMBERS:3.1.3.27#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphatidylglycerol phosphate phosphatase A#ABBREVIATION:PgpAec#</html:p>
                    <html:p>NAME:Phosphatidylglycerol phosphate phosphatase B#ABBREVIATION:PgpBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0418) or (b1278)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pgp_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PGSA_EC" name="Phosphatidylglycerol synthase (Ecoli)">
                <notes>
                    <html:p>Abbreviation: R_PGSA_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.8.5</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : (0.02) cdpdag_EC + glyc3p &lt;==&gt; cmp + h + (0.02) pgp_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1912#ABBREVIATION:pgsA#ECNUMBERS:2.7.8.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphatidylglycerophosphate synthase#ABBREVIATION:PgsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1912)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_glyc3p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pgp_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PHETA1" name="phenylalanine transaminase">
                <notes>
                    <html:p>Abbreviation: R_PHETA1</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 2.6.1.58</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : akg + phe-L &lt;==&gt; glu-L + phpyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0928#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1#</html:p>
                    <html:p>LOCUS:b3770#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42#</html:p>
                    <html:p>LOCUS:b4054#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE#</html:p>
                    <html:p>NAME:aspartate aminotransferase#ABBREVIATION:AspC#</html:p>
                    <html:p>NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3770) or (b4054) or (b0928)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_phe_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_phpyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PHEt2r" name="L-phenylalanine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_PHEt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + phe-L[e] &lt;==&gt; h[c] + phe-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0112#ABBREVIATION:aroP#</html:p>
                    <html:p>LOCUS:b0576#ABBREVIATION:pheP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, aromatic AA proton symporter#ABBREVIATION:AroP#</html:p>
                    <html:p>NAME:APC, phenylalanine H symport#ABBREVIATION:PheP#</html:p>
                    <html:p>GENE ASSOCIATION: (b0112) or (b0576)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_phe_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_phe_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PIabc" name="phosphate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PIabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + pi[e] --&gt; adp[c] + h[c] + (2) pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3725#ABBREVIATION:pstB#ECNUMBERS:3.6.3.27#</html:p>
                    <html:p>LOCUS:b3726#ABBREVIATION:pstA#</html:p>
                    <html:p>LOCUS:b3727#ABBREVIATION:pstC#</html:p>
                    <html:p>LOCUS:b3728#ABBREVIATION:pstS#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, phosphate transporter (membrane)#ABBREVIATION:PstA#</html:p>
                    <html:p>NAME:ABC, phosphate transporter (atp)#ABBREVIATION:PstB#</html:p>
                    <html:p>NAME:ABC, phosphate transporter (membrane)#ABBREVIATION:PstC#</html:p>
                    <html:p>NAME:ABC, phosphate transporter (periplasm)#ABBREVIATION:PstD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3725) and (b3727) and (b3726) and (b3728)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pi_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PIt2r" name="phosphate reversible transport via symport">
                <notes>
                    <html:p>Abbreviation: R_PIt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + pi[e] &lt;==&gt; h[c] + pi[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2987#ABBREVIATION:pitB#</html:p>
                    <html:p>LOCUS:b3493#ABBREVIATION:pitA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphate H symporter#ABBREVIATION:PitA#</html:p>
                    <html:p>NAME:Phosphate H symporter#ABBREVIATION:PitBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3493) or (b2987)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_pi_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PLIPA1" name="Phospholipase A (phosphatidylglycerol)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PLIPA1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (0.02) pg_EC --&gt; (0.02) agpg_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3821#ABBREVIATION:pldA#ECNUMBERS:3.1.1.32#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phospholipase A#ABBREVIATION:PldA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3821)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pg_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_agpg_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PLIPA2" name="Phosphlipase A (phosphatidylethanolamine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PLIPA2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (0.02) pe_EC --&gt; (0.02) agpe_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3821#ABBREVIATION:pldA#ECNUMBERS:3.1.1.32#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phospholipase A#ABBREVIATION:PldA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3821)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pe_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_agpe_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PLIPA3" name="Phospholipase A (phosphatidylcholine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PLIPA3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (0.02) pc_EC --&gt; (0.02) agpc_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3821#ABBREVIATION:pldA#ECNUMBERS:3.1.1.32#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phospholipase A#ABBREVIATION:PldA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3821)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pc_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_agpc_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_hdca_c" stoichiometry="0.36" />
                    <speciesReference species="M_hdcea_c" stoichiometry="0.07" />
                    <speciesReference species="M_ocdcea_c" stoichiometry="0.5" />
                    <speciesReference species="M_ttdca_c" stoichiometry="0.02" />
                    <speciesReference species="M_ttdcea_c" stoichiometry="0.05" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PMANM" name="phosphomannomutase">
                <notes>
                    <html:p>Abbreviation: R_PMANM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.8</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : man1p &lt;==&gt; man6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2048#ABBREVIATION:cpsG#ECNUMBERS:5.4.2.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphomannomutase#ABBREVIATION:CpsG#</html:p>
                    <html:p>GENE ASSOCIATION: (b2048)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_man1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_man6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PMDPHT" name="pyrimidine phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PMDPHT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 5aprbu + h2o --&gt; 4r5au + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5aprbu_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4r5au_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PMPK" name="phosphomethylpyrimidine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PMPK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.7</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4ampm + atp --&gt; 2mahmp + adp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2103#ABBREVIATION:thiD#ECNUMBERS:2.7.4.7,-!-,2.7.1.49#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:hydroxy-phosphomethylpyrimidine kinase and hydroxy-methylpyrimidine kinase#ABBREVIATION:ThiDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2103)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4ampm_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2mahmp_c" />
                    <speciesReference species="M_adp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PNTK" name="pantothenate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PNTK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.33</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + pnto-R --&gt; 4ppan + adp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3974#ABBREVIATION:coaA#ECNUMBERS:2.7.1.33#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pantothenate kinase#ABBREVIATION:CoaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3974)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pnto_R_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4ppan_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PNTOt4" name="Pantothenate sodium symporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PNTOt4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: na1[e] + pnto-R[e] --&gt; na1[c] + pnto-R[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3258#ABBREVIATION:panF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:SSS, sodium/pantothenate symporter#ABBREVIATION:PanF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3258)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_na1_e" />
                    <speciesReference species="M_pnto_R_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_na1_c" />
                    <speciesReference species="M_pnto_R_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_POX" name="pyruvate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_POX</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.2.2.2</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : h2o + pyr + q8 --&gt; ac + co2 + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0871#ABBREVIATION:poxB#ECNUMBERS:1.2.2.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyruvate oxidase#ABBREVIATION:PoxB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0871)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPA" name="inorganic diphosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPA</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 3.6.1.1</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : h2o + ppi --&gt; h + (2) pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4226#ABBREVIATION:ppa#ECNUMBERS:3.6.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:inorganic pyrophosphatase#ABBREVIATION:Ppa#</html:p>
                    <html:p>GENE ASSOCIATION: (b4226)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPAKr" name="Propionate kinase">
                <notes>
                    <html:p>Abbreviation: R_PPAKr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.2.1</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : adp + ppap &lt;==&gt; atp + ppa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (R01353)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3115#ABBREVIATION:tdcD#ECNUMBERS:2.7.2.1,-!-,2.7.2.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:propionate kinase and acetate kinase II#ABBREVIATION:TdcD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3115)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_ppap_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ppa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPBNGS" name="porphobilinogen synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPBNGS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.24</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (2) 5aop --&gt; h + (2) h2o + ppbng</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0369#ABBREVIATION:hemB#ECNUMBERS:4.2.1.24#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Porphobilinogen synthase#ABBREVIATION:HemBec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0369)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5aop_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_ppbng_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPC" name="phosphoenolpyruvate carboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.31</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : co2 + h2o + pep --&gt; h + oaa + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3956#ABBREVIATION:ppc#ECNUMBERS:4.1.1.31#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoenolpyruvate carboxylase#ABBREVIATION:Ppc#</html:p>
                    <html:p>GENE ASSOCIATION: (b3956)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_oaa_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPCDC" name="phosphopantothenoylcysteine decarboxylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPCDC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.36</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4ppcys + h --&gt; co2 + pan4p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4ppcys_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_pan4p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPCK" name="phosphoenolpyruvate carboxykinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPCK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.49</html:p>
                    <html:p>SUBSYSTEM: Anaplerotic reactions</html:p>
                    <html:p>Equation: [c] : atp + oaa --&gt; adp + co2 + pep</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3403#ABBREVIATION:pck#ECNUMBERS:4.1.1.49#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoenolpyruvate carboxykinase#ABBREVIATION:Pck#</html:p>
                    <html:p>GENE ASSOCIATION: (b3403)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_pep_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPCSCT" name="Propanoyl-CoA: succinate CoA-transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPCSCT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : ppcoa + succ --&gt; ppa + succoa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2920#ABBREVIATION:ygfH#ECNUMBERS:2.8.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Propionyl-CoA: succinate CoA-transferase#ABBREVIATION:YgfH#</html:p>
                    <html:p>GENE ASSOCIATION: (b2920)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ppcoa_c" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppa_c" />
                    <speciesReference species="M_succoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPM" name="phosphopentomutase">
                <notes>
                    <html:p>Abbreviation: R_PPM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.7</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : r1p &lt;==&gt; r5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3380#ABBREVIATION:yhfW#</html:p>
                    <html:p>LOCUS:b4383#ABBREVIATION:deoB#ECNUMBERS:5.4.2.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphopentomutase#ABBREVIATION:DeoB#</html:p>
                    <html:p>NAME:putative phosphopentomutase#ABBREVIATION:YhfW#</html:p>
                    <html:p>GENE ASSOCIATION: (b4383) or (b3380)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_r1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPM2" name="phosphopentomutase 2 (deoxyribose)">
                <notes>
                    <html:p>Abbreviation: R_PPM2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.2.7</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : 2dr1p &lt;==&gt; 2dr5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv, JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4383#ABBREVIATION:deoB#ECNUMBERS:5.4.2.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphopentomutase#ABBREVIATION:DeoB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4383)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dr1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPNCL2" name="phosphopantothenate-cysteine ligase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPNCL2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.5</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4ppan + ctp + cys-L --&gt; 4ppcys + cmp + h + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4ppan_c" />
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_cys_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4ppcys_c" />
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPND" name="prephenate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPND</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.1.12</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : nad + pphn --&gt; 34hpp + co2 + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2600#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Chorismate mutase T#ABBREVIATION:TyrAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b2600)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_pphn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_34hpp_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPNDH" name="prephenate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPNDH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.51</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : h + pphn --&gt; co2 + h2o + phpyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2599#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Chorismate mutase P#ABBREVIATION:PheA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2599)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pphn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_phpyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPPGO" name="protoporphyrinogen oxidase (aerobic)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPPGO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.3.4</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (1.5) o2 + pppg9 --&gt; (3) h2o + ppp9</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>change name from PPPGO2 to PPPGO -tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3850#ABBREVIATION:hemG#ECNUMBERS:1.3.3.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:protoporphyrin oxidase#ABBREVIATION:HemG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3850)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_o2_c" stoichiometry="1.5" />
                    <speciesReference species="M_pppg9_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" stoichiometry="3" />
                    <speciesReference species="M_ppp9_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPPNDO" name="Phenylpropanoate Dioxygenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPPNDO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h + nadh + o2 + pppn --&gt; cechddd + nad</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR- see PMID 9603882</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2538#ABBREVIATION:hcaE#ECNUMBERS:1.14.1.-#</html:p>
                    <html:p>LOCUS:b2539#ABBREVIATION:hcaF#ECNUMBERS:1.14.1.-#</html:p>
                    <html:p>LOCUS:b2540#ABBREVIATION:hcaC#</html:p>
                    <html:p>LOCUS:b2542#ABBREVIATION:hcaD#ECNUMBERS:1.18.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-phenylpropionate dioxygenase#ABBREVIATION:HcaCDEF#</html:p>
                    <html:p>GENE ASSOCIATION: (b2542 and b2539 and b2538 and b2540)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_o2_c" />
                    <speciesReference species="M_pppn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cechddd_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPPNt2r" name="_3-phenylpropionate transport via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_PPPNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: h[e] + pppn[e] &lt;==&gt; h[c] + pppn[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2536#ABBREVIATION:hcaT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative 3-phenylpropionate transport, MFS#ABBREVIATION:HcaT#</html:p>
                    <html:p>GENE ASSOCIATION: (b2536)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_pppn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pppn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPS" name="phosphoenolpyruvate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.9.2</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : atp + h2o + pyr --&gt; amp + (2) h + pep + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP
Note: two protons generated</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1702#ABBREVIATION:pps#ECNUMBERS:2.7.9.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoenolpyruvate synthase#ABBREVIATION:Ppsa#</html:p>
                    <html:p>GENE ASSOCIATION: (b1702)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PPTGS" name="Peptidoglycan subunit synthesis" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PPTGS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : uaagmda --&gt; h + peptido_EC + udcpdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- the production of a subunit of peptidoglycan
tv- H pylori also uses the same form.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uaagmda_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_peptido_EC_c" />
                    <speciesReference species="M_udcpdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRAGSr" name="phosphoribosylglycinamide synthase">
                <notes>
                    <html:p>Abbreviation: R_PRAGSr</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 6.3.4.13</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + gly + pram &lt;==&gt; adp + gar + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of PRAGS
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4005#ABBREVIATION:purD#ECNUMBERS:6.3.4.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosylglycinamide synthetase#ABBREVIATION:PurDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4005)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gly_c" />
                    <speciesReference species="M_pram_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_gar_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRAIS" name="phosphoribosylaminoimidazole synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRAIS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.3.1</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + fpram --&gt; adp + air + (2) h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2499#ABBREVIATION:purM#ECNUMBERS:6.3.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosylaminoimidazole synthetase#ABBREVIATION:PurM#</html:p>
                    <html:p>GENE ASSOCIATION: (b2499)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_fpram_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_air_c" />
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRAIi" name="phosphoribosylanthranilate isomerase (irreversible)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRAIi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.24</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : pran --&gt; 2cpr5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added irreversible form of PRAI</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1262#ABBREVIATION:trpC#ECNUMBERS:5.3.1.24,-!-,4.1.1.48#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosyl anthranilate isomerase#ABBREVIATION:TrpCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1262)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pran_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2cpr5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRAMPC" name="phosphoribosyl-AMP cyclohydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRAMPC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.4.19</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + prbamp --&gt; prfp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2026#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI#</html:p>
                    <html:p>GENE ASSOCIATION: (b2026)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_prbamp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_prfp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRASCS" name="phosphoribosylaminoimidazolesuccinocarboxamide synthase">
                <notes>
                    <html:p>Abbreviation: R_PRASCS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.6</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : 5aizc + asp-L + atp &lt;==&gt; 25aics + adp + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2476#ABBREVIATION:purC#ECNUMBERS:6.3.2.6#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosyaminoimidazole-succinocarboxamide synthetase#ABBREVIATION:PurC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2476)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5aizc_c" />
                    <speciesReference species="M_asp_L_c" />
                    <speciesReference species="M_atp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_25aics_c" />
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRATPP" name="phosphoribosyl-ATP pyrophosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRATPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.31</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + prbatp --&gt; h + ppi + prbamp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2026#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI#</html:p>
                    <html:p>GENE ASSOCIATION: (b2026)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_prbatp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_prbamp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRFGS" name="phosphoribosylformylglycinamidine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRFGS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.5.3</html:p>
                    <html:p>SUBSYSTEM: Purine and Pyrimidine Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + fgam + gln-L + h2o --&gt; adp + fpram + glu-L + h + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2557#ABBREVIATION:purL#ECNUMBERS:6.3.5.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosylformylglycineamide synthetase#ABBREVIATION:PurL#</html:p>
                    <html:p>GENE ASSOCIATION: (b2557)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_fgam_c" />
                    <speciesReference species="M_gln_L_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fpram_c" />
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRMICIi" name="_1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (irreversible)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PRMICIi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.16</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : prfp --&gt; prlp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - added irreversible form of PRMICI</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2024#ABBREVIATION:hisA#ECNUMBERS:5.3.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoribosylformimino-5-amino-1-phosphoribosyl-4-imidazole carboxamide#ABBREVIATION:HisA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2024)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_prfp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_prlp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PROD2" name="Proline dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PROD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.5.99.8</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : fad + pro-L --&gt; 1pyr5c + fadh2 + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1014#ABBREVIATION:putA#ECNUMBERS:1.5.99.8,-!-,1.5.1.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Proline dehydrogenase and Pyrroline-5-carboxylate dehydrogenase#ABBREVIATION:PutAec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1014)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_pro_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_1pyr5c_c" />
                    <speciesReference species="M_fadh2_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PROabc" name="L-proline transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PROabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + pro-L[e] --&gt; adp[c] + h[c] + pi[c] + pro-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2677#ABBREVIATION:proV#</html:p>
                    <html:p>LOCUS:b2678#ABBREVIATION:proW#</html:p>
                    <html:p>LOCUS:b2679#ABBREVIATION:proX#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, glycine/betaine/proline (atp)#ABBREVIATION:ProVec#</html:p>
                    <html:p>NAME:ABC, glycine/betaine/proline (membrane)#ABBREVIATION:ProW#</html:p>
                    <html:p>NAME:ABC, glycine/betaine/proline (periplasm)#ABBREVIATION:ProX#</html:p>
                    <html:p>GENE ASSOCIATION: (b2679) and (b2677) and (b2678)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pro_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_pro_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PROt2r" name="L-proline reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_PROt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + pro-L[e] &lt;==&gt; h[c] + pro-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4111#ABBREVIATION:proP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, proline proton symport#ABBREVIATION:ProPec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4111)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_pro_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pro_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PROt4" name="Na+/Proline-L symporter" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PROt4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: na1[e] + pro-L[e] --&gt; na1[c] + pro-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1015#ABBREVIATION:putP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:SSS, proline sodium symport#ABBREVIATION:PutPec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1015)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_na1_e" />
                    <speciesReference species="M_pro_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_na1_c" />
                    <speciesReference species="M_pro_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PRPPS" name="phosphoribosylpyrophosphate synthetase">
                <notes>
                    <html:p>Abbreviation: R_PRPPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.6.1</html:p>
                    <html:p>SUBSYSTEM: Histidine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + r5p &lt;==&gt; amp + h + prpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1207#ABBREVIATION:prsA#ECNUMBERS:2.7.6.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphoribosylpyrophosphate synthetase#ABBREVIATION:PrsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1207)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_prpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PSCVT" name="_3-phosphoshikimate 1-carboxyvinyltransferase">
                <notes>
                    <html:p>Abbreviation: R_PSCVT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.19</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : pep + skm5p &lt;==&gt; 3psme + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0908#ABBREVIATION:aroA#ECNUMBERS:2.5.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_3-phosphoshikimate 1-carboxyvinyltransferase#ABBREVIATION:AroA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0908)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_skm5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3psme_c" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PSD_EC" name="Phosphatidylserine decarboxylase (Ecoli)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PSD_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.65</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : h + (0.02) ps_EC --&gt; co2 + (0.02) pe_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4160#ABBREVIATION:psd#ECNUMBERS:4.1.1.65#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphatidylserine decarboxylase#ABBREVIATION:Psd#</html:p>
                    <html:p>GENE ASSOCIATION: (b4160)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ps_EC_c" stoichiometry="0.02" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_pe_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PSERT" name="phosphoserine transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PSERT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.52</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : 3php + glu-L --&gt; akg + pser-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0907#ABBREVIATION:serC#ECNUMBERS:2.6.1.52#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0907)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3php_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_pser_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PSP_L" name="phosphoserine phosphatase (L-serine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PSP_L</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.3</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + pser-L --&gt; pi + ser-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4388#ABBREVIATION:serB#ECNUMBERS:3.1.3.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoserine phosphatase#ABBREVIATION:SerB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4388)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PSSA_EC" name="Phosphatidylserine syntase (Ecoli)">
                <notes>
                    <html:p>Abbreviation: R_PSSA_EC</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.8.8</html:p>
                    <html:p>SUBSYSTEM: Membrane Lipid Metabolism</html:p>
                    <html:p>Equation: [c] : (0.02) cdpdag_EC + ser-L &lt;==&gt; cmp + h + (0.02) ps_EC</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2585#ABBREVIATION:pssA#ECNUMBERS:2.7.8.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphatidylserine synthase#ABBREVIATION:PssA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2585)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.02" />
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cmp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ps_EC_c" stoichiometry="0.02" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTA2" name="Phosphate acetyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PTA2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : pi + ppcoa --&gt; coa + ppap</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR (R00921)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2297#ABBREVIATION:pta#ECNUMBERS:2.3.1.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphotransacetylase#ABBREVIATION:Pta#</html:p>
                    <html:p>GENE ASSOCIATION: (b2297)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppcoa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_ppap_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTAr" name="phosphotransacetylase">
                <notes>
                    <html:p>Abbreviation: R_PTAr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.8</html:p>
                    <html:p>SUBSYSTEM: Pyruvate Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + pi &lt;==&gt; actp + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of PTA reaction.  The reversible form already exists, but it is called PTA_do not use.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2297#ABBREVIATION:pta#ECNUMBERS:2.3.1.8#</html:p>
                    <html:p>LOCUS:b2458#ABBREVIATION:eutI#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphotransacetylase#ABBREVIATION:Pta#</html:p>
                    <html:p>NAME:putative phosphate acetyltransferase#ABBREVIATION:EutD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2297) or (b2458)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_actp_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTPATi" name="pantetheine-phosphate adenylyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PTPATi</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + h + pan4p --&gt; dpcoa + ppi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- irreversible form of PTPAT</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3634#ABBREVIATION:coaD#ECNUMBERS:2.7.7.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:phosphopantetheine adenyltransferase#ABBREVIATION:CoaD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3634)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pan4p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dpcoa_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTRCORNt7" name="putrescine/ornithine antiporter">
                <notes>
                    <html:p>Abbreviation: R_PTRCORNt7</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: orn[c] + ptrc[e] &lt;==&gt; orn[e] + ptrc[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>AR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0692#ABBREVIATION:potE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, putrescine/ornithine antiporter#ABBREVIATION:PotEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0692)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_orn_c" />
                    <speciesReference species="M_ptrc_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_orn_e" />
                    <speciesReference species="M_ptrc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTRCTA" name="Putrescine Transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PTRCTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.29</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : akg + ptrc --&gt; 4abutn + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR-</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_ptrc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4abutn_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTRCabc" name="putrescine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PTRCabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + ptrc[e] --&gt; adp[c] + h[c] + pi[c] + ptrc[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0854#ABBREVIATION:potF#</html:p>
                    <html:p>LOCUS:b0855#ABBREVIATION:potG#</html:p>
                    <html:p>LOCUS:b0856#ABBREVIATION:potH#</html:p>
                    <html:p>LOCUS:b0857#ABBREVIATION:potI#</html:p>
                    <html:p>LOCUS:b1123#ABBREVIATION:potD#</html:p>
                    <html:p>LOCUS:b1124#ABBREVIATION:potC#</html:p>
                    <html:p>LOCUS:b1125#ABBREVIATION:potB#</html:p>
                    <html:p>LOCUS:b1126#ABBREVIATION:potA#</html:p>
                    <html:p>LOCUS:b1440#ABBREVIATION:ydcS#</html:p>
                    <html:p>LOCUS:b1441#ABBREVIATION:ydcT#</html:p>
                    <html:p>LOCUS:b1442#ABBREVIATION:ydcU#</html:p>
                    <html:p>LOCUS:b1443#ABBREVIATION:ydcV#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(atp)#ABBREVIATION:PotA#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(membrane)#ABBREVIATION:PotB#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(membrane)#ABBREVIATION:PotC#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(periplasm)#ABBREVIATION:PotDec#</html:p>
                    <html:p>NAME:ABC, putrescine(periplasm)#ABBREVIATION:PotF#</html:p>
                    <html:p>NAME:ABC, putrescine(atp)#ABBREVIATION:PotG#</html:p>
                    <html:p>NAME:ABC, putrescine(membrane)#ABBREVIATION:PotH#</html:p>
                    <html:p>NAME:ABC, putrescine(membrane)#ABBREVIATION:PotI#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (atp_bind)#ABBREVIATION:YdcT#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (membrane)#ABBREVIATION:YdcU#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (membrane)#ABBREVIATION:YdcV#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (atp_bind)#ABBREVIATION:YdcS#</html:p>
                    <html:p>GENE ASSOCIATION: (b0855) and (b0857) and (b0854) and (b0856) or (b1443) and (b1442) and (b1440) and (b1441) or (b1123) and (b1125) and (b1124) and (b1126)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ptrc_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ptrc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PTRCt2r" name="putrescine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_PTRCt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ptrc[e] &lt;==&gt; h[c] + ptrc[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0692#ABBREVIATION:potE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:APC, putrescine/ornithine antiporter#ABBREVIATION:PotEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0692)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ptrc_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ptrc_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP1" name="purine-nucleoside phosphorylase (Adenosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : adn + pi &lt;==&gt; ade + r1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ade_c" />
                    <speciesReference species="M_r1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP2" name="purine-nucleoside phosphorylase (Deoxyadenosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dad-2 + pi &lt;==&gt; 2dr1p + ade</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dad_2_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr1p_c" />
                    <speciesReference species="M_ade_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP3" name="purine-nucleoside phosphorylase (Guanosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gsn + pi &lt;==&gt; gua + r1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gsn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gua_c" />
                    <speciesReference species="M_r1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP4" name="purine-nucleoside phosphorylase (Deoxyguanosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dgsn + pi &lt;==&gt; 2dr1p + gua</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dgsn_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr1p_c" />
                    <speciesReference species="M_gua_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP5" name="purine-nucleoside phosphorylase (Inosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP5</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ins + pi &lt;==&gt; hxan + r1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ins_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_hxan_c" />
                    <speciesReference species="M_r1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP6" name="purine-nucleoside phosphorylase (Deoxyinosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP6</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : din + pi &lt;==&gt; 2dr1p + hxan</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_din_c" />
                    <speciesReference species="M_pi_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr1p_c" />
                    <speciesReference species="M_hxan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PUNP7" name="purine-nucleoside phosphorylase (Xanthosine)">
                <notes>
                    <html:p>Abbreviation: R_PUNP7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : pi + xtsn &lt;==&gt; r1p + xan</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferasextsn	</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2407#ABBREVIATION:xapA#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>LOCUS:b4384#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD#</html:p>
                    <html:p>NAME:Xanthosine phosphorylase#ABBREVIATION:XapA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2407) or (b4384)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_xtsn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_r1p_c" />
                    <speciesReference species="M_xan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYAM5PO" name="pyridoxamine 5'-phosphate oxidase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYAM5PO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.4.3.5</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + o2 + pyam5p --&gt; h2o2 + nh4 + pydx5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1638#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1638)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_o2_c" />
                    <speciesReference species="M_pyam5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o2_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYDAMK" name="pyridoxamine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYDAMK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.35</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + pydam --&gt; adp + h + pyam5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2418#ABBREVIATION:pdxK#ECNUMBERS:2.7.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyridoxal-pyridoxamine kinase and hydroxymethylpyrimidine kinase#ABBREVIATION:PdxK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2418)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pydam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyam5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYDXK" name="pyridoxal kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYDXK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.35</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + pydx --&gt; adp + h + pydx5p</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1636#ABBREVIATION:pdxY#ECNUMBERS:2.7.1.35#</html:p>
                    <html:p>LOCUS:b2418#ABBREVIATION:pdxK#ECNUMBERS:2.7.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyridoxal-pyridoxamine kinase and hydroxymethylpyrimidine kinase#ABBREVIATION:PdxK#</html:p>
                    <html:p>NAME:Pyridoxal kinase#ABBREVIATION:PdxYec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1636) or (b2418)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pydx_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYDXNK" name="pyridoxine kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYDXNK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.35</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + pydxn --&gt; adp + h + pdx5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD
JLR-Pyridoxine, pyridoxamine and various derivatives can also act as acceptors</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2418#ABBREVIATION:pdxK#ECNUMBERS:2.7.1.35#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyridoxal-pyridoxamine kinase and hydroxymethylpyrimidine kinase#ABBREVIATION:PdxK#</html:p>
                    <html:p>GENE ASSOCIATION: (b2418)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pydxn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pdx5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYDXPP" name="Pyridoxal 5-phosphate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYDXPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + pydx5p --&gt; pi + pydx</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_pydx5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_pydx_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYK" name="pyruvate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_PYK</html:p>
                    <html:p>Synonyms: _7</html:p>
                    <html:p>EC Number: 2.7.1.40</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : adp + h + pep --&gt; atp + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1854#ABBREVIATION:pykA#ECNUMBERS:2.7.1.40#</html:p>
                    <html:p>LOCUS:b1676#ABBREVIATION:pykF#ECNUMBERS:2.7.1.40#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyruvate kinase  II#ABBREVIATION:Pyka#</html:p>
                    <html:p>NAME:pyruvate kinase I#ABBREVIATION:Pykf#</html:p>
                    <html:p>GENE ASSOCIATION: (b1854) or (b1676)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pep_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYNP2r" name="pyrimidine-nucleoside phosphorylase (uracil)">
                <notes>
                    <html:p>Abbreviation: R_PYNP2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : pi + uri &lt;==&gt; r1p + ura</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of PYNP2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3831#ABBREVIATION:udp#ECNUMBERS:2.4.2.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uridine phosphorylase#ABBREVIATION:Udp#</html:p>
                    <html:p>GENE ASSOCIATION: (b3831)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_uri_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_r1p_c" />
                    <speciesReference species="M_ura_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_PYRt2r" name="pyruvate reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_PYRt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + pyr[e] &lt;==&gt; h[c] + pyr[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_pyr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_QULNS" name="quinolinate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_QULNS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dhap + iasp --&gt; h + (2) h2o + pi + quln</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0750#ABBREVIATION:nadA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Quinolinate synthetase A#ABBREVIATION:NadA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0750)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_iasp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_quln_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBFK" name="riboflavin kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RBFK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.26</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + ribflv --&gt; adp + fmn + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0025#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibFec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0025)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ribflv_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_fmn_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBFSa" name="riboflavin synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RBFSa</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.9</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 4r5au + db4p --&gt; dmlz + (2) h2o + pi</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1662#ABBREVIATION:ribC#ECNUMBERS:2.5.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_6,7-dimethyl-8-ribityllumazine synthase#ABBREVIATION:RibCec#</html:p>
                    <html:p>GENE ASSOCIATION: (b1662)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_4r5au_c" />
                    <speciesReference species="M_db4p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dmlz_c" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_pi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBFSb" name="riboflavin synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RBFSb</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.9</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (2) dmlz --&gt; 4r5au + ribflv</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0415#ABBREVIATION:ribE#ECNUMBERS:2.5.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:riboflavin synthase#ABBREVIATION:RibH#</html:p>
                    <html:p>GENE ASSOCIATION: (b0415)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dmlz_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4r5au_c" />
                    <speciesReference species="M_ribflv_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBK" name="ribokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RBK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.15</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + rib-D --&gt; adp + h + r5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3752#ABBREVIATION:rbsK#ECNUMBERS:2.7.1.15#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ribokinase#ABBREVIATION:RbsK#</html:p>
                    <html:p>GENE ASSOCIATION: (b3752)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_rib_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_r5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBK_L1" name="L-ribulokinase (L-ribulose)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RBK_L1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.16</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + rbl-L --&gt; adp + h + ru5p-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Ribitol and L-arabinitol can also act as acceptors. </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0063#ABBREVIATION:araB#ECNUMBERS:2.7.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-ribulokinase#ABBREVIATION:AraB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0063)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_rbl_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ru5p_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RBP4E" name="L-ribulose-phosphate 4-epimerase">
                <notes>
                    <html:p>Abbreviation: R_RBP4E</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.3.4</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : ru5p-L &lt;==&gt; xu5p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0061#ABBREVIATION:araD#ECNUMBERS:5.1.3.4#</html:p>
                    <html:p>LOCUS:b3583#ABBREVIATION:sgbE#ECNUMBERS:5.1.3.4#</html:p>
                    <html:p>LOCUS:b4198#ABBREVIATION:ulaF#ECNUMBERS:5.1.3.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-ribulose-5-phosphate 4-epimerase#ABBREVIATION:AraD#</html:p>
                    <html:p>NAME:L-ribulose-5-phosphate 4-epimerase#ABBREVIATION:SgbE#</html:p>
                    <html:p>NAME:L-ribulose-5-phosphate 4-epimerase#ABBREVIATION:SgaE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0061) or (b3583) or (b4198)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ru5p_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xu5p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RHCCE" name="S-ribosylhomocysteine cleavage enzyme" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RHCCE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : rhcys --&gt; dhptd + hcys-L</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2687#ABBREVIATION:luxS#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:S-ribosylhomocysteine cleavage enzyme#ABBREVIATION:LuxS#</html:p>
                    <html:p>GENE ASSOCIATION: (b2687)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_rhcys_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhptd_c" />
                    <speciesReference species="M_hcys_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RIBabc" name="D-ribose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RIBabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + rib-D[e] --&gt; adp[c] + h[c] + pi[c] + rib-D[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3748#ABBREVIATION:rbsD#</html:p>
                    <html:p>LOCUS:b3749#ABBREVIATION:rbsA#</html:p>
                    <html:p>LOCUS:b3750#ABBREVIATION:rbsC#</html:p>
                    <html:p>LOCUS:b3751#ABBREVIATION:rbsB#</html:p>
                    <html:p>LOCUS:b4227#ABBREVIATION:ytfQ#</html:p>
                    <html:p>LOCUS:b4228#ABBREVIATION:OBSOLETE (ytfR)#</html:p>
                    <html:p>LOCUS:b4229#ABBREVIATION:OBSOLETE (ytfS)#</html:p>
                    <html:p>LOCUS:b4230#ABBREVIATION:ytfT#</html:p>
                    <html:p>LOCUS:b4231#ABBREVIATION:yjfF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, D-ribose (atp)#ABBREVIATION:RbsA#</html:p>
                    <html:p>NAME:ABC, D-ribose (periplasm)#ABBREVIATION:RbsB#</html:p>
                    <html:p>NAME:ABC, D-ribose (membrane)#ABBREVIATION:RbsC#</html:p>
                    <html:p>NAME:putative ABC, D-ribose transporter (peri_bind)#ABBREVIATION:YtfQ#</html:p>
                    <html:p>NAME:putative ABC, D-ribose transporter (atp_bind)#ABBREVIATION:YtfR#</html:p>
                    <html:p>NAME:putative ABC, D-ribose transporter (atp_bind)#ABBREVIATION:YtfS#</html:p>
                    <html:p>NAME:putative ABC, D-ribose transporter (membrane)#ABBREVIATION:YtfT#</html:p>
                    <html:p>NAME:putative ABC, D-ribose transporter (membrane)#ABBREVIATION:YjfF#</html:p>
                    <html:p>NAME:D-ribose transport, membrane associated protein#ABBREVIATION:RbsDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b4229) and (b4231) and (b4230) and (b4227) and (b4228) or (b3750) and (b3749) and (b3751) and (b3748)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_rib_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_rib_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RMI" name="L-rhamnose isomerase">
                <notes>
                    <html:p>Abbreviation: R_RMI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.14</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : rmn &lt;==&gt; rml</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3903#ABBREVIATION:rhaA#ECNUMBERS:5.3.1.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-rhamnose isomerase#ABBREVIATION:RhaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3903)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_rmn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_rml_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RMK" name="rhamnulokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RMK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.5</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + rml --&gt; adp + h + rml1p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3904#ABBREVIATION:rhaB#ECNUMBERS:2.7.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:rhamnulokinase#ABBREVIATION:RhaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3904)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_rml_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_rml1p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RMNt" name="L-rhamnose transport via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RMNt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + rmn[e] --&gt; h[c] + rmn[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3907#ABBREVIATION:rhaT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DMT, L-rhamnose H: symporter#ABBREVIATION:RhaT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3907)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_rmn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_rmn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RMPA" name="Rhamnulose-1-phosphate aldolase">
                <notes>
                    <html:p>Abbreviation: R_RMPA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.19</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : rml1p &lt;==&gt; dhap + lald-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3902#ABBREVIATION:rhaD#ECNUMBERS:4.1.2.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:rhamnulose-1-phosphate aldolase#ABBREVIATION:RhaD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3902)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_rml1p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_lald_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNDR1" name="ribonucleoside-diphosphate reductase (ADP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNDR1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : adp + trdrd --&gt; dadp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2234#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2235#ABBREVIATION:nrdB#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ribonucleoside diphosphate reductase#ABBREVIATION:NrdA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2234 and b2235)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dadp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNDR2" name="ribonucleoside-diphosphate reductase (GDP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNDR2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gdp + trdrd --&gt; dgdp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2234#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2235#ABBREVIATION:nrdB#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ribonucleoside diphosphate reductase#ABBREVIATION:NrdA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2234 and b2235)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgdp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNDR3" name="ribonucleoside-diphosphate reductase (CDP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNDR3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : cdp + trdrd --&gt; dcdp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2234#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2235#ABBREVIATION:nrdB#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2675#ABBREVIATION:nrdE#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2676#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ribonucleoside diphosphate reductase#ABBREVIATION:NrdA#</html:p>
                    <html:p>NAME:ribonucleoside-diphosphate reductase II#ABBREVIATION:NrdE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2234 and b2235) or (b2675 and b2676)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cdp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dcdp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNDR4" name="ribonucleoside-diphosphate reductase (UDP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNDR4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.1</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : trdrd + udp --&gt; dudp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2234#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>LOCUS:b2235#ABBREVIATION:nrdB#ECNUMBERS:1.17.4.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ribonucleoside diphosphate reductase#ABBREVIATION:NrdA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2234 and b2235)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_trdrd_c" />
                    <speciesReference species="M_udp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dudp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNTR1" name="ribonucleoside-triphosphate reductase (ATP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNTR1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + trdrd --&gt; datp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4238#ABBREVIATION:nrdD#ECNUMBERS:1.17.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ribonucleoside-triphosphate reductase#ABBREVIATION:NrdD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_datp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNTR2" name="ribonucleoside-triphosphate reductase (GTP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNTR2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gtp + trdrd --&gt; dgtp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4238#ABBREVIATION:nrdD#ECNUMBERS:1.17.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ribonucleoside-triphosphate reductase#ABBREVIATION:NrdD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dgtp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNTR3" name="ribonucleoside-triphosphate reductase (CTP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNTR3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : ctp + trdrd --&gt; dctp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4238#ABBREVIATION:nrdD#ECNUMBERS:1.17.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ribonucleoside-triphosphate reductase#ABBREVIATION:NrdD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ctp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dctp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RNTR4" name="ribonucleoside-triphosphate reductase (UTP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RNTR4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.17.4.2</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : trdrd + utp --&gt; dutp + h2o + trdox</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4238#ABBREVIATION:nrdD#ECNUMBERS:1.17.4.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ribonucleoside-triphosphate reductase#ABBREVIATION:NrdD#</html:p>
                    <html:p>GENE ASSOCIATION: (b4238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_trdrd_c" />
                    <speciesReference species="M_utp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dutp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RPE" name="ribulose 5-phosphate 3-epimerase">
                <notes>
                    <html:p>Abbreviation: R_RPE</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.3.1</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : ru5p-D &lt;==&gt; xu5p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3386#ABBREVIATION:rpe#ECNUMBERS:5.1.3.1#</html:p>
                    <html:p>LOCUS:b4301#ABBREVIATION:sgcE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-ribulose-5-phosphate 3-epimerase#ABBREVIATION:Rpeec#</html:p>
                    <html:p>NAME:putative ribulose-phosphate 3-epimerase#ABBREVIATION:SgcE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3386) or (b4301)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ru5p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xu5p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RPI" name="ribose-5-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_RPI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.6</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : r5p &lt;==&gt; ru5p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2914#ABBREVIATION:rpiA#ECNUMBERS:5.3.1.6#</html:p>
                    <html:p>LOCUS:b4090#ABBREVIATION:rpiB#ECNUMBERS:5.3.1.6,-!-,5.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Ribose-5-phosphate isomerase A#ABBREVIATION:RpiA#</html:p>
                    <html:p>NAME:ribose-5-phosphate isomerase B#ABBREVIATION:RpiB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2914) or (b4090)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_r5p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ru5p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_RZ5PP" name="alpha-ribazole 5-phosphate phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_RZ5PP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 5prdmbz + h2o --&gt; pi + rdmbzi</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR (Kegg Rxn R04594)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0638#ABBREVIATION:cobC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:alpha-ribazole-5'-phosphatase#ABBREVIATION:PhpB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0638)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_5prdmbz_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_rdmbzi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_S7PI" name="sedoheptulose 7-phosphate isomerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_S7PI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : s7p --&gt; gmhep7p</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR Kegg RXN R05645</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0222#ABBREVIATION:lpcA#ECNUMBERS:5.-.-.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Phosphoheptose isomerase#ABBREVIATION:GmhA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0222)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_s7p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gmhep7p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SADH" name="Succinylarginine dihydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SADH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.69</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : (2) h + (2) h2o + sucarg --&gt; co2 + (2) nh4 + sucorn</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- had to add h2o to balance (R04189)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1748#ABBREVIATION:astC#ECNUMBERS:2.6.1.17,-!-,2.6.1.11#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Succinylornithine transaminase#ABBREVIATION:AstC#</html:p>
                    <html:p>GENE ASSOCIATION: (b1748)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" stoichiometry="2" />
                    <speciesReference species="M_sucarg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_nh4_c" stoichiometry="2" />
                    <speciesReference species="M_sucorn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SADT2" name="Sulfate adenyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SADT2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + gtp + h2o + so4 --&gt; aps + gdp + pi + ppi</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2751#ABBREVIATION:cysN#ECNUMBERS:2.7.7.4#</html:p>
                    <html:p>LOCUS:b2752#ABBREVIATION:cysD#ECNUMBERS:2.7.7.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ATP-sulfurylase#ABBREVIATION:CysD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2751 and b2752)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_so4_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aps_c" />
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SBTPD" name="sorbitol-6-phosphate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_SBTPD</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.1.1.140</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : nad + sbt6p &lt;==&gt; f6p + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2705#ABBREVIATION:srlD#ECNUMBERS:1.1.1.140#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:glucitol-6-phosphate dehydrogenase#ABBREVIATION:SrlD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2705)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_sbt6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SBTpts" name="D-sorbitol transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SBTpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: pep[c] + sbt-D[e] --&gt; pyr[c] + sbt6p[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2702#ABBREVIATION:srlA#</html:p>
                    <html:p>LOCUS:b2703#ABBREVIATION:srlE#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2704#ABBREVIATION:srlB#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, glucitol/sorbitol IIC#ABBREVIATION:SrlA#</html:p>
                    <html:p>NAME:PTS, glucitol/sorbitol IIA#ABBREVIATION:SrlB#</html:p>
                    <html:p>NAME:PTS, glucitol/sorbitol IIB#ABBREVIATION:SrlE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2703) and (b2415) and (b2702) and (b2416) and (b2704)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_sbt_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_sbt6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SDPDS" name="succinyl-diaminopimelate desuccinylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SDPDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.1.18</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + sl26da --&gt; 26dap-LL + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2472#ABBREVIATION:dapE#ECNUMBERS:3.5.1.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Succinyl-diaminopimelate desuccinylase#ABBREVIATION:DapE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2472)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_sl26da_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_26dap_LL_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SDPTA" name="succinyldiaminopimelate transaminase">
                <notes>
                    <html:p>Abbreviation: R_SDPTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.17</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : akg + sl26da &lt;==&gt; glu-L + sl2a6o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_sl26da_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_sl2a6o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SELNPS" name="Selenophosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SELNPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.9.3</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : atp + h2o + seln --&gt; amp + pi + selnp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1764#ABBREVIATION:selD#ECNUMBERS:2.7.9.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Selenophosphate synthetase#ABBREVIATION:SelD#</html:p>
                    <html:p>GENE ASSOCIATION: (b1764)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_seln_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_selnp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERASr" name="(L-seryl)adenylate synthase">
                <notes>
                    <html:p>Abbreviation: R_SERASr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + h + ser-L &lt;==&gt; ppi + seramp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0586#ABBREVIATION:entF#ECNUMBERS:2.7.7.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:adenosinylation of serine#ABBREVIATION:EntF#</html:p>
                    <html:p>GENE ASSOCIATION: (b0586)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_seramp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERAT" name="serine O-acetyltransferase">
                <notes>
                    <html:p>Abbreviation: R_SERAT</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 2.3.1.30</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + ser-L &lt;==&gt; acser + coa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3607#ABBREVIATION:cysE#ECNUMBERS:2.3.1.30#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine acetyltransferase#ABBREVIATION:CysE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3607)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acser_c" />
                    <speciesReference species="M_coa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERD_D" name="D-serine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SERD_D</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : ser-D --&gt; nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previous EC 4.2.1.14. Now EC 4.3.1.18</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2366#ABBREVIATION:dsdA#ECNUMBERS:4.3.1.18#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-serine deaminase#ABBREVIATION:DsdA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2366)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ser_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERD_L" name="L-serine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SERD_L</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.3.1.17</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : ser-L --&gt; nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previous EC 4.2.1.13. Now EC 4.3.1.17</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1814#ABBREVIATION:sdaA#ECNUMBERS:4.3.1.17#</html:p>
                    <html:p>LOCUS:b2797#ABBREVIATION:sdaB#ECNUMBERS:4.3.1.17#</html:p>
                    <html:p>LOCUS:b3111#ABBREVIATION:OBSOLETE (tdcGa)#</html:p>
                    <html:p>LOCUS:b3112#ABBREVIATION:OBSOLETE (tdcGb)#</html:p>
                    <html:p>LOCUS:b3708#ABBREVIATION:tnaA#ECNUMBERS:4.1.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tryptophan deaminase#ABBREVIATION:TnaA#</html:p>
                    <html:p>NAME:Serine deaminase I#ABBREVIATION:SdaAec#</html:p>
                    <html:p>NAME:Serine deaminase II#ABBREVIATION:SdaB#</html:p>
                    <html:p>NAME:L-serine dehydratase#ABBREVIATION:TdcG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3708) or (b1814) or (b3112 and b3111) or (b2797)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERt2r" name="L-serine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_SERt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ser-L[e] &lt;==&gt; h[c] + ser-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2796#ABBREVIATION:sdaC#</html:p>
                    <html:p>LOCUS:b3116#ABBREVIATION:tdcC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine transporter#ABBREVIATION:SdaC#</html:p>
                    <html:p>NAME:L-threonine/L-serine proton symport#ABBREVIATION:TdcC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3116) or (b2796)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ser_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SERt4" name="L-serine via sodium symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SERt4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: na1[e] + ser-L[e] --&gt; na1[c] + ser-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3089#ABBREVIATION:sstT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DAACS Na:serine/threonine symporter#ABBREVIATION:SstT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3089)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_na1_e" />
                    <speciesReference species="M_ser_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_na1_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SGDS" name="Succinylglutamate desuccinylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SGDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + sucglu --&gt; glu-L + succ</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- (R00411)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1744#ABBREVIATION:astE#ECNUMBERS:3.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Succinylglutamate desuccinylase#ABBREVIATION:AstE#</html:p>
                    <html:p>GENE ASSOCIATION: (b1744)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_sucglu_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SGSAD" name="Succinylglutamic semialdehyde dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SGSAD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + nad + sucgsa --&gt; (2) h + nadh + sucglu</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- had to add h2o to balance (R05049)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1746#ABBREVIATION:astD#ECNUMBERS:1.2.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Succinylglutamic semialdehyde dehydrogenase#ABBREVIATION:AstD#</html:p>
                    <html:p>GENE ASSOCIATION: (b1746)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_sucgsa_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_sucglu_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHCHCS2" name="_2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SHCHCS2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : ichor + ssaltpp --&gt; 2shchc + pyr + thmpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2264#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.5.1.64#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:a-ketoglutarate decarboxylase and SHCHC cynthase#ABBREVIATION:MenD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2264)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ichor_c" />
                    <speciesReference species="M_ssaltpp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2shchc_c" />
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_thmpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHCHD2" name="sirohydrochlorin dehydrogenase (NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SHCHD2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : dscl + nad --&gt; h + nadh + scl</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- uses nad rather than nadp (SHCHD)
EC 1.3.1.76</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3368#ABBREVIATION:cysG#ECNUMBERS:2.1.1.107,-!-,4.99.1.-,-!-,1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:siroheme synthase#ABBREVIATION:CysG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3368)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dscl_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_scl_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHCHF" name="sirohydrochlorin ferrochetalase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SHCHF</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : fe2 + scl --&gt; (3) h + sheme</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>EC  4.99.1.4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3368#ABBREVIATION:cysG#ECNUMBERS:2.1.1.107,-!-,4.99.1.-,-!-,1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:siroheme synthase#ABBREVIATION:CysG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3368)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fe2_c" />
                    <speciesReference species="M_scl_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_sheme_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHK3Dr" name="shikimate dehydrogenase">
                <notes>
                    <html:p>Abbreviation: R_SHK3Dr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.25</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 3dhsk + h + nadph &lt;==&gt; nadp + skm</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- added reversible form of SHK3D
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1692#ABBREVIATION:ydiB#ECNUMBERS:1.1.1.25#</html:p>
                    <html:p>LOCUS:b3281#ABBREVIATION:aroE#ECNUMBERS:1.1.1.25#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Shikimate dehydrogenase#ABBREVIATION:AroEec#</html:p>
                    <html:p>NAME:putative shikimate 5-dehydrogenase#ABBREVIATION:YdiB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3281) or (b1692)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3dhsk_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_skm_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHKK" name="shikimate kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SHKK</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.71</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : atp + skm --&gt; adp + h + skm5p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0388#ABBREVIATION:aroL#ECNUMBERS:2.7.1.71#</html:p>
                    <html:p>LOCUS:b3390#ABBREVIATION:aroK#ECNUMBERS:2.7.1.71#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Skikimic acid kinase I#ABBREVIATION:AroK#</html:p>
                    <html:p>NAME:shikimate kinase II#ABBREVIATION:AroL#</html:p>
                    <html:p>GENE ASSOCIATION: (b3390) or (b0388)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_skm_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_skm5p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SHSL1" name="O-succinylhomoserine lyase (L-cysteine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SHSL1</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.2.99.9</html:p>
                    <html:p>SUBSYSTEM: Methionine Metabolism</html:p>
                    <html:p>Equation: [c] : cys-L + suchms --&gt; cyst-L + h + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>new EC - EC 2.5.1.48
NJ</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3939#ABBREVIATION:metB#ECNUMBERS:2.5.1.48#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Cystathionine gamma-synthase#ABBREVIATION:MetB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3939)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_suchms_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_cyst_L_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SOTA" name="Succinylornithine transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SOTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : akg + sucorn --&gt; glu-L + sucgsa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR (R04217)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1745#ABBREVIATION:astB#ECNUMBERS:3.5.3.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:succinylarginine dihydrolase#ABBREVIATION:AstB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1745)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_sucorn_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glu_L_c" />
                    <speciesReference species="M_sucgsa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SPMDAT1" name="Spermidine acetyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SPMDAT1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.57</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + spmd --&gt; N1aspmd + coa + h</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR
rxn DIAMT was redundant and has been deleted - NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1584#ABBREVIATION:speG#ECNUMBERS:2.3.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:spermidine N1-acetyltransferase#ABBREVIATION:SpeG#</html:p>
                    <html:p>GENE ASSOCIATION: (b1584)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_N1aspmd_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SPMDAT2" name="Spermidine acetyltransferase (N8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SPMDAT2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.57</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : accoa + spmd --&gt; coa + h + n8aspmd</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1584#ABBREVIATION:speG#ECNUMBERS:2.3.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:spermidine N1-acetyltransferase#ABBREVIATION:SpeG#</html:p>
                    <html:p>GENE ASSOCIATION: (b1584)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_n8aspmd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SPMDabc" name="spermidine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SPMDabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + spmd[e] --&gt; adp[c] + h[c] + pi[c] + spmd[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1123#ABBREVIATION:potD#</html:p>
                    <html:p>LOCUS:b1124#ABBREVIATION:potC#</html:p>
                    <html:p>LOCUS:b1125#ABBREVIATION:potB#</html:p>
                    <html:p>LOCUS:b1126#ABBREVIATION:potA#</html:p>
                    <html:p>LOCUS:b1440#ABBREVIATION:ydcS#</html:p>
                    <html:p>LOCUS:b1441#ABBREVIATION:ydcT#</html:p>
                    <html:p>LOCUS:b1442#ABBREVIATION:ydcU#</html:p>
                    <html:p>LOCUS:b1443#ABBREVIATION:ydcV#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(atp)#ABBREVIATION:PotA#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(membrane)#ABBREVIATION:PotB#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(membrane)#ABBREVIATION:PotC#</html:p>
                    <html:p>NAME:ABC, spermidine/putrescine(periplasm)#ABBREVIATION:PotDec#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (atp_bind)#ABBREVIATION:YdcT#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (membrane)#ABBREVIATION:YdcU#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (membrane)#ABBREVIATION:YdcV#</html:p>
                    <html:p>NAME:putative ABC spermidine/putrescine transporter (atp_bind)#ABBREVIATION:YdcS#</html:p>
                    <html:p>GENE ASSOCIATION: (b1443) and (b1442) and (b1440) and (b1441) or (b1123) and (b1124) and (b1125) and (b1126)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_spmd_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SPMS" name="spermidine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SPMS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.16</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : ametam + ptrc --&gt; 5mta + h + spmd</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0121#ABBREVIATION:speE#ECNUMBERS:2.5.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Spermidine synthase#ABBREVIATION:SpeE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0121)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ametam_c" />
                    <speciesReference species="M_ptrc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_5mta_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_spmd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SPODM" name="superoxide dismutase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SPODM</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.15.1.1</html:p>
                    <html:p>SUBSYSTEM: Unassigned</html:p>
                    <html:p>Equation: [c] : (2) h + (2) o2s --&gt; h2o2 + o2</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1646#ABBREVIATION:sodC#ECNUMBERS:1.15.1.1#</html:p>
                    <html:p>LOCUS:b1656#ABBREVIATION:sodB#ECNUMBERS:1.15.1.1#</html:p>
                    <html:p>LOCUS:b3908#ABBREVIATION:sodA#ECNUMBERS:1.15.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:superoxide dismutase, Mn#ABBREVIATION:SodA#</html:p>
                    <html:p>NAME:superoxide dismutase, Fe#ABBREVIATION:SodB#</html:p>
                    <html:p>NAME:superoxide dismutase, Cu-Zn#ABBREVIATION:SodC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3908) or (b1646) or (b1656)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_o2s_c" stoichiometry="2" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o2_c" />
                    <speciesReference species="M_o2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SSALx" name="succinate-semialdehyde dehydrogenase (NAD)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SSALx</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.24</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + nad + sucsal --&gt; (2) h + nadh + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_sucsal_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SSALy" name="succinate-semialdehyde dehydrogenase (NADP)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SSALy</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.2.1.16</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + nadp + sucsal --&gt; (2) h + nadph + succ</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2661#ABBREVIATION:gabD#ECNUMBERS:1.2.1.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:succinate-semialdehyde dehydrogenase#ABBREVIATION:GabD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2661)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_sucsal_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCBZL" name="o-succinylbenzoate-CoA ligase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCBZL</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.2.1.26</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + coa + sucbz --&gt; amp + ppi + sbzcoa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2260#ABBREVIATION:menE#ECNUMBERS:6.2.1.26#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:O-succinylbenzoate-CoA ligase#ABBREVIATION:MenE#</html:p>
                    <html:p>GENE ASSOCIATION: (b2260)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_sucbz_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_sbzcoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCBZS" name="O-succinylbenzoate-CoA synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCBZS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2shchc --&gt; h2o + sucbz</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2261#ABBREVIATION:menC#ECNUMBERS:4.2.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:O-succinylbenzoate-CoA synthase#ABBREVIATION:MenC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2261)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2shchc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_sucbz_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCCabc" name="Succinate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCCabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + succ[e] --&gt; adp[c] + h[c] + pi[c] + succ[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3579#ABBREVIATION:yiaO#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-xylulose transport periplasmic binding protein (TRAP)#ABBREVIATION:YiaO#</html:p>
                    <html:p>GENE ASSOCIATION: (b3579)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_succ_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCCt2_2" name="succinate transport via proton symport (2 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCCt2_2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (2) h[e] + succ[e] --&gt; (2) h[c] + succ[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3528#ABBREVIATION:dctA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3528)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_succ_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCCt2_3" name="Succintate transport via proton symport (3 H)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCCt2_3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: (3) h[e] + succ[e] --&gt; (3) h[c] + succ[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4123#ABBREVIATION:dcuB#</html:p>
                    <html:p>LOCUS:b4138#ABBREVIATION:dcuA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Anaerobic C4-dicarboxylate transporter protein#ABBREVIATION:DcuA#</html:p>
                    <html:p>NAME:anaerobic C4-dicarboxylate transporter#ABBREVIATION:DcuB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4123) or (b4138)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="3" />
                    <speciesReference species="M_succ_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCCt2b" name="Succinate efflux via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCCt2b</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[c] + succ[c] --&gt; h[e] + succ[e]</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0621#ABBREVIATION:dcuC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dicarboxylate transporter#ABBREVIATION:DcuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0621)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_succ_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCD1i" name="succinate dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCD1i</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.3.99.1</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : fad + succ --&gt; fadh2 + fum</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - made an irreversible version of the SUCD1 reaction</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0721#ABBREVIATION:sdhC#</html:p>
                    <html:p>LOCUS:b0722#ABBREVIATION:sdhD#</html:p>
                    <html:p>LOCUS:b0723#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>LOCUS:b0724#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:succinate dehydrogenase#ABBREVIATION:Sdh#</html:p>
                    <html:p>GENE ASSOCIATION: (b0722 and b0721 and b0723 and b0724)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fadh2_c" />
                    <speciesReference species="M_fum_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCD4" name="succinate dehyrdogenase">
                <notes>
                    <html:p>Abbreviation: R_SUCD4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : fadh2 + q8 &lt;==&gt; fad + q8h2</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0721#ABBREVIATION:sdhC#</html:p>
                    <html:p>LOCUS:b0722#ABBREVIATION:sdhD#</html:p>
                    <html:p>LOCUS:b0723#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>LOCUS:b0724#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:succinate dehydrogenase#ABBREVIATION:Sdh#</html:p>
                    <html:p>GENE ASSOCIATION: (b0722 and b0721 and b0723 and b0724)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fadh2_c" />
                    <speciesReference species="M_q8_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fad_c" />
                    <speciesReference species="M_q8h2_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCFUMt" name="succinate:fumarate antiporter">
                <notes>
                    <html:p>Abbreviation: R_SUCFUMt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: fum[e] + succ[c] &lt;==&gt; fum[c] + succ[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0621#ABBREVIATION:dcuC#</html:p>
                    <html:p>LOCUS:b4123#ABBREVIATION:dcuB#</html:p>
                    <html:p>LOCUS:b4138#ABBREVIATION:dcuA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Anaerobic C4-dicarboxylate transporter protein#ABBREVIATION:DcuA#</html:p>
                    <html:p>NAME:anaerobic C4-dicarboxylate transporter#ABBREVIATION:DcuB#</html:p>
                    <html:p>NAME:dicarboxylate transporter#ABBREVIATION:DcuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b4138) or (b0621) or (b4123)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fum_e" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_fum_c" />
                    <speciesReference species="M_succ_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCOAS" name="succinyl-CoA synthetase (ADP-forming)">
                <notes>
                    <html:p>Abbreviation: R_SUCOAS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.2.1.5</html:p>
                    <html:p>SUBSYSTEM: Citric Acid Cycle</html:p>
                    <html:p>Equation: [c] : atp + coa + succ &lt;==&gt; adp + pi + succoa</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0728#ABBREVIATION:sucC#ECNUMBERS:6.2.1.5#</html:p>
                    <html:p>LOCUS:b0729#ABBREVIATION:sucD#ECNUMBERS:6.2.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:succinyl-CoA synthetase beta chain#ABBREVIATION:SucC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0728 and b0729)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_succ_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_succoa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SUCpts" name="sucrose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SUCpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: pep[c] + sucr[e] --&gt; pyr[c] + suc6p[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2417#ABBREVIATION:crr#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b2429#ABBREVIATION:murP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, Glucose/Trehalose/Maltose IIA#ABBREVIATION:Crr#</html:p>
                    <html:p>NAME:Putative PTS, sucrose IIBC#ABBREVIATION:ScrA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2417) and (b2429) and (b2416)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_sucr_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_suc6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SULR" name="sulfite reductase (NADPH2)">
                <notes>
                    <html:p>Abbreviation: R_SULR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.8.2.2</html:p>
                    <html:p>SUBSYSTEM: Cysteine Metabolism</html:p>
                    <html:p>Equation: [c] : (3) h2o + h2s + (3) nadp &lt;==&gt; (5) h + (3) nadph + so3</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- EC number is 1.8.1.2?
</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2763#ABBREVIATION:cysI#ECNUMBERS:1.8.1.2#</html:p>
                    <html:p>LOCUS:b2764#ABBREVIATION:cysJ#ECNUMBERS:1.8.1.2,-!-,1.6.8.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:sulfite reductase#ABBREVIATION:CysIJ#</html:p>
                    <html:p>GENE ASSOCIATION: (b2764 and b2763)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" stoichiometry="3" />
                    <speciesReference species="M_h2s_c" />
                    <speciesReference species="M_nadp_c" stoichiometry="3" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="5" />
                    <speciesReference species="M_nadph_c" stoichiometry="3" />
                    <speciesReference species="M_so3_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_SULabc" name="sulfate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_SULabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + so4[e] --&gt; adp[c] + h[c] + pi[c] + so4[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2413#ABBREVIATION:cysZ#</html:p>
                    <html:p>LOCUS:b2422#ABBREVIATION:cysA#ECNUMBERS:3.6.3.25#</html:p>
                    <html:p>LOCUS:b2423#ABBREVIATION:cysW#</html:p>
                    <html:p>LOCUS:b2424#ABBREVIATION:cysU#</html:p>
                    <html:p>LOCUS:b2425#ABBREVIATION:cysP#</html:p>
                    <html:p>LOCUS:b3917#ABBREVIATION:sbp#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, sulfate (atp)#ABBREVIATION:CysA#</html:p>
                    <html:p>NAME:ABC, sulfate (membrane)#ABBREVIATION:CysW#</html:p>
                    <html:p>NAME:ABC, sulfate (membrate)#ABBREVIATION:CysU#</html:p>
                    <html:p>NAME:predicted sulfate transport protein#ABBREVIATION:CysZ#</html:p>
                    <html:p>NAME:ABC, sulfate (periplasm)#ABBREVIATION:Sbp#</html:p>
                    <html:p>NAME:ABC thiosulfate transporter (peri_bind)#ABBREVIATION:CysP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2422) and (b2425) and (b2423) and (b2424) or (b2422) and (b2423) and (b2424) and (b2413) and (b3917)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_so4_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_so4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TAGURr" name="tagaturonate reductase">
                <notes>
                    <html:p>Abbreviation: R_TAGURr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.58</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : altrn + nad &lt;==&gt; h + nadh + tagur</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR- reversible form of TAGUR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1521#ABBREVIATION:uxaB#ECNUMBERS:1.1.1.58#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:altronate oxidoreductase#ABBREVIATION:UxaB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1521)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_altrn_c" />
                    <speciesReference species="M_nad_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_tagur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TALA" name="transaldolase">
                <notes>
                    <html:p>Abbreviation: R_TALA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.2.1.2</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : g3p + s7p &lt;==&gt; e4p + f6p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0008#ABBREVIATION:talB#ECNUMBERS:2.2.1.2#</html:p>
                    <html:p>LOCUS:b2464#ABBREVIATION:talA#ECNUMBERS:2.2.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:transaldolase B#ABBREVIATION:TalB#</html:p>
                    <html:p>NAME:transaldolase A#ABBREVIATION:TalA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0008) or (b2464)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_s7p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_e4p_c" />
                    <speciesReference species="M_f6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TARTD" name="L(+)-tartrate dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TARTD</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 4.2.1.32</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : tartr-L --&gt; h2o + oaa</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3061#ABBREVIATION:ttdA#ECNUMBERS:4.2.1.32#</html:p>
                    <html:p>LOCUS:b3062#ABBREVIATION:ttdB#ECNUMBERS:4.2.1.32#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-tartrate dehydratase#ABBREVIATION:TtdAB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3062 and b3061)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tartr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_oaa_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TARTRt7" name="Tartrate/succinate antiporter">
                <notes>
                    <html:p>Abbreviation: R_TARTRt7</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: succ[c] + tartr-L[e] &lt;==&gt; succ[e] + tartr-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3063#ABBREVIATION:ygjE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative tartrate/succinate antiporter, DASS#ABBREVIATION:YgjE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3063)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_succ_c" />
                    <speciesReference species="M_tartr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_succ_e" />
                    <speciesReference species="M_tartr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TAUDO" name="Taurine dioxygenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TAUDO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.14.11.17</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : akg + o2 + taur --&gt; aacald + co2 + h + so3 + succ</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0368#ABBREVIATION:tauD#ECNUMBERS:1.14.11.17#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:taurine dioxygenase#ABBREVIATION:TauD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0368)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_o2_c" />
                    <speciesReference species="M_taur_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_aacald_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_so3_c" />
                    <speciesReference species="M_succ_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TAURabc" name="taurine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TAURabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + taur[e] --&gt; adp[c] + h[c] + pi[c] + taur[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0365#ABBREVIATION:tauA#</html:p>
                    <html:p>LOCUS:b0366#ABBREVIATION:tauB#</html:p>
                    <html:p>LOCUS:b0367#ABBREVIATION:tauC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC taurine transporter (peri_bind)#ABBREVIATION:TauA#</html:p>
                    <html:p>NAME:ABC taurine transporter (atp_bind)#ABBREVIATION:TauB#</html:p>
                    <html:p>NAME:ABC taurine transporter (membrane)#ABBREVIATION:TauC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0365) and (b0367) and (b0366)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_taur_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_taur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDPADGAT" name="dTDP-4-amino-4,6-dideoxy-D-glucose acetyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDPADGAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : accoa + dtdp4addg --&gt; coa + dtdp4aaddg + h</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3790#ABBREVIATION:rffC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-4-amino-4,6-dideoxy-D-glucose acetyltransferase#ABBREVIATION:WecD#</html:p>
                    <html:p>GENE ASSOCIATION: (b3790)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_accoa_c" />
                    <speciesReference species="M_dtdp4addg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_dtdp4aaddg_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDPAGTA" name="dTDP-4-amino-4,6-dideoxy-D-glucose transaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDPAGTA</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 2.6.1.33</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dtdp4d6dg + glu-L --&gt; akg + dtdp4addg</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3791#ABBREVIATION:rffA#ECNUMBERS:2.6.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-4-oxo-6-deoxy-D-glucose transaminase#ABBREVIATION:WecE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3791)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtdp4d6dg_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_dtdp4addg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDPDRE" name="dTDP-4-dehydrorhamnose 3,5-epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDPDRE</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 5.1.3.13</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dtdp4d6dg --&gt; dtdp4d6dm</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2038#ABBREVIATION:rfbC#ECNUMBERS:5.1.3.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-4,deoxyrhamnose 3,5 epimerase#ABBREVIATION:RfbC#</html:p>
                    <html:p>GENE ASSOCIATION: (b2038)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtdp4d6dg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtdp4d6dm_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDPDRR" name="dTDP-4-dehydrorhamnose reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDPDRR</html:p>
                    <html:p>Synonyms: _5</html:p>
                    <html:p>EC Number: 1.1.1.133</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dtdp4d6dm + h + nadph --&gt; dtdprmn + nadp</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2040#ABBREVIATION:rfbD#ECNUMBERS:1.1.1.133#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-rhamnose synthetase#ABBREVIATION:RfbD#</html:p>
                    <html:p>GENE ASSOCIATION: (b2040)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtdp4d6dm_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtdprmn_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDPGDH" name="dTDPglucose 4,6-dehydratase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDPGDH</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.2.1.46</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : dtdpglu --&gt; dtdp4d6dg + h2o</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2041#ABBREVIATION:rfbB#ECNUMBERS:4.2.1.46#</html:p>
                    <html:p>LOCUS:b3788#ABBREVIATION:rffG#ECNUMBERS:4.2.1.46#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:dTDP-glucose 4,6-dehydratase#ABBREVIATION:RffG#</html:p>
                    <html:p>NAME:dTDP-glucose 4,6 dehydratase#ABBREVIATION:RfbB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2041) or (b3788)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dtdpglu_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dtdp4d6dg_c" />
                    <speciesReference species="M_h2o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TDSK" name="Tetraacyldisaccharide 4'kinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TDSK</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.7.1.130</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + lipidAds --&gt; adp + h + lipidA</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0915#ABBREVIATION:lpxK#ECNUMBERS:2.7.1.130#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tetraacyldisaccharide 4' kinase#ABBREVIATION:LpxK#</html:p>
                    <html:p>GENE ASSOCIATION: (b0915)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_lipidAds_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_lipidA_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TGBPA" name="Tagatose-bisphosphate aldolase">
                <notes>
                    <html:p>Abbreviation: R_TGBPA</html:p>
                    <html:p>Synonyms: _2</html:p>
                    <html:p>EC Number: 4.1.2.40</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : tagdp-D &lt;==&gt; dhap + g3p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2095#ABBREVIATION:gatZ#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>LOCUS:b2096#ABBREVIATION:gatY#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>LOCUS:b3132#ABBREVIATION:kbaZ#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>LOCUS:b3137#ABBREVIATION:kbaY#ECNUMBERS:4.1.2.40#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tagatose 6-phosphate aldolase I#ABBREVIATION:AgaZ#</html:p>
                    <html:p>NAME:tagatose 6-phosphate aldolase II#ABBREVIATION:GatZ#</html:p>
                    <html:p>GENE ASSOCIATION: (b3137 and b3132) or (b2096 and b2095)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_tagdp_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhap_c" />
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THD2" name="NAD(P) transhydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THD2</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.6.1.1</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: (2) h[e] + nadh[c] + nadp[c] --&gt; (2) h[c] + nad[c] + nadph[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR - proton translocating form</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1602#ABBREVIATION:pntB#ECNUMBERS:1.6.1.2#</html:p>
                    <html:p>LOCUS:b1603#ABBREVIATION:pntA#ECNUMBERS:1.6.1.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:pyridine nucleotide transhydrogenase#ABBREVIATION:Pnt#</html:p>
                    <html:p>GENE ASSOCIATION: (b1602 and b1603)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" stoichiometry="2" />
                    <speciesReference species="M_nadh_c" />
                    <speciesReference species="M_nadp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_nadph_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THDPS" name="tetrahydrodipicolinate succinylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.117</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + succoa + thdp --&gt; coa + sl2a6o</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0166#ABBREVIATION:dapD#ECNUMBERS:2.3.1.117#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tetrahydrodipicolinate N-succinultransferase#ABBREVIATION:DapD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0166)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_succoa_c" />
                    <speciesReference species="M_thdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_coa_c" />
                    <speciesReference species="M_sl2a6o_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THMDt2r" name="thymidine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_THMDt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + thymd[e] &lt;==&gt; h[c] + thymd[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_thymd_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thymd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THMabc" name="thiamine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THMabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + thm[e] --&gt; adp[c] + h[c] + pi[c] + thm[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0066#ABBREVIATION:thiQ#</html:p>
                    <html:p>LOCUS:b0067#ABBREVIATION:thiP#</html:p>
                    <html:p>LOCUS:b0068#ABBREVIATION:tbpA#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC thiamine transporter (peri_bind)#ABBREVIATION:SfuA#</html:p>
                    <html:p>NAME:ABC thiamine transporter (membrane)#ABBREVIATION:SfuB#</html:p>
                    <html:p>NAME:ABC thiamine transporter (atp_bind)#ABBREVIATION:SfuC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0066) and (b0067) and (b0068)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_thm_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_thm_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRAr" name="Threonine Aldolase">
                <notes>
                    <html:p>Abbreviation: R_THRAr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.2.5</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : thr-L &lt;==&gt; acald + gly</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0870#ABBREVIATION:ltaE#ECNUMBERS:4.1.2.5#</html:p>
                    <html:p>LOCUS:b2551#ABBREVIATION:glyA#ECNUMBERS:2.1.2.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Serine Hydroxymethyltransferase#ABBREVIATION:GlyA#</html:p>
                    <html:p>NAME:Threonine aldolase#ABBREVIATION:LtaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0870) or (b2551)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_thr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_acald_c" />
                    <speciesReference species="M_gly_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRD" name="L-threonine dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THRD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.103</html:p>
                    <html:p>SUBSYSTEM: Glycine and Serine Metabolism</html:p>
                    <html:p>Equation: [c] : nad + thr-L --&gt; 2aobut + h + nadh</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>The product (L-2-amino-3-oxobutanoate) spontaneously deecarboxylates to amino acetone
See AOBUTDs</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3616#ABBREVIATION:tdh#ECNUMBERS:1.1.1.103#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Threonine 3-dehydrogenase#ABBREVIATION:Tdh#</html:p>
                    <html:p>GENE ASSOCIATION: (b3616)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_nad_c" />
                    <speciesReference species="M_thr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2aobut_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRD_L" name="L-threonine deaminase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THRD_L</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 4.3.1.19</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : thr-L --&gt; 2obut + nh4</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Previous EC number: 4.2.1.16. New EC number 4.3.1.19. Can&amp;apos;t enter this....</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1814#ABBREVIATION:sdaA#ECNUMBERS:4.3.1.17#</html:p>
                    <html:p>LOCUS:b2797#ABBREVIATION:sdaB#ECNUMBERS:4.3.1.17#</html:p>
                    <html:p>LOCUS:b3117#ABBREVIATION:tdcB#ECNUMBERS:4.3.1.19#</html:p>
                    <html:p>LOCUS:b3772#ABBREVIATION:ilvA#ECNUMBERS:4.3.1.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:threonine deaminase#ABBREVIATION:IlvA#</html:p>
                    <html:p>NAME:Serine deaminase I#ABBREVIATION:SdaAec#</html:p>
                    <html:p>NAME:Serine deaminase II#ABBREVIATION:SdaB#</html:p>
                    <html:p>NAME:Threonine dehydratase#ABBREVIATION:TdcB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3772) or (b3117) or (b2797) or (b1814)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_thr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2obut_c" />
                    <speciesReference species="M_nh4_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRS" name="threonine synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THRS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.3.1</html:p>
                    <html:p>SUBSYSTEM: Threonine and Lysine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + phom --&gt; pi + thr-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0004#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Threonine synthase#ABBREVIATION:ThrC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0004)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_phom_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_thr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRabc" name="L-threonine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THRabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + thr-L[e] --&gt; adp[c] + h[c] + pi[c] + thr-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3454#ABBREVIATION:livF#</html:p>
                    <html:p>LOCUS:b3455#ABBREVIATION:livG#</html:p>
                    <html:p>LOCUS:b3456#ABBREVIATION:livM#</html:p>
                    <html:p>LOCUS:b3457#ABBREVIATION:livH#</html:p>
                    <html:p>LOCUS:b3460#ABBREVIATION:livJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivJ#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivF#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivG#</html:p>
                    <html:p>NAME:ABC, branced chain AA (membrane)#ABBREVIATION:LivH#</html:p>
                    <html:p>NAME:ABC, branced chain AA #ABBREVIATION:LivM#</html:p>
                    <html:p>GENE ASSOCIATION: (b3455) and (b3457) and (b3460) and (b3454) and (b3456)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_thr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_thr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRt2r" name="L-threonine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_THRt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + thr-L[e] &lt;==&gt; h[c] + thr-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3116#ABBREVIATION:tdcC#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-threonine/L-serine proton symport#ABBREVIATION:TdcC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3116)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_thr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THRt4" name="L-threonine  via sodium symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THRt4</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: na1[e] + thr-L[e] --&gt; na1[c] + thr-L[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3089#ABBREVIATION:sstT#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:DAACS Na:serine/threonine symporter#ABBREVIATION:SstT#</html:p>
                    <html:p>GENE ASSOCIATION: (b3089)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_na1_e" />
                    <speciesReference species="M_thr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_na1_c" />
                    <speciesReference species="M_thr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_THZPSN" name="thiazole phosphate synthesis" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_THZPSN</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + cys-L + dxyl5p + tyr-L --&gt; 4hba + 4mpetz + ala-L + amp + co2 + h + h2o + ppi</html:p>
                    <html:p>Confidence Level: 2</html:p>
                    <html:p>JLR- added based on mechanisms proposed in Begley&amp;apos;s review (Arch Microbiol (1999) 171:293-300). Not sure about ala by-product guessed based on incorporating sulfur into biotin.</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0423#ABBREVIATION:thiI#</html:p>
                    <html:p>LOCUS:b2530#ABBREVIATION:iscS#ECNUMBERS:2.8.1.7#</html:p>
                    <html:p>LOCUS:b3990#ABBREVIATION:thiH#</html:p>
                    <html:p>LOCUS:b3991#ABBREVIATION:thiG#</html:p>
                    <html:p>LOCUS:b3992#ABBREVIATION:thiF#ECNUMBERS:2.7.7.-#</html:p>
                    <html:p>LOCUS:b4407#ABBREVIATION:thiS#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ThiS carries S from cys to thiazole-P#ABBREVIATION:ThiS#</html:p>
                    <html:p>NAME:adentylates ThiS so that S can be added to ThiS#ABBREVIATION:ThiFec#</html:p>
                    <html:p>NAME:Thiazole -P synthase#ABBREVIATION:ThiGH#</html:p>
                    <html:p>NAME:sulfur transfer protein#ABBREVIATION:ThiI#</html:p>
                    <html:p>NAME:cysteine desulfurase#ABBREVIATION:IscS#</html:p>
                    <html:p>GENE ASSOCIATION: (b3991 and b3990) and (b4407) and (b0423) and (b3992) and (b2530)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_cys_L_c" />
                    <speciesReference species="M_dxyl5p_c" />
                    <speciesReference species="M_tyr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_4hba_c" />
                    <speciesReference species="M_4mpetz_c" />
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_amp_c" />
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_ppi_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TKT1" name="transketolase">
                <notes>
                    <html:p>Abbreviation: R_TKT1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.2.1.1</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : r5p + xu5p-D &lt;==&gt; g3p + s7p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP
Two reactions for transketolase: TKT1 and TKT2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2465#ABBREVIATION:tktB#ECNUMBERS:2.2.1.1#</html:p>
                    <html:p>LOCUS:b2935#ABBREVIATION:tktA#ECNUMBERS:2.2.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:transketolase I#ABBREVIATION:TktA#</html:p>
                    <html:p>NAME:transketolase II#ABBREVIATION:TktB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2935) or (b2465)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_r5p_c" />
                    <speciesReference species="M_xu5p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_s7p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TKT2" name="transketolase">
                <notes>
                    <html:p>Abbreviation: R_TKT2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.2.1.1</html:p>
                    <html:p>SUBSYSTEM: Pentose Phosphate Pathway</html:p>
                    <html:p>Equation: [c] : e4p + xu5p-D &lt;==&gt; f6p + g3p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP
Two reactions for transketolase: TKT1 and TKT2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2465#ABBREVIATION:tktB#ECNUMBERS:2.2.1.1#</html:p>
                    <html:p>LOCUS:b2935#ABBREVIATION:tktA#ECNUMBERS:2.2.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:transketolase I#ABBREVIATION:TktA#</html:p>
                    <html:p>NAME:transketolase II#ABBREVIATION:TktB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2465) or (b2935)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_e4p_c" />
                    <speciesReference species="M_xu5p_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_f6p_c" />
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMAOR1" name="Trimethylamine N-oxide reductase (menaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMAOR1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : h + mql8 + tmao --&gt; h2o + mqn8 + tma</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0894#ABBREVIATION:dmsA#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0895#ABBREVIATION:dmsB#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0896#ABBREVIATION:dmsC#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anaerobic dimethyl sulfoxide reductase#ABBREVIATION:DmsABC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0894 and b0896 and b0895)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_tmao_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_tma_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMAOR1e" name="Trimethylamine N-oxide reductase (menaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMAOR1e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: h[e] + mql8[c] + tmao[e] --&gt; h2o[e] + mqn8[c] + tma[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0996#ABBREVIATION:torC#</html:p>
                    <html:p>LOCUS:b0997#ABBREVIATION:torA#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1872#ABBREVIATION:torZ#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1873#ABBREVIATION:torY#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorA#</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorZ#</html:p>
                    <html:p>NAME:cytochrome c-type in TMAO reductase system I#ABBREVIATION:TorC#</html:p>
                    <html:p>NAME:cytochrome c-type protein in TMAO reductase system III#ABBREVIATION:TorY#</html:p>
                    <html:p>GENE ASSOCIATION: (b0996) and (b0997) or (b1873) and (b1872)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_mql8_c" />
                    <speciesReference species="M_tmao_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_mqn8_c" />
                    <speciesReference species="M_tma_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMAOR2" name="Trimethylamine N-oxide reductase (demethylmenaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMAOR2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : 2dmmql8 + h + tmao --&gt; 2dmmq8 + h2o + tma</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0894#ABBREVIATION:dmsA#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0895#ABBREVIATION:dmsB#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>LOCUS:b0896#ABBREVIATION:dmsC#ECNUMBERS:1.8.99.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:anaerobic dimethyl sulfoxide reductase#ABBREVIATION:DmsABC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0894 and b0896 and b0895)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_tmao_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_tma_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMAOR2e" name="Trimethylamine N-oxide reductase (demethylmenaquinol 8)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMAOR2e</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: _2dmmql8[c] + h[e] + tmao[e] --&gt; 2dmmq8[c] + h2o[e] + tma[e]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0996#ABBREVIATION:torC#</html:p>
                    <html:p>LOCUS:b0997#ABBREVIATION:torA#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1872#ABBREVIATION:torZ#ECNUMBERS:1.6.6.9#</html:p>
                    <html:p>LOCUS:b1873#ABBREVIATION:torY#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorA#</html:p>
                    <html:p>NAME:trimethylamine N-oxide reductase#ABBREVIATION:TorZ#</html:p>
                    <html:p>NAME:cytochrome c-type in TMAO reductase system I#ABBREVIATION:TorC#</html:p>
                    <html:p>NAME:cytochrome c-type protein in TMAO reductase system III#ABBREVIATION:TorY#</html:p>
                    <html:p>GENE ASSOCIATION: (b0996) and (b0997) or (b1873) and (b1872)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2dmmql8_c" />
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_tmao_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dmmq8_c" />
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_tma_e" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMDK1" name="thymidine kinase (ATP:thymidine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMDK1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.21</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + thymd --&gt; adp + dtmp + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1238#ABBREVIATION:tdk#ECNUMBERS:2.7.1.21#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thimidine kinase#ABBREVIATION:Tdk#</html:p>
                    <html:p>GENE ASSOCIATION: (b1238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_thymd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dtmp_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMDPP" name="thymidine phosphorylase">
                <notes>
                    <html:p>Abbreviation: R_TMDPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.4</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : pi + thymd &lt;==&gt; 2dr1p + thym</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4382#ABBREVIATION:deoA#ECNUMBERS:2.4.2.4#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thymidine phosphorylase#ABBREVIATION:DeoA#</html:p>
                    <html:p>GENE ASSOCIATION: (b4382)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_thymd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_2dr1p_c" />
                    <speciesReference species="M_thym_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMDS" name="thymidylate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMDS</html:p>
                    <html:p>Synonyms: _4</html:p>
                    <html:p>EC Number: 2.1.1.45</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : dump + mlthf --&gt; dhf + dtmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2827#ABBREVIATION:thyA#ECNUMBERS:2.1.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thymidylate synthetase#ABBREVIATION:ThyA#</html:p>
                    <html:p>GENE ASSOCIATION: (b2827)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dump_c" />
                    <speciesReference species="M_mlthf_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_dhf_c" />
                    <speciesReference species="M_dtmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMKr" name="thiamine kinase">
                <notes>
                    <html:p>Abbreviation: R_TMKr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.89</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + thm &lt;==&gt; adp + h + thmmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_thm_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_thmmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMPKr" name="thiamine-phosphate kinase">
                <notes>
                    <html:p>Abbreviation: R_TMPKr</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.4.16</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + thmmp &lt;==&gt; adp + thmpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0417#ABBREVIATION:thiL#ECNUMBERS:2.7.4.16#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thiamin-monophosphate kinase#ABBREVIATION:ThiL#</html:p>
                    <html:p>GENE ASSOCIATION: (b0417)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_thmmp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_thmpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TMPPP" name="thiamine-phosphate diphosphorylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TMPPP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.3</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : 2mahmp + 4mpetz + h --&gt; ppi + thmmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3993#ABBREVIATION:thiE#ECNUMBERS:2.5.1.3#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:thiamin phosphate synthase#ABBREVIATION:ThiE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3993)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2mahmp_c" />
                    <speciesReference species="M_4mpetz_c" />
                    <speciesReference species="M_h_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_thmmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TPI" name="triose-phosphate isomerase">
                <notes>
                    <html:p>Abbreviation: R_TPI</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.1</html:p>
                    <html:p>SUBSYSTEM: Glycolysis/Gluconeogenesis</html:p>
                    <html:p>Equation: [c] : dhap &lt;==&gt; g3p</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>SMP</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3919#ABBREVIATION:tpiA#ECNUMBERS:5.3.1.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:triosephosphate isomerase#ABBREVIATION:Tpi#</html:p>
                    <html:p>GENE ASSOCIATION: (b3919)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_dhap_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRDR" name="thioredoxin reductase (NADPH)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRDR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.8.1.9</html:p>
                    <html:p>SUBSYSTEM: Oxidative Phosphorylation</html:p>
                    <html:p>Equation: [c] : h + nadph + trdox --&gt; nadp + trdrd</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0888#ABBREVIATION:trxB#ECNUMBERS:1.8.1.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Thioredoxin reductase#ABBREVIATION:TrxB#</html:p>
                    <html:p>GENE ASSOCIATION: (b0888)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_trdox_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_trdrd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRE6PH" name="trehalose-6-phosphate hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRE6PH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.1.93</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + tre6p --&gt; g6p + glc-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4239#ABBREVIATION:treC#ECNUMBERS:3.2.1.93#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trehalose-6-phosphate hydrolase#ABBREVIATION:TreC#</html:p>
                    <html:p>GENE ASSOCIATION: (b4239)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_tre6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_glc_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRE6PP" name="trehalose-phosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRE6PP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.1.3.12</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + tre6p --&gt; pi + tre</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>TRE6PS is a part of TRE6PS/TRE6PP complex
IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1897#ABBREVIATION:otsB#ECNUMBERS:3.1.3.12#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trehalose-6-phosphate phosphatase#ABBREVIATION:OtsB#</html:p>
                    <html:p>GENE ASSOCIATION: (b1897)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_tre6p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_tre_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRE6PS" name="alpha,alpha-trehalose-phosphate synthase (UDP-forming)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRE6PS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.1.15</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : g6p + udpg --&gt; h + tre6p + udp</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>TRE6PS is a part of TRE6PS/TRE6PP complex
IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1896#ABBREVIATION:otsA#ECNUMBERS:2.4.1.15#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trehalose-6-phosphate synthase#ABBREVIATION:OtsA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1896)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_g6p_c" />
                    <speciesReference species="M_udpg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_tre6p_c" />
                    <speciesReference species="M_udp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TREH" name="alpha,alpha-trehalase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TREH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.1.28</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + tre --&gt; (2) glc-D</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>IF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3519#ABBREVIATION:treF#ECNUMBERS:3.2.1.28#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Trehalase#ABBREVIATION:TreF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3519)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_tre_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TREHe" name="alpha,alpha-trehalase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TREHe</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.2.1.28</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [e] : h2o + tre --&gt; (2) glc-D</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1197#ABBREVIATION:treA#ECNUMBERS:3.2.1.28#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:trehalase, periplasmic#ABBREVIATION:TreA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1197)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_e" />
                    <speciesReference species="M_tre_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_e" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TREpts" name="trehalose transport via PEP:Pyr PTS" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TREpts</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: pep[c] + tre[e] --&gt; pyr[c] + tre6p[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2415#ABBREVIATION:ptsH#</html:p>
                    <html:p>LOCUS:b2416#ABBREVIATION:ptsI#ECNUMBERS:2.7.3.9#</html:p>
                    <html:p>LOCUS:b2417#ABBREVIATION:crr#ECNUMBERS:2.7.1.69#</html:p>
                    <html:p>LOCUS:b4240#ABBREVIATION:treB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Hpr protein involved in PTS transport systems#ABBREVIATION:PtsH#</html:p>
                    <html:p>NAME:Enzyme I from PTS transport systems#ABBREVIATION:PtsI#</html:p>
                    <html:p>NAME:PTS, Glucose/Trehalose/Maltose IIA#ABBREVIATION:Crr#</html:p>
                    <html:p>NAME:PTS, trehalose IIBC#ABBREVIATION:TreB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2415) and (b2417) and (b2416) and (b4240)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_tre_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_tre6p_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRPAS2" name="Tryptophanase (L-tryptophan)">
                <notes>
                    <html:p>Abbreviation: R_TRPAS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.99.1</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : h2o + trp-L &lt;==&gt; indole + nh4 + pyr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3708#ABBREVIATION:tnaA#ECNUMBERS:4.1.99.1#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tryptophan deaminase#ABBREVIATION:TnaA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3708)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trp_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_indole_c" />
                    <speciesReference species="M_nh4_c" />
                    <speciesReference species="M_pyr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRPS1" name="tryptophan synthase (indoleglycerol phosphate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRPS1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 3ig3p + ser-L --&gt; g3p + h2o + trp-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1260#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>LOCUS:b1261#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tryptophan synthase#ABBREVIATION:TrpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1260 and b1261)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3ig3p_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trp_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRPS2" name="tryptophan synthase (indole)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRPS2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : indole + ser-L --&gt; h2o + trp-L</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>A pyridoxal-phosphate protein.
 Also catalyses the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate (the latter reaction was listed formerly as EC 4.1.2.8). </html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1260#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>LOCUS:b1261#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tryptophan synthase#ABBREVIATION:TrpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1260 and b1261)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_indole_c" />
                    <speciesReference species="M_ser_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_trp_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRPS3" name="tryptophan synthase (indoleglycerol phosphate)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRPS3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.20</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : 3ig3p --&gt; g3p + indole</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1260#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>LOCUS:b1261#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tryptophan synthase#ABBREVIATION:TrpA#</html:p>
                    <html:p>GENE ASSOCIATION: (b1260 and b1261)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3ig3p_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g3p_c" />
                    <speciesReference species="M_indole_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRPt2r" name="L-tryptophan reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_TRPt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + trp-L[e] &lt;==&gt; h[c] + trp-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0112#ABBREVIATION:aroP#</html:p>
                    <html:p>LOCUS:b3161#ABBREVIATION:mtr#</html:p>
                    <html:p>LOCUS:b3709#ABBREVIATION:tnaB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Tryptophan proton symporter#ABBREVIATION:TnaB#</html:p>
                    <html:p>NAME:APC, aromatic AA proton symporter#ABBREVIATION:AroP#</html:p>
                    <html:p>NAME:HAAP, tryptophan transport#ABBREVIATION:Mtr#</html:p>
                    <html:p>GENE ASSOCIATION: (b0112) or (b3709) or (b3161)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_trp_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_trp_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TRSAR" name="tartronate semialdehyde reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TRSAR</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 1.1.1.60</html:p>
                    <html:p>SUBSYSTEM: Glyoxylate Metabolism</html:p>
                    <html:p>Equation: [c] : 2h3oppan + h + nadh --&gt; glyc-R + nad</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0509#ABBREVIATION:glxR#ECNUMBERS:1.1.1.60#</html:p>
                    <html:p>LOCUS:b3125#ABBREVIATION:garR#ECNUMBERS:1.1.1.60#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tartronate semialdehyde reductase#ABBREVIATION:GarR#</html:p>
                    <html:p>NAME:tartonate semialdehyde reductase#ABBREVIATION:GlxR#</html:p>
                    <html:p>GENE ASSOCIATION: (b3125) or (b0509)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2h3oppan_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadh_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glyc_R_c" />
                    <speciesReference species="M_nad_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TSULabc" name="thiosulfate transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TSULabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + tsul[e] --&gt; adp[c] + h[c] + pi[c] + tsul[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2422#ABBREVIATION:cysA#ECNUMBERS:3.6.3.25#</html:p>
                    <html:p>LOCUS:b2423#ABBREVIATION:cysW#</html:p>
                    <html:p>LOCUS:b2424#ABBREVIATION:cysU#</html:p>
                    <html:p>LOCUS:b2425#ABBREVIATION:cysP#</html:p>
                    <html:p>LOCUS:b3917#ABBREVIATION:sbp#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, sulfate (atp)#ABBREVIATION:CysA#</html:p>
                    <html:p>NAME:ABC, sulfate (membrane)#ABBREVIATION:CysW#</html:p>
                    <html:p>NAME:ABC, sulfate (membrate)#ABBREVIATION:CysU#</html:p>
                    <html:p>NAME:ABC, sulfate (periplasm)#ABBREVIATION:Sbp#</html:p>
                    <html:p>NAME:ABC thiosulfate transporter (peri_bind)#ABBREVIATION:CysP#</html:p>
                    <html:p>GENE ASSOCIATION: (b2422) and (b2423) and (b3917) and (b2424) or (b2422) and (b2425) and (b2423) and (b2424)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_tsul_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_tsul_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TTDCAt2" name="Tetradecanoate transport via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_TTDCAt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + ttdca[e] --&gt; h[c] + ttdca[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2344#ABBREVIATION:fadL#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:long chain fatty acid transporter#ABBREVIATION:FadL#</html:p>
                    <html:p>GENE ASSOCIATION: (b2344)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ttdca_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ttdca_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TYRTA" name="tyrosine transaminase">
                <notes>
                    <html:p>Abbreviation: R_TYRTA</html:p>
                    <html:p>Synonyms: _13</html:p>
                    <html:p>EC Number: 2.6.1.5</html:p>
                    <html:p>SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism</html:p>
                    <html:p>Equation: [c] : akg + tyr-L &lt;==&gt; 34hpp + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0928#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1#</html:p>
                    <html:p>LOCUS:b4054#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:aspartate aminotransferase#ABBREVIATION:AspC#</html:p>
                    <html:p>NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB#</html:p>
                    <html:p>GENE ASSOCIATION: (b4054) or (b0928)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_tyr_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_34hpp_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_TYRt2r" name="L-tyrosine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_TYRt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + tyr-L[e] &lt;==&gt; h[c] + tyr-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD	</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0112#ABBREVIATION:aroP#</html:p>
                    <html:p>LOCUS:b0576#ABBREVIATION:pheP#</html:p>
                    <html:p>LOCUS:b1907#ABBREVIATION:tyrP#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:tyrosine proton symporter#ABBREVIATION:TyrP#</html:p>
                    <html:p>NAME:APC, aromatic AA proton symporter#ABBREVIATION:AroP#</html:p>
                    <html:p>NAME:APC, phenylalanine H symport#ABBREVIATION:PheP#</html:p>
                    <html:p>GENE ASSOCIATION: (b0576) or (b0112) or (b1907)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_tyr_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_tyr_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_U23GAAT" name="UDP-3-O-(3-hydroxymyristoyl)glucosamine acyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_U23GAAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : 3hmrsACP + u3hga --&gt; ACP + h + u23ga</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 1042</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0179#ABBREVIATION:lpxD#ECNUMBERS:2.3.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-3-0-(3-hydroxymyristoyl) glucosamine N-acyltransferase#ABBREVIATION:LpxD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0179)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hmrsACP_c" />
                    <speciesReference species="M_u3hga_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_u23ga_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAAGDS" name="UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAAGDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.13</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : 26dap-M + atp + uamag --&gt; adp + h + pi + ugmd</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0085#ABBREVIATION:murE#ECNUMBERS:6.3.2.13#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylmuramoxylalanyl-D-glutamate 2,6-diaminopimelate ligase#ABBREVIATION:MurEec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0085)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_26dap_M_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_uamag_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ugmd_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UACMAMO" name="UDP-N-acetyl-D-mannosamine oxidoreductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UACMAMO</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (2) nad + uacmam --&gt; (3) h + (2) nadh + uacmamu</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR (Kegg rxn R03317)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3787#ABBREVIATION:rffD#ECNUMBERS:1.1.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetyl-D-mannosaminuronate dehydrogenase#ABBREVIATION:WecC#</html:p>
                    <html:p>GENE ASSOCIATION: (b3787)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" stoichiometry="2" />
                    <speciesReference species="M_uacmam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_nadh_c" stoichiometry="2" />
                    <speciesReference species="M_uacmamu_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAG2Ei" name="UDP-N-acetylglucosamine 2-epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAG2Ei</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.3.14</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : uacgam --&gt; uacmam</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3786#ABBREVIATION:rffE#ECNUMBERS:5.1.3.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetyl glucosamine 2-epimerase#ABBREVIATION:WecB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3786)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uacgam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_uacmam_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAGAAT" name="UDP-N-acetylglucosamine acyltransferase">
                <notes>
                    <html:p>Abbreviation: R_UAGAAT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.3.1.129</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : 3hmrsACP + uacgam &lt;==&gt; ACP + u3aga</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- NH page 1041</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0181#ABBREVIATION:lpxA#ECNUMBERS:2.3.1.129#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylglycosamine acyltransferase#ABBREVIATION:LpxA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0181)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3hmrsACP_c" />
                    <speciesReference species="M_uacgam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ACP_c" />
                    <speciesReference species="M_u3aga_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAGCVT" name="UDP-N-acetylglucosamine 1-carboxyvinyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAGCVT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.5.1.7</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : pep + uacgam --&gt; pi + uaccg</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3189#ABBREVIATION:murA#ECNUMBERS:2.5.1.7#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylglucosamine-enolpyruvate transferase#ABBREVIATION:MurA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3189)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_pep_c" />
                    <speciesReference species="M_uacgam_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_uaccg_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAGDP" name="UDP-N-acetylglucosamine diphosphorylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAGDP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.23</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : acgam1p + h + utp --&gt; ppi + uacgam</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3730#ABBREVIATION:glmU#ECNUMBERS:2.7.7.23#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglucosamine-1-phosphate-uridyltransferase#ABBREVIATION:GlmUec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3730)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_acgam1p_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_utp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_uacgam_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAGPT3" name="UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAGPT3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : uacgam + uagmda --&gt; h + uaagmda + udp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>No exact EC number yet: EC 2.4.1.- catalyzed by murG gene in Bacillus subtilis
Also found in H. pylori.  Ref: Mendz pg 161 (tv)</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0090#ABBREVIATION:murG#ECNUMBERS:2.4.1.227#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:N-acetylglucosamine transferase#ABBREVIATION:MurGec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0090)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_uacgam_c" />
                    <speciesReference species="M_uagmda_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_uaagmda_c" />
                    <speciesReference species="M_udp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAMAGS" name="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAMAGS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.9</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : atp + glu-D + uama --&gt; adp + h + pi + uamag</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0088#ABBREVIATION:murD#ECNUMBERS:6.3.2.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylmuramoylalanine-D-glutamate ligase#ABBREVIATION:MurD#</html:p>
                    <html:p>GENE ASSOCIATION: (b0088)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_glu_D_c" />
                    <speciesReference species="M_uama_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_uamag_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAMAS" name="UDP-N-acetylmuramoyl-L-alanine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAMAS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.8</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : ala-L + atp + uamr --&gt; adp + h + pi + uama</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0091#ABBREVIATION:murC#ECNUMBERS:6.3.2.8#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylmuramate-alanine ligase#ABBREVIATION:MurC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0091)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_ala_L_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_uamr_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_uama_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UAPGR" name="UDP-N-acetylenolpyruvoylglucosamine reductase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UAPGR</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 1.1.1.158</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h + nadph + uaccg --&gt; nadp + uamr</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3972#ABBREVIATION:murB#ECNUMBERS:1.1.1.158#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-N-acetylenolpyruvoylglycosamine reductase#ABBREVIATION:MurB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3972)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_nadph_c" />
                    <speciesReference species="M_uaccg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_nadp_c" />
                    <speciesReference species="M_uamr_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UDCPDP" name="undecaprenyl-diphosphatase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UDCPDP</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.6.1.27</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + udcpdp --&gt; h + pi + udcpp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_udcpdp_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_udcpp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UDCPDPS" name="Undecaprenyl diphosphate synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UDCPDPS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : frdp + (8) ipdp --&gt; (8) ppi + udcpdp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0174#ABBREVIATION:ispU#ECNUMBERS:2.5.1.31#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Undecaprenyl diphosphate synthase#ABBREVIATION:UppS#</html:p>
                    <html:p>GENE ASSOCIATION: (b0174)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_frdp_c" />
                    <speciesReference species="M_ipdp_c" stoichiometry="8" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" stoichiometry="8" />
                    <speciesReference species="M_udcpdp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UDPG4E" name="UDPglucose 4-epimerase">
                <notes>
                    <html:p>Abbreviation: R_UDPG4E</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.1.3.2</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : udpg &lt;==&gt; udpgal</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0759#ABBREVIATION:galE#ECNUMBERS:5.1.3.2#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-glucose 4-epimerase#ABBREVIATION:GalE#</html:p>
                    <html:p>GENE ASSOCIATION: (b0759)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_udpg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_udpgal_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UDPGALM" name="UDPgalactopyranose mutase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UDPGALM</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.4.99.9</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : udpgal --&gt; udpgalfur</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2036#ABBREVIATION:glf#ECNUMBERS:5.4.99.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-galactropyranose mutase#ABBREVIATION:Glf#</html:p>
                    <html:p>GENE ASSOCIATION: (b2036)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_udpgal_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_udpgalfur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UDPGD" name="UDPglucose 6-dehydrogenase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UDPGD</html:p>
                    <html:p>Synonyms: _9</html:p>
                    <html:p>EC Number: 1.1.1.22</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + (2) nad + udpg --&gt; (3) h + (2) nadh + udpglcur</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2028#ABBREVIATION:ugd#ECNUMBERS:1.1.1.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-glucose 6-dehydrogenase#ABBREVIATION:Ugd#</html:p>
                    <html:p>GENE ASSOCIATION: (b2028)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_nad_c" stoichiometry="2" />
                    <speciesReference species="M_udpg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="3" />
                    <speciesReference species="M_nadh_c" stoichiometry="2" />
                    <speciesReference species="M_udpglcur_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UGLT" name="UDPglucose--hexose-1-phosphate uridylyltransferase">
                <notes>
                    <html:p>Abbreviation: R_UGLT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.7.12</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : gal1p + udpg &lt;==&gt; g1p + udpgal</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0758#ABBREVIATION:galT#ECNUMBERS:2.7.7.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:galactose-1-phosphate uridylyltransferase#ABBREVIATION:GalT#</html:p>
                    <html:p>GENE ASSOCIATION: (b0758)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gal1p_c" />
                    <speciesReference species="M_udpg_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_g1p_c" />
                    <speciesReference species="M_udpgal_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UGLYCH" name="Ureidoglycolate hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UGLYCH</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 3.5.3.19</html:p>
                    <html:p>SUBSYSTEM: Nitrogen Metabolism</html:p>
                    <html:p>Equation: [c] : (2) h + h2o + urdglyc --&gt; co2 + glx + (2) nh4</html:p>
                    <html:p>Confidence Level: 3</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0505#ABBREVIATION:allA#ECNUMBERS:3.5.3.19#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ureidoglycolate hydrolase#ABBREVIATION:AllA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0505)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_urdglyc_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" />
                    <speciesReference species="M_glx_c" />
                    <speciesReference species="M_nh4_c" stoichiometry="2" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UGMDDS" name="UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UGMDDS</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 6.3.2.15</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : alaala + atp + ugmd --&gt; adp + h + pi + ugmda</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0086#ABBREVIATION:murF#ECNUMBERS:6.3.2.10#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-alanine:D-alanine-adding enzme#ABBREVIATION:MurFec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0086)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_alaala_c" />
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ugmd_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_ugmda_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UHGADA" name="UDP-3-O-acetylglucosamine deacetylase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UHGADA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + u3aga --&gt; ac + u3hga</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tc</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0096#ABBREVIATION:lpxC#ECNUMBERS:3.5.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:UDP-3-O-acyl-N-acetylglucosamine deacetylase#ABBREVIATION:LpxC#</html:p>
                    <html:p>GENE ASSOCIATION: (b0096)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_u3aga_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ac_c" />
                    <speciesReference species="M_u3hga_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UMPK" name="UMP kinase">
                <notes>
                    <html:p>Abbreviation: R_UMPK</html:p>
                    <html:p>Synonyms: _9</html:p>
                    <html:p>EC Number: 2.7.4.14</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + ump &lt;==&gt; adp + udp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0171#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-#</html:p>
                    <html:p>LOCUS:b0910#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk#</html:p>
                    <html:p>NAME:uridylate kinase#ABBREVIATION:PyrHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0171) or (b0910)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_ump_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_udp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UNK3" name="_2-keto-4-methylthiobutyrate transamination" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UNK3</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Arginine and Proline Metabolism</html:p>
                    <html:p>Equation: [c] : 2kmb + glu-L --&gt; akg + met-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_2kmb_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_met_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UPP3MT" name="uroporphyrinogen methyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UPP3MT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.1.1.107</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (2) amet + uppg3 --&gt; (2) ahcys + dscl + h</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>See also SHCHD and SHCHF</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3368#ABBREVIATION:cysG#ECNUMBERS:2.1.1.107,-!-,4.99.1.-,-!-,1.-#</html:p>
                    <html:p>LOCUS:b3803#ABBREVIATION:hemX#ECNUMBERS:2.1.1.107#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uroporphyrinogen II methylase#ABBREVIATION:HemX#</html:p>
                    <html:p>NAME:siroheme synthase#ABBREVIATION:CysG#</html:p>
                    <html:p>GENE ASSOCIATION: (b3803) or (b3368)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_amet_c" stoichiometry="2" />
                    <speciesReference species="M_uppg3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ahcys_c" stoichiometry="2" />
                    <speciesReference species="M_dscl_c" />
                    <speciesReference species="M_h_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UPP3S" name="uroporphyrinogen-III synthase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UPP3S</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.2.1.75</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : hmbil --&gt; h2o + uppg3</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3804#ABBREVIATION:hemD#ECNUMBERS:4.2.1.75#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Uroporphyrinogen III synthase#ABBREVIATION:HemDec#</html:p>
                    <html:p>GENE ASSOCIATION: (b3804)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_hmbil_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_uppg3_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UPPDC1" name="uroporphyrinogen decarboxylase (uroporphyrinogen III)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UPPDC1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 4.1.1.37</html:p>
                    <html:p>SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis</html:p>
                    <html:p>Equation: [c] : (4) h + uppg3 --&gt; (4) co2 + cpppg3</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Acts on a number of porphyrinogens</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3997#ABBREVIATION:hemE#ECNUMBERS:4.1.1.37#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Uroporphyrinogen decarboxylase#ABBREVIATION:HemE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3997)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_c" stoichiometry="4" />
                    <speciesReference species="M_uppg3_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_co2_c" stoichiometry="4" />
                    <speciesReference species="M_cpppg3_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UPPRT" name="uracil phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_UPPRT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.9</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : prpp + ura --&gt; ppi + ump</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2498#ABBREVIATION:upp#ECNUMBERS:2.4.2.9#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Uracil phosphoribosyltransferase#ABBREVIATION:Upp#</html:p>
                    <html:p>GENE ASSOCIATION: (b2498)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_prpp_c" />
                    <speciesReference species="M_ura_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_URAt2r" name="uracil transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_URAt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: h[e] + ura[e] &lt;==&gt; h[c] + ura[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b1006#ABBREVIATION:ycdG#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative uracil transporter, NCS2#ABBREVIATION:YcdG#</html:p>
                    <html:p>GENE ASSOCIATION: (b1006)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_ura_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ura_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_UREAt" name="Urea transport via facilitate diffusion">
                <notes>
                    <html:p>Abbreviation: R_UREAt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: urea[e] &lt;==&gt; urea[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3927#ABBREVIATION:glpF#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF#</html:p>
                    <html:p>GENE ASSOCIATION: (b3927)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_urea_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_urea_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_URIDK2r" name="uridylate kinase (dUMP)">
                <notes>
                    <html:p>Abbreviation: R_URIDK2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : atp + dump &lt;==&gt; adp + dudp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR- reversible form of URIDK2</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0171#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uridylate kinase#ABBREVIATION:PyrHec#</html:p>
                    <html:p>GENE ASSOCIATION: (b0171)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_dump_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_dudp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_URIK2" name="uridine kinase (GTP:Uridine)" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_URIK2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.7.1.48</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : gtp + uri --&gt; gdp + h + ump</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2066#ABBREVIATION:udk#ECNUMBERS:2.7.1.48#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:uridine/cytidine kinase#ABBREVIATION:Udk#</html:p>
                    <html:p>GENE ASSOCIATION: (b2066)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_gtp_c" />
                    <speciesReference species="M_uri_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_gdp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_URIt2r" name="uridine transport in via proton symport, reversible">
                <notes>
                    <html:p>Abbreviation: R_URIt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + uri[e] &lt;==&gt; h[c] + uri[c]</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_uri_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_uri_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_USHD" name="UDP-sugar hydrolase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_USHD</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Cell Envelope Biosynthesis</html:p>
                    <html:p>Equation: [c] : h2o + u23ga --&gt; (2) h + lipidX + ump</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>tv
JLR- EC 3.6.1.45</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0480#ABBREVIATION:ushA#ECNUMBERS:3.6.1.45#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:_5'-nucleotidase / UDP-sugar hydrolase#ABBREVIATION:UshA#</html:p>
                    <html:p>GENE ASSOCIATION: (b0480)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_u23ga_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" stoichiometry="2" />
                    <speciesReference species="M_lipidX_c" />
                    <speciesReference species="M_ump_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_VALTA" name="valine transaminase">
                <notes>
                    <html:p>Abbreviation: R_VALTA</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.6.1.42</html:p>
                    <html:p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</html:p>
                    <html:p>Equation: [c] : akg + val-L &lt;==&gt; 3mob + glu-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3770#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3770)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_akg_c" />
                    <speciesReference species="M_val_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_3mob_c" />
                    <speciesReference species="M_glu_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_VALabc" name="L-valine transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_VALabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + val-L[e] --&gt; adp[c] + h[c] + pi[c] + val-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3454#ABBREVIATION:livF#</html:p>
                    <html:p>LOCUS:b3455#ABBREVIATION:livG#</html:p>
                    <html:p>LOCUS:b3456#ABBREVIATION:livM#</html:p>
                    <html:p>LOCUS:b3457#ABBREVIATION:livH#</html:p>
                    <html:p>LOCUS:b3460#ABBREVIATION:livJ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC, branced chain AA (periplasm)#ABBREVIATION:LivJ#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivF#</html:p>
                    <html:p>NAME:ABC, branced chain AA (atp)#ABBREVIATION:LivG#</html:p>
                    <html:p>NAME:ABC, branced chain AA (membrane)#ABBREVIATION:LivH#</html:p>
                    <html:p>NAME:ABC, branced chain AA #ABBREVIATION:LivM#</html:p>
                    <html:p>GENE ASSOCIATION: (b3455) and (b3454) and (b3460) and (b3457) and (b3456)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_val_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_val_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_VALt2r" name="L-valine reversible transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_VALt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + val-L[e] &lt;==&gt; h[c] + val-L[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0401#ABBREVIATION:brnQ#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Branched chain amino acid transport system II carrier protein#ABBREVIATION:BrnQ#</html:p>
                    <html:p>GENE ASSOCIATION: (b0401)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_val_L_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_val_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_VPAMT" name="Valine-pyruvate aminotransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_VPAMT</html:p>
                    <html:p>Synonyms: _1</html:p>
                    <html:p>EC Number: 2.6.1.66</html:p>
                    <html:p>SUBSYSTEM: Alanine and Aspartate Metabolism</html:p>
                    <html:p>Equation: [c] : 3mob + ala-L --&gt; pyr + val-L</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3572#ABBREVIATION:avtA#ECNUMBERS:2.6.1.66#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:valine-pyruvate aminotransferase#ABBREVIATION:AvtA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3572)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_3mob_c" />
                    <speciesReference species="M_ala_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_pyr_c" />
                    <speciesReference species="M_val_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_X5PL3E" name="L-xylulose 5-phosphate 3-epimerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_X5PL3E</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : xu5p-L --&gt; ru5p-L</html:p>
                    <html:p>Confidence Level: 4</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4197#ABBREVIATION:ulaE#ECNUMBERS:-5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:L-xylulose 5-phosphate 3-epimerase#ABBREVIATION:SgaU#</html:p>
                    <html:p>GENE ASSOCIATION: (b4197)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xu5p_L_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ru5p_L_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XANt" name="xanthine reversible transport">
                <notes>
                    <html:p>Abbreviation: R_XANt</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: xan[e] &lt;==&gt; xan[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>NCD</html:p>
                    <html:p>genes:</html:p>
                    <html:p>none</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>none</html:p>
                    <html:p>GENE ASSOCIATION: </html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xan_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XANt2" name="xanthine transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XANt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Putative Transporters</html:p>
                    <html:p>Equation: h[e] + xan[e] --&gt; h[c] + xan[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3654#ABBREVIATION:yicE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:putative puring/xanthine transport, NCS2#ABBREVIATION:YicE#</html:p>
                    <html:p>GENE ASSOCIATION: (b3654)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_xan_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_xan_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XPPT" name="xanthine phosphoribosyltransferase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XPPT</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 2.4.2.22</html:p>
                    <html:p>SUBSYSTEM: Nucleotide Salvage Pathway</html:p>
                    <html:p>Equation: [c] : prpp + xan --&gt; ppi + xmp</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b0238#ABBREVIATION:gpt#ECNUMBERS:2.4.2.22#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:Xanthine guanine phosphoribosyl transferase#ABBREVIATION:Gpt#</html:p>
                    <html:p>GENE ASSOCIATION: (b0238)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_prpp_c" />
                    <speciesReference species="M_xan_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_ppi_c" />
                    <speciesReference species="M_xmp_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XTSNt2r" name="Xanthosine transport via proton symport">
                <notes>
                    <html:p>Abbreviation: R_XTSNt2r</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + xtsn[e] &lt;==&gt; h[c] + xtsn[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b2406#ABBREVIATION:xapB#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xanthosine H symporter#ABBREVIATION:XapB#</html:p>
                    <html:p>GENE ASSOCIATION: (b2406)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_xtsn_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_xtsn_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XYLI1" name="xylose isomerase">
                <notes>
                    <html:p>Abbreviation: R_XYLI1</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.5</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : xyl-D &lt;==&gt; xylu-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>Some enzymes also convert D-glucose to D-fructose</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3565#ABBREVIATION:xylA#ECNUMBERS:5.3.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-xylose isomerase#ABBREVIATION:XylA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3565)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_xyl_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_xylu_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XYLI2i" name="xylose isomerase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XYLI2i</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>EC Number: 5.3.1.5</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : fru --&gt; glc-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>JLR</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3565#ABBREVIATION:xylA#ECNUMBERS:5.3.1.5#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:D-xylose isomerase#ABBREVIATION:XylA#</html:p>
                    <html:p>GENE ASSOCIATION: (b3565)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_fru_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_glc_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XYLK" name="xylulokinase" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XYLK</html:p>
                    <html:p>Synonyms: _3</html:p>
                    <html:p>EC Number: 2.7.1.17</html:p>
                    <html:p>SUBSYSTEM: Alternate Carbon Metabolism</html:p>
                    <html:p>Equation: [c] : atp + xylu-D --&gt; adp + h + xu5p-D</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3564#ABBREVIATION:xylB#ECNUMBERS:2.7.1.17,-!-,2.7.1.-#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:xylulokinase#ABBREVIATION:XylB#</html:p>
                    <html:p>GENE ASSOCIATION: (b3564)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_xylu_D_c" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_xu5p_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XYLabc" name="D-xylose transport via ABC system" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XYLabc</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: atp[c] + h2o[c] + xyl-D[e] --&gt; adp[c] + h[c] + pi[c] + xyl-D[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b3566#ABBREVIATION:xylF#</html:p>
                    <html:p>LOCUS:b3567#ABBREVIATION:xylG#</html:p>
                    <html:p>LOCUS:b3568#ABBREVIATION:xylH#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:ABC transport, xylose (periplasm)#ABBREVIATION:XylF#</html:p>
                    <html:p>NAME:ABC transport, xylose (atp)#ABBREVIATION:XylG#</html:p>
                    <html:p>NAME:ABC transport, xylose (membrane)#ABBREVIATION:XylH#</html:p>
                    <html:p>GENE ASSOCIATION: (b3568) and (b3566) and (b3567)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_atp_c" />
                    <speciesReference species="M_h2o_c" />
                    <speciesReference species="M_xyl_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_adp_c" />
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_pi_c" />
                    <speciesReference species="M_xyl_D_c" />
                </listOfProducts>
            </reaction>
            <reaction id="R_XYLt2" name="D-xylose transport in via proton symport" reversible="false">
                <notes>
                    <html:p>Abbreviation: R_XYLt2</html:p>
                    <html:p>Synonyms: _0</html:p>
                    <html:p>SUBSYSTEM: Transport, Extracellular</html:p>
                    <html:p>Equation: h[e] + xyl-D[e] --&gt; h[c] + xyl-D[c]</html:p>
                    <html:p>Confidence Level: 0</html:p>
                    <html:p>genes:</html:p>
                    <html:p>LOCUS:b4031#ABBREVIATION:xylE#</html:p>
                    <html:p>proteins:</html:p>
                    <html:p>NAME:MFS, xylose:proton symport#ABBREVIATION:XylE#</html:p>
                    <html:p>GENE ASSOCIATION: (b4031)</html:p>
                </notes>
                <listOfReactants>
                    <speciesReference species="M_h_e" />
                    <speciesReference species="M_xyl_D_e" />
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="M_h_c" />
                    <speciesReference species="M_xyl_D_c" />
                </listOfProducts>
            </reaction>
        </listOfReactions>
    </model>
</sbml>